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The map label for this gene is siaT [H]

Identifier: 89053941

GI number: 89053941

Start: 1419203

End: 1420465

Strand: Direct

Name: siaT [H]

Synonym: Jann_1450

Alternate gene names: 89053941

Gene position: 1419203-1420465 (Clockwise)

Preceding gene: 89053940

Following gene: 89053943

Centisome position: 32.87

GC content: 61.76

Gene sequence:

>1263_bases
ATGACGCCCGTCATCTTCCTGACCAAGCTGCTGCTGGCGGTTCCGGTTGCCATCGTCCTGTCGTTGACCGCGATCTGGTA
CATCTGGGAGAGTGACAACACGATCCTCTATGAGAGCTTCGCGCAGCGGATGTTTTCCGGGATCGAAAGCTATGGCTTGC
TCGCCATCCCGCTGTTCATGCTGACCGGAGAGCTGATGAACGAGGGCGGCATGACCCGCCGTCTGATCAACGCGGCGCGC
GTCTTCGTGGGCGGGTTTCGCGGGGGGCTGGCCTACATCAATCTGTTGGCCAACATGTTCATGGCCGCCATCGTCGGGTC
CGCTGCCGCCCAGATCGCGGTGATGTCGCGCGCCATGGTCCCCGCGATGGAAGAAGAAGGCTACGACCGCGGTTTCGCGG
CGGCGACTACGGCGGCCGGTGGCCTGCTGGCCCCGGTGATCCCGCCTTCAATGCTGTTCGTGATCTACGGCGTCTTGGCA
CAGATCCCCATCGGCAACATGTTCCTGGCGGGCATCATCCCGGGCCTGATCCTATCGGTCTGCTTCGCGCTGGTGATCGC
GCTGATCGGGCTGCGACAGCAGTTCCCCAAGGGGGAGTGGATGGCCGCGCGGGACGCCTGGAACGCGGTGCTTTATGCGC
TGCCCGCGATGCTGATCCCGGCGGCGATCATCGGGGGCATCATCGGCGGCATCGCGACGCCAACGGAATCCGCTGCCGTG
GCGAGCGTTGTGGCATTTCTGCTGGGATGGCTGCTCTATCGGGAATTGAACCCAACGAAACTGTTTGAAATGTTCAAGCG
CACCGCGCTGAATGCGTCGCTGATCATCTTCATGATCGCGGCCGCAAACGTCTTTGGCTGGGTCATTATCTATGAGGCGC
TGCCGCAGCGGCTGGCCGAATTTATCACCACGATCACCCAGAACCCGTTCGTGTTTTTGCTGATTGTAAACCTCGTGTTG
CTGTTTGTGGGCATGCTGATCGACGGCATCGCTGCGATCATTCTGGTGACGCCGATCCTGTTGCCGATTGCCATCGACAG
CTACGGGATCTCTCCCTACCAGTTCGGGGTCGTGATCTCGCTGAACCTGGTGCTTGGCCTGCTGACCCCACCGGTGGGCG
TGGGCCTCTACATCGCGTCGGCCATGTCCGAGACGCCGACGGGCCGGATCTTGAAGGCGCTTTGGCCGTTCCTGCTGGCG
GTCACGGCAGTGCTGATCCTGCTGAGCTACGCGCCCGCGCTGTCGACGATGTTGATAGATTGA

Upstream 100 bases:

>100_bases
GGCTGGTCATGCCCCTGTTTTCCTGTGGCGTCTTCCTGCACGCGCTGGCCCATCTGATCGACCTCACCCCGCCCGAGGCA
CGGCTGTCGGAGGTGCAGGC

Downstream 100 bases:

>100_bases
GAGTGTGTTGCGCGACCACGTTTCGCGCCACCTGAGCGCGGGTCAGGCGAAGCGGATGGGATCGTGAAGTTGCCGGATTG
CGGCAATCGCGGACATCGCG

Product: TRAP C4-dicarboxylate transport system permease DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MTPVIFLTKLLLAVPVAIVLSLTAIWYIWESDNTILYESFAQRMFSGIESYGLLAIPLFMLTGELMNEGGMTRRLINAAR
VFVGGFRGGLAYINLLANMFMAAIVGSAAAQIAVMSRAMVPAMEEEGYDRGFAAATTAAGGLLAPVIPPSMLFVIYGVLA
QIPIGNMFLAGIIPGLILSVCFALVIALIGLRQQFPKGEWMAARDAWNAVLYALPAMLIPAAIIGGIIGGIATPTESAAV
ASVVAFLLGWLLYRELNPTKLFEMFKRTALNASLIIFMIAAANVFGWVIIYEALPQRLAEFITTITQNPFVFLLIVNLVL
LFVGMLIDGIAAIILVTPILLPIAIDSYGISPYQFGVVISLNLVLGLLTPPVGVGLYIASAMSETPTGRILKALWPFLLA
VTAVLILLSYAPALSTMLID

Sequences:

>Translated_420_residues
MTPVIFLTKLLLAVPVAIVLSLTAIWYIWESDNTILYESFAQRMFSGIESYGLLAIPLFMLTGELMNEGGMTRRLINAAR
VFVGGFRGGLAYINLLANMFMAAIVGSAAAQIAVMSRAMVPAMEEEGYDRGFAAATTAAGGLLAPVIPPSMLFVIYGVLA
QIPIGNMFLAGIIPGLILSVCFALVIALIGLRQQFPKGEWMAARDAWNAVLYALPAMLIPAAIIGGIIGGIATPTESAAV
ASVVAFLLGWLLYRELNPTKLFEMFKRTALNASLIIFMIAAANVFGWVIIYEALPQRLAEFITTITQNPFVFLLIVNLVL
LFVGMLIDGIAAIILVTPILLPIAIDSYGISPYQFGVVISLNLVLGLLTPPVGVGLYIASAMSETPTGRILKALWPFLLA
VTAVLILLSYAPALSTMLID
>Mature_419_residues
TPVIFLTKLLLAVPVAIVLSLTAIWYIWESDNTILYESFAQRMFSGIESYGLLAIPLFMLTGELMNEGGMTRRLINAARV
FVGGFRGGLAYINLLANMFMAAIVGSAAAQIAVMSRAMVPAMEEEGYDRGFAAATTAAGGLLAPVIPPSMLFVIYGVLAQ
IPIGNMFLAGIIPGLILSVCFALVIALIGLRQQFPKGEWMAARDAWNAVLYALPAMLIPAAIIGGIIGGIATPTESAAVA
SVVAFLLGWLLYRELNPTKLFEMFKRTALNASLIIFMIAAANVFGWVIIYEALPQRLAEFITTITQNPFVFLLIVNLVLL
FVGMLIDGIAAIILVTPILLPIAIDSYGISPYQFGVVISLNLVLGLLTPPVGVGLYIASAMSETPTGRILKALWPFLLAV
TAVLILLSYAPALSTMLID

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=356, Percent_Identity=33.4269662921348, Blast_Score=195, Evalue=5e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 44951; Mature: 44820

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS01189 RIBOSOMAL_S12E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPVIFLTKLLLAVPVAIVLSLTAIWYIWESDNTILYESFAQRMFSGIESYGLLAIPLFM
CCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEHHHHHHHHHHHHHHHCCHHHHHHHH
LTGELMNEGGMTRRLINAARVFVGGFRGGLAYINLLANMFMAAIVGSAAAQIAVMSRAMV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PAMEEEGYDRGFAAATTAAGGLLAPVIPPSMLFVIYGVLAQIPIGNMFLAGIIPGLILSV
CHHHHCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
CFALVIALIGLRQQFPKGEWMAARDAWNAVLYALPAMLIPAAIIGGIIGGIATPTESAAV
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ASVVAFLLGWLLYRELNPTKLFEMFKRTALNASLIIFMIAAANVFGWVIIYEALPQRLAE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FITTITQNPFVFLLIVNLVLLFVGMLIDGIAAIILVTPILLPIAIDSYGISPYQFGVVIS
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LNLVLGLLTPPVGVGLYIASAMSETPTGRILKALWPFLLAVTAVLILLSYAPALSTMLID
HHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPVIFLTKLLLAVPVAIVLSLTAIWYIWESDNTILYESFAQRMFSGIESYGLLAIPLFM
CHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEHHHHHHHHHHHHHHHCCHHHHHHHH
LTGELMNEGGMTRRLINAARVFVGGFRGGLAYINLLANMFMAAIVGSAAAQIAVMSRAMV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PAMEEEGYDRGFAAATTAAGGLLAPVIPPSMLFVIYGVLAQIPIGNMFLAGIIPGLILSV
CHHHHCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
CFALVIALIGLRQQFPKGEWMAARDAWNAVLYALPAMLIPAAIIGGIIGGIATPTESAAV
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ASVVAFLLGWLLYRELNPTKLFEMFKRTALNASLIIFMIAAANVFGWVIIYEALPQRLAE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FITTITQNPFVFLLIVNLVLLFVGMLIDGIAAIILVTPILLPIAIDSYGISPYQFGVVIS
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LNLVLGLLTPPVGVGLYIASAMSETPTGRILKALWPFLLAVTAVLILLSYAPALSTMLID
HHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]