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The map label for this gene is gpmI

Identifier: 88608772

GI number: 88608772

Start: 795212

End: 796684

Strand: Direct

Name: gpmI

Synonym: NSE_0891

Alternate gene names: 88608772

Gene position: 795212-796684 (Clockwise)

Preceding gene: 88607963

Following gene: 88608152

Centisome position: 92.57

GC content: 42.36

Gene sequence:

>1473_bases
ATGCCTTTAATTTTGTGTATACTAGACGGCTGGGGTGTCTTACCCCAAGATGAATATAATGCTATCTACCAAGCTAGAAC
TCCGCACTATTGCACACTGTTAGAAAAGTTTCCACATTCACTTCTCTCTGCAAGTAGCCTAGAAGTAGGTTTGCCAGAGG
GGCAAATGGGTAATTCAGAAGTTGGTCACATGACGATAGGTAGTGGCAGAATTATATATCATGATCTTGTTCGAATTAAC
CGCGAGCTCGAAAAAATTGACAAAAACCCTCAGCTAAATGTCTTTGCAAATAAACTCAAAGGAAAGAGGTGTCATCTTGT
TGGACTCTTATCTGATGGAGGAGTACACTCTCACGTCGCACATATAAACAAAATCTCGAACTACCTCACATCGCGTGGAG
TAGCTGTATGCATACACGCATTCCTAGATGGTCGTGACACAGCACCAAAAGCAGCGAAGCGATATATCACAGAAGAGAAC
ACAAGAAGAATTGCGACTCTGGCTGGGCGCTACTATGGTATGGACAGAGATAAAAATTGGGACCGAACAGTCGAAGCGTA
TCGTGTTATTGTGAAACCATCAAAGCAGCAAAGAATCTTCGAAAAAGCAGATGAGGCCATAGAATATTACTATTCTCAGG
GCATAAGCGACGAGTTCATTCCACCATCAGTGATTGGTGACTATGAAGGTGCACAAGATGGGGACGGACTTTTTATAGCA
AATTTCCGTCCGGATAGAGCAAGACAAATCACCTCTGAGCTTATTGGTAAAACAAGCTTCTGCAAAGACAAGATAAAATT
CTCAGAAATGATGACAATGAGCCAGTACTTTGAAGAATCCTTACCATCATTAATCCTACGACAGCAGATTAAGAATACTC
TATCGGAGATCATCTCAGGTGCCGGAATGCACCAGCTCAAAATAGCGGAGACCGAAAAATATGCTCATGTGAGTTACTTC
TTCAATGGAGGAAAAGAAGCAGCTTTTGCAAGAGAAGAGCGTATTCTGATAAACTCGCCACGCGTAAAGACGTATGATTT
GGAACCAAAAATGGCAGCCTTAGAAGTAACTGATGCCCTTATCAAGGCAATAAAGTCAAAAAGATTTGATTTCATTGTGG
TCAACTACGCAAACGCCGATATGGTAGGCCACACCGGAAACTTGTCAGCAACTATCGAGGCAATAGAGACACTAGATAAT
TGCCTTGGCAAACTATACAAAGAGGCCTGTGAACTTAATGGGTACGAAATGATAGTTACCTCAGATCATGGTAACGCAGA
ATGTATGTACGACCATTCTACAAAGCTTTCAAACACAGCTCACACAACGAACCCAGTACCATTCATCGTAGCGTCACAGA
GGGTGAAGCATGTAAACAACGGAGGCCTATATAATATCGCTGGGACTGTCCTCAAGCTTCTCGGTATAGAGAAGCCAACA
GAACTAGCTAATGACCTTATTTGCTTCGAGTAA

Upstream 100 bases:

>100_bases
ACTGTGAAAATATAATGCAAGAATTCGAGTGATATGTTACAATCCGCCCGGGTGTTTCAACTGCACCGGGTTGGACCTTT
TGTTCGCTTGATCCCAGTAA

Downstream 100 bases:

>100_bases
TCGACACGGAACCCCTAAACCTGTTCTTCAACTAGGATCCGCTCCTCAATATCAGTGTCATGATAGATCTCTTCCTCTTC
GTACGGTACACGTACTGAAG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM [H]

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MPLILCILDGWGVLPQDEYNAIYQARTPHYCTLLEKFPHSLLSASSLEVGLPEGQMGNSEVGHMTIGSGRIIYHDLVRIN
RELEKIDKNPQLNVFANKLKGKRCHLVGLLSDGGVHSHVAHINKISNYLTSRGVAVCIHAFLDGRDTAPKAAKRYITEEN
TRRIATLAGRYYGMDRDKNWDRTVEAYRVIVKPSKQQRIFEKADEAIEYYYSQGISDEFIPPSVIGDYEGAQDGDGLFIA
NFRPDRARQITSELIGKTSFCKDKIKFSEMMTMSQYFEESLPSLILRQQIKNTLSEIISGAGMHQLKIAETEKYAHVSYF
FNGGKEAAFAREERILINSPRVKTYDLEPKMAALEVTDALIKAIKSKRFDFIVVNYANADMVGHTGNLSATIEAIETLDN
CLGKLYKEACELNGYEMIVTSDHGNAECMYDHSTKLSNTAHTTNPVPFIVASQRVKHVNNGGLYNIAGTVLKLLGIEKPT
ELANDLICFE

Sequences:

>Translated_490_residues
MPLILCILDGWGVLPQDEYNAIYQARTPHYCTLLEKFPHSLLSASSLEVGLPEGQMGNSEVGHMTIGSGRIIYHDLVRIN
RELEKIDKNPQLNVFANKLKGKRCHLVGLLSDGGVHSHVAHINKISNYLTSRGVAVCIHAFLDGRDTAPKAAKRYITEEN
TRRIATLAGRYYGMDRDKNWDRTVEAYRVIVKPSKQQRIFEKADEAIEYYYSQGISDEFIPPSVIGDYEGAQDGDGLFIA
NFRPDRARQITSELIGKTSFCKDKIKFSEMMTMSQYFEESLPSLILRQQIKNTLSEIISGAGMHQLKIAETEKYAHVSYF
FNGGKEAAFAREERILINSPRVKTYDLEPKMAALEVTDALIKAIKSKRFDFIVVNYANADMVGHTGNLSATIEAIETLDN
CLGKLYKEACELNGYEMIVTSDHGNAECMYDHSTKLSNTAHTTNPVPFIVASQRVKHVNNGGLYNIAGTVLKLLGIEKPT
ELANDLICFE
>Mature_489_residues
PLILCILDGWGVLPQDEYNAIYQARTPHYCTLLEKFPHSLLSASSLEVGLPEGQMGNSEVGHMTIGSGRIIYHDLVRINR
ELEKIDKNPQLNVFANKLKGKRCHLVGLLSDGGVHSHVAHINKISNYLTSRGVAVCIHAFLDGRDTAPKAAKRYITEENT
RRIATLAGRYYGMDRDKNWDRTVEAYRVIVKPSKQQRIFEKADEAIEYYYSQGISDEFIPPSVIGDYEGAQDGDGLFIAN
FRPDRARQITSELIGKTSFCKDKIKFSEMMTMSQYFEESLPSLILRQQIKNTLSEIISGAGMHQLKIAETEKYAHVSYFF
NGGKEAAFAREERILINSPRVKTYDLEPKMAALEVTDALIKAIKSKRFDFIVVNYANADMVGHTGNLSATIEAIETLDNC
LGKLYKEACELNGYEMIVTSDHGNAECMYDHSTKLSNTAHTTNPVPFIVASQRVKHVNNGGLYNIAGTVLKLLGIEKPTE
LANDLICFE

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1790041, Length=501, Percent_Identity=42.7145708582834, Blast_Score=397, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI32564249, Length=506, Percent_Identity=37.3517786561265, Blast_Score=311, Evalue=7e-85,
Organism=Caenorhabditis elegans, GI17507741, Length=506, Percent_Identity=37.3517786561265, Blast_Score=310, Evalue=1e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995 [H]

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 54875; Mature: 54744

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLILCILDGWGVLPQDEYNAIYQARTPHYCTLLEKFPHSLLSASSLEVGLPEGQMGNSE
CCEEEEEECCCCCCCCCHHHHHEECCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCC
VGHMTIGSGRIIYHDLVRINRELEKIDKNPQLNVFANKLKGKRCHLVGLLSDGGVHSHVA
CCEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHCCCCEEEEEEEECCCCHHHHHH
HINKISNYLTSRGVAVCIHAFLDGRDTAPKAAKRYITEENTRRIATLAGRYYGMDRDKNW
HHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCH
DRTVEAYRVIVKPSKQQRIFEKADEAIEYYYSQGISDEFIPPSVIGDYEGAQDGDGLFIA
HHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCEEEE
NFRPDRARQITSELIGKTSFCKDKIKFSEMMTMSQYFEESLPSLILRQQIKNTLSEIISG
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AGMHQLKIAETEKYAHVSYFFNGGKEAAFAREERILINSPRVKTYDLEPKMAALEVTDAL
CCCCEEEEECCCCEEEEEEEECCCCCCHHHHCCEEEEECCCEEEEECCCCHHHHHHHHHH
IKAIKSKRFDFIVVNYANADMVGHTGNLSATIEAIETLDNCLGKLYKEACELNGYEMIVT
HHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
SDHGNAECMYDHSTKLSNTAHTTNPVPFIVASQRVKHVNNGGLYNIAGTVLKLLGIEKPT
CCCCCEEEEEECCCCCCCCCCCCCCCEEEEECHHHHHCCCCCEEHHHHHHHHHHCCCCCH
ELANDLICFE
HHHCCCCCCC
>Mature Secondary Structure 
PLILCILDGWGVLPQDEYNAIYQARTPHYCTLLEKFPHSLLSASSLEVGLPEGQMGNSE
CEEEEEECCCCCCCCCHHHHHEECCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCC
VGHMTIGSGRIIYHDLVRINRELEKIDKNPQLNVFANKLKGKRCHLVGLLSDGGVHSHVA
CCEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHCCCCEEEEEEEECCCCHHHHHH
HINKISNYLTSRGVAVCIHAFLDGRDTAPKAAKRYITEENTRRIATLAGRYYGMDRDKNW
HHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCH
DRTVEAYRVIVKPSKQQRIFEKADEAIEYYYSQGISDEFIPPSVIGDYEGAQDGDGLFIA
HHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCEEEE
NFRPDRARQITSELIGKTSFCKDKIKFSEMMTMSQYFEESLPSLILRQQIKNTLSEIISG
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AGMHQLKIAETEKYAHVSYFFNGGKEAAFAREERILINSPRVKTYDLEPKMAALEVTDAL
CCCCEEEEECCCCEEEEEEEECCCCCCHHHHCCEEEEECCCEEEEECCCCHHHHHHHHHH
IKAIKSKRFDFIVVNYANADMVGHTGNLSATIEAIETLDNCLGKLYKEACELNGYEMIVT
HHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
SDHGNAECMYDHSTKLSNTAHTTNPVPFIVASQRVKHVNNGGLYNIAGTVLKLLGIEKPT
CCCCCEEEEEECCCCCCCCCCCCCCCEEEEECHHHHHCCCCCEEHHHHHHHHHHCCCCCH
ELANDLICFE
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA