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The map label for this gene is gcvT [H]

Identifier: 89054979

GI number: 89054979

Start: 2484670

End: 2487090

Strand: Direct

Name: gcvT [H]

Synonym: Jann_2488

Alternate gene names: 89054979

Gene position: 2484670-2487090 (Clockwise)

Preceding gene: 89054978

Following gene: 89054980

Centisome position: 57.54

GC content: 63.53

Gene sequence:

>2421_bases
ATGAAATCCCACACCCATGTCTGTATCATCGGCGGCGGCGTCATCGGCTGCTCCGTCGCCTACCACCTGACGAAACTGGG
CTGGTCTGATGTCACGTTGCTGGAACGGTCTGAGCTGACATCCGGCTCCACCTGGCACGCGGCGGGCGGCTTTCATACCT
TGAACGGCGATACCAATATGGCGGCGCTGCAAGGCTACACGATCCGTCTCTATAAAGAGCTGGAGGAGCTGACGGGGATG
TCCTGCGGGCTGCACCATGTGGGTGGCGTGACCCTCGCCGACACGCCGGAGCGGCTGGACATGCTGAAGGCCGAGCGCGC
CAAGCATCGGTTCATGGGGTTGGAGACTGAAATCATCGGCCCGGAGGAGATCGCCGAACTTGCGCCGATCACAAATGTGG
ATGGCATCCTCGGCGGGCTGTATGATCCGCTTGACGGCCATCTGGACCCCTCCGGCACCACCTATGCATATGCCAAGGCC
GCGCGGATGGGCGGGACGGAAATTCACCTCCATAGCAAAGTGTTAGAGACCAATGCTCGTGTGGATGGATCGTGGGAGAT
TGTGACAGACAAGGGCACGATCATCGCCGAGCATGTGGTGAACGCCGCGGGCCTTTGGGCGCGGGAAGTGGCGGCGATGG
CGGGCTGCTATCTGCCCCTGCATCCGATGGAGCACCAATATCTGGTCACGGAAGAGACGCCCGAGATCTATGGGCGCGAC
ACCGAGCATCCCCACGTCATGGACCCGGCGGGCGAAAGCTATCTGCGCCAGGAAGGGCGCGGGCTGTGTATCGGGTTTTA
TGAGAAAACCTGCCGCCCCTGGGCCGTGGATGGCACGCCCTGGGACTTCGGTCATGAATTGCTGCCCGATGACTTCGACA
AGATCGAGGACAGCATCGCCTTCGCCTTCAAACGCTTCCCGGTTCTGGAACGGGCCGGCATCAAATCCGTCGTCCACGGC
CCCTTCACCTTTGCGCCGGATGGCAACCCGCTTGTCGGCCCCGTCCCGGGCCTGCGCAATTACTGGTCCGCCTGCGGCGT
GATGGCGGGGTTCAGCCAGGGCGGCGGCGTCGGCCTGTCGCTGGCGCAATGGATGGTGGAGGGCGAGGCGGAGCGCGACG
TGATGGCGATGGATGTCGCGCGCTTCGGGCGCTGGATCACGCCAAGCTACACCCTGCCCAAGGTGGTCGAGAATTATCAG
ACGCGGTTTTCCGTGGTGTACCCTAACGAGGAACTCCCCGCCGCCCGGCCCGTCCGCACCACGCCGATGTATGATGTCTT
TGACAAGATGGGCGCGGTCTGGGGCCAGCAATATGGGTTGGAAGTGCCGAATTACTTCGCGGGACCTGGGGAGCCGAGAT
ACGAGGTCCCGTCCTTCCGTCGGTCAAATGCATGGGAGGCCACGGCGCGCGAGGTCAAAGCCGTGCGCGAGGGCGTCGGC
ATCAATGAGGTGCAGAATTTCGGCAAATACGACGTTCAAGGCCCCGGGGCGCGGGCCTGGCTGGACCGGGTTCTGGCGGG
CCGCATCCCAAAGCCGGGGCGGCTGTCCCTGACCCCCATGCTGTCACCCAAGGGCAGGATTATCGGCGACTTTACAGTCA
CGTGCCTGTCGGAGGAGCACTTTTTGCTGACCGGGTCCTACGGCGCGCAGGATTACCACATGCGCTGGTTCATGGCGCAG
GCGCCGGATGCCTCCGCAGGGGACGTGACCCTCGACAACGTCTCGGACCGGCGCACCGGGTTCCAGATCGCGGGCCCCCA
CGCGCGGGAGGTGTTGCAAGCCGTTACGCGGGACGACGTCAGCGACATGGCGTTCATGGATGTCCGCCAGCTTCACATCG
GATATTCTACGGCAATTGTGCAAAGGGTCAGCTACACCGGCGATCTGGGGTATGAGATCTATGTCGACGCGATGGAGCAG
CGCGCCCTTTGGAACGTGCTTTGGGCCGCCGGAGAGCCGCACGGCATGCGCCCCTTCGGGATGCGCGCGATGATGTCGCT
CAGGCTCGACAAGTTCTTCGGGTCGTGGATGCGAGAGTTCTCGCCCGATTATACACCCGCTGAAACGGGTCTCGACCGGT
TCATCTCCTGGAAGAAAAACGTCGATTTCATTGGCCGCGCCGCGGCGGACCGCGCCCGCTCCTCCGCGCCGGAGCGCGTC
CTCGCCGCGTTTGAGGTGGATGCCGCAGATGCAGACGTGGTGGCGTATGAGCCGATCTGGATCGACGGGCATGTTGCAGG
CTTCTGCACGTCGGGCGGGTATTCACACACCGCAGGCAAATCCGTCGCGCTGGGGTTTGTCCCCCGGGACAAGGCCACGG
ACGGCCTGAGCGTCGAGATCGAAATCCTCGGAGAGATGCGCCCGGCGCGGTTGATCACACGGCCGTTGTTCGACGGCGAA
GACACGCGGATGCGTGGATGA

Upstream 100 bases:

>100_bases
CACGCGCGCCTTGGTCAACGCGGACACGCAGATGTCGCAAACGCACTTGCCCCGGCCCCCGCCCTGCCCTCACATGGCGC
AAACCCACCGCGGAGGCCCC

Downstream 100 bases:

>100_bases
GCGCGCTGATCCTCTTGCTTGCCGCAGGCACCTCAACCCGCATGCGCGGCACCGACAAGCTATTGGAACCGGTCGATAAT
CAGCCCCTTCTGCGCCTGAT

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 806; Mature: 806

Protein sequence:

>806_residues
MKSHTHVCIIGGGVIGCSVAYHLTKLGWSDVTLLERSELTSGSTWHAAGGFHTLNGDTNMAALQGYTIRLYKELEELTGM
SCGLHHVGGVTLADTPERLDMLKAERAKHRFMGLETEIIGPEEIAELAPITNVDGILGGLYDPLDGHLDPSGTTYAYAKA
ARMGGTEIHLHSKVLETNARVDGSWEIVTDKGTIIAEHVVNAAGLWAREVAAMAGCYLPLHPMEHQYLVTEETPEIYGRD
TEHPHVMDPAGESYLRQEGRGLCIGFYEKTCRPWAVDGTPWDFGHELLPDDFDKIEDSIAFAFKRFPVLERAGIKSVVHG
PFTFAPDGNPLVGPVPGLRNYWSACGVMAGFSQGGGVGLSLAQWMVEGEAERDVMAMDVARFGRWITPSYTLPKVVENYQ
TRFSVVYPNEELPAARPVRTTPMYDVFDKMGAVWGQQYGLEVPNYFAGPGEPRYEVPSFRRSNAWEATAREVKAVREGVG
INEVQNFGKYDVQGPGARAWLDRVLAGRIPKPGRLSLTPMLSPKGRIIGDFTVTCLSEEHFLLTGSYGAQDYHMRWFMAQ
APDASAGDVTLDNVSDRRTGFQIAGPHAREVLQAVTRDDVSDMAFMDVRQLHIGYSTAIVQRVSYTGDLGYEIYVDAMEQ
RALWNVLWAAGEPHGMRPFGMRAMMSLRLDKFFGSWMREFSPDYTPAETGLDRFISWKKNVDFIGRAAADRARSSAPERV
LAAFEVDAADADVVAYEPIWIDGHVAGFCTSGGYSHTAGKSVALGFVPRDKATDGLSVEIEILGEMRPARLITRPLFDGE
DTRMRG

Sequences:

>Translated_806_residues
MKSHTHVCIIGGGVIGCSVAYHLTKLGWSDVTLLERSELTSGSTWHAAGGFHTLNGDTNMAALQGYTIRLYKELEELTGM
SCGLHHVGGVTLADTPERLDMLKAERAKHRFMGLETEIIGPEEIAELAPITNVDGILGGLYDPLDGHLDPSGTTYAYAKA
ARMGGTEIHLHSKVLETNARVDGSWEIVTDKGTIIAEHVVNAAGLWAREVAAMAGCYLPLHPMEHQYLVTEETPEIYGRD
TEHPHVMDPAGESYLRQEGRGLCIGFYEKTCRPWAVDGTPWDFGHELLPDDFDKIEDSIAFAFKRFPVLERAGIKSVVHG
PFTFAPDGNPLVGPVPGLRNYWSACGVMAGFSQGGGVGLSLAQWMVEGEAERDVMAMDVARFGRWITPSYTLPKVVENYQ
TRFSVVYPNEELPAARPVRTTPMYDVFDKMGAVWGQQYGLEVPNYFAGPGEPRYEVPSFRRSNAWEATAREVKAVREGVG
INEVQNFGKYDVQGPGARAWLDRVLAGRIPKPGRLSLTPMLSPKGRIIGDFTVTCLSEEHFLLTGSYGAQDYHMRWFMAQ
APDASAGDVTLDNVSDRRTGFQIAGPHAREVLQAVTRDDVSDMAFMDVRQLHIGYSTAIVQRVSYTGDLGYEIYVDAMEQ
RALWNVLWAAGEPHGMRPFGMRAMMSLRLDKFFGSWMREFSPDYTPAETGLDRFISWKKNVDFIGRAAADRARSSAPERV
LAAFEVDAADADVVAYEPIWIDGHVAGFCTSGGYSHTAGKSVALGFVPRDKATDGLSVEIEILGEMRPARLITRPLFDGE
DTRMRG
>Mature_806_residues
MKSHTHVCIIGGGVIGCSVAYHLTKLGWSDVTLLERSELTSGSTWHAAGGFHTLNGDTNMAALQGYTIRLYKELEELTGM
SCGLHHVGGVTLADTPERLDMLKAERAKHRFMGLETEIIGPEEIAELAPITNVDGILGGLYDPLDGHLDPSGTTYAYAKA
ARMGGTEIHLHSKVLETNARVDGSWEIVTDKGTIIAEHVVNAAGLWAREVAAMAGCYLPLHPMEHQYLVTEETPEIYGRD
TEHPHVMDPAGESYLRQEGRGLCIGFYEKTCRPWAVDGTPWDFGHELLPDDFDKIEDSIAFAFKRFPVLERAGIKSVVHG
PFTFAPDGNPLVGPVPGLRNYWSACGVMAGFSQGGGVGLSLAQWMVEGEAERDVMAMDVARFGRWITPSYTLPKVVENYQ
TRFSVVYPNEELPAARPVRTTPMYDVFDKMGAVWGQQYGLEVPNYFAGPGEPRYEVPSFRRSNAWEATAREVKAVREGVG
INEVQNFGKYDVQGPGARAWLDRVLAGRIPKPGRLSLTPMLSPKGRIIGDFTVTCLSEEHFLLTGSYGAQDYHMRWFMAQ
APDASAGDVTLDNVSDRRTGFQIAGPHAREVLQAVTRDDVSDMAFMDVRQLHIGYSTAIVQRVSYTGDLGYEIYVDAMEQ
RALWNVLWAAGEPHGMRPFGMRAMMSLRLDKFFGSWMREFSPDYTPAETGLDRFISWKKNVDFIGRAAADRARSSAPERV
LAAFEVDAADADVVAYEPIWIDGHVAGFCTSGGYSHTAGKSVALGFVPRDKATDGLSVEIEILGEMRPARLITRPLFDGE
DTRMRG

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI24797151, Length=812, Percent_Identity=39.2857142857143, Blast_Score=579, Evalue=1e-165,
Organism=Homo sapiens, GI197927446, Length=865, Percent_Identity=31.3294797687861, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI21361378, Length=865, Percent_Identity=31.3294797687861, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI194306651, Length=786, Percent_Identity=30.4071246819338, Blast_Score=357, Evalue=2e-98,
Organism=Escherichia coli, GI1789272, Length=335, Percent_Identity=24.7761194029851, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994045, Length=794, Percent_Identity=28.9672544080605, Blast_Score=304, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI71994052, Length=801, Percent_Identity=28.7141073657928, Blast_Score=301, Evalue=8e-82,
Organism=Caenorhabditis elegans, GI32563613, Length=826, Percent_Identity=26.8765133171913, Blast_Score=235, Evalue=9e-62,
Organism=Drosophila melanogaster, GI20130091, Length=859, Percent_Identity=28.7543655413271, Blast_Score=318, Evalue=8e-87,
Organism=Drosophila melanogaster, GI28571104, Length=788, Percent_Identity=29.0609137055838, Blast_Score=309, Evalue=5e-84,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 88852; Mature: 88852

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSHTHVCIIGGGVIGCSVAYHLTKLGWSDVTLLERSELTSGSTWHAAGGFHTLNGDTNM
CCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEECCCCEEEECCCCCE
AALQGYTIRLYKELEELTGMSCGLHHVGGVTLADTPERLDMLKAERAKHRFMGLETEIIG
EECCCCHHHHHHHHHHHCCCCCCHHHCCCEEECCCHHHHHHHHHHHHHHHHCCCCEECCC
PEEIAELAPITNVDGILGGLYDPLDGHLDPSGTTYAYAKAARMGGTEIHLHSKVLETNAR
HHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCEEHHHHHHHCCCCEEEEEHHHHHCCCC
VDGSWEIVTDKGTIIAEHVVNAAGLWAREVAAMAGCYLPLHPMEHQYLVTEETPEIYGRD
CCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHCCCC
TEHPHVMDPAGESYLRQEGRGLCIGFYEKTCRPWAVDGTPWDFGHELLPDDFDKIEDSIA
CCCCCCCCCCCHHHHHHCCCEEEEEEHHHCCCCEECCCCCCCCCCCCCCCHHHHHHHHHH
FAFKRFPVLERAGIKSVVHGPFTFAPDGNPLVGPVPGLRNYWSACGVMAGFSQGGGVGLS
HHHHHCCHHHHHCCHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHH
LAQWMVEGEAERDVMAMDVARFGRWITPSYTLPKVVENYQTRFSVVYPNEELPAARPVRT
HHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCEEEEEECCCCCCCCCCCCC
TPMYDVFDKMGAVWGQQYGLEVPNYFAGPGEPRYEVPSFRRSNAWEATAREVKAVREGVG
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
INEVQNFGKYDVQGPGARAWLDRVLAGRIPKPGRLSLTPMLSPKGRIIGDFTVTCLSEEH
HHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEEEEEEECCCC
FLLTGSYGAQDYHMRWFMAQAPDASAGDVTLDNVSDRRTGFQIAGPHAREVLQAVTRDDV
EEEECCCCCCCEEEEEEEEECCCCCCCCEEECCCCCCCCCCEECCHHHHHHHHHHHHCCH
SDMAFMDVRQLHIGYSTAIVQRVSYTGDLGYEIYVDAMEQRALWNVLWAAGEPHGMRPFG
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCHHH
MRAMMSLRLDKFFGSWMREFSPDYTPAETGLDRFISWKKNVDFIGRAAADRARSSAPERV
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHH
LAAFEVDAADADVVAYEPIWIDGHVAGFCTSGGYSHTAGKSVALGFVPRDKATDGLSVEI
HEEEEECCCCCCEEEECCEEECCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCEEEE
EILGEMRPARLITRPLFDGEDTRMRG
EEECCCCCHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKSHTHVCIIGGGVIGCSVAYHLTKLGWSDVTLLERSELTSGSTWHAAGGFHTLNGDTNM
CCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEECCCCEEEECCCCCE
AALQGYTIRLYKELEELTGMSCGLHHVGGVTLADTPERLDMLKAERAKHRFMGLETEIIG
EECCCCHHHHHHHHHHHCCCCCCHHHCCCEEECCCHHHHHHHHHHHHHHHHCCCCEECCC
PEEIAELAPITNVDGILGGLYDPLDGHLDPSGTTYAYAKAARMGGTEIHLHSKVLETNAR
HHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCEEHHHHHHHCCCCEEEEEHHHHHCCCC
VDGSWEIVTDKGTIIAEHVVNAAGLWAREVAAMAGCYLPLHPMEHQYLVTEETPEIYGRD
CCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHCCCC
TEHPHVMDPAGESYLRQEGRGLCIGFYEKTCRPWAVDGTPWDFGHELLPDDFDKIEDSIA
CCCCCCCCCCCHHHHHHCCCEEEEEEHHHCCCCEECCCCCCCCCCCCCCCHHHHHHHHHH
FAFKRFPVLERAGIKSVVHGPFTFAPDGNPLVGPVPGLRNYWSACGVMAGFSQGGGVGLS
HHHHHCCHHHHHCCHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHH
LAQWMVEGEAERDVMAMDVARFGRWITPSYTLPKVVENYQTRFSVVYPNEELPAARPVRT
HHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCEEEEEECCCCCCCCCCCCC
TPMYDVFDKMGAVWGQQYGLEVPNYFAGPGEPRYEVPSFRRSNAWEATAREVKAVREGVG
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
INEVQNFGKYDVQGPGARAWLDRVLAGRIPKPGRLSLTPMLSPKGRIIGDFTVTCLSEEH
HHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEEEEEEECCCC
FLLTGSYGAQDYHMRWFMAQAPDASAGDVTLDNVSDRRTGFQIAGPHAREVLQAVTRDDV
EEEECCCCCCCEEEEEEEEECCCCCCCCEEECCCCCCCCCCEECCHHHHHHHHHHHHCCH
SDMAFMDVRQLHIGYSTAIVQRVSYTGDLGYEIYVDAMEQRALWNVLWAAGEPHGMRPFG
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCHHH
MRAMMSLRLDKFFGSWMREFSPDYTPAETGLDRFISWKKNVDFIGRAAADRARSSAPERV
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHH
LAAFEVDAADADVVAYEPIWIDGHVAGFCTSGGYSHTAGKSVALGFVPRDKATDGLSVEI
HEEEEECCCCCCEEEECCEEECCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCEEEE
EILGEMRPARLITRPLFDGEDTRMRG
EEECCCCCHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA