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The map label for this gene is xylB [H]

Identifier: 89054898

GI number: 89054898

Start: 2407955

End: 2409418

Strand: Reverse

Name: xylB [H]

Synonym: Jann_2407

Alternate gene names: 89054898

Gene position: 2409418-2407955 (Counterclockwise)

Preceding gene: 89054899

Following gene: 89054897

Centisome position: 55.8

GC content: 64.75

Gene sequence:

>1464_bases
ATGCCGAACAGACTGACCCTTGGGATCGACGTCGGAACGACATCCGTGAAGGCCGGTATCGTCGACGGGTCCGGGCGTGT
CGTCGCCCGGTTCGCGCAAAGCTACCCCACCTTGCGCCGCGGATCGGATATCGCGGAACAGGACCCGGACGATTGGGTAC
GATTGATATCCGATGCGATGGCGTCCTTCGCGGACTTCGAGATCTCGGCGATTGGTATCACGGGTCAGGTCAACACCCAT
GTATTCGTGGACCGCGAGGGCACGGCATTGTTGCCTGCAATCTTGTGGCAGGATGGCCGTGCGGGCGGTGAAGCGGCCGG
CCTGGATGCGCGTGTAAGCGCGGCGCAGAAGCAGGCGTGGTGGGGCGCGCCGATGCCGATTGATGCCTCCCACGCCTGTT
CGCGCATGGCCTGGGTCGCCCGCCACCACCCCGATATCTGGGAGAAGACGCGATGGGTGATGCTGCCCAAAGACTATTGC
CTTCTCAAACTGACGGGGGAGGCCACGACCGACCCAATCTCCAATATCGGCCTTGTGGACAACACCCACGCCTATATCGC
GGAGGTGTTTGACCTCGTGCCCGGCGCGGCGGACCGCAAGGTACCGCTGGTGCCGGTCTGCGACGTGGTTGGCACCGTCG
CGCAGGGGCCATTTGCGGGGGTGCCCGTTGTGTCGGGCACGATGGATGCCTGGGCGGGCCTGGTCGGCGCGGGCGGGGCG
AAAGACGGCTCCACCGTCTATCTCAGCGGAACCAGTGAAATCCTGGGGATTTCATCGCACGATGTGGTGCCCACGCCCGG
CATCATTGTCTTCCCCGAAGCGGATGGCATCCGGCTGCACGCGGCACCGACGCAATCCGGCGGGGATGCCAAGGTCTGGT
TTTCGCAAGCCGGCGGCGTGTCCCTTGACCAGATGACCGAGCTGGTCGCACGCACCGAAAGACGCGCGGCGACGCCCCTG
TTCCTGCCCCAGTTGCAGGGAGAGCGCGCGCCGTTATGGGACGCGGATCTGCGCGCGGCCTTCCTGGGGGTTGGCCGCCA
GACCAATCAGCAGGATCTGGCCCGCGCGGTCTATGAAGGCGTGGCGATGTCCGCCCGCATGGCCCTTGAGGCGCTTCAGA
AATCGGCGGGCGTTGTCAGTGACACCATCGCGTGCGGCGGCGGTGGGTTTCAATCCGACCCGTGGGCTCAAATCCGGGCC
GATATCCTGGGTGTCGAGTTGACATGCCTGGCCGCCAAAGACCCGGGCATATTGGGCGCGGCGGCGATGGCAGCCATCGG
CGTGGGGCACTTCCGGGCCTTCGGGGAGGCCTATGACGCCCTGGCCGTGTTTGACCGCACATTCACCCCAGATCCGGCGT
CCCACACCCATTACAACGACCTGTTCGACCTGTACCGGGACGCGATTGCAGTGAATGCAGATCTCGGCAAACGCCTGTCA
AAACTGGATTTCTCGACCGTTTGA

Upstream 100 bases:

>100_bases
CAGGACCCCAAACCTGCACATGTGCCCAAACGCGGCGCCCGATGGGCTGGAACTCGACCAGAGTTTCGGGGAATATCCGC
CCGAGCGCAGAGGAAGCCGA

Downstream 100 bases:

>100_bases
GCCGGAAAATCCGATTTCTGGTCTGGGAACCTTGCGAAAAACCCTTACAAAATGGCCGCCAAGGCCTTCTGAGAGGGCCA
CAAAGGGGAGAGAACCATGA

Product: carbohydrate kinase

Products: ADP; D-xylulose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MPNRLTLGIDVGTTSVKAGIVDGSGRVVARFAQSYPTLRRGSDIAEQDPDDWVRLISDAMASFADFEISAIGITGQVNTH
VFVDREGTALLPAILWQDGRAGGEAAGLDARVSAAQKQAWWGAPMPIDASHACSRMAWVARHHPDIWEKTRWVMLPKDYC
LLKLTGEATTDPISNIGLVDNTHAYIAEVFDLVPGAADRKVPLVPVCDVVGTVAQGPFAGVPVVSGTMDAWAGLVGAGGA
KDGSTVYLSGTSEILGISSHDVVPTPGIIVFPEADGIRLHAAPTQSGGDAKVWFSQAGGVSLDQMTELVARTERRAATPL
FLPQLQGERAPLWDADLRAAFLGVGRQTNQQDLARAVYEGVAMSARMALEALQKSAGVVSDTIACGGGGFQSDPWAQIRA
DILGVELTCLAAKDPGILGAAAMAAIGVGHFRAFGEAYDALAVFDRTFTPDPASHTHYNDLFDLYRDAIAVNADLGKRLS
KLDFSTV

Sequences:

>Translated_487_residues
MPNRLTLGIDVGTTSVKAGIVDGSGRVVARFAQSYPTLRRGSDIAEQDPDDWVRLISDAMASFADFEISAIGITGQVNTH
VFVDREGTALLPAILWQDGRAGGEAAGLDARVSAAQKQAWWGAPMPIDASHACSRMAWVARHHPDIWEKTRWVMLPKDYC
LLKLTGEATTDPISNIGLVDNTHAYIAEVFDLVPGAADRKVPLVPVCDVVGTVAQGPFAGVPVVSGTMDAWAGLVGAGGA
KDGSTVYLSGTSEILGISSHDVVPTPGIIVFPEADGIRLHAAPTQSGGDAKVWFSQAGGVSLDQMTELVARTERRAATPL
FLPQLQGERAPLWDADLRAAFLGVGRQTNQQDLARAVYEGVAMSARMALEALQKSAGVVSDTIACGGGGFQSDPWAQIRA
DILGVELTCLAAKDPGILGAAAMAAIGVGHFRAFGEAYDALAVFDRTFTPDPASHTHYNDLFDLYRDAIAVNADLGKRLS
KLDFSTV
>Mature_486_residues
PNRLTLGIDVGTTSVKAGIVDGSGRVVARFAQSYPTLRRGSDIAEQDPDDWVRLISDAMASFADFEISAIGITGQVNTHV
FVDREGTALLPAILWQDGRAGGEAAGLDARVSAAQKQAWWGAPMPIDASHACSRMAWVARHHPDIWEKTRWVMLPKDYCL
LKLTGEATTDPISNIGLVDNTHAYIAEVFDLVPGAADRKVPLVPVCDVVGTVAQGPFAGVPVVSGTMDAWAGLVGAGGAK
DGSTVYLSGTSEILGISSHDVVPTPGIIVFPEADGIRLHAAPTQSGGDAKVWFSQAGGVSLDQMTELVARTERRAATPLF
LPQLQGERAPLWDADLRAAFLGVGRQTNQQDLARAVYEGVAMSARMALEALQKSAGVVSDTIACGGGGFQSDPWAQIRAD
ILGVELTCLAAKDPGILGAAAMAAIGVGHFRAFGEAYDALAVFDRTFTPDPASHTHYNDLFDLYRDAIAVNADLGKRLSK
LDFSTV

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393575, Length=391, Percent_Identity=21.227621483376, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI189409120, Length=445, Percent_Identity=20.8988764044944, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI4504007, Length=445, Percent_Identity=20.8988764044944, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI42794763, Length=448, Percent_Identity=20.7589285714286, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1789987, Length=483, Percent_Identity=29.1925465838509, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1790005, Length=504, Percent_Identity=25.5952380952381, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787789, Length=507, Percent_Identity=23.8658777120316, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789168, Length=495, Percent_Identity=26.8686868686869, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790361, Length=490, Percent_Identity=23.469387755102, Blast_Score=86, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17535599, Length=451, Percent_Identity=23.059866962306, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17864214, Length=471, Percent_Identity=22.9299363057325, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24654573, Length=403, Percent_Identity=23.3250620347395, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24655555, Length=414, Percent_Identity=21.7391304347826, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24655560, Length=414, Percent_Identity=21.7391304347826, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24655570, Length=414, Percent_Identity=21.7391304347826, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24655574, Length=414, Percent_Identity=21.7391304347826, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24655565, Length=414, Percent_Identity=21.7391304347826, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: 2.7.1.17

Molecular weight: Translated: 51447; Mature: 51315

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNRLTLGIDVGTTSVKAGIVDGSGRVVARFAQSYPTLRRGSDIAEQDPDDWVRLISDAM
CCCEEEEEEECCCCEEEEEEECCCCHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHH
ASFADFEISAIGITGQVNTHVFVDREGTALLPAILWQDGRAGGEAAGLDARVSAAQKQAW
HHHHCCEEEEEEEEECCCEEEEEECCCCEEHHHHHCCCCCCCCCCCCCCHHHHHHHHHHC
WGAPMPIDASHACSRMAWVARHHPDIWEKTRWVMLPKDYCLLKLTGEATTDPISNIGLVD
CCCCCCCCHHHHHHHHHHHHHCCCCHHHCCEEEEECCCEEEEEEECCCCCCCCCCCCCCC
NTHAYIAEVFDLVPGAADRKVPLVPVCDVVGTVAQGPFAGVPVVSGTMDAWAGLVGAGGA
CCHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHCCCCCCCCEECCCHHHHHHHHCCCCC
KDGSTVYLSGTSEILGISSHDVVPTPGIIVFPEADGIRLHAAPTQSGGDAKVWFSQAGGV
CCCCEEEEECCCCEEECCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCEEEEEECCCCC
SLDQMTELVARTERRAATPLFLPQLQGERAPLWDADLRAAFLGVGRQTNQQDLARAVYEG
CHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHH
VAMSARMALEALQKSAGVVSDTIACGGGGFQSDPWAQIRADILGVELTCLAAKDPGILGA
HHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHEEEEEEEEECCCCCCHHH
AAMAAIGVGHFRAFGEAYDALAVFDRTFTPDPASHTHYNDLFDLYRDAIAVNADLGKRLS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHEEECHHHHHHHH
KLDFSTV
HCCCCCC
>Mature Secondary Structure 
PNRLTLGIDVGTTSVKAGIVDGSGRVVARFAQSYPTLRRGSDIAEQDPDDWVRLISDAM
CCEEEEEEECCCCEEEEEEECCCCHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHH
ASFADFEISAIGITGQVNTHVFVDREGTALLPAILWQDGRAGGEAAGLDARVSAAQKQAW
HHHHCCEEEEEEEEECCCEEEEEECCCCEEHHHHHCCCCCCCCCCCCCCHHHHHHHHHHC
WGAPMPIDASHACSRMAWVARHHPDIWEKTRWVMLPKDYCLLKLTGEATTDPISNIGLVD
CCCCCCCCHHHHHHHHHHHHHCCCCHHHCCEEEEECCCEEEEEEECCCCCCCCCCCCCCC
NTHAYIAEVFDLVPGAADRKVPLVPVCDVVGTVAQGPFAGVPVVSGTMDAWAGLVGAGGA
CCHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHCCCCCCCCEECCCHHHHHHHHCCCCC
KDGSTVYLSGTSEILGISSHDVVPTPGIIVFPEADGIRLHAAPTQSGGDAKVWFSQAGGV
CCCCEEEEECCCCEEECCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCEEEEEECCCCC
SLDQMTELVARTERRAATPLFLPQLQGERAPLWDADLRAAFLGVGRQTNQQDLARAVYEG
CHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHH
VAMSARMALEALQKSAGVVSDTIACGGGGFQSDPWAQIRADILGVELTCLAAKDPGILGA
HHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHEEEEEEEEECCCCCCHHH
AAMAAIGVGHFRAFGEAYDALAVFDRTFTPDPASHTHYNDLFDLYRDAIAVNADLGKRLS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHEEECHHHHHHHH
KLDFSTV
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-xylulose

Specific reaction: ATP + D-xylulose = ADP + D-xylulose 5-phosphate

General reaction: Phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA