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The map label for this gene is etfA [H]

Identifier: 89053036

GI number: 89053036

Start: 534292

End: 535218

Strand: Reverse

Name: etfA [H]

Synonym: Jann_0545

Alternate gene names: 89053036

Gene position: 535218-534292 (Counterclockwise)

Preceding gene: 89053037

Following gene: 89053034

Centisome position: 12.4

GC content: 64.19

Gene sequence:

>927_bases
ATGGCTGTTCTTCTCCTTGCCGAAGTGAATGCCGGTGAACTGGCGATGGATGCGACCGCGAAGGCGGTGACCGCCGCCGC
GCAGCTGGGGGATGTCACGGTGCTCTGCGCCGGTGCGTCCGCCAAAGCTGCCGCCGATGAGGCCGCAACGATTGCAGGTG
TTGCACGCGTGCTTTGCGCCGAAGACGAGGCTCTGGGCCACCGTCTGGCGGAGGCCACCGCCGCGTTGATCGTAAGCCTT
GCCGGAGACTATTCGCACATCGTGGCCCCGGCCACGACGGATGCGAAAAATGTCATGCCCCGCGTGGCGGCTCTGCTGGA
TGTGATGGTCATCTCCGACGCCTCTGGCGTGGTGGACGCCGACACGTTCGAGCGTCCGATCTATGCGGGCAATGCGATCC
AAACTGTCAAATCTGCGGATGCCACCAAGGTCGTCACCTTCCGCACCTCCACCTTCGATGCGGCTCCCACGGGCGGTTCG
GCGAGCGTGGAGATGATCGACGCCGCGGGCAACCCGGGCCTGTCATCCTGGATCGAAGACAAGTTTGCAGCCAGCGACCG
GCCGGAACTGACCTCGGCGGGCATCGTTGTGTCTGGTGGCCGTGGCGTCGGCTCGGAAGAGCAATTCGCGCTGATCGAGG
GGCTGGCGGACAAGCTGGGTGCCGCCGTCGGTGCATCCCGCGCTGCTGTCGACTCCGGCTACGCGCCCAACGACTGGCAG
GTCGGTCAGACTGGCAAAGTCGTGGCCCCGGACCTTTACGTCGCTGTCGGAATTTCGGGAGCGATCCAGCACCTCGCCGG
CATGAAGGATTCCAAGGTCATTGTCGCAATCAACAAAGACGAGGAGGCACCGATTTTCCAGGTCGCGGATTACGGCCTGG
TGGCCGACCTCTTCGACGCCGTCCCGGAATTGACCAGCAAGCTCTGA

Upstream 100 bases:

>100_bases
GTGACAACGTCCGAGCCCGAAGCCCGTGCCGCTGGCGTCAAGGTGGCCTCGGTCGATGAACTTCTGACGAAACTCAAAGA
TGAAGCGGGGGTCCTTTGAA

Downstream 100 bases:

>100_bases
ACCTTGCGACAGCCAATCAATCCAGCCCCACCGGAGCAATCCGGCGGGGCTTTTTTCATGGGATCAGGAGCTTGAGCCAG
TTGGGTGAGGAGTACGGCTT

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MAVLLLAEVNAGELAMDATAKAVTAAAQLGDVTVLCAGASAKAAADEAATIAGVARVLCAEDEALGHRLAEATAALIVSL
AGDYSHIVAPATTDAKNVMPRVAALLDVMVISDASGVVDADTFERPIYAGNAIQTVKSADATKVVTFRTSTFDAAPTGGS
ASVEMIDAAGNPGLSSWIEDKFAASDRPELTSAGIVVSGGRGVGSEEQFALIEGLADKLGAAVGASRAAVDSGYAPNDWQ
VGQTGKVVAPDLYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFDAVPELTSKL

Sequences:

>Translated_308_residues
MAVLLLAEVNAGELAMDATAKAVTAAAQLGDVTVLCAGASAKAAADEAATIAGVARVLCAEDEALGHRLAEATAALIVSL
AGDYSHIVAPATTDAKNVMPRVAALLDVMVISDASGVVDADTFERPIYAGNAIQTVKSADATKVVTFRTSTFDAAPTGGS
ASVEMIDAAGNPGLSSWIEDKFAASDRPELTSAGIVVSGGRGVGSEEQFALIEGLADKLGAAVGASRAAVDSGYAPNDWQ
VGQTGKVVAPDLYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFDAVPELTSKL
>Mature_307_residues
AVLLLAEVNAGELAMDATAKAVTAAAQLGDVTVLCAGASAKAAADEAATIAGVARVLCAEDEALGHRLAEATAALIVSLA
GDYSHIVAPATTDAKNVMPRVAALLDVMVISDASGVVDADTFERPIYAGNAIQTVKSADATKVVTFRTSTFDAAPTGGSA
SVEMIDAAGNPGLSSWIEDKFAASDRPELTSAGIVVSGGRGVGSEEQFALIEGLADKLGAAVGASRAAVDSGYAPNDWQV
GQTGKVVAPDLYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFDAVPELTSKL

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=311, Percent_Identity=54.0192926045016, Blast_Score=304, Evalue=8e-83,
Organism=Homo sapiens, GI189181759, Length=274, Percent_Identity=56.9343065693431, Blast_Score=293, Evalue=2e-79,
Organism=Escherichia coli, GI1786226, Length=232, Percent_Identity=37.0689655172414, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787990, Length=227, Percent_Identity=33.4801762114537, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082157, Length=129, Percent_Identity=37.984496124031, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17506929, Length=311, Percent_Identity=54.3408360128617, Blast_Score=305, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6325261, Length=286, Percent_Identity=46.1538461538462, Blast_Score=244, Evalue=2e-65,
Organism=Drosophila melanogaster, GI17136898, Length=312, Percent_Identity=54.8076923076923, Blast_Score=302, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24652801, Length=312, Percent_Identity=54.8076923076923, Blast_Score=302, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31072; Mature: 30941

Theoretical pI: Translated: 4.12; Mature: 4.12

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLLLAEVNAGELAMDATAKAVTAAAQLGDVTVLCAGASAKAAADEAATIAGVARVLCA
CEEEEEEECCCCCEEHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHC
EDEALGHRLAEATAALIVSLAGDYSHIVAPATTDAKNVMPRVAALLDVMVISDASGVVDA
CCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEC
DTFERPIYAGNAIQTVKSADATKVVTFRTSTFDAAPTGGSASVEMIDAAGNPGLSSWIED
HHCCCCEECCCHHHHHHCCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHH
KFAASDRPELTSAGIVVSGGRGVGSEEQFALIEGLADKLGAAVGASRAAVDSGYAPNDWQ
HHCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
VGQTGKVVAPDLYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFDA
CCCCCCEECCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCHHHHHHHHH
VPELTSKL
HHHHHHCC
>Mature Secondary Structure 
AVLLLAEVNAGELAMDATAKAVTAAAQLGDVTVLCAGASAKAAADEAATIAGVARVLCA
EEEEEEECCCCCEEHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHC
EDEALGHRLAEATAALIVSLAGDYSHIVAPATTDAKNVMPRVAALLDVMVISDASGVVDA
CCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEC
DTFERPIYAGNAIQTVKSADATKVVTFRTSTFDAAPTGGSASVEMIDAAGNPGLSSWIED
HHCCCCEECCCHHHHHHCCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHH
KFAASDRPELTSAGIVVSGGRGVGSEEQFALIEGLADKLGAAVGASRAAVDSGYAPNDWQ
HHCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
VGQTGKVVAPDLYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFDA
CCCCCCEECCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCHHHHHHHHH
VPELTSKL
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8376381; 1576992; 10026281 [H]