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The map label for this gene is gap [H]

Identifier: 88657991

GI number: 88657991

Start: 8881

End: 9888

Strand: Direct

Name: gap [H]

Synonym: ECH_0011

Alternate gene names: 88657991

Gene position: 8881-9888 (Clockwise)

Preceding gene: 88658160

Following gene: 88657880

Centisome position: 0.76

GC content: 29.76

Gene sequence:

>1008_bases
ATGAAAATAGGAATAAATGGATTAGGTCGTATTGGAAGATGCTTAATAAGAGCCATATACGAAAATGAATTATTATATAA
ACACAAAATAGAATTATCTGCATTAAATGGATCTACATCACCAGAAACACATGCACATCTTATTCAATATGATTCTGTTC
ATGGAAAATTTCCACATAATGTAACATCAGAAGAAGGATATATAATAATAAATGATAAAAAAATCCCATTATCAACAGAA
AAAGAACCTAAAAGCATTCCTTGGGAAAAACATAACGTAGATATCGTACTAGAATGTACAGGAAAATTTAATAAAAAATC
TTTAGCAGAACAACATATAAACTCTACAGTAAAAAAAGTTTTAGTATCAGCACCCATGCAAGATTCTGATGCAACAATCG
TATATGGTGTAAATAATGAAATGCTAAAAAAAGAGCACAATATTATCTCAGCTGGATCATGCACAACAAACTGCATAGCA
CCTATTTTAAAAATCATGAATGATACTATAGGAATCAATAATGGATTTATGACAACTATACACTCATACACAAATGACCA
AAACTTAGTTGATAACAATCACAAAGATGTAAGAAGGGCAAGAGCATGCATGATGTCTATAATTCCTACTACAACAGGAG
CAACAAAAACTATTGATTTAATAATACCAGAATTAAAAGGAAAACTTAATGGAACCGCTGTACGTGTACCTACAGCAAAC
GTATCCATGGTAGACTTAGTTTTTAATTCCATTAAATCAACTACTGCTAATGAAATAAACGACATAATAAAAAATTCTTC
ACAAAACTCCAAAGTAATAAACATAACAGATAAGAAATTAGTATCTATAGACTTCTGTCACAGTACATATAGTTCAATAG
TAGATGCTGATGAAACATATGTTACCAATAATAATCTGTGTCGTATAGCAGCTTGGTATGACAATGAGTGGGCTTTTGCT
ATGAGAATGTTAGATATAGTATTACTATTATCAGAAAATCATATTTAA

Upstream 100 bases:

>100_bases
TGTTTACTCTCTGATAATATAAATATTTTTTAATATACTAAAAAAGGTATAAAAATGCAAAACATTATTATTAATTATTT
TATATAAAAAAAGAAAAAAT

Downstream 100 bases:

>100_bases
AAAATGTAGGTAAGGATTGTATTACTTAAGAAATTAAGATTATAACTATCTTTACCTATAAAATACCTGGCCACGAAAAC
ACATTTATAAGTACAAAGCA

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKIGINGLGRIGRCLIRAIYENELLYKHKIELSALNGSTSPETHAHLIQYDSVHGKFPHNVTSEEGYIIINDKKIPLSTE
KEPKSIPWEKHNVDIVLECTGKFNKKSLAEQHINSTVKKVLVSAPMQDSDATIVYGVNNEMLKKEHNIISAGSCTTNCIA
PILKIMNDTIGINNGFMTTIHSYTNDQNLVDNNHKDVRRARACMMSIIPTTTGATKTIDLIIPELKGKLNGTAVRVPTAN
VSMVDLVFNSIKSTTANEINDIIKNSSQNSKVINITDKKLVSIDFCHSTYSSIVDADETYVTNNNLCRIAAWYDNEWAFA
MRMLDIVLLLSENHI

Sequences:

>Translated_335_residues
MKIGINGLGRIGRCLIRAIYENELLYKHKIELSALNGSTSPETHAHLIQYDSVHGKFPHNVTSEEGYIIINDKKIPLSTE
KEPKSIPWEKHNVDIVLECTGKFNKKSLAEQHINSTVKKVLVSAPMQDSDATIVYGVNNEMLKKEHNIISAGSCTTNCIA
PILKIMNDTIGINNGFMTTIHSYTNDQNLVDNNHKDVRRARACMMSIIPTTTGATKTIDLIIPELKGKLNGTAVRVPTAN
VSMVDLVFNSIKSTTANEINDIIKNSSQNSKVINITDKKLVSIDFCHSTYSSIVDADETYVTNNNLCRIAAWYDNEWAFA
MRMLDIVLLLSENHI
>Mature_335_residues
MKIGINGLGRIGRCLIRAIYENELLYKHKIELSALNGSTSPETHAHLIQYDSVHGKFPHNVTSEEGYIIINDKKIPLSTE
KEPKSIPWEKHNVDIVLECTGKFNKKSLAEQHINSTVKKVLVSAPMQDSDATIVYGVNNEMLKKEHNIISAGSCTTNCIA
PILKIMNDTIGINNGFMTTIHSYTNDQNLVDNNHKDVRRARACMMSIIPTTTGATKTIDLIIPELKGKLNGTAVRVPTAN
VSMVDLVFNSIKSTTANEINDIIKNSSQNSKVINITDKKLVSIDFCHSTYSSIVDADETYVTNNNLCRIAAWYDNEWAFA
MRMLDIVLLLSENHI

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=331, Percent_Identity=38.0664652567976, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI7657116, Length=335, Percent_Identity=37.0149253731343, Blast_Score=236, Evalue=2e-62,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=41.0179640718563, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1788079, Length=335, Percent_Identity=38.2089552238806, Blast_Score=255, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17534677, Length=335, Percent_Identity=37.3134328358209, Blast_Score=229, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17534679, Length=335, Percent_Identity=37.3134328358209, Blast_Score=228, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI17568413, Length=341, Percent_Identity=38.1231671554252, Blast_Score=228, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI32566163, Length=341, Percent_Identity=38.1231671554252, Blast_Score=228, Evalue=5e-60,
Organism=Saccharomyces cerevisiae, GI6321631, Length=331, Percent_Identity=38.9728096676737, Blast_Score=257, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6322468, Length=331, Percent_Identity=38.6706948640483, Blast_Score=253, Evalue=4e-68,
Organism=Saccharomyces cerevisiae, GI6322409, Length=331, Percent_Identity=37.7643504531722, Blast_Score=247, Evalue=2e-66,
Organism=Drosophila melanogaster, GI19922412, Length=330, Percent_Identity=38.4848484848485, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI85725000, Length=330, Percent_Identity=37.2727272727273, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI22023983, Length=330, Percent_Identity=37.2727272727273, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI17933600, Length=330, Percent_Identity=36.6666666666667, Blast_Score=232, Evalue=3e-61,
Organism=Drosophila melanogaster, GI18110149, Length=330, Percent_Identity=36.6666666666667, Blast_Score=232, Evalue=3e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37315; Mature: 37315

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGINGLGRIGRCLIRAIYENELLYKHKIELSALNGSTSPETHAHLIQYDSVHGKFPHN
CEECCCHHHHHHHHHHHHHHHCCEEEEEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCC
VTSEEGYIIINDKKIPLSTEKEPKSIPWEKHNVDIVLECTGKFNKKSLAEQHINSTVKKV
CCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHH
LVSAPMQDSDATIVYGVNNEMLKKEHNIISAGSCTTNCIAPILKIMNDTIGINNGFMTTI
HHHCCCCCCCCEEEEECCHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEE
HSYTNDQNLVDNNHKDVRRARACMMSIIPTTTGATKTIDLIIPELKGKLNGTAVRVPTAN
ECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHCCCCCCCEEEECCCC
VSMVDLVFNSIKSTTANEINDIIKNSSQNSKVINITDKKLVSIDFCHSTYSSIVDADETY
CHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCEEEEEEEHHHHHHHHHCCCCEE
VTNNNLCRIAAWYDNEWAFAMRMLDIVLLLSENHI
EECCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKIGINGLGRIGRCLIRAIYENELLYKHKIELSALNGSTSPETHAHLIQYDSVHGKFPHN
CEECCCHHHHHHHHHHHHHHHCCEEEEEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCC
VTSEEGYIIINDKKIPLSTEKEPKSIPWEKHNVDIVLECTGKFNKKSLAEQHINSTVKKV
CCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHH
LVSAPMQDSDATIVYGVNNEMLKKEHNIISAGSCTTNCIAPILKIMNDTIGINNGFMTTI
HHHCCCCCCCCEEEEECCHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEE
HSYTNDQNLVDNNHKDVRRARACMMSIIPTTTGATKTIDLIIPELKGKLNGTAVRVPTAN
ECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHCCCCCCCEEEECCCC
VSMVDLVFNSIKSTTANEINDIIKNSSQNSKVINITDKKLVSIDFCHSTYSSIVDADETY
CHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCEEEEEEEHHHHHHHHHCCCCEE
VTNNNLCRIAAWYDNEWAFAMRMLDIVLLLSENHI
EECCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8045900; 10984043 [H]