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The map label for this gene is ahpF [C]

Identifier: 89054746

GI number: 89054746

Start: 2261824

End: 2262741

Strand: Reverse

Name: ahpF [C]

Synonym: Jann_2255

Alternate gene names: 89054746

Gene position: 2262741-2261824 (Counterclockwise)

Preceding gene: 89054748

Following gene: 89054745

Centisome position: 52.4

GC content: 63.29

Gene sequence:

>918_bases
ATGCAGGATGTTGTGGTTGTTGGCGGCAGTTTCGCTGGATTGACGGCGGCCCTGCAACTTGGCCGCACGGGGCGAGCCGT
CACGATCATTGATGCGCAGGCGCCCCGAAACCGATTGTCGCCCGCGGCACACGGTGTCCCCGGCTTCGACGGCATGGCAC
CGGGAGATATCCTTCAGCGGTTCCGATCAGACGCAACGGCCTACCCGACGGTCTCGGTCGTGACTGAAACAGTGGCCATG
ATCACGGGGGAGGCCGACCGATTTGAAGTATCTCTCGCGTCGGGTGAGACGCTACAGGCGCGCCGCATCCTTTTGACACA
CGGCGTGGTGGACGTGCGTCCAAATCTCCCGGGCGCTCAGGATGCTTGGGGAAAGGTGCTGCTGCACTGCCCCTATTGCC
ATGGCTATGAAGTGCGCGACCAGCCGCTTGCCGTTTTGGCCAACCACGCGATGTCCGGCCATCAGGCGCAGCTTCTGCGG
GCGGACTGGAGCGATGACGTCACGCTGCTGACGGGTGGTCCCGGCACTTTTGACCAGACCGATGTTCAGAGCGGCGATCT
CAAGACCGACCCCCGGACGGTCATTGCGTTAACGCCGTTAAATGACGGCATCTCTGTCACGTTCGACAGTGGCGAAGTGA
CGTGGTTCGCAGCCATGTTCACCGCCCCACTCGTCAGCCTGAGCGGCACCCCCGCAGACAGTCTTGGTTGCGCCGTTCTG
CACGGCCCGCTTGGCCCCTTCATTCACGTGGGACCGATGGGGCAGACGTCGATCCCGGGCGTCTTCGCGGCGGGCGATTG
TGCCCGGGCCGCGCACAACGTCACCTCGGCTATCGGCGACGGATCGATGGCCGGAATTGGCTGTCACCAATCCCTTGTCT
TCCCTGATTTCATCCAACCCATCGAGGCCGCCGCATGA

Upstream 100 bases:

>100_bases
ATGGGTGTGTCCTTCGATATGAACTCAAGTAACAATTGCGGTTGCATATATCCAGTAACTTCGATAGTTACGTTTAAGTC
TTCGAGGGGAGAGGTAAGTC

Downstream 100 bases:

>100_bases
CCGATACCCGTCTACCCGTCACCGTTCTTTCCGGATTTCTAGGGGCCGGTAAGACCACGCTTCTCAACCGTGTTCTCAAC
AACCGCGATGGGCGCCGCGT

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: an alcohol; H2O; NAD [C]

Alternate protein names: Thioredoxin Reductase; FAD-Dependent Pyridine Nucleotide-Disulfide Oxidoreductase; Thioredoxin-Disulfide Reductase; Oxidoreductase; Reductase; Pyridine Nucleotide-Disulphide Oxidoreductase Class II; Pyridine Nucleotide-Disulphide Oxidoreductase; FAD Dependent Oxidoreductase; Thioredoxin Reductase Protein; Pyridine Nucleotide-Disulfide Oxidoreductase; Pyridine Nucleotide-Disulfide Oxidoreductase Domain Protein; Methyltransferase Type; Fad-Dependent Pyridine Nucleotide-Disulfide Oxidoreductase; Alkyl Hydroperoxide Reductase; Pyridine Nucleotide-Disulfide Oxidoreductase Family Protein; NADPH Dependent Thioredoxin Reductase; Oxidoreductase Protein; Methyltransferase; TrxB2 Thioredoxin Reductase; Disulfide Oxidoreductase; Alkyl Hydroperoxide Reductase Large Subunit

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MQDVVVVGGSFAGLTAALQLGRTGRAVTIIDAQAPRNRLSPAAHGVPGFDGMAPGDILQRFRSDATAYPTVSVVTETVAM
ITGEADRFEVSLASGETLQARRILLTHGVVDVRPNLPGAQDAWGKVLLHCPYCHGYEVRDQPLAVLANHAMSGHQAQLLR
ADWSDDVTLLTGGPGTFDQTDVQSGDLKTDPRTVIALTPLNDGISVTFDSGEVTWFAAMFTAPLVSLSGTPADSLGCAVL
HGPLGPFIHVGPMGQTSIPGVFAAGDCARAAHNVTSAIGDGSMAGIGCHQSLVFPDFIQPIEAAA

Sequences:

>Translated_305_residues
MQDVVVVGGSFAGLTAALQLGRTGRAVTIIDAQAPRNRLSPAAHGVPGFDGMAPGDILQRFRSDATAYPTVSVVTETVAM
ITGEADRFEVSLASGETLQARRILLTHGVVDVRPNLPGAQDAWGKVLLHCPYCHGYEVRDQPLAVLANHAMSGHQAQLLR
ADWSDDVTLLTGGPGTFDQTDVQSGDLKTDPRTVIALTPLNDGISVTFDSGEVTWFAAMFTAPLVSLSGTPADSLGCAVL
HGPLGPFIHVGPMGQTSIPGVFAAGDCARAAHNVTSAIGDGSMAGIGCHQSLVFPDFIQPIEAAA
>Mature_305_residues
MQDVVVVGGSFAGLTAALQLGRTGRAVTIIDAQAPRNRLSPAAHGVPGFDGMAPGDILQRFRSDATAYPTVSVVTETVAM
ITGEADRFEVSLASGETLQARRILLTHGVVDVRPNLPGAQDAWGKVLLHCPYCHGYEVRDQPLAVLANHAMSGHQAQLLR
ADWSDDVTLLTGGPGTFDQTDVQSGDLKTDPRTVIALTPLNDGISVTFDSGEVTWFAAMFTAPLVSLSGTPADSLGCAVL
HGPLGPFIHVGPMGQTSIPGVFAAGDCARAAHNVTSAIGDGSMAGIGCHQSLVFPDFIQPIEAAA

Specific function: Serves To Protect The Cell Against DNA Damage By Alkyl Hydroperoxides. It Can Use Either NADH Or NADPH As Electron Donor For Direct Reduction Of Redox Dyes Or Of Alkyl Hydroperoxides When Combined With The Ahpc Protein. [C]

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.6.4.- [C]

Molecular weight: Translated: 31659; Mature: 31659

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDVVVVGGSFAGLTAALQLGRTGRAVTIIDAQAPRNRLSPAAHGVPGFDGMAPGDILQR
CCCEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCHHHCCCCCCCCCCCCCCCHHHHHHH
FRSDATAYPTVSVVTETVAMITGEADRFEVSLASGETLQARRILLTHGVVDVRPNLPGAQ
HHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHEEEEECCEEEECCCCCCCC
DAWGKVLLHCPYCHGYEVRDQPLAVLANHAMSGHQAQLLRADWSDDVTLLTGGPGTFDQT
CCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCCCCCC
DVQSGDLKTDPRTVIALTPLNDGISVTFDSGEVTWFAAMFTAPLVSLSGTPADSLGCAVL
CCCCCCCCCCCCEEEEEEECCCCEEEEECCCCEEEEHHHHHHHHHCCCCCCCHHCCEEEE
HGPLGPFIHVGPMGQTSIPGVFAAGDCARAAHNVTSAIGDGSMAGIGCHQSLVFPDFIQP
ECCCCCEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHH
IEAAA
HHHCC
>Mature Secondary Structure
MQDVVVVGGSFAGLTAALQLGRTGRAVTIIDAQAPRNRLSPAAHGVPGFDGMAPGDILQR
CCCEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCHHHCCCCCCCCCCCCCCCHHHHHHH
FRSDATAYPTVSVVTETVAMITGEADRFEVSLASGETLQARRILLTHGVVDVRPNLPGAQ
HHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHEEEEECCEEEECCCCCCCC
DAWGKVLLHCPYCHGYEVRDQPLAVLANHAMSGHQAQLLRADWSDDVTLLTGGPGTFDQT
CCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCCCCCC
DVQSGDLKTDPRTVIALTPLNDGISVTFDSGEVTWFAAMFTAPLVSLSGTPADSLGCAVL
CCCCCCCCCCCCEEEEEEECCCCEEEEECCCCEEEEHHHHHHHHHCCCCCCCHHCCEEEE
HGPLGPFIHVGPMGQTSIPGVFAAGDCARAAHNVTSAIGDGSMAGIGCHQSLVFPDFIQP
ECCCCCEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHH
IEAAA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ROOH; Proton; NADH [C]

Specific reaction: ROOH + Proton + NADH = an alcohol + H2O + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA