| Definition | Jannaschia sp. CCS1 chromosome, complete genome. |
|---|---|
| Accession | NC_007802 |
| Length | 4,317,977 |
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The map label for this gene is holB [H]
Identifier: 89053767
GI number: 89053767
Start: 1236375
End: 1237499
Strand: Reverse
Name: holB [H]
Synonym: Jann_1276
Alternate gene names: 89053767
Gene position: 1237499-1236375 (Counterclockwise)
Preceding gene: 89053768
Following gene: 89053766
Centisome position: 28.66
GC content: 67.29
Gene sequence:
>1125_bases ATGTCCGATGACGCCCTACCCGAATCCGACCGCCTCGATGGGGCACCCCACCCGCGCGACGCCGCGCGCCTCTTCGGCCA TGCAAGCGCCGAGGCAGAGTTTCTGACAGCCGCCACCTCGGGCCGCCTGCCCCACGGCTGGCTTCTCACCGGACCCAAGG GCGTCGGCAAAGCCACCTTTGCCTGGCGCGCCGCGCGGTTTTTGCTGGCCACACCTCCGCCGGAAGACGACGGCATGTTC GGTGCACCGCCGCCGCCCACCTCGCTTGATATCGCGCCGGATCACCCCGTCGCCCGTCGCATGGCGGCGCTGAGCGAGCC CGGGCTGTTCCTGCTGCGCCGCCCCGTGGATGAGAAGGACCAAAAGAAGCTGAAGACCGTGATCACGGTCGACGAAGTGC GCGGATTGAAAGGGTTTTTCCATCTTTCGGCTGGGGGGCACCGCCGCGTCGTCATCGTCGACAGCGCCGATGAAATGAAC CCGTCGGCCGCCAATGCCCTGTTGAAGGAACTGGAGGAGCCGCCCGAAGGCGCGGTTCTGTTCCTGATCTCCCACCGCCC GTCGGGTCTTCTGCCGACCATCCGATCGCGCTGCCGGACGCTTCGGTTCAATCCTTTGGGGGATGCGGACCTTGCTGATG CGCTGGTCCAGGCGGGCGCTGACCCGCCCGAGGGCACGGCACTTGCCACTCTGGCACAAGGCTCCGCCGGGACAGCAATT TCGCTGGCGGATCAAGGCGGGCCGTCGCTCTATGCTGATATTGCCAAACTCTTGGGAACACTGCCGAATATGGACAGGCA ATTGGCTCTTCGCCTTGCGGATGGCGCCGCCGGAAAGGCCAATGAGGCGCGGTTCGACCTGACTCTGTCCTTGCTGGATA TGGCGCTCTCGCGGGCGGCACGCATGGGGGCGACCGGGCAGGCCCCGGACGAGATCACGCCGAATGAGGCCGCAACGCTC GCCCGTCTCGCCCCCTCCCCCCAGCATGCCCGCGAATGGGCCAGCCTCGCCCAATCGCTGACCGCCCGCGCGCGGCGTGG CAAGGCGGTCAACCTTGACCCTGCGGCGCTGGTGTTTGATATCTTCCTCGACCTGGACCGGATGGCGGCCCGGCTGGCCG CATGA
Upstream 100 bases:
>100_bases GGAGGCCTGACATCAGCCGCATGCCCCCGATGGGCCAAGCAAATTGATATACCATTGATCTACCCTGCCCGCCGCTTGCG CCCCGTGCTACATCTGCCCC
Downstream 100 bases:
>100_bases GGATCCGATGAGCACGCCTGCACTCGTAGACAGCCACTGCCACCTGGACTTCGACAGCCTCTCCGCAGAGCTGCCGGATG TCATCGCGCGCGCCTTGGAT
Product: DNA polymerase III subunit delta'
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 374; Mature: 373
Protein sequence:
>374_residues MSDDALPESDRLDGAPHPRDAARLFGHASAEAEFLTAATSGRLPHGWLLTGPKGVGKATFAWRAARFLLATPPPEDDGMF GAPPPPTSLDIAPDHPVARRMAALSEPGLFLLRRPVDEKDQKKLKTVITVDEVRGLKGFFHLSAGGHRRVVIVDSADEMN PSAANALLKELEEPPEGAVLFLISHRPSGLLPTIRSRCRTLRFNPLGDADLADALVQAGADPPEGTALATLAQGSAGTAI SLADQGGPSLYADIAKLLGTLPNMDRQLALRLADGAAGKANEARFDLTLSLLDMALSRAARMGATGQAPDEITPNEAATL ARLAPSPQHAREWASLAQSLTARARRGKAVNLDPAALVFDIFLDLDRMAARLAA
Sequences:
>Translated_374_residues MSDDALPESDRLDGAPHPRDAARLFGHASAEAEFLTAATSGRLPHGWLLTGPKGVGKATFAWRAARFLLATPPPEDDGMF GAPPPPTSLDIAPDHPVARRMAALSEPGLFLLRRPVDEKDQKKLKTVITVDEVRGLKGFFHLSAGGHRRVVIVDSADEMN PSAANALLKELEEPPEGAVLFLISHRPSGLLPTIRSRCRTLRFNPLGDADLADALVQAGADPPEGTALATLAQGSAGTAI SLADQGGPSLYADIAKLLGTLPNMDRQLALRLADGAAGKANEARFDLTLSLLDMALSRAARMGATGQAPDEITPNEAATL ARLAPSPQHAREWASLAQSLTARARRGKAVNLDPAALVFDIFLDLDRMAARLAA >Mature_373_residues SDDALPESDRLDGAPHPRDAARLFGHASAEAEFLTAATSGRLPHGWLLTGPKGVGKATFAWRAARFLLATPPPEDDGMFG APPPPTSLDIAPDHPVARRMAALSEPGLFLLRRPVDEKDQKKLKTVITVDEVRGLKGFFHLSAGGHRRVVIVDSADEMNP SAANALLKELEEPPEGAVLFLISHRPSGLLPTIRSRCRTLRFNPLGDADLADALVQAGADPPEGTALATLAQGSAGTAIS LADQGGPSLYADIAKLLGTLPNMDRQLALRLADGAAGKANEARFDLTLSLLDMALSRAARMGATGQAPDEITPNEAATLA RLAPSPQHAREWASLAQSLTARARRGKAVNLDPAALVFDIFLDLDRMAARLAA
Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]
COG id: COG0470
COG function: function code L; ATPase involved in DNA replication
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: NA
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003959 - InterPro: IPR004622 [H]
Pfam domain/function: PF00004 AAA [H]
EC number: =2.7.7.7 [H]
Molecular weight: Translated: 39494; Mature: 39363
Theoretical pI: Translated: 6.32; Mature: 6.32
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSDDALPESDRLDGAPHPRDAARLFGHASAEAEFLTAATSGRLPHGWLLTGPKGVGKATF CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHEEEEHHCCCCCCCEEEECCCCCCCHHH AWRAARFLLATPPPEDDGMFGAPPPPTSLDIAPDHPVARRMAALSEPGLFLLRRPVDEKD HHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCHHH QKKLKTVITVDEVRGLKGFFHLSAGGHRRVVIVDSADEMNPSAANALLKELEEPPEGAVL HHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEE FLISHRPSGLLPTIRSRCRTLRFNPLGDADLADALVQAGADPPEGTALATLAQGSAGTAI EEEECCCCCCCHHHHHHHHEECCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEE SLADQGGPSLYADIAKLLGTLPNMDRQLALRLADGAAGKANEARFDLTLSLLDMALSRAA EECCCCCCHHHHHHHHHHHHCCCCCHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH RMGATGQAPDEITPNEAATLARLAPSPQHAREWASLAQSLTARARRGKAVNLDPAALVFD HCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH IFLDLDRMAARLAA HHHHHHHHHHHHCC >Mature Secondary Structure SDDALPESDRLDGAPHPRDAARLFGHASAEAEFLTAATSGRLPHGWLLTGPKGVGKATF CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHEEEEHHCCCCCCCEEEECCCCCCCHHH AWRAARFLLATPPPEDDGMFGAPPPPTSLDIAPDHPVARRMAALSEPGLFLLRRPVDEKD HHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCHHH QKKLKTVITVDEVRGLKGFFHLSAGGHRRVVIVDSADEMNPSAANALLKELEEPPEGAVL HHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEE FLISHRPSGLLPTIRSRCRTLRFNPLGDADLADALVQAGADPPEGTALATLAQGSAGTAI EEEECCCCCCCHHHHHHHHEECCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEE SLADQGGPSLYADIAKLLGTLPNMDRQLALRLADGAAGKANEARFDLTLSLLDMALSRAA EECCCCCCHHHHHHHHHHHHCCCCCHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH RMGATGQAPDEITPNEAATLARLAPSPQHAREWASLAQSLTARARRGKAVNLDPAALVFD HCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH IFLDLDRMAARLAA HHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8550441; 10984043 [H]