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The map label for this gene is fadB1 [H]

Identifier: 89054645

GI number: 89054645

Start: 2162565

End: 2163341

Strand: Direct

Name: fadB1 [H]

Synonym: Jann_2154

Alternate gene names: 89054645

Gene position: 2162565-2163341 (Clockwise)

Preceding gene: 89054644

Following gene: 89054646

Centisome position: 50.08

GC content: 65.77

Gene sequence:

>777_bases
ATGAATTATGAGACCATCACTGCCGTCACCCGCGACGGCGCGGCTGTCATCACCCTCAACCGTCCCGATGTGATGAACGC
GCTCAACACGCAGATGCGCGCCGAGATCACCCACGCGGTTGGCGTTGCGGCGCAGGAGGCGCGGGTTGTGGTGCTGACGG
GCACGGGCCGCGCGTTCTGCTCGGGCCAGGATCTGGGGGACCGCGCCAATGCGGGCAACCTGAACCTGGAGCGGACGCTG
CGGGATGAGTACATCCCCATGCTCAACGCCATCACCGACTGCCCCGTCCCGGTCATTGCCGCCGTCAATGGCACGGCTGC
GGGGGCGGGGGCCAACCTCGCGCTGGTCTGCGATATCGTCATCGCCGCCGAGAGCGCGTCGTTCATCCAGGCCTTCTCTC
GTATCGGGCTGATCCCCGATGCGGGGGGCACGTGGGCGTTGCCGCGCACCATCGGGCTTCAGCGTGCCATGGGGGCGGCC
TTGTTCGCCGAGAAGATCACCGCCGCCCAGGCCGCTGAGTGGGGGATGATCTGGGAGATGGCCTCTGACGCGGAGTTTGA
GGCCACATGGATGGCCCGCGCCACCCATCTTGCCACGGGTCCGACGGAGGCGTTCAAGCGGATCAAGCAGGTGATGCGAG
CAAGCTCTGGCAACTCCCTCGAAGAGCAGCTTTTGCTGGAGGGTCAGTTGCAGGGCCAATGCGGCAAAAGCCGGGATTTC
AAAGAGGGTGTCGTGGCCTTTCTGGAAAAGCGGCCCGCGGTGTTCGAGGGGCGTTAG

Upstream 100 bases:

>100_bases
ATCCTGTCTGATGAGCCAAAGGCGTGACTGACGCAGCGTTTTGGCTTTTCTGAACCGAACGGTTTGATATGGTCCCCCAA
ACCCCAGGGAGGCTACACCC

Downstream 100 bases:

>100_bases
ACTTTAGGTTGCAAGGTTGCAAGGTTGCAACCAGGGGGTAAGCCTCTGAAAACTATGTAAAAATACTATCTTATTAACCT
TTTAGTATCCCATATGGCGG

Product: short chain enoyl-CoA hydratase / enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MNYETITAVTRDGAAVITLNRPDVMNALNTQMRAEITHAVGVAAQEARVVVLTGTGRAFCSGQDLGDRANAGNLNLERTL
RDEYIPMLNAITDCPVPVIAAVNGTAAGAGANLALVCDIVIAAESASFIQAFSRIGLIPDAGGTWALPRTIGLQRAMGAA
LFAEKITAAQAAEWGMIWEMASDAEFEATWMARATHLATGPTEAFKRIKQVMRASSGNSLEEQLLLEGQLQGQCGKSRDF
KEGVVAFLEKRPAVFEGR

Sequences:

>Translated_258_residues
MNYETITAVTRDGAAVITLNRPDVMNALNTQMRAEITHAVGVAAQEARVVVLTGTGRAFCSGQDLGDRANAGNLNLERTL
RDEYIPMLNAITDCPVPVIAAVNGTAAGAGANLALVCDIVIAAESASFIQAFSRIGLIPDAGGTWALPRTIGLQRAMGAA
LFAEKITAAQAAEWGMIWEMASDAEFEATWMARATHLATGPTEAFKRIKQVMRASSGNSLEEQLLLEGQLQGQCGKSRDF
KEGVVAFLEKRPAVFEGR
>Mature_258_residues
MNYETITAVTRDGAAVITLNRPDVMNALNTQMRAEITHAVGVAAQEARVVVLTGTGRAFCSGQDLGDRANAGNLNLERTL
RDEYIPMLNAITDCPVPVIAAVNGTAAGAGANLALVCDIVIAAESASFIQAFSRIGLIPDAGGTWALPRTIGLQRAMGAA
LFAEKITAAQAAEWGMIWEMASDAEFEATWMARATHLATGPTEAFKRIKQVMRASSGNSLEEQLLLEGQLQGQCGKSRDF
KEGVVAFLEKRPAVFEGR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=260, Percent_Identity=33.0769230769231, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI45643119, Length=259, Percent_Identity=29.3436293436293, Blast_Score=118, Evalue=5e-27,
Organism=Homo sapiens, GI260275230, Length=259, Percent_Identity=29.3436293436293, Blast_Score=118, Evalue=5e-27,
Organism=Homo sapiens, GI260274832, Length=259, Percent_Identity=29.3436293436293, Blast_Score=118, Evalue=5e-27,
Organism=Homo sapiens, GI25453481, Length=229, Percent_Identity=27.0742358078603, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI51538573, Length=229, Percent_Identity=27.0742358078603, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4757966, Length=229, Percent_Identity=27.0742358078603, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI51538581, Length=229, Percent_Identity=27.0742358078603, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4757968, Length=232, Percent_Identity=27.1551724137931, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI49355787, Length=232, Percent_Identity=27.1551724137931, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI31542718, Length=248, Percent_Identity=27.4193548387097, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI70995211, Length=182, Percent_Identity=34.0659340659341, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI221136756, Length=229, Percent_Identity=27.5109170305677, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI221136753, Length=229, Percent_Identity=27.5109170305677, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI221307494, Length=229, Percent_Identity=27.5109170305677, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI4502327, Length=253, Percent_Identity=29.2490118577075, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI116235487, Length=205, Percent_Identity=27.3170731707317, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI37594469, Length=152, Percent_Identity=33.5526315789474, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI37594471, Length=152, Percent_Identity=33.5526315789474, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI1787660, Length=260, Percent_Identity=45.3846153846154, Blast_Score=194, Evalue=6e-51,
Organism=Escherichia coli, GI1787659, Length=251, Percent_Identity=37.0517928286853, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI221142681, Length=258, Percent_Identity=31.0077519379845, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788597, Length=261, Percent_Identity=28.3524904214559, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082183, Length=270, Percent_Identity=26.2962962962963, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790281, Length=170, Percent_Identity=27.6470588235294, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788682, Length=210, Percent_Identity=27.6190476190476, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=252, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17554946, Length=250, Percent_Identity=32.8, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17535521, Length=255, Percent_Identity=28.6274509803922, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17549921, Length=174, Percent_Identity=33.9080459770115, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17560910, Length=188, Percent_Identity=28.7234042553192, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17540306, Length=218, Percent_Identity=29.8165137614679, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17540714, Length=246, Percent_Identity=28.0487804878049, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17534483, Length=180, Percent_Identity=30.5555555555556, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17536985, Length=261, Percent_Identity=23.3716475095785, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320241, Length=193, Percent_Identity=31.6062176165803, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI20129971, Length=259, Percent_Identity=31.6602316602317, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24653477, Length=259, Percent_Identity=31.6602316602317, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24654903, Length=214, Percent_Identity=24.2990654205607, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24653139, Length=262, Percent_Identity=32.824427480916, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19920382, Length=250, Percent_Identity=29.6, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28571730, Length=160, Percent_Identity=31.875, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI28571729, Length=160, Percent_Identity=31.875, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI19922422, Length=251, Percent_Identity=25.0996015936255, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27425; Mature: 27425

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYETITAVTRDGAAVITLNRPDVMNALNTQMRAEITHAVGVAAQEARVVVLTGTGRAFC
CCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCEECCCEEEEEECCCCEEE
SGQDLGDRANAGNLNLERTLRDEYIPMLNAITDCPVPVIAAVNGTAAGAGANLALVCDIV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEEEEE
IAAESASFIQAFSRIGLIPDAGGTWALPRTIGLQRAMGAALFAEKITAAQAAEWGMIWEM
HCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
ASDAEFEATWMARATHLATGPTEAFKRIKQVMRASSGNSLEEQLLLEGQLQGQCGKSRDF
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCH
KEGVVAFLEKRPAVFEGR
HHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNYETITAVTRDGAAVITLNRPDVMNALNTQMRAEITHAVGVAAQEARVVVLTGTGRAFC
CCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCEECCCEEEEEECCCCEEE
SGQDLGDRANAGNLNLERTLRDEYIPMLNAITDCPVPVIAAVNGTAAGAGANLALVCDIV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEEEEE
IAAESASFIQAFSRIGLIPDAGGTWALPRTIGLQRAMGAALFAEKITAAQAAEWGMIWEM
HCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
ASDAEFEATWMARATHLATGPTEAFKRIKQVMRASSGNSLEEQLLLEGQLQGQCGKSRDF
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCH
KEGVVAFLEKRPAVFEGR
HHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1743516 [H]