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The map label for this gene is yafC [H]

Identifier: 89054899

GI number: 89054899

Start: 2409682

End: 2410566

Strand: Reverse

Name: yafC [H]

Synonym: Jann_2408

Alternate gene names: 89054899

Gene position: 2410566-2409682 (Counterclockwise)

Preceding gene: 89054901

Following gene: 89054898

Centisome position: 55.83

GC content: 61.81

Gene sequence:

>885_bases
GTGCCGCACCCAGCCCCCGAGATCGCAGCTTTCGTGCGCGTTGTGGAGCTTGGATCCTTTGCATCGGTGGCGTCCGATAC
CGGGTACACATCCTCCGGCGTCTCCCGCATGGTCACACGGTTGGAGGAAAATTTTGGCACCAAGTTGTTTTTCAGATCAA
CGCGGCAGCTGTCCCTGACCCCTGACGGAGAGGCGTTCCTGCCACGGGCACGGTCCATTCTGGACGCGATCGAGGCGGCC
GGTGCCGACTTATCGGATGCAGCAGAGACCCCGCGCGGACATATCCGTCTGAACTGCGGCACGGCCTTCGCCAATCACAA
GCTGGCGCCACGTCTCGCGGACTTCGCAACGCGTTATCCGCATATCTCGCTTAGCATTTCGGTCACCGACCAACGGGTCG
ATCCGGTCGCGCGGCAAGCGGACGTGACGATCCGGGTTGGCGATCTGGCAGATAGCACCCTCATCGCCATCCCCTTGGGT
TCGGTCGCGCGCGTCATCGCCGCGAGCCCCGCTTATCTGGCGAAGCATGGAGAGCCCCAGATAGCACGGCACCTTCTGAA
ACATAATTGCCTGTTGTTGAACGGGTTTCCACATCAGGCCGCCTGGCCCTTTCTGGAAAAGGGTCAGCCGATCACGGTAT
CTGTCAAAGGGACCCTGACATCCGACAGCGCCGAGACGCTTCTGCACGCCGCTATATCCGGCGCGGGCATCATTCGACTG
GGCGATTTTCTGGGGGCCGATGCGCTGGCGTCGGGTCAGCTGGTTCCGATCCTGACCAGGACACATGATCCTGTCCGGCA
ACCCATAACGGCGCTGGTGCCGCCCGGTCGACACTCCGTTCCGAGGGTGCGGGCGCTTTTGAACTTCCTCAAAGCGAACG
TCTGA

Upstream 100 bases:

>100_bases
TCCTTGGCTTGGGGGAGGCGACCTGATCAGCCTATTCTTGACCCAGAGTCGGGAAAACAGCAGAATATGCAACTCACCCT
TGCTTTAAAGTCATCAATAC

Downstream 100 bases:

>100_bases
CGGGGCCCGGACCCCGCGCGGCGCACAGTCGGGCAACGCGCCGCCGGGCTCGAACCGGATGTAGGATGAAGCGCGGCATC
CTGCGATATGGCGGGTCGGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MPHPAPEIAAFVRVVELGSFASVASDTGYTSSGVSRMVTRLEENFGTKLFFRSTRQLSLTPDGEAFLPRARSILDAIEAA
GADLSDAAETPRGHIRLNCGTAFANHKLAPRLADFATRYPHISLSISVTDQRVDPVARQADVTIRVGDLADSTLIAIPLG
SVARVIAASPAYLAKHGEPQIARHLLKHNCLLLNGFPHQAAWPFLEKGQPITVSVKGTLTSDSAETLLHAAISGAGIIRL
GDFLGADALASGQLVPILTRTHDPVRQPITALVPPGRHSVPRVRALLNFLKANV

Sequences:

>Translated_294_residues
MPHPAPEIAAFVRVVELGSFASVASDTGYTSSGVSRMVTRLEENFGTKLFFRSTRQLSLTPDGEAFLPRARSILDAIEAA
GADLSDAAETPRGHIRLNCGTAFANHKLAPRLADFATRYPHISLSISVTDQRVDPVARQADVTIRVGDLADSTLIAIPLG
SVARVIAASPAYLAKHGEPQIARHLLKHNCLLLNGFPHQAAWPFLEKGQPITVSVKGTLTSDSAETLLHAAISGAGIIRL
GDFLGADALASGQLVPILTRTHDPVRQPITALVPPGRHSVPRVRALLNFLKANV
>Mature_293_residues
PHPAPEIAAFVRVVELGSFASVASDTGYTSSGVSRMVTRLEENFGTKLFFRSTRQLSLTPDGEAFLPRARSILDAIEAAG
ADLSDAAETPRGHIRLNCGTAFANHKLAPRLADFATRYPHISLSISVTDQRVDPVARQADVTIRVGDLADSTLIAIPLGS
VARVIAASPAYLAKHGEPQIARHLLKHNCLLLNGFPHQAAWPFLEKGQPITVSVKGTLTSDSAETLLHAAISGAGIIRLG
DFLGADALASGQLVPILTRTHDPVRQPITALVPPGRHSVPRVRALLNFLKANV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=297, Percent_Identity=37.7104377104377, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1789440, Length=256, Percent_Identity=29.6875, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI87081978, Length=286, Percent_Identity=29.3706293706294, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI145693193, Length=252, Percent_Identity=32.1428571428571, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787128, Length=294, Percent_Identity=27.5510204081633, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789639, Length=284, Percent_Identity=28.5211267605634, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787589, Length=258, Percent_Identity=28.2945736434109, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI157672245, Length=165, Percent_Identity=33.9393939393939, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789173, Length=242, Percent_Identity=28.099173553719, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788706, Length=282, Percent_Identity=25.177304964539, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790011, Length=248, Percent_Identity=27.0161290322581, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786448, Length=247, Percent_Identity=25.5060728744939, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI145693105, Length=171, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082132, Length=253, Percent_Identity=26.4822134387352, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786713, Length=124, Percent_Identity=33.0645161290323, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31325; Mature: 31194

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHPAPEIAAFVRVVELGSFASVASDTGYTSSGVSRMVTRLEENFGTKLFFRSTRQLSLT
CCCCHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCEEEEC
PDGEAFLPRARSILDAIEAAGADLSDAAETPRGHIRLNCGTAFANHKLAPRLADFATRYP
CCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCC
HISLSISVTDQRVDPVARQADVTIRVGDLADSTLIAIPLGSVARVIAASPAYLAKHGEPQ
EEEEEEEEECCCCCHHHHHCCEEEEECCCCCCEEEEEEHHHHHHHHHCCCHHHHHCCCHH
IARHLLKHNCLLLNGFPHQAAWPFLEKGQPITVSVKGTLTSDSAETLLHAAISGAGIIRL
HHHHHHHCCEEEEECCCCHHCCCHHHCCCEEEEEEEEEECCCHHHHHHHHHHCCCCEEEE
GDFLGADALASGQLVPILTRTHDPVRQPITALVPPGRHSVPRVRALLNFLKANV
HHHHCCCHHCCCCEEEEEECCCCHHHCCHHEECCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PHPAPEIAAFVRVVELGSFASVASDTGYTSSGVSRMVTRLEENFGTKLFFRSTRQLSLT
CCCHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCEEEEC
PDGEAFLPRARSILDAIEAAGADLSDAAETPRGHIRLNCGTAFANHKLAPRLADFATRYP
CCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCC
HISLSISVTDQRVDPVARQADVTIRVGDLADSTLIAIPLGSVARVIAASPAYLAKHGEPQ
EEEEEEEEECCCCCHHHHHCCEEEEECCCCCCEEEEEEHHHHHHHHHCCCHHHHHCCCHH
IARHLLKHNCLLLNGFPHQAAWPFLEKGQPITVSVKGTLTSDSAETLLHAAISGAGIIRL
HHHHHHHCCEEEEECCCCHHCCCHHHCCCEEEEEEEEEECCCHHHHHHHHHHCCCCEEEE
GDFLGADALASGQLVPILTRTHDPVRQPITALVPPGRHSVPRVRALLNFLKANV
HHHHCCCHHCCCCEEEEEECCCCHHHCCHHEECCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]