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The map label for this gene is fecD [C]

Identifier: 89054739

GI number: 89054739

Start: 2256500

End: 2257507

Strand: Reverse

Name: fecD [C]

Synonym: Jann_2248

Alternate gene names: 89054739

Gene position: 2257507-2256500 (Counterclockwise)

Preceding gene: 89054740

Following gene: 89054738

Centisome position: 52.28

GC content: 67.96

Gene sequence:

>1008_bases
ATGACCCAGCGCCTGCCGGTCCTGACGTCTCTGGCCCTTGCCGGATTGGTGCTGGCCGTTCTGGCCGGTATCTTCTTCGG
AACGGCAGAAGCGACGTGGAGCGACAGGTGGGCGGCGCTGGTGGGGGGGGCCGACGCGCCCCGCAGCCTGTCGCTGATCA
TATGGGAATGGCGCCTGCCCCGGGTGCTGGCCGTCGCGGCGGTGGGGGCGAGCCTGGCGCTGGCAGGCGTGATGATGCAG
ACGGTGCTGCACAATCCGCTGGCCGATCCCTATCTGATGGGTCTGTCGTCGGGCGCATCTGCGGCGGCTGTGGGCACGAT
CCTGTGGGCACCCGCCTGGGTCGCCTCCACCTTCGGCGTCCCGGTGATCGCCTTTTGCGGGGCCGTCGCCGCCTTCGCCA
TGACGCTGGGTCTGTCGTTTCGGCGCGGCACGATGATGTCACCGCTGGTGGTTATTCTGGCAGGCGTCGCCGTGTCGCTG
ATGTTCCAGTCCCTGACCGCCTTCTTCCTCTACGTGGGCGATCCCCATGCGACGCGCACGGCCCTTGGCTGGCTCATGGG
CACAGCCGCCGGCACCGCGTGGGAGGACCTCTGGCTGCCCCTGATCGCCCTTGCAGGCGTCACCACATATGCGCGCCTCC
ACGCCCAGAATCTCGACGCGCTGCTTTTGGGGGATGAGCGGGCCATGGCGCTCGGCATCCCAGTGCGCAAACTCCGGTTT
GTCGTCTTCGGCGCCGTGGCGCTTCTAGCCGGGCTCTCGGTGGCGAGTGTTGGGATCGTCGGGTTCGTGGGCCTCATCGT
GCCGCATATGGCGCGGCTTCTGGTGGGCGGGCGTCACCGGGTGCTGATCCCACTCAGCCTCGTGCTCGGCGCGCTTGTGC
TGGTCGTGGTGGACCTTCTGTGCCGCATCCTTCTGGCGCCGGAGGAAATGCCCCTGGGGGTGTTGCTTGCTATCTTCGCG
GCCCCGCCATTCATCCTGATCCTGCGGCGGGTGCGCCATGCCTTCTGA

Upstream 100 bases:

>100_bases
GCCCTTCTCGCAGACCGTGCTGGGGATGCAATTCGTCGATGGGCTCGACAATCTGACCGCACAGCTCGCGGCGCTGAACT
GACATGTCCGCGTGCCTGAT

Downstream 100 bases:

>100_bases
TCCAATGATCGAGATTGAGCGCCTGTCGGTGACGCTGGGGGGATCCCCCCGCGTCGATGACTTTTCGCTGACGGTGAAGA
CGGGGGCATTCCATGGCCTG

Product: transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTQRLPVLTSLALAGLVLAVLAGIFFGTAEATWSDRWAALVGGADAPRSLSLIIWEWRLPRVLAVAAVGASLALAGVMMQ
TVLHNPLADPYLMGLSSGASAAAVGTILWAPAWVASTFGVPVIAFCGAVAAFAMTLGLSFRRGTMMSPLVVILAGVAVSL
MFQSLTAFFLYVGDPHATRTALGWLMGTAAGTAWEDLWLPLIALAGVTTYARLHAQNLDALLLGDERAMALGIPVRKLRF
VVFGAVALLAGLSVASVGIVGFVGLIVPHMARLLVGGRHRVLIPLSLVLGALVLVVVDLLCRILLAPEEMPLGVLLAIFA
APPFILILRRVRHAF

Sequences:

>Translated_335_residues
MTQRLPVLTSLALAGLVLAVLAGIFFGTAEATWSDRWAALVGGADAPRSLSLIIWEWRLPRVLAVAAVGASLALAGVMMQ
TVLHNPLADPYLMGLSSGASAAAVGTILWAPAWVASTFGVPVIAFCGAVAAFAMTLGLSFRRGTMMSPLVVILAGVAVSL
MFQSLTAFFLYVGDPHATRTALGWLMGTAAGTAWEDLWLPLIALAGVTTYARLHAQNLDALLLGDERAMALGIPVRKLRF
VVFGAVALLAGLSVASVGIVGFVGLIVPHMARLLVGGRHRVLIPLSLVLGALVLVVVDLLCRILLAPEEMPLGVLLAIFA
APPFILILRRVRHAF
>Mature_334_residues
TQRLPVLTSLALAGLVLAVLAGIFFGTAEATWSDRWAALVGGADAPRSLSLIIWEWRLPRVLAVAAVGASLALAGVMMQT
VLHNPLADPYLMGLSSGASAAAVGTILWAPAWVASTFGVPVIAFCGAVAAFAMTLGLSFRRGTMMSPLVVILAGVAVSLM
FQSLTAFFLYVGDPHATRTALGWLMGTAAGTAWEDLWLPLIALAGVTTYARLHAQNLDALLLGDERAMALGIPVRKLRFV
VFGAVALLAGLSVASVGIVGFVGLIVPHMARLLVGGRHRVLIPLSLVLGALVLVVVDLLCRILLAPEEMPLGVLLAIFAA
PPFILILRRVRHAF

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=298, Percent_Identity=38.9261744966443, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1790741, Length=301, Percent_Identity=36.8770764119601, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1788004, Length=288, Percent_Identity=35.0694444444444, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1786805, Length=279, Percent_Identity=34.0501792114695, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1786347, Length=331, Percent_Identity=30.5135951661631, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1786804, Length=278, Percent_Identity=29.8561151079137, Blast_Score=98, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35121; Mature: 34990

Theoretical pI: Translated: 10.65; Mature: 10.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRLPVLTSLALAGLVLAVLAGIFFGTAEATWSDRWAALVGGADAPRSLSLIIWEWRLP
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCH
RVLAVAAVGASLALAGVMMQTVLHNPLADPYLMGLSSGASAAAVGTILWAPAWVASTFGV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCH
PVIAFCGAVAAFAMTLGLSFRRGTMMSPLVVILAGVAVSLMFQSLTAFFLYVGDPHATRT
HHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
ALGWLMGTAAGTAWEDLWLPLIALAGVTTYARLHAQNLDALLLGDERAMALGIPVRKLRF
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCHHHHHH
VVFGAVALLAGLSVASVGIVGFVGLIVPHMARLLVGGRHRVLIPLSLVLGALVLVVVDLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHH
CRILLAPEEMPLGVLLAIFAAPPFILILRRVRHAF
HHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TQRLPVLTSLALAGLVLAVLAGIFFGTAEATWSDRWAALVGGADAPRSLSLIIWEWRLP
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCH
RVLAVAAVGASLALAGVMMQTVLHNPLADPYLMGLSSGASAAAVGTILWAPAWVASTFGV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCH
PVIAFCGAVAAFAMTLGLSFRRGTMMSPLVVILAGVAVSLMFQSLTAFFLYVGDPHATRT
HHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
ALGWLMGTAAGTAWEDLWLPLIALAGVTTYARLHAQNLDALLLGDERAMALGIPVRKLRF
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCHHHHHH
VVFGAVALLAGLSVASVGIVGFVGLIVPHMARLLVGGRHRVLIPLSLVLGALVLVVVDLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHH
CRILLAPEEMPLGVLLAIFAAPPFILILRRVRHAF
HHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]