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The map label for this gene is infC

Identifier: 88658160

GI number: 88658160

Start: 5609

End: 6130

Strand: Direct

Name: infC

Synonym: ECH_0007

Alternate gene names: 88658160

Gene position: 5609-6130 (Clockwise)

Preceding gene: 88657649

Following gene: 88657991

Centisome position: 0.48

GC content: 28.74

Gene sequence:

>522_bases
TTGAAAACAAAAAAGTTCTCTAATAAAAACAAGATTAATGAAATGATCACAGCAAAAAAAGTAAAGCTTGTTGATCAAAA
TAGTGTTATGATTGGAGTTGTAGACATTGAAGAAGCCTTATCTAGAGCTAAAGCTGTCAATTTAGACTTAGTTGAAATAG
TACATGATGATCAATATCCTTTATGTAAGATATTTGACTACAGTAAATATAGGTACAGCCATAAGAAGAAAATAAGCGAT
TCAAAAAAGAAACAAAAAACCATCATAGTAAAAGAACTTAAGTTTAAGCTTAATATTGGAGATAATGACTATAACGTAAA
ATTGAACATGTTACGTGGATTTATAGAAAGAGGTGATAAAGTAAAAATATCGCTAAGATTTATAGGAAGGGAAATACTTC
ATCCAGAAGTCGGAATGGAGATTATAGAAAGGTTAATAAGAGACACCGCTGATATTGCAAAACCTGAAAATTTACCAAAA
AAGGAAGGTAATATAATTAACATGGTATTAACTGCAAAATAA

Upstream 100 bases:

>100_bases
TTTAGAGTCCAATAAGCAGCACGTTATGCCTATTGATAAAGCGTTGAAAACATTATTAACTTGTGCTAGCATCTAGTAAA
TTTTAGTCAGGAGTGTAAGA

Downstream 100 bases:

>100_bases
AATTTTTATATAACTCCAGAGCATTATAGCATTTTTAAGTTGTAATGCTCTAACTTCCAAGAATTGGTTTGATTATTAAC
AATACTCACAGTGAAGTGAA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MKTKKFSNKNKINEMITAKKVKLVDQNSVMIGVVDIEEALSRAKAVNLDLVEIVHDDQYPLCKIFDYSKYRYSHKKKISD
SKKKQKTIIVKELKFKLNIGDNDYNVKLNMLRGFIERGDKVKISLRFIGREILHPEVGMEIIERLIRDTADIAKPENLPK
KEGNIINMVLTAK

Sequences:

>Translated_173_residues
MKTKKFSNKNKINEMITAKKVKLVDQNSVMIGVVDIEEALSRAKAVNLDLVEIVHDDQYPLCKIFDYSKYRYSHKKKISD
SKKKQKTIIVKELKFKLNIGDNDYNVKLNMLRGFIERGDKVKISLRFIGREILHPEVGMEIIERLIRDTADIAKPENLPK
KEGNIINMVLTAK
>Mature_173_residues
MKTKKFSNKNKINEMITAKKVKLVDQNSVMIGVVDIEEALSRAKAVNLDLVEIVHDDQYPLCKIFDYSKYRYSHKKKISD
SKKKQKTIIVKELKFKLNIGDNDYNVKLNMLRGFIERGDKVKISLRFIGREILHPEVGMEIIERLIRDTADIAKPENLPK
KEGNIINMVLTAK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=168, Percent_Identity=42.8571428571429, Blast_Score=124, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_EHRCR (Q2GI91)

Other databases:

- EMBL:   CP000236
- RefSeq:   YP_506842.1
- ProteinModelPortal:   Q2GI91
- STRING:   Q2GI91
- GeneID:   3927184
- GenomeReviews:   CP000236_GR
- KEGG:   ech:ECH_0007
- TIGR:   ECH_0007
- eggNOG:   COG0290
- HOGENOM:   HBG744268
- OMA:   FDRRAPV
- ProtClustDB:   PRK00028
- BioCyc:   ECHA205920:ECH_0007-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 20018; Mature: 20018

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKKFSNKNKINEMITAKKVKLVDQNSVMIGVVDIEEALSRAKAVNLDLVEIVHDDQYP
CCCCCCCCHHHHHHHHHHHHEEEEECCCEEEEEEEHHHHHHHHHHCCCEEEEEEECCCCC
LCKIFDYSKYRYSHKKKISDSKKKQKTIIVKELKFKLNIGDNDYNVKLNMLRGFIERGDK
EEEEEECHHHHHHHHHHCCCHHHHHHEEEEEEEEEEEEECCCCCEEEHHHHHHHHHCCCE
VKISLRFIGREILHPEVGMEIIERLIRDTADIAKPENLPKKEGNIINMVLTAK
EEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MKTKKFSNKNKINEMITAKKVKLVDQNSVMIGVVDIEEALSRAKAVNLDLVEIVHDDQYP
CCCCCCCCHHHHHHHHHHHHEEEEECCCEEEEEEEHHHHHHHHHHCCCEEEEEEECCCCC
LCKIFDYSKYRYSHKKKISDSKKKQKTIIVKELKFKLNIGDNDYNVKLNMLRGFIERGDK
EEEEEECHHHHHHHHHHCCCHHHHHHEEEEEEEEEEEEECCCCCEEEHHHHHHHHHCCCE
VKISLRFIGREILHPEVGMEIIERLIRDTADIAKPENLPKKEGNIINMVLTAK
EEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA