Click here to switch to the map view.

The map label for this gene is aroC

Identifier: 89052822

GI number: 89052822

Start: 336913

End: 338025

Strand: Direct

Name: aroC

Synonym: Jann_0331

Alternate gene names: 89052822

Gene position: 336913-338025 (Clockwise)

Preceding gene: 89052818

Following gene: 89052823

Centisome position: 7.8

GC content: 62.35

Gene sequence:

>1113_bases
ATGAGTATGAATTCCTACGGTCACCTGTTCCGCGTCACCACCTGGGGCGAAAGCCATGGACCTGCCCTGGGCGCGACAGT
TGATGGCTGCCCTCCGGGGATCGACGTCGATGCGGCCGCGATCCAGCACTGGCTCGACCGTCGCAAACCTGGCCAGAACA
AATACACCACCCAGCGGCGAGAGGCTGATGAGGTGGAGATTTTGTCGGGCGTCTATGAAGGACAGTCCACCGGCACCCCC
ATCCAGCTCATGATCCGCAACACCGATCAGCGATCCAAGGATTACGGCGATATTGCCGAGAAGTTCCGGCCCGGCCATGC
GGACATTACCTATTGGCAGAAATACGGTATCCGTGATCCGCGTGGCGGCGGACGGTCAAGCGCGCGTGAGACGGCAGCAC
GGGTCGCCGCGGGTGGCGTGGCGCGTCTGGCGCTTGCGGCGCTGGTGCCTGCGGTGAAGATCACAGGTTACATGGTGCAA
ATGGGGCCGCACGGGATTGATCGCGAGTGCTTCGATCTGGCGCAGGTGGACGAAAACCCATTCTGGGTCCCCGATGCCAA
GGCCGCTGATGAGTGGGCCGCCTACTTGGATGGTTTGCGCAAGTCCGGCGACAGCGTCGGTGCCGTGATTGAGGTTCGCG
CCAGCGGGCTGCCCGCAGGTCTTGGGGCGCCGATCTATGGCAAGCTGGATACCGATCTGGCCGCCGCGATGATGAGCATC
AATGCCGTCAAAGGCGTGGAGATCGGCGACGGCATGGCGGCCGCGGCGCTGACCGGCTCGGCCAATGCGGATGAGATCCA
TATGGGCGATAATGGCCCTGAATATTCCTCAAACCACGCGGGCGGCATCCTTGGCGGTATCTCCACCGGGCAGGACGTCA
TCGTCCGGTTTGCGGTCAAACCGACATCCTCCATCCTCACGCCGCGCGCGACGATCACCAAGGCGGGCACCCCGGCCGAG
ATCATCACCAAAGGCCGCCACGATCCCTGTGTGGGAATCAGGGCTGTGCCGGTTGGCGAGGCGATGATGGCCTGTGTCGT
GCTAGACCACATTTTGCTGCAAAGAGGGCAAATTGGTGGCAAAGTCGGGGAAACCCGGGGAAAAATCGGATAA

Upstream 100 bases:

>100_bases
AGATGCGCGAGCCCCCCCGAGGTACCGCTAGACGTAGGGCACGGATGGGCGGACCGCAAGCGGCTTGGCAAAAGGGTCGC
ACAGGGATAACTCAGGCGGC

Downstream 100 bases:

>100_bases
GGTTTTATTAAACCTTTAAGGGTTTTTCGGCTAATCCGCTGGTTCTCGGTACTTTGATGACATGGATTGAACAATGGGGC
AAAACTGTCCAATCTTTGCC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSMNSYGHLFRVTTWGESHGPALGATVDGCPPGIDVDAAAIQHWLDRRKPGQNKYTTQRREADEVEILSGVYEGQSTGTP
IQLMIRNTDQRSKDYGDIAEKFRPGHADITYWQKYGIRDPRGGGRSSARETAARVAAGGVARLALAALVPAVKITGYMVQ
MGPHGIDRECFDLAQVDENPFWVPDAKAADEWAAYLDGLRKSGDSVGAVIEVRASGLPAGLGAPIYGKLDTDLAAAMMSI
NAVKGVEIGDGMAAAALTGSANADEIHMGDNGPEYSSNHAGGILGGISTGQDVIVRFAVKPTSSILTPRATITKAGTPAE
IITKGRHDPCVGIRAVPVGEAMMACVVLDHILLQRGQIGGKVGETRGKIG

Sequences:

>Translated_370_residues
MSMNSYGHLFRVTTWGESHGPALGATVDGCPPGIDVDAAAIQHWLDRRKPGQNKYTTQRREADEVEILSGVYEGQSTGTP
IQLMIRNTDQRSKDYGDIAEKFRPGHADITYWQKYGIRDPRGGGRSSARETAARVAAGGVARLALAALVPAVKITGYMVQ
MGPHGIDRECFDLAQVDENPFWVPDAKAADEWAAYLDGLRKSGDSVGAVIEVRASGLPAGLGAPIYGKLDTDLAAAMMSI
NAVKGVEIGDGMAAAALTGSANADEIHMGDNGPEYSSNHAGGILGGISTGQDVIVRFAVKPTSSILTPRATITKAGTPAE
IITKGRHDPCVGIRAVPVGEAMMACVVLDHILLQRGQIGGKVGETRGKIG
>Mature_369_residues
SMNSYGHLFRVTTWGESHGPALGATVDGCPPGIDVDAAAIQHWLDRRKPGQNKYTTQRREADEVEILSGVYEGQSTGTPI
QLMIRNTDQRSKDYGDIAEKFRPGHADITYWQKYGIRDPRGGGRSSARETAARVAAGGVARLALAALVPAVKITGYMVQM
GPHGIDRECFDLAQVDENPFWVPDAKAADEWAAYLDGLRKSGDSVGAVIEVRASGLPAGLGAPIYGKLDTDLAAAMMSIN
AVKGVEIGDGMAAAALTGSANADEIHMGDNGPEYSSNHAGGILGGISTGQDVIVRFAVKPTSSILTPRATITKAGTPAEI
ITKGRHDPCVGIRAVPVGEAMMACVVLDHILLQRGQIGGKVGETRGKIG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=357, Percent_Identity=59.3837535014006, Blast_Score=393, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6321290, Length=369, Percent_Identity=41.7344173441734, Blast_Score=278, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_JANSC (Q28VL4)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_508273.1
- HSSP:   P63611
- ProteinModelPortal:   Q28VL4
- SMR:   Q28VL4
- STRING:   Q28VL4
- GeneID:   3932772
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_0331
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- PhylomeDB:   Q28VL4
- ProtClustDB:   PRK05382
- BioCyc:   JSP290400:JANN_0331-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 38942; Mature: 38810

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMNSYGHLFRVTTWGESHGPALGATVDGCPPGIDVDAAAIQHWLDRRKPGQNKYTTQRR
CCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHH
EADEVEILSGVYEGQSTGTPIQLMIRNTDQRSKDYGDIAEKFRPGHADITYWQKYGIRDP
CCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCC
RGGGRSSARETAARVAAGGVARLALAALVPAVKITGYMVQMGPHGIDRECFDLAQVDENP
CCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHCCCCC
FWVPDAKAADEWAAYLDGLRKSGDSVGAVIEVRASGLPAGLGAPIYGKLDTDLAAAMMSI
CCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHH
NAVKGVEIGDGMAAAALTGSANADEIHMGDNGPEYSSNHAGGILGGISTGQDVIVRFAVK
HHHCCCCCCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCCEEECCCCCCEEEEEEEEC
PTSSILTPRATITKAGTPAEIITKGRHDPCVGIRAVPVGEAMMACVVLDHILLQRGQIGG
CCHHHCCCCHHEECCCCCHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCC
KVGETRGKIG
CCCCCCCCCC
>Mature Secondary Structure 
SMNSYGHLFRVTTWGESHGPALGATVDGCPPGIDVDAAAIQHWLDRRKPGQNKYTTQRR
CCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHH
EADEVEILSGVYEGQSTGTPIQLMIRNTDQRSKDYGDIAEKFRPGHADITYWQKYGIRDP
CCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCC
RGGGRSSARETAARVAAGGVARLALAALVPAVKITGYMVQMGPHGIDRECFDLAQVDENP
CCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHCCCCC
FWVPDAKAADEWAAYLDGLRKSGDSVGAVIEVRASGLPAGLGAPIYGKLDTDLAAAMMSI
CCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHH
NAVKGVEIGDGMAAAALTGSANADEIHMGDNGPEYSSNHAGGILGGISTGQDVIVRFAVK
HHHCCCCCCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCCEEECCCCCCEEEEEEEEC
PTSSILTPRATITKAGTPAEIITKGRHDPCVGIRAVPVGEAMMACVVLDHILLQRGQIGG
CCHHHCCCCHHEECCCCCHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCC
KVGETRGKIG
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA