BacMap

Definition	Jannaschia sp. CCS1 chromosome, complete genome.
Accession	NC_007802
Length	4,317,977

Click here to switch to the map view.

The map label for this gene is ppi [H]

Identifier: 89054409

GI number: 89054409

Start: 1906195

End: 1906821

Strand: Direct

Name: ppi [H]

Synonym: Jann_1918

Alternate gene names: 89054409

Gene position: 1906195-1906821 (Clockwise)

Preceding gene: 89054408

Following gene: 89054410

Centisome position: 44.15

GC content: 63.64

Gene sequence:

>627_bases
ATGCGTAAGGCGACAGCCCCTTGGGCGGCCTTCGGGCCGCTCCTCGCTGCGCTCCTCGCCGCCGCTCCGATTGGGGCGAC
GGGGATCGAGATCGACGTTGCCGGAGAGGCCGAGGGTACGATTGTCATCGACCTGTTCGAGGATGTCGCTCCGCTGCACG
TGGAGCGGATCACAACGCTGGCCACGGAAGGCGCGTATGACGACATTGTCTTCCACCGGGTGATTGACGGCTTCATGGCA
CAGACCGGCGACGTTGAGTTTGGCGGTTTGGGTCAGGACATGCGCTATGCGGGGCGGGGCGGGTCGACCTATGACGATCT
GCCAGCTGAATTCTCGGACCTCTCGTTCGAGCGCGGAACATTGGGCATGGCACGGTCCCAGCGACCGGATTCGGCCAACA
GCCAGTTTTTCATCGTGTTCGAGGCGGCCTCGCACCTGAATGGCCAATATACCGTGTTCGGACAGGTGGTGGACGGCATG
GATGTGGTCGACATGATCCGCCGGGGCCGGGGCCGCAATGGGGCCGTGACCGGAGAGCCGGACCGCATGACCGCCGTGCG
GGTGCTGGATTTTGACCCGGAGCCTCCTGAACCTGAAGAAGAAGACGCAGAGGAGGCGTCTGAATAG

Upstream 100 bases:

>100_bases
TATGGGCGGGTCACGTCGGGTATGGAGCATGTGGATGCGATCACGCGGGGCGAGCCGCCTGCGGACCCCGATGTGATGAT
CTCCGTGAAGGTCGCCGCCG

Downstream 100 bases:

>100_bases
GATTGCGCCGGCTTCGCCGTCGCCAGGGAAACGCGCGGCCTCAAGCCCCGTTGGGGCCATCGGCCGCGCGTGCTGCCGCG
ATGACCTGGCCAATGGCGCG

Product: cyclophilin type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MRKATAPWAAFGPLLAALLAAAPIGATGIEIDVAGEAEGTIVIDLFEDVAPLHVERITTLATEGAYDDIVFHRVIDGFMA
QTGDVEFGGLGQDMRYAGRGGSTYDDLPAEFSDLSFERGTLGMARSQRPDSANSQFFIVFEAASHLNGQYTVFGQVVDGM
DVVDMIRRGRGRNGAVTGEPDRMTAVRVLDFDPEPPEPEEEDAEEASE

Sequences:

>Translated_208_residues
MRKATAPWAAFGPLLAALLAAAPIGATGIEIDVAGEAEGTIVIDLFEDVAPLHVERITTLATEGAYDDIVFHRVIDGFMA
QTGDVEFGGLGQDMRYAGRGGSTYDDLPAEFSDLSFERGTLGMARSQRPDSANSQFFIVFEAASHLNGQYTVFGQVVDGM
DVVDMIRRGRGRNGAVTGEPDRMTAVRVLDFDPEPPEPEEEDAEEASE
>Mature_208_residues
MRKATAPWAAFGPLLAALLAAAPIGATGIEIDVAGEAEGTIVIDLFEDVAPLHVERITTLATEGAYDDIVFHRVIDGFMA
QTGDVEFGGLGQDMRYAGRGGSTYDDLPAEFSDLSFERGTLGMARSQRPDSANSQFFIVFEAASHLNGQYTVFGQVVDGM
DVVDMIRRGRGRNGAVTGEPDRMTAVRVLDFDPEPPEPEEEDAEEASE

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI19557636, Length=130, Percent_Identity=34.6153846153846, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI10863927, Length=158, Percent_Identity=35.4430379746835, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI4505991, Length=132, Percent_Identity=41.6666666666667, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI150418007, Length=171, Percent_Identity=33.9181286549708, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI5031987, Length=142, Percent_Identity=36.6197183098592, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI7706339, Length=129, Percent_Identity=34.8837209302326, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI169163387, Length=155, Percent_Identity=31.6129032258064, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI310110104, Length=150, Percent_Identity=34.6666666666667, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI42560244, Length=154, Percent_Identity=35.0649350649351, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4826932, Length=175, Percent_Identity=32, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI169164185, Length=155, Percent_Identity=31.6129032258064, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI169163623, Length=155, Percent_Identity=31.6129032258064, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI310129267, Length=153, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI310120620, Length=153, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI169214050, Length=180, Percent_Identity=32.7777777777778, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI22547212, Length=166, Percent_Identity=32.5301204819277, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI7657473, Length=166, Percent_Identity=32.5301204819277, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI22547215, Length=166, Percent_Identity=32.5301204819277, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI64276486, Length=131, Percent_Identity=37.4045801526718, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI45439316, Length=156, Percent_Identity=31.4102564102564, Blast_Score=67, Evalue=9e-12,
Organism=Homo sapiens, GI24308049, Length=130, Percent_Identity=37.6923076923077, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1786736, Length=147, Percent_Identity=41.4965986394558, Blast_Score=88, Evalue=3e-19,
Organism=Escherichia coli, GI1789763, Length=155, Percent_Identity=34.8387096774194, Blast_Score=74, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17551284, Length=148, Percent_Identity=36.4864864864865, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17551282, Length=148, Percent_Identity=36.4864864864865, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71980594, Length=128, Percent_Identity=38.28125, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71980590, Length=128, Percent_Identity=38.28125, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17539496, Length=131, Percent_Identity=36.6412213740458, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17506311, Length=143, Percent_Identity=37.0629370629371, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17539498, Length=173, Percent_Identity=33.5260115606936, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17552784, Length=154, Percent_Identity=35.0649350649351, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17566266, Length=169, Percent_Identity=31.9526627218935, Blast_Score=71, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17559074, Length=175, Percent_Identity=33.1428571428571, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17565860, Length=163, Percent_Identity=33.7423312883436, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17552780, Length=141, Percent_Identity=36.8794326241135, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17532641, Length=136, Percent_Identity=33.0882352941176, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17552782, Length=157, Percent_Identity=31.2101910828025, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17532643, Length=147, Percent_Identity=35.3741496598639, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322492, Length=170, Percent_Identity=34.1176470588235, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321848, Length=147, Percent_Identity=40.8163265306122, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320359, Length=170, Percent_Identity=31.7647058823529, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323246, Length=159, Percent_Identity=32.0754716981132, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323562, Length=152, Percent_Identity=33.5526315789474, Blast_Score=67, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19922376, Length=130, Percent_Identity=33.0769230769231, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24652460, Length=133, Percent_Identity=36.0902255639098, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI17986117, Length=128, Percent_Identity=36.71875, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI20130249, Length=142, Percent_Identity=35.9154929577465, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650807, Length=151, Percent_Identity=34.4370860927152, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24661775, Length=162, Percent_Identity=30.8641975308642, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21355237, Length=162, Percent_Identity=30.8641975308642, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24661771, Length=162, Percent_Identity=30.8641975308642, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24664125, Length=147, Percent_Identity=36.0544217687075, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21357783, Length=147, Percent_Identity=36.0544217687075, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI17136360, Length=167, Percent_Identity=33.5329341317365, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: 780 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 22346; Mature: 22346

Theoretical pI: Translated: 3.97; Mature: 3.97

Prosite motif: PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKATAPWAAFGPLLAALLAAAPIGATGIEIDVAGEAEGTIVIDLFEDVAPLHVERITTL
CCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHH
ATEGAYDDIVFHRVIDGFMAQTGDVEFGGLGQDMRYAGRGGSTYDDLPAEFSDLSFERGT
HCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCHHHCCCCCCC
LGMARSQRPDSANSQFFIVFEAASHLNGQYTVFGQVVDGMDVVDMIRRGRGRNGAVTGEP
CCCCCCCCCCCCCCCEEEEEEECHHCCCCEEEEEEHHCCHHHHHHHHCCCCCCCCCCCCC
DRMTAVRVLDFDPEPPEPEEEDAEEASE
CCEEEEEEEECCCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MRKATAPWAAFGPLLAALLAAAPIGATGIEIDVAGEAEGTIVIDLFEDVAPLHVERITTL
CCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHH
ATEGAYDDIVFHRVIDGFMAQTGDVEFGGLGQDMRYAGRGGSTYDDLPAEFSDLSFERGT
HCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCHHHCCCCCCC
LGMARSQRPDSANSQFFIVFEAASHLNGQYTVFGQVVDGMDVVDMIRRGRGRNGAVTGEP
CCCCCCCCCCCCCCCEEEEEEECHHCCCCEEEEEEHHCCHHHHHHHHCCCCCCCCCCCCC
DRMTAVRVLDFDPEPPEPEEEDAEEASE
CCEEEEEEEECCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA