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The map label for this gene is sucC

Identifier: 88608589

GI number: 88608589

Start: 213069

End: 214247

Strand: Reverse

Name: sucC

Synonym: NSE_0251

Alternate gene names: 88608589

Gene position: 214247-213069 (Counterclockwise)

Preceding gene: 88608166

Following gene: 88608406

Centisome position: 24.94

GC content: 43.26

Gene sequence:

>1179_bases
ATGAACATTCATGAATACCAAGCAAAGGAGATACTGCGAGTCTGTGGTGTGCCCACGCCCGCCGGGTTTTTGGTTCAAGA
GGATACAGAAACCTCAGAAATCGCAAAAAGTTTAGCTCGACTGGGTGGCAAGGTATTTGCAGTGAAAGCTCAAATACATG
CAGGTGGAAGAGGTAAAGCTGGTGGTGTCGTGATTTGTCGTTCTGTTGAAGAGGCGATAGATAACACAAAAAAAATGCTT
GGTATGAACCTGGTAACTCATCAAACTTCTCCAGCGGGACAGAAAGTACGGAAGGTCTATATTGAGGCTGGACAGTCGAT
CCTGAAAGAATACTACCTAAGCATGGTGGTTGATAGAGAAAACGCGAAAGTGGCCATAATTGCCTCAGAAGAAGGGGGAA
TGGACATAGAAGAAATTGCGAGATCGACCCCAGAAAAAATCAAGAAAGTCTTTGTAGATCTAAGTATTGGTATATCAGAC
TTTCACGCAAGGAAAATAGGATTTGAGCTAGGACTCAGTCTTGCTCAAATTAAGCAGTTCACACCACTTGTGAAGAAATT
GTATGCTCTATTCGTCACAAGGGATGCCTCTCAAGTCGAAATAAACCCCTTGATAGCAAATAGTAAAGGTGAGTTCATAG
CGTTAGATGCAAAACTTAACTTCGACGATAATGCGCTTTATCGCCACCCAGATACGCTAGAACTAAGAGATTTATACGAA
GAGGACCCAAAAGAAATTGAGGCGGCAAAATACAATCTCAACTACATCAAAATGGAAGGCGGCATAGGTTGTATGGTAAA
CGGAGCTGGGCTCGCGATGGCAACAATGGACATCATAAAATATTATGGTGCTAGTCCAGCGAATTTCCTAGATGTTGGTG
GTGGGGCCAACCTAGAGCAAGTCACGAACGCATTTAAAATAATTTCATCTGACAAACATGTCGCCGGCATATTAGTGAAC
ATTTTCGGTGGTATCATGCGTTGTGATATCATCGCGGAGGGTATAGTTGCAGCAGCCAAAGATATAGGTCTTACTATGCC
TTTAGTCGTCCGCCTATCCGGCACTAACTACTCTGCTGGAATAAAGATTATTGAGGGCTCCGGACTGAATATTGTGACCG
CCTCCGAACTTGATGATGCGGCACAAAAAATCGTAAAACTGACAAGGAAGGAAATTTAA

Upstream 100 bases:

>100_bases
AAGCAAAGTTGTTACATCAGCAGTCTAGGTTGTTTGGGGAAATCTTACGTGCTAAAAGGTACTCAGCTGTGTAAGAAAAT
CTTTCAGGATAAGCAAACAA

Downstream 100 bases:

>100_bases
TGGCGATTTTAGTTAACAAAGAAACACGGGTTATCTGCCAAGGATTTACAGGCCATCAGGGTACTTTTCATTCTGAACAG
GCTATTGAATACGGCACAAA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MNIHEYQAKEILRVCGVPTPAGFLVQEDTETSEIAKSLARLGGKVFAVKAQIHAGGRGKAGGVVICRSVEEAIDNTKKML
GMNLVTHQTSPAGQKVRKVYIEAGQSILKEYYLSMVVDRENAKVAIIASEEGGMDIEEIARSTPEKIKKVFVDLSIGISD
FHARKIGFELGLSLAQIKQFTPLVKKLYALFVTRDASQVEINPLIANSKGEFIALDAKLNFDDNALYRHPDTLELRDLYE
EDPKEIEAAKYNLNYIKMEGGIGCMVNGAGLAMATMDIIKYYGASPANFLDVGGGANLEQVTNAFKIISSDKHVAGILVN
IFGGIMRCDIIAEGIVAAAKDIGLTMPLVVRLSGTNYSAGIKIIEGSGLNIVTASELDDAAQKIVKLTRKEI

Sequences:

>Translated_392_residues
MNIHEYQAKEILRVCGVPTPAGFLVQEDTETSEIAKSLARLGGKVFAVKAQIHAGGRGKAGGVVICRSVEEAIDNTKKML
GMNLVTHQTSPAGQKVRKVYIEAGQSILKEYYLSMVVDRENAKVAIIASEEGGMDIEEIARSTPEKIKKVFVDLSIGISD
FHARKIGFELGLSLAQIKQFTPLVKKLYALFVTRDASQVEINPLIANSKGEFIALDAKLNFDDNALYRHPDTLELRDLYE
EDPKEIEAAKYNLNYIKMEGGIGCMVNGAGLAMATMDIIKYYGASPANFLDVGGGANLEQVTNAFKIISSDKHVAGILVN
IFGGIMRCDIIAEGIVAAAKDIGLTMPLVVRLSGTNYSAGIKIIEGSGLNIVTASELDDAAQKIVKLTRKEI
>Mature_392_residues
MNIHEYQAKEILRVCGVPTPAGFLVQEDTETSEIAKSLARLGGKVFAVKAQIHAGGRGKAGGVVICRSVEEAIDNTKKML
GMNLVTHQTSPAGQKVRKVYIEAGQSILKEYYLSMVVDRENAKVAIIASEEGGMDIEEIARSTPEKIKKVFVDLSIGISD
FHARKIGFELGLSLAQIKQFTPLVKKLYALFVTRDASQVEINPLIANSKGEFIALDAKLNFDDNALYRHPDTLELRDLYE
EDPKEIEAAKYNLNYIKMEGGIGCMVNGAGLAMATMDIIKYYGASPANFLDVGGGANLEQVTNAFKIISSDKHVAGILVN
IFGGIMRCDIIAEGIVAAAKDIGLTMPLVVRLSGTNYSAGIKIIEGSGLNIVTASELDDAAQKIVKLTRKEI

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=395, Percent_Identity=44.8101265822785, Blast_Score=337, Evalue=9e-93,
Organism=Homo sapiens, GI157779135, Length=386, Percent_Identity=44.559585492228, Blast_Score=305, Evalue=4e-83,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=44.7513812154696, Blast_Score=289, Evalue=4e-78,
Organism=Escherichia coli, GI1786948, Length=385, Percent_Identity=49.3506493506493, Blast_Score=371, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=44.9238578680203, Blast_Score=334, Evalue=6e-92,
Organism=Caenorhabditis elegans, GI17567829, Length=394, Percent_Identity=45.4314720812183, Blast_Score=329, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6321683, Length=399, Percent_Identity=45.3634085213033, Blast_Score=333, Evalue=3e-92,
Organism=Drosophila melanogaster, GI21356231, Length=394, Percent_Identity=47.9695431472081, Blast_Score=340, Evalue=1e-93,
Organism=Drosophila melanogaster, GI161078106, Length=403, Percent_Identity=46.6501240694789, Blast_Score=337, Evalue=1e-92,
Organism=Drosophila melanogaster, GI24645208, Length=403, Percent_Identity=46.6501240694789, Blast_Score=337, Evalue=1e-92,
Organism=Drosophila melanogaster, GI281361397, Length=404, Percent_Identity=46.7821782178218, Blast_Score=335, Evalue=4e-92,
Organism=Drosophila melanogaster, GI281361395, Length=404, Percent_Identity=46.7821782178218, Blast_Score=335, Evalue=4e-92,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_NEOSM (Q2GEF1)

Other databases:

- EMBL:   CP000237
- RefSeq:   YP_506145.1
- HSSP:   P53590
- ProteinModelPortal:   Q2GEF1
- SMR:   Q2GEF1
- STRING:   Q2GEF1
- GeneID:   3931912
- GenomeReviews:   CP000237_GR
- KEGG:   nse:NSE_0251
- TIGR:   NSE_0251
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   EGDIGCM
- PhylomeDB:   Q2GEF1
- ProtClustDB:   CLSK2528012
- BioCyc:   NSEN222891:NSE_0251-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 42411; Mature: 42411

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKEILRVCGVPTPAGFLVQEDTETSEIAKSLARLGGKVFAVKAQIHAGGRGKA
CCCHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHCCCEEEEEEEEEECCCCCCC
GGVVICRSVEEAIDNTKKMLGMNLVTHQTSPAGQKVRKVYIEAGQSILKEYYLSMVVDRE
CCEEEEECHHHHHHHHHHHHCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECC
NAKVAIIASEEGGMDIEEIARSTPEKIKKVFVDLSIGISDFHARKIGFELGLSLAQIKQF
CCEEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHH
TPLVKKLYALFVTRDASQVEINPLIANSKGEFIALDAKLNFDDNALYRHPDTLELRDLYE
HHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEEEEECCCCCCEECCCCCCHHHHHHC
EDPKEIEAAKYNLNYIKMEGGIGCMVNGAGLAMATMDIIKYYGASPANFLDVGGGANLEQ
CCHHHHHHHEECCEEEEECCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHH
VTNAFKIISSDKHVAGILVNIFGGIMRCDIIAEGIVAAAKDIGLTMPLVVRLSGTNYSAG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCC
IKIIEGSGLNIVTASELDDAAQKIVKLTRKEI
EEEEECCCCEEEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKEILRVCGVPTPAGFLVQEDTETSEIAKSLARLGGKVFAVKAQIHAGGRGKA
CCCHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHCCCEEEEEEEEEECCCCCCC
GGVVICRSVEEAIDNTKKMLGMNLVTHQTSPAGQKVRKVYIEAGQSILKEYYLSMVVDRE
CCEEEEECHHHHHHHHHHHHCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECC
NAKVAIIASEEGGMDIEEIARSTPEKIKKVFVDLSIGISDFHARKIGFELGLSLAQIKQF
CCEEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHH
TPLVKKLYALFVTRDASQVEINPLIANSKGEFIALDAKLNFDDNALYRHPDTLELRDLYE
HHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEEEEECCCCCCEECCCCCCHHHHHHC
EDPKEIEAAKYNLNYIKMEGGIGCMVNGAGLAMATMDIIKYYGASPANFLDVGGGANLEQ
CCHHHHHHHEECCEEEEECCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHH
VTNAFKIISSDKHVAGILVNIFGGIMRCDIIAEGIVAAAKDIGLTMPLVVRLSGTNYSAG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCC
IKIIEGSGLNIVTASELDDAAQKIVKLTRKEI
EEEEECCCCEEEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA