Click here to switch to the map view.

The map label for this gene is pucD [H]

Identifier: 89053427

GI number: 89053427

Start: 890864

End: 893302

Strand: Reverse

Name: pucD [H]

Synonym: Jann_0936

Alternate gene names: 89053427

Gene position: 893302-890864 (Counterclockwise)

Preceding gene: 89053428

Following gene: 89053426

Centisome position: 20.69

GC content: 64.33

Gene sequence:

>2439_bases
ATGAGCGTGCACAAACCCCTGCCCCATGATGCCGCCCGTCTGCATGTCACCGGGGCGGCCCGCTATGTGGATGACATTCC
GACGCCGCCCGATTGCCTGCACCTGGCCTTCGGCCTGTCGCGCGTCGCGAAGGGCCACATCACGGATATGGACCTGGATC
GCACACGCTCATCCGCAGGCGTCTTCGCCGTGCTCACAGGCGCGGACCTTTCGCCAATCCCCGATTGTTCCCCCTCCAAT
CACGACGAGCCACTTTTGAGCGATGGCGCGATCCATTACGCGGGCCAGCCGCTGTTTCTGGTCGCGGCAGACAGCCACCT
CGCGGCGCGGCGCGCTGTGGCTCTGGCTGATGTGCAGATCCGTGGGGAAGAGCCGTGTCTGACGATTCAACAAGCGCAGG
CCGCCGACAGCCGGTTCGAGGATGGACCGCGTATCTACGCCAAGGGCGACGTGGATCAGGCGCTGACCTCTGCCGCGCAT
ATCGTTGAGGGTCGTGTCGACATCGGCGGGCAGGAGCACTTCTATCTTGAGGGGCAATCCGCCCTCGCCCTGCCGCAGGA
GGGTGGCGACATGGTGGTCCATTCCTCCTCCCAACACCCGACCGAGATCCAGCACAAGGTGGCCGACGCCCTTGACCTGC
CCATGCATGCCGTCAGGGTCGAAGTGCGGCGCATGGGCGGCGGCTTTGGCGGGAAGGAAAGCCAGGGCAATCACCTGGCC
ATTGCCTGCGCGATCGTTGCGGCCCGCACCGGGCGCCCTTGCAAGATGCGCTATGACCGCGACGACGATTTCATTATCAC
CGGCAAGCGCCACGATGCCCGGGTGATGTACCGCGCCGGGTTTAACGCCGACGGTCGCATCCTTGGCGTCGATTTCACCC
AGCATATCCGCTGCGGATGGGCGATGGACCTGTCCCTGCCCGTGGCCGACCGCGCCATGTTGCATGCAGACAACGCCTAT
CTTCTGCCTGCCGCGCGGATCACCTCCCATCGGTGGAAGACCAACACCCAATCCGCCACGGCCTTTCGTGGGTTCGGCGG
CCCTCAAGGCATGGTCGGGATCGAGCGGGTGATGGACCACGCGGCGCATGCCTTGGGCATGGATCCCTTAGAGGTGCGGC
GTGTAAATTACTACCGGGCGGCACCTGAGATGGACAGCGGACCCACCGGGGAGCGTTTGTCTGGCAAGATGAAAGGAGGG
CGCCTGGAGACCGCTGAACTTGCCGGGCGTGGCGCCGTACGCGTCAAAGGCGGCGGGGGCGCGCAAAGGTTCGGCGGTGC
GCATTCGCCGGTGGCGGGCGGGCTTGCTGCCAACACGACACCCTATGGGATGGAGGTGGAGGATTTCATCCTTCACGACA
TGACGAAGTCTCTGGCGCAGGACTGCGATTATGCGGATCGCGTGCGGGCGGTCGAGGAGTGGAATACAAGGGAGCCGATC
CTGAAGCGCGGCATCGCTCTGACGCCGGTGAAGTTCGGGATCTCCTTCACGCTCACCCATCTCAACCAGGCCGGCGCTTT
GGTCCATGTCTACCAGGACGGCTCCATCCACATGAACCATGGCGGGACCGAGATGGGCCAGGGTCTGTTCCAGAAGGTGG
CCCAAGTGGCCGCGAGCCGGTTCGGCGTATCTTTGGACCGCGTGAAAATTACCGCCACGGACACTGGAAAGGTGCCCAAC
ACATCCGCGACTGCCGCGTCCTCGGGCACAGATCTCAACGGGATGGCCGTGAAAGCCGCCTGCGATAAGATCCGGGACCG
GATCGCAGAGGAGGTGGCGGGTGCCTTGCAGGCGGAGCCTGCGGATGTGCGGTTCGAGGACGGCATGGTGCGCGCAGACA
ACGCTGAGATGCCGTTTGAGGAGGCCGTCCAATGCACCTACATGGCGCGGATCAGCCTCAGCGCCACGGGCTTCTACAAG
ACCCCCAAGATCGAATGGGACCGGATCAAGGGCCAAGGCCGCCCCTTCCTCTACTTCGCCTATGGCGCCGCTTGCTCCGA
GGTTGTCATCGACACTCTCACCGGCGAAAACCGCATCCTGCGCACCGACATCCTCCACGACGCGGGCGCGTCCCTGAACC
CTGCGCTCGACATCGGGCAGGTGGAGGGTGGCTTCATTCAGGGGGCCGGATGGCTCACGATGGAAGAGTTGGTTTGGGAC
GACAAAGGCGCGCTGAAAACCCATGCGCCATCGACCTACAAGATCCCCTGCGCGTCTGATGCGCCCGACATCTTCAACGT
TTCGCTCTACGATGCACAGAACCGCGAAGACACCATCTACCGCTCCAAGGCGGTGGGTGAGCCGCCCTTCATGCTTGGCA
TCAGCGTGTTCTCCGCCCTCGGGCATGCCTGTGCCGCTGCCGGTTCCACCTTCCCTGACCTGCAAGCCCCGGCCACCGCA
GAAGCGGTCTTGGCCGCCGTGGGTCGCGCCCGATCATGA

Upstream 100 bases:

>100_bases
GCGCGTCTGCCGGCTATCGGCTTGAGGCGGCGCAAAACATGCTCTTGCGCTACATGGCCGAGATGTCTGGCCAGGCAACC
AGCGTGCTGGAGGTGCGGCC

Downstream 100 bases:

>100_bases
CCGCGATCCGCGTGACCATCACGCAGGTCAAAGGCTCCGCACCGCGCGACACGGGCACGTCGATGCTGGTCTTTGCGGAC
CGGATCGAAGGCACAATTGG

Product: xanthine oxidase

Products: NA

Alternate protein names: XDHase subunit D [H]

Number of amino acids: Translated: 812; Mature: 811

Protein sequence:

>812_residues
MSVHKPLPHDAARLHVTGAARYVDDIPTPPDCLHLAFGLSRVAKGHITDMDLDRTRSSAGVFAVLTGADLSPIPDCSPSN
HDEPLLSDGAIHYAGQPLFLVAADSHLAARRAVALADVQIRGEEPCLTIQQAQAADSRFEDGPRIYAKGDVDQALTSAAH
IVEGRVDIGGQEHFYLEGQSALALPQEGGDMVVHSSSQHPTEIQHKVADALDLPMHAVRVEVRRMGGGFGGKESQGNHLA
IACAIVAARTGRPCKMRYDRDDDFIITGKRHDARVMYRAGFNADGRILGVDFTQHIRCGWAMDLSLPVADRAMLHADNAY
LLPAARITSHRWKTNTQSATAFRGFGGPQGMVGIERVMDHAAHALGMDPLEVRRVNYYRAAPEMDSGPTGERLSGKMKGG
RLETAELAGRGAVRVKGGGGAQRFGGAHSPVAGGLAANTTPYGMEVEDFILHDMTKSLAQDCDYADRVRAVEEWNTREPI
LKRGIALTPVKFGISFTLTHLNQAGALVHVYQDGSIHMNHGGTEMGQGLFQKVAQVAASRFGVSLDRVKITATDTGKVPN
TSATAASSGTDLNGMAVKAACDKIRDRIAEEVAGALQAEPADVRFEDGMVRADNAEMPFEEAVQCTYMARISLSATGFYK
TPKIEWDRIKGQGRPFLYFAYGAACSEVVIDTLTGENRILRTDILHDAGASLNPALDIGQVEGGFIQGAGWLTMEELVWD
DKGALKTHAPSTYKIPCASDAPDIFNVSLYDAQNREDTIYRSKAVGEPPFMLGISVFSALGHACAAAGSTFPDLQAPATA
EAVLAAVGRARS

Sequences:

>Translated_812_residues
MSVHKPLPHDAARLHVTGAARYVDDIPTPPDCLHLAFGLSRVAKGHITDMDLDRTRSSAGVFAVLTGADLSPIPDCSPSN
HDEPLLSDGAIHYAGQPLFLVAADSHLAARRAVALADVQIRGEEPCLTIQQAQAADSRFEDGPRIYAKGDVDQALTSAAH
IVEGRVDIGGQEHFYLEGQSALALPQEGGDMVVHSSSQHPTEIQHKVADALDLPMHAVRVEVRRMGGGFGGKESQGNHLA
IACAIVAARTGRPCKMRYDRDDDFIITGKRHDARVMYRAGFNADGRILGVDFTQHIRCGWAMDLSLPVADRAMLHADNAY
LLPAARITSHRWKTNTQSATAFRGFGGPQGMVGIERVMDHAAHALGMDPLEVRRVNYYRAAPEMDSGPTGERLSGKMKGG
RLETAELAGRGAVRVKGGGGAQRFGGAHSPVAGGLAANTTPYGMEVEDFILHDMTKSLAQDCDYADRVRAVEEWNTREPI
LKRGIALTPVKFGISFTLTHLNQAGALVHVYQDGSIHMNHGGTEMGQGLFQKVAQVAASRFGVSLDRVKITATDTGKVPN
TSATAASSGTDLNGMAVKAACDKIRDRIAEEVAGALQAEPADVRFEDGMVRADNAEMPFEEAVQCTYMARISLSATGFYK
TPKIEWDRIKGQGRPFLYFAYGAACSEVVIDTLTGENRILRTDILHDAGASLNPALDIGQVEGGFIQGAGWLTMEELVWD
DKGALKTHAPSTYKIPCASDAPDIFNVSLYDAQNREDTIYRSKAVGEPPFMLGISVFSALGHACAAAGSTFPDLQAPATA
EAVLAAVGRARS
>Mature_811_residues
SVHKPLPHDAARLHVTGAARYVDDIPTPPDCLHLAFGLSRVAKGHITDMDLDRTRSSAGVFAVLTGADLSPIPDCSPSNH
DEPLLSDGAIHYAGQPLFLVAADSHLAARRAVALADVQIRGEEPCLTIQQAQAADSRFEDGPRIYAKGDVDQALTSAAHI
VEGRVDIGGQEHFYLEGQSALALPQEGGDMVVHSSSQHPTEIQHKVADALDLPMHAVRVEVRRMGGGFGGKESQGNHLAI
ACAIVAARTGRPCKMRYDRDDDFIITGKRHDARVMYRAGFNADGRILGVDFTQHIRCGWAMDLSLPVADRAMLHADNAYL
LPAARITSHRWKTNTQSATAFRGFGGPQGMVGIERVMDHAAHALGMDPLEVRRVNYYRAAPEMDSGPTGERLSGKMKGGR
LETAELAGRGAVRVKGGGGAQRFGGAHSPVAGGLAANTTPYGMEVEDFILHDMTKSLAQDCDYADRVRAVEEWNTREPIL
KRGIALTPVKFGISFTLTHLNQAGALVHVYQDGSIHMNHGGTEMGQGLFQKVAQVAASRFGVSLDRVKITATDTGKVPNT
SATAASSGTDLNGMAVKAACDKIRDRIAEEVAGALQAEPADVRFEDGMVRADNAEMPFEEAVQCTYMARISLSATGFYKT
PKIEWDRIKGQGRPFLYFAYGAACSEVVIDTLTGENRILRTDILHDAGASLNPALDIGQVEGGFIQGAGWLTMEELVWDD
KGALKTHAPSTYKIPCASDAPDIFNVSLYDAQNREDTIYRSKAVGEPPFMLGISVFSALGHACAAAGSTFPDLQAPATAE
AVLAAVGRARS

Specific function: Oxidizes hypoxanthine and xanthine to uric acid [H]

COG id: COG4631

COG function: function code F; Xanthine dehydrogenase, molybdopterin-binding subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=811, Percent_Identity=36.3748458692972, Blast_Score=443, Evalue=1e-124,
Organism=Homo sapiens, GI71773480, Length=808, Percent_Identity=35.0247524752475, Blast_Score=437, Evalue=1e-122,
Organism=Escherichia coli, GI1789246, Length=797, Percent_Identity=24.7176913425345, Blast_Score=172, Evalue=9e-44,
Organism=Escherichia coli, GI1789230, Length=457, Percent_Identity=28.6652078774617, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1786478, Length=285, Percent_Identity=28.7719298245614, Blast_Score=87, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI32566215, Length=816, Percent_Identity=31.25, Blast_Score=341, Evalue=8e-94,
Organism=Caenorhabditis elegans, GI17540638, Length=395, Percent_Identity=41.7721518987342, Blast_Score=280, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17539860, Length=328, Percent_Identity=33.8414634146341, Blast_Score=179, Evalue=8e-45,
Organism=Drosophila melanogaster, GI17737937, Length=379, Percent_Identity=41.1609498680739, Blast_Score=289, Evalue=7e-78,
Organism=Drosophila melanogaster, GI24647199, Length=814, Percent_Identity=27.027027027027, Blast_Score=228, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24647195, Length=353, Percent_Identity=31.728045325779, Blast_Score=164, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24647197, Length=353, Percent_Identity=31.728045325779, Blast_Score=164, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24647193, Length=364, Percent_Identity=32.4175824175824, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24647201, Length=359, Percent_Identity=33.1476323119777, Blast_Score=155, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR017609 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 86976; Mature: 86845

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVHKPLPHDAARLHVTGAARYVDDIPTPPDCLHLAFGLSRVAKGHITDMDLDRTRSSAG
CCCCCCCCCCCEEEEEEEHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCC
VFAVLTGADLSPIPDCSPSNHDEPLLSDGAIHYAGQPLFLVAADSHLAARRAVALADVQI
EEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEEECCCHHHHHEEEEEEEEE
RGEEPCLTIQQAQAADSRFEDGPRIYAKGDVDQALTSAAHIVEGRVDIGGQEHFYLEGQS
ECCCCCEEEHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCEECCCCEEEEEECCC
ALALPQEGGDMVVHSSSQHPTEIQHKVADALDLPMHAVRVEVRRMGGGFGGKESQGNHLA
EEECCCCCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEE
IACAIVAARTGRPCKMRYDRDDDFIITGKRHDARVMYRAGFNADGRILGVDFTQHIRCGW
EEEEEEHHCCCCCEEEEECCCCCEEEECCCCCCEEEEEECCCCCCEEEEECHHHHEEECE
AMDLSLPVADRAMLHADNAYLLPAARITSHRWKTNTQSATAFRGFGGPQGMVGIERVMDH
EEEECCCCCCCCEEECCCEEEEEHHHHHCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHH
AAHALGMDPLEVRRVNYYRAAPEMDSGPTGERLSGKMKGGRLETAELAGRGAVRVKGGGG
HHHHCCCCHHHHHEEEEEECCCCCCCCCCCHHHCCCCCCCEEEHHHHCCCCEEEEECCCC
AQRFGGAHSPVAGGLAANTTPYGMEVEDFILHDMTKSLAQDCDYADRVRAVEEWNTREPI
HHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHH
LKRGIALTPVKFGISFTLTHLNQAGALVHVYQDGSIHMNHGGTEMGQGLFQKVAQVAASR
HHCCCEEEEEEECEEEEEEECCCCCCEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHH
FGVSLDRVKITATDTGKVPNTSATAASSGTDLNGMAVKAACDKIRDRIAEEVAGALQAEP
HCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCC
ADVRFEDGMVRADNAEMPFEEAVQCTYMARISLSATGFYKTPKIEWDRIKGQGRPFLYFA
CCEEECCCEEEECCCCCCHHHHHHEEEEEEEEEEECCCCCCCCCCHHHHCCCCCEEEEEE
YGAACSEVVIDTLTGENRILRTDILHDAGASLNPALDIGQVEGGFIQGAGWLTMEELVWD
CCCHHHHHHHHHCCCCCEEEEEHHHHHCCCCCCCCCCCCCCCCCEEECCCCEEHHHHHCC
DKGALKTHAPSTYKIPCASDAPDIFNVSLYDAQNREDTIYRSKAVGEPPFMLGISVFSAL
CCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHH
GHACAAAGSTFPDLQAPATAEAVLAAVGRARS
HHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVHKPLPHDAARLHVTGAARYVDDIPTPPDCLHLAFGLSRVAKGHITDMDLDRTRSSAG
CCCCCCCCCCEEEEEEEHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCC
VFAVLTGADLSPIPDCSPSNHDEPLLSDGAIHYAGQPLFLVAADSHLAARRAVALADVQI
EEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEEECCCHHHHHEEEEEEEEE
RGEEPCLTIQQAQAADSRFEDGPRIYAKGDVDQALTSAAHIVEGRVDIGGQEHFYLEGQS
ECCCCCEEEHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCEECCCCEEEEEECCC
ALALPQEGGDMVVHSSSQHPTEIQHKVADALDLPMHAVRVEVRRMGGGFGGKESQGNHLA
EEECCCCCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEE
IACAIVAARTGRPCKMRYDRDDDFIITGKRHDARVMYRAGFNADGRILGVDFTQHIRCGW
EEEEEEHHCCCCCEEEEECCCCCEEEECCCCCCEEEEEECCCCCCEEEEECHHHHEEECE
AMDLSLPVADRAMLHADNAYLLPAARITSHRWKTNTQSATAFRGFGGPQGMVGIERVMDH
EEEECCCCCCCCEEECCCEEEEEHHHHHCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHH
AAHALGMDPLEVRRVNYYRAAPEMDSGPTGERLSGKMKGGRLETAELAGRGAVRVKGGGG
HHHHCCCCHHHHHEEEEEECCCCCCCCCCCHHHCCCCCCCEEEHHHHCCCCEEEEECCCC
AQRFGGAHSPVAGGLAANTTPYGMEVEDFILHDMTKSLAQDCDYADRVRAVEEWNTREPI
HHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHH
LKRGIALTPVKFGISFTLTHLNQAGALVHVYQDGSIHMNHGGTEMGQGLFQKVAQVAASR
HHCCCEEEEEEECEEEEEEECCCCCCEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHH
FGVSLDRVKITATDTGKVPNTSATAASSGTDLNGMAVKAACDKIRDRIAEEVAGALQAEP
HCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCC
ADVRFEDGMVRADNAEMPFEEAVQCTYMARISLSATGFYKTPKIEWDRIKGQGRPFLYFA
CCEEECCCEEEECCCCCCHHHHHHEEEEEEEEEEECCCCCCCCCCHHHHCCCCCEEEEEE
YGAACSEVVIDTLTGENRILRTDILHDAGASLNPALDIGQVEGGFIQGAGWLTMEELVWD
CCCHHHHHHHHHCCCCCEEEEEHHHHHCCCCCCCCCCCCCCCCCEEECCCCEEHHHHHCC
DKGALKTHAPSTYKIPCASDAPDIFNVSLYDAQNREDTIYRSKAVGEPPFMLGISVFSAL
CCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHH
GHACAAAGSTFPDLQAPATAEAVLAAVGRARS
HHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]