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The map label for this gene is comF [H]

Identifier: 88608634

GI number: 88608634

Start: 340113

End: 340925

Strand: Reverse

Name: comF [H]

Synonym: NSE_0416

Alternate gene names: 88608634

Gene position: 340925-340113 (Counterclockwise)

Preceding gene: 88608603

Following gene: 88608409

Centisome position: 39.69

GC content: 36.41

Gene sequence:

>813_bases
ATGAAACTATTTAGTGAACGGTTTTTAGTTCTTTTGAGCAATCTATACAAAAATCGACGATTTATCTTCAAGCAAAATAG
CTTTAGCAAAACCCTGAGACTAATCAAATCCACTTTTAAAAGCTTTCTCACATTCCTCTTCCCTGATTGCTGCATAATCT
GCTCCAGTGAAGAAGAGCTAGTAGAACATTGTATGTGCAAGCCTTGTAGAAACGAAGTTCATCTCTTGAAAGATCACTTA
CACTGTTACTGTTGTGGTAAGAAAATGAAGACTTCGAATTTATGCATCACATGTGCTGCATCGAAACCTAAGTTTAACGA
AGCAAAAGCTGTATTTGTTTACAATGCTTATGTTTCAGTGTTCATGCAAAAAATCAAATTTCATGATGGGACATTCATAA
CAAAATCTTTGGCAAAAATGATCCTAGGGCATTTTAAAGAAGATCTCGAAAAGTGTGATTTTATCATACCAGTACCGATA
CATCGCGTTAGATTGTTTCGAAGACAGTACAATCAAGTAGCATTGATCGCTATGCAACTGGCAAAGTTGATACACGTGAA
AGTACGATTAGATGTCCTCCACAAAATAAAGAACACACCATCACAACTTAATCTTTCTACACATCAACGAAAAACAAGTC
TACAGGATGTGTTCACAGTAGGAAACCAAGCTGGAATCAAGGACGCATCTATCATCTTACTTGATGACGTTATAACTACG
GGTACTACAGTTTCACGTTGTGCAGATGCACTTTCAAAATACAATCCCAAGAAAATAGTGGTCATTGCTATAGCAAGATC
GATCCTGTATTAG

Upstream 100 bases:

>100_bases
CCCATTTTCAATGCAATCAGCCAAAATAGGCTTTTCCTTTACACTAATCACTCTAATACTAAAGAAGGGCTTTAAAAGGC
TTGCATCACTATCATGAACC

Downstream 100 bases:

>100_bases
CGAATGCCCAAAAGATGAAGAGTTTCCACTCACCCCGAAAAAATCACTCATTGATAACAGAAAAGTTCAGCCTGCTTGCT
CCATATAAGAACAAACCGTA

Product: putative competence protein F

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MKLFSERFLVLLSNLYKNRRFIFKQNSFSKTLRLIKSTFKSFLTFLFPDCCIICSSEEELVEHCMCKPCRNEVHLLKDHL
HCYCCGKKMKTSNLCITCAASKPKFNEAKAVFVYNAYVSVFMQKIKFHDGTFITKSLAKMILGHFKEDLEKCDFIIPVPI
HRVRLFRRQYNQVALIAMQLAKLIHVKVRLDVLHKIKNTPSQLNLSTHQRKTSLQDVFTVGNQAGIKDASIILLDDVITT
GTTVSRCADALSKYNPKKIVVIAIARSILY

Sequences:

>Translated_270_residues
MKLFSERFLVLLSNLYKNRRFIFKQNSFSKTLRLIKSTFKSFLTFLFPDCCIICSSEEELVEHCMCKPCRNEVHLLKDHL
HCYCCGKKMKTSNLCITCAASKPKFNEAKAVFVYNAYVSVFMQKIKFHDGTFITKSLAKMILGHFKEDLEKCDFIIPVPI
HRVRLFRRQYNQVALIAMQLAKLIHVKVRLDVLHKIKNTPSQLNLSTHQRKTSLQDVFTVGNQAGIKDASIILLDDVITT
GTTVSRCADALSKYNPKKIVVIAIARSILY
>Mature_270_residues
MKLFSERFLVLLSNLYKNRRFIFKQNSFSKTLRLIKSTFKSFLTFLFPDCCIICSSEEELVEHCMCKPCRNEVHLLKDHL
HCYCCGKKMKTSNLCITCAASKPKFNEAKAVFVYNAYVSVFMQKIKFHDGTFITKSLAKMILGHFKEDLEKCDFIIPVPI
HRVRLFRRQYNQVALIAMQLAKLIHVKVRLDVLHKIKNTPSQLNLSTHQRKTSLQDVFTVGNQAGIKDASIILLDDVITT
GTTVSRCADALSKYNPKKIVVIAIARSILY

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=227, Percent_Identity=24.6696035242291, Blast_Score=71, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 31034; Mature: 31034

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFSERFLVLLSNLYKNRRFIFKQNSFSKTLRLIKSTFKSFLTFLFPDCCIICSSEEEL
CCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHH
VEHCMCKPCRNEVHLLKDHLHCYCCGKKMKTSNLCITCAASKPKFNEAKAVFVYNAYVSV
HHHHCCCCCHHHHHHHHHHHEEEECCCCCCCCCEEEEEECCCCCCCCCCEEEEHHHHHHH
FMQKIKFHDGTFITKSLAKMILGHFKEDLEKCDFIIPVPIHRVRLFRRQYNQVALIAMQL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHH
AKLIHVKVRLDVLHKIKNTPSQLNLSTHQRKTSLQDVFTVGNQAGIKDASIILLDDVITT
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHHC
GTTVSRCADALSKYNPKKIVVIAIARSILY
CCHHHHHHHHHHHCCCCEEEEHHHHHHHCC
>Mature Secondary Structure
MKLFSERFLVLLSNLYKNRRFIFKQNSFSKTLRLIKSTFKSFLTFLFPDCCIICSSEEEL
CCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHH
VEHCMCKPCRNEVHLLKDHLHCYCCGKKMKTSNLCITCAASKPKFNEAKAVFVYNAYVSV
HHHHCCCCCHHHHHHHHHHHEEEECCCCCCCCCEEEEEECCCCCCCCCCEEEEHHHHHHH
FMQKIKFHDGTFITKSLAKMILGHFKEDLEKCDFIIPVPIHRVRLFRRQYNQVALIAMQL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHH
AKLIHVKVRLDVLHKIKNTPSQLNLSTHQRKTSLQDVFTVGNQAGIKDASIILLDDVITT
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHHC
GTTVSRCADALSKYNPKKIVVIAIARSILY
CCHHHHHHHHHHHCCCCEEEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]