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The map label for this gene is mcpA [H]

Identifier: 89053870

GI number: 89053870

Start: 1347982

End: 1349340

Strand: Reverse

Name: mcpA [H]

Synonym: Jann_1379

Alternate gene names: 89053870

Gene position: 1349340-1347982 (Counterclockwise)

Preceding gene: 89053877

Following gene: 89053869

Centisome position: 31.25

GC content: 59.16

Gene sequence:

>1359_bases
ATGTTTTGGAAGGCCAAGCACCCCGTCGAACCGAGTAAGGTCGACGACGTCACAGAGACATTTATCGCCATCATCGACCG
CACGCAGGCCACCATTCAATTTGAACTGGACGGGACAATCATCGACGCCAATGCCAATCTGCTGCGCGCCACGGGCTACA
CACTGGACGAGCTTGTCGGCAAACACCATTCAATGTTCGTCGATCCCGGTTTCGCAAAGACCCCCGCATATGCACAGTTC
TGGGAGCGTCTGGGGCAGGGAGAGATTCTCGATGACATCTACCCCCGGATCGCAAAAGACGGATCGACTGTCTGGATGCA
GGCCGCATACGCCCCGGTATTCGCAGCCGATGGCACGCCGACGCGCGTGATCAAGATTGCCACGGACATCACCGATCGTC
AGAGCGATATTGCCGAGATCGCGGTGGGTCTGGAAGAGATGAGTAATAAGACCCTCTCGCACCGGATCGCCGTCTCCAAA
CACAACGATCTGGCGAAACTTGGGACAGCATTCAATCTGGCCCAGGAACAGTTGAGTTCGGCCCTGGACATTGCCAAAGA
CGTCTCGTCGGGGGTGGAACAGACTGCGGATGACCTCAGCCAGGCCTCCGGTGCACTTGCGCAACGCACGGAAACGCAAG
CCGCCACCCTGGAAGAGACAGCCGCCGCCCTGGAAGAGATGTCGGCAACGGTACAGGCCACGGTCGGCAGCACCAAGGAT
GTGGAGCGGGCCGCGAAGGCGGCGACCGCCACCGCCGAGACCGGCGGCAAAGTCGTGGATAATGCGGTCAACGCCATGTC
GCTCATCGAGAAATCGTCCCATGACATCGCGCGCATTATCTCGGTGATGGAGGAGATTGCCTTTCAAACTAATCTCCTCG
CGTTGAATGCCGGCGTGGAAGCCGCGCGCGCCGGCGACGCGGGACGCGGGTTTGCGGTCGTCGCGTCAGAGGTGCGGGCT
CTGGCGCAACGGGCGTCAGAATCCGCCGGTGAAATCAAGACGCTGATCTCCGGGAGTTCCGAGCATGTGGCCAGTGGTGT
CGAACTGGTCGGGCGTGCTGGGAAAGAACTGTCCAACATCATTTCAAGCGTCTCCCAGATCTCGTCCAATATCAGCGATA
TTGCCAACACGACGACCGAACAGGCCACCGCTCTGACAGAGATCAACACCGGCCTGTCGCAACTGGATCAGGTGACCCAG
CAAAACACGGCCATGGTCGCTGAAACCTCGGCGGCGGGGCAGACGTTGGCCAAGGATGCCAAACATTTGACAGAGGTTCT
ATCGGATTTTCAGACACATATCGACGGCTACGCGGCACCACAGATCTCCATGGACAGCCCCGAAAGGCTAAGCGCATAG

Upstream 100 bases:

>100_bases
ATGGATCAAAAATGAAGCACGGAGCCCCCATCCGTTCACGATTTTTAAGGACCTTTTGGATCAGATGCGCTCAACAGCAA
TAACCGCCAGGAGCTCTTGG

Downstream 100 bases:

>100_bases
GATAACCCAAAGCGCGTCGCATGCCTCCCCTGACCGGGGCCCGGCCTGATCGCGTTGAACGATGTCAGTGAACCGCACAT
CGCTGCGTTCTCCAACGCCT

Product: methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MFWKAKHPVEPSKVDDVTETFIAIIDRTQATIQFELDGTIIDANANLLRATGYTLDELVGKHHSMFVDPGFAKTPAYAQF
WERLGQGEILDDIYPRIAKDGSTVWMQAAYAPVFAADGTPTRVIKIATDITDRQSDIAEIAVGLEEMSNKTLSHRIAVSK
HNDLAKLGTAFNLAQEQLSSALDIAKDVSSGVEQTADDLSQASGALAQRTETQAATLEETAAALEEMSATVQATVGSTKD
VERAAKAATATAETGGKVVDNAVNAMSLIEKSSHDIARIISVMEEIAFQTNLLALNAGVEAARAGDAGRGFAVVASEVRA
LAQRASESAGEIKTLISGSSEHVASGVELVGRAGKELSNIISSVSQISSNISDIANTTTEQATALTEINTGLSQLDQVTQ
QNTAMVAETSAAGQTLAKDAKHLTEVLSDFQTHIDGYAAPQISMDSPERLSA

Sequences:

>Translated_452_residues
MFWKAKHPVEPSKVDDVTETFIAIIDRTQATIQFELDGTIIDANANLLRATGYTLDELVGKHHSMFVDPGFAKTPAYAQF
WERLGQGEILDDIYPRIAKDGSTVWMQAAYAPVFAADGTPTRVIKIATDITDRQSDIAEIAVGLEEMSNKTLSHRIAVSK
HNDLAKLGTAFNLAQEQLSSALDIAKDVSSGVEQTADDLSQASGALAQRTETQAATLEETAAALEEMSATVQATVGSTKD
VERAAKAATATAETGGKVVDNAVNAMSLIEKSSHDIARIISVMEEIAFQTNLLALNAGVEAARAGDAGRGFAVVASEVRA
LAQRASESAGEIKTLISGSSEHVASGVELVGRAGKELSNIISSVSQISSNISDIANTTTEQATALTEINTGLSQLDQVTQ
QNTAMVAETSAAGQTLAKDAKHLTEVLSDFQTHIDGYAAPQISMDSPERLSA
>Mature_452_residues
MFWKAKHPVEPSKVDDVTETFIAIIDRTQATIQFELDGTIIDANANLLRATGYTLDELVGKHHSMFVDPGFAKTPAYAQF
WERLGQGEILDDIYPRIAKDGSTVWMQAAYAPVFAADGTPTRVIKIATDITDRQSDIAEIAVGLEEMSNKTLSHRIAVSK
HNDLAKLGTAFNLAQEQLSSALDIAKDVSSGVEQTADDLSQASGALAQRTETQAATLEETAAALEEMSATVQATVGSTKD
VERAAKAATATAETGGKVVDNAVNAMSLIEKSSHDIARIISVMEEIAFQTNLLALNAGVEAARAGDAGRGFAVVASEVRA
LAQRASESAGEIKTLISGSSEHVASGVELVGRAGKELSNIISSVSQISSNISDIANTTTEQATALTEINTGLSQLDQVTQ
QNTAMVAETSAAGQTLAKDAKHLTEVLSDFQTHIDGYAAPQISMDSPERLSA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=295, Percent_Identity=38.6440677966102, Blast_Score=188, Evalue=5e-49,
Organism=Escherichia coli, GI2367378, Length=282, Percent_Identity=41.4893617021277, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI1787690, Length=273, Percent_Identity=38.8278388278388, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1788194, Length=282, Percent_Identity=39.7163120567376, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1789453, Length=246, Percent_Identity=33.3333333333333, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 47750; Mature: 47750

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFWKAKHPVEPSKVDDVTETFIAIIDRTQATIQFELDGTIIDANANLLRATGYTLDELVG
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCEEEECCCCEEEECCCCHHHHHC
KHHSMFVDPGFAKTPAYAQFWERLGQGEILDDIYPRIAKDGSTVWMQAAYAPVFAADGTP
CCCCEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEHHHCCCEEECCCCC
TRVIKIATDITDRQSDIAEIAVGLEEMSNKTLSHRIAVSKHNDLAKLGTAFNLAQEQLSS
CEEEEEECCCCCHHHHHHHHHHHHHHHHCHHHHHHEEECCCCCHHHHHHHHHHHHHHHHH
ALDIAKDVSSGVEQTADDLSQASGALAQRTETQAATLEETAAALEEMSATVQATVGSTKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
VERAAKAATATAETGGKVVDNAVNAMSLIEKSSHDIARIISVMEEIAFQTNLLALNAGVE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCH
AARAGDAGRGFAVVASEVRALAQRASESAGEIKTLISGSSEHVASGVELVGRAGKELSNI
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ISSVSQISSNISDIANTTTEQATALTEINTGLSQLDQVTQQNTAMVAETSAAGQTLAKDA
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHH
KHLTEVLSDFQTHIDGYAAPQISMDSPERLSA
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCC
>Mature Secondary Structure
MFWKAKHPVEPSKVDDVTETFIAIIDRTQATIQFELDGTIIDANANLLRATGYTLDELVG
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCEEEECCCCEEEECCCCHHHHHC
KHHSMFVDPGFAKTPAYAQFWERLGQGEILDDIYPRIAKDGSTVWMQAAYAPVFAADGTP
CCCCEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEHHHCCCEEECCCCC
TRVIKIATDITDRQSDIAEIAVGLEEMSNKTLSHRIAVSKHNDLAKLGTAFNLAQEQLSS
CEEEEEECCCCCHHHHHHHHHHHHHHHHCHHHHHHEEECCCCCHHHHHHHHHHHHHHHHH
ALDIAKDVSSGVEQTADDLSQASGALAQRTETQAATLEETAAALEEMSATVQATVGSTKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
VERAAKAATATAETGGKVVDNAVNAMSLIEKSSHDIARIISVMEEIAFQTNLLALNAGVE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCH
AARAGDAGRGFAVVASEVRALAQRASESAGEIKTLISGSSEHVASGVELVGRAGKELSNI
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ISSVSQISSNISDIANTTTEQATALTEINTGLSQLDQVTQQNTAMVAETSAAGQTLAKDA
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHH
KHLTEVLSDFQTHIDGYAAPQISMDSPERLSA
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]