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The map label for this gene is aroB

Identifier: 89054978

GI number: 89054978

Start: 2483404

End: 2484516

Strand: Direct

Name: aroB

Synonym: Jann_2487

Alternate gene names: 89054978

Gene position: 2483404-2484516 (Clockwise)

Preceding gene: 89054977

Following gene: 89054979

Centisome position: 57.51

GC content: 65.68

Gene sequence:

>1113_bases
ATGAGCGATACGGTCCGGGTCGAGTTGGGCGCGCGCGCCTATGATGTTGAAATCGGGGCAGGTCTTATCGCCTCCGCCGG
GGCCCGCATCGCGCCGCTGCTGTCGCGGCCCAAAGTGTGGATCGTCACGGAAGAGACGGTCGCCGCCCTGCATATGGATG
CCCTGCGCGCCGGTCTTGACGCCGCCAATATCGCCAGCGAGGCCCTGGTTCTGCCCCCCGGCGAGGCCACCAAATCCTGG
CCGCATCTGCAACGCATCGCCGATTGGCTCCTGTCCGAGCGGGTGGAGCGCGCGGATATCGTGATTGCCTTCGGCGGCGG
CGTGATCGGTGATCTTGCGGGCTTTGCCGCCGCCATCCACCGGCGCGGCATCCGTTTTGTGCAGATCCCCACGTCACTTT
TGGCGCAGGTTGACAGCTCTGTCGGTGGCAAGACCGGTATCAACGCGCCACAAGGCAAGAACCTGATCGGCGCGTTTCAC
CAACCGTCGCTGGTGCTGGCCGACATCGACGTTCTGGGCACACTGATGCCGCGCGATTTTCTGGCGGGCTACGGCGAAGT
GGCGAAATACGGTATGCTCGGCGACGCCCCCTTCTTCGAGTGGCTGGAGGCCAACGGCCCCGCCATGGCCAAGGGTGACC
CCGCGCTGCGGCAAGAGGCGGTGCGCCGCTCCGTCCAGATGAAGGCAGATATCGTCGCCCGCGATGAGACGGAGCAGGGT
GATCGCGCGCTCCTCAACCTTGGCCACACGTTTTGTCATGCCCTGGAAGCCGCCACGGGGTATTCCGACCGGCTGCTGCA
TGGCGAAGGGGTCGCCATTGGCTGCGCCTTGGCGTTTGAGCTATCGGCCCGTCTGGGCCTGTGTTCGCAAGAAGACCCCA
GCCGCGTGCGCGCCCATCTGGCCGCCATGGGCACAAGGCGCGATCTGTCGGACATTCCCGGTGACCTGCCCGACGCAGAC
GCCCTCATCACGTTGATGGGCCAGGATAAAAAGGTCGTGGCAGGGCAACTCCGCTTCATCCTCGCGCGCGGCATCGGCCA
CGCGTTTGTCACTGCCGACGTGCCCACAGATGCGGTCAAAGCCCTCCTCACGGACGCGCTCGCCGGTCGATAG

Upstream 100 bases:

>100_bases
ACAAGGTCACGGTGCGGCCCGAATGGTCGATCGACGCGACCGCCGATCAGGTCATGGATATCCTGCGCCACAATGGCACT
GTGCCCGAGGCCGCCGCCCC

Downstream 100 bases:

>100_bases
CGCGCGCCGCTCCCCCTTTCATCTGGGCAAATACAACTCAATCCCGGCATCTCCACGCGCGCCTTGGTCAACGCGGACAC
GCAGATGTCGCAAACGCACT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSDTVRVELGARAYDVEIGAGLIASAGARIAPLLSRPKVWIVTEETVAALHMDALRAGLDAANIASEALVLPPGEATKSW
PHLQRIADWLLSERVERADIVIAFGGGVIGDLAGFAAAIHRRGIRFVQIPTSLLAQVDSSVGGKTGINAPQGKNLIGAFH
QPSLVLADIDVLGTLMPRDFLAGYGEVAKYGMLGDAPFFEWLEANGPAMAKGDPALRQEAVRRSVQMKADIVARDETEQG
DRALLNLGHTFCHALEAATGYSDRLLHGEGVAIGCALAFELSARLGLCSQEDPSRVRAHLAAMGTRRDLSDIPGDLPDAD
ALITLMGQDKKVVAGQLRFILARGIGHAFVTADVPTDAVKALLTDALAGR

Sequences:

>Translated_370_residues
MSDTVRVELGARAYDVEIGAGLIASAGARIAPLLSRPKVWIVTEETVAALHMDALRAGLDAANIASEALVLPPGEATKSW
PHLQRIADWLLSERVERADIVIAFGGGVIGDLAGFAAAIHRRGIRFVQIPTSLLAQVDSSVGGKTGINAPQGKNLIGAFH
QPSLVLADIDVLGTLMPRDFLAGYGEVAKYGMLGDAPFFEWLEANGPAMAKGDPALRQEAVRRSVQMKADIVARDETEQG
DRALLNLGHTFCHALEAATGYSDRLLHGEGVAIGCALAFELSARLGLCSQEDPSRVRAHLAAMGTRRDLSDIPGDLPDAD
ALITLMGQDKKVVAGQLRFILARGIGHAFVTADVPTDAVKALLTDALAGR
>Mature_369_residues
SDTVRVELGARAYDVEIGAGLIASAGARIAPLLSRPKVWIVTEETVAALHMDALRAGLDAANIASEALVLPPGEATKSWP
HLQRIADWLLSERVERADIVIAFGGGVIGDLAGFAAAIHRRGIRFVQIPTSLLAQVDSSVGGKTGINAPQGKNLIGAFHQ
PSLVLADIDVLGTLMPRDFLAGYGEVAKYGMLGDAPFFEWLEANGPAMAKGDPALRQEAVRRSVQMKADIVARDETEQGD
RALLNLGHTFCHALEAATGYSDRLLHGEGVAIGCALAFELSARLGLCSQEDPSRVRAHLAAMGTRRDLSDIPGDLPDADA
LITLMGQDKKVVAGQLRFILARGIGHAFVTADVPTDAVKALLTDALAGR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=369, Percent_Identity=43.9024390243902, Blast_Score=273, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6320332, Length=333, Percent_Identity=36.6366366366366, Blast_Score=176, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_JANSC (Q28PF8)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_510429.1
- ProteinModelPortal:   Q28PF8
- SMR:   Q28PF8
- STRING:   Q28PF8
- GeneID:   3934945
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_2487
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   GWIDESI
- PhylomeDB:   Q28PF8
- ProtClustDB:   PRK00002
- BioCyc:   JSP290400:JANN_2487-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 39069; Mature: 38938

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTVRVELGARAYDVEIGAGLIASAGARIAPLLSRPKVWIVTEETVAALHMDALRAGLD
CCCCEEEEECCEEEEEECCCCHHHHCCCHHHHHHCCCEEEEEEHHHHHHHHHHHHHHCCC
AANIASEALVLPPGEATKSWPHLQRIADWLLSERVERADIVIAFGGGVIGDLAGFAAAIH
HHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHH
RRGIRFVQIPTSLLAQVDSSVGGKTGINAPQGKNLIGAFHQPSLVLADIDVLGTLMPRDF
HCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCEEEEHHHHHHHHCCHHH
LAGYGEVAKYGMLGDAPFFEWLEANGPAMAKGDPALRQEAVRRSVQMKADIVARDETEQG
HHCHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCC
DRALLNLGHTFCHALEAATGYSDRLLHGEGVAIGCALAFELSARLGLCSQEDPSRVRAHL
HHHHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHH
AAMGTRRDLSDIPGDLPDADALITLMGQDKKVVAGQLRFILARGIGHAFVTADVPTDAVK
HHHCCCCCHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHH
ALLTDALAGR
HHHHHHHCCC
>Mature Secondary Structure 
SDTVRVELGARAYDVEIGAGLIASAGARIAPLLSRPKVWIVTEETVAALHMDALRAGLD
CCCEEEEECCEEEEEECCCCHHHHCCCHHHHHHCCCEEEEEEHHHHHHHHHHHHHHCCC
AANIASEALVLPPGEATKSWPHLQRIADWLLSERVERADIVIAFGGGVIGDLAGFAAAIH
HHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHH
RRGIRFVQIPTSLLAQVDSSVGGKTGINAPQGKNLIGAFHQPSLVLADIDVLGTLMPRDF
HCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCEEEEHHHHHHHHCCHHH
LAGYGEVAKYGMLGDAPFFEWLEANGPAMAKGDPALRQEAVRRSVQMKADIVARDETEQG
HHCHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCC
DRALLNLGHTFCHALEAATGYSDRLLHGEGVAIGCALAFELSARLGLCSQEDPSRVRAHL
HHHHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHH
AAMGTRRDLSDIPGDLPDADALITLMGQDKKVVAGQLRFILARGIGHAFVTADVPTDAVK
HHHCCCCCHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHH
ALLTDALAGR
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA