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The map label for this gene is oxaA [H]

Identifier: 88608477

GI number: 88608477

Start: 326227

End: 327927

Strand: Reverse

Name: oxaA [H]

Synonym: NSE_0402

Alternate gene names: 88608477

Gene position: 327927-326227 (Counterclockwise)

Preceding gene: 88608409

Following gene: 88608667

Centisome position: 38.18

GC content: 40.27

Gene sequence:

>1701_bases
ATGCAGCAGACATACAACGTTTTCATAGCAACTCTGTTGTCGTTTCTCGTGATCATCGGGTGGAACCTCGTGTTCTATAA
TCCCACACAAAGAGAGAGCTTTCATGAAGTCCAAAAAAAAGAAAGCGTCAAAGTATATGAGTCTTTGGAAAGCACCCTGA
GTACAGAACGAATCAAAATTAGCAGCAGCAAGCTCGAGGGAAGTATCCAGTTAACTGGCCTTGCTCTCGATGATCTGATC
CTAAAAGATTACAAATCTGATGACCTAAAAGATCAGTATCGCCTTCTTTATCCGAACAAGACAAAAGGTGCATATTTCAT
TAATCCAGGCTGGACAATACCCGGTGATCCTGGCCTTAGGACTCCCTCTTCCAAAACCAAATGGCAGGCTGATTCTGAAC
TTTTAACTCCTGGCAGTCCAGTAACTTTTTCTTGGGACAACGGGTTTGGTCTGCTTTTTAAAGTGGTTGTGAGTATCGAT
GATAATTACATGTTTACCTTCAAGCAAATCGTTGAGAACAAGTCGCAAAACGATCTAAGTGTCGGCTCACACTTTACAAT
CACCAAGAGTCTCCCTGAAACAAATAAAAGCATGCTTATAATGCATGAGGGGCCCGTAGGAGTAGTAAAAGATCAGCTAA
TGGAGCTCAAGTACTCTAAAATAGCAAAAAAGAACAAGAGTATAGCATTTGACGAAGACACCCAGAATCAACGGGGATGG
TTTGGCTTTTCAGACAAGTATTGGTTTGTCTCGCAGATTTTCGAGAACTCATCAGACGGGAAGGTGTATATCAGTCACAT
TGATGATAAAAGCGATGACATCTTCCGCATTACAAATTTTAACGCACAGAAAATAGTCCGTGGTGGTGGCCTTATTGTAA
AGGAAACTATGCTCTTCGCAGGGCCCAAGAAGCTATCTCTCTTAGAAGAATACGCACAGAACATGAGAATCTATCTCTTT
GATAGAGCCGTAGATTTTGGTGTTTTGTATTTTATAACGAAACCCATTTCAAAATTGTTACAGGTTTTCCATCACCTCGT
TGGGAATTTCGGTGTTGCAATTATACTGTTGACTTTCTTCATCAGGGTACTAATGTTGCCACTATCAATTAAATCTGGTA
TCTCGATGTTCAAGATCAAGGAGTTGCAACCTGAAATCCTTAAGATCAAATCGATGTACCAAAATGATAAGGATGCGCTA
AACAGAGCGAGTGTCGAGTTGTTTAGAAAGCATAGAGTCACACCGATGTCAGGCTGTTTGCCAACTCTGTTGCAAGTCCC
GGTGTTTTTTGCACTCTACAAGGTAATCTTTATAACTGTAGAAATGCGGCAGGCGCCGTTTTTTCTATGGATTTCTGATC
TCTCGCTGCCAGATCCAACAAATTTGTTTACTCTATTCGGTTTAATTGATTGGAACTGTCCCGATTTTCTTTCAATAGGA
ATACTACCTATAATACTCGGATTAACCATGGTCATTCAACAAAAGCTTAGCCCATCACACTATGACGACGGCACACAGGC
TTTTATGATTAAAGCTATGCCGTATGTTTTCATGATATTGTTCGCGAGCTTTCCTTCAGGTTTAGTTCTTTATTGGGTAT
TTAATAACGTTCTCTCACTACTGCAACAGTTCGTGATAGGTAAATACCTATTTACTAAAAAGTTTAAAGCTATGACAAAA
ACTCAAGAAAGCCTCCCTTGA

Upstream 100 bases:

>100_bases
CCACTCTCGGGAATAGTCTACTATATAGCGAGAAAGTTTCTAGATGTCGAGTATTTTTGTGCTATCATCACTACTTGAAC
ATCATTCATCAAAGCTCTTA

Downstream 100 bases:

>100_bases
GTCAATTTTAACATTATGGATCTCTAATAAACACGTTAGCGTTGCCTACCTTGTTATAAGATTACTTTCCCCTTACGGTG
TTTTTGATGTTTATTCCTCC

Product: inner membrane protein, 60 kDa

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MQQTYNVFIATLLSFLVIIGWNLVFYNPTQRESFHEVQKKESVKVYESLESTLSTERIKISSSKLEGSIQLTGLALDDLI
LKDYKSDDLKDQYRLLYPNKTKGAYFINPGWTIPGDPGLRTPSSKTKWQADSELLTPGSPVTFSWDNGFGLLFKVVVSID
DNYMFTFKQIVENKSQNDLSVGSHFTITKSLPETNKSMLIMHEGPVGVVKDQLMELKYSKIAKKNKSIAFDEDTQNQRGW
FGFSDKYWFVSQIFENSSDGKVYISHIDDKSDDIFRITNFNAQKIVRGGGLIVKETMLFAGPKKLSLLEEYAQNMRIYLF
DRAVDFGVLYFITKPISKLLQVFHHLVGNFGVAIILLTFFIRVLMLPLSIKSGISMFKIKELQPEILKIKSMYQNDKDAL
NRASVELFRKHRVTPMSGCLPTLLQVPVFFALYKVIFITVEMRQAPFFLWISDLSLPDPTNLFTLFGLIDWNCPDFLSIG
ILPIILGLTMVIQQKLSPSHYDDGTQAFMIKAMPYVFMILFASFPSGLVLYWVFNNVLSLLQQFVIGKYLFTKKFKAMTK
TQESLP

Sequences:

>Translated_566_residues
MQQTYNVFIATLLSFLVIIGWNLVFYNPTQRESFHEVQKKESVKVYESLESTLSTERIKISSSKLEGSIQLTGLALDDLI
LKDYKSDDLKDQYRLLYPNKTKGAYFINPGWTIPGDPGLRTPSSKTKWQADSELLTPGSPVTFSWDNGFGLLFKVVVSID
DNYMFTFKQIVENKSQNDLSVGSHFTITKSLPETNKSMLIMHEGPVGVVKDQLMELKYSKIAKKNKSIAFDEDTQNQRGW
FGFSDKYWFVSQIFENSSDGKVYISHIDDKSDDIFRITNFNAQKIVRGGGLIVKETMLFAGPKKLSLLEEYAQNMRIYLF
DRAVDFGVLYFITKPISKLLQVFHHLVGNFGVAIILLTFFIRVLMLPLSIKSGISMFKIKELQPEILKIKSMYQNDKDAL
NRASVELFRKHRVTPMSGCLPTLLQVPVFFALYKVIFITVEMRQAPFFLWISDLSLPDPTNLFTLFGLIDWNCPDFLSIG
ILPIILGLTMVIQQKLSPSHYDDGTQAFMIKAMPYVFMILFASFPSGLVLYWVFNNVLSLLQQFVIGKYLFTKKFKAMTK
TQESLP
>Mature_566_residues
MQQTYNVFIATLLSFLVIIGWNLVFYNPTQRESFHEVQKKESVKVYESLESTLSTERIKISSSKLEGSIQLTGLALDDLI
LKDYKSDDLKDQYRLLYPNKTKGAYFINPGWTIPGDPGLRTPSSKTKWQADSELLTPGSPVTFSWDNGFGLLFKVVVSID
DNYMFTFKQIVENKSQNDLSVGSHFTITKSLPETNKSMLIMHEGPVGVVKDQLMELKYSKIAKKNKSIAFDEDTQNQRGW
FGFSDKYWFVSQIFENSSDGKVYISHIDDKSDDIFRITNFNAQKIVRGGGLIVKETMLFAGPKKLSLLEEYAQNMRIYLF
DRAVDFGVLYFITKPISKLLQVFHHLVGNFGVAIILLTFFIRVLMLPLSIKSGISMFKIKELQPEILKIKSMYQNDKDAL
NRASVELFRKHRVTPMSGCLPTLLQVPVFFALYKVIFITVEMRQAPFFLWISDLSLPDPTNLFTLFGLIDWNCPDFLSIG
ILPIILGLTMVIQQKLSPSHYDDGTQAFMIKAMPYVFMILFASFPSGLVLYWVFNNVLSLLQQFVIGKYLFTKKFKAMTK
TQESLP

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790140, Length=430, Percent_Identity=30.4651162790698, Blast_Score=193, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 64755; Mature: 64755

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQTYNVFIATLLSFLVIIGWNLVFYNPTQRESFHEVQKKESVKVYESLESTLSTERIKI
CCCHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
SSSKLEGSIQLTGLALDDLILKDYKSDDLKDQYRLLYPNKTKGAYFINPGWTIPGDPGLR
ECCCCCCEEEEEEEEHHHHHHHCCCCCCCCCCEEEECCCCCCCEEEECCCCCCCCCCCCC
TPSSKTKWQADSELLTPGSPVTFSWDNGFGLLFKVVVSIDDNYMFTFKQIVENKSQNDLS
CCCCCCCCCCCCCEECCCCCEEEEECCCHHEEHHEEEEECCCEEHHHHHHHCCCCCCCCC
VGSHFTITKSLPETNKSMLIMHEGPVGVVKDQLMELKYSKIAKKNKSIAFDEDTQNQRGW
CCCEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCC
FGFSDKYWFVSQIFENSSDGKVYISHIDDKSDDIFRITNFNAQKIVRGGGLIVKETMLFA
CCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCHHHHHCCCCEEEEHHHHHC
GPKKLSLLEEYAQNMRIYLFDRAVDFGVLYFITKPISKLLQVFHHLVGNFGVAIILLTFF
CCHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRVLMLPLSIKSGISMFKIKELQPEILKIKSMYQNDKDALNRASVELFRKHRVTPMSGCL
HHHHHHHHHHHCCCCEEEEHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHH
PTLLQVPVFFALYKVIFITVEMRQAPFFLWISDLSLPDPTNLFTLFGLIDWNCPDFLSIG
HHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCCCHHHHEEHEECCCCCHHHHHH
ILPIILGLTMVIQQKLSPSHYDDGTQAFMIKAMPYVFMILFASFPSGLVLYWVFNNVLSL
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LQQFVIGKYLFTKKFKAMTKTQESLP
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQQTYNVFIATLLSFLVIIGWNLVFYNPTQRESFHEVQKKESVKVYESLESTLSTERIKI
CCCHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
SSSKLEGSIQLTGLALDDLILKDYKSDDLKDQYRLLYPNKTKGAYFINPGWTIPGDPGLR
ECCCCCCEEEEEEEEHHHHHHHCCCCCCCCCCEEEECCCCCCCEEEECCCCCCCCCCCCC
TPSSKTKWQADSELLTPGSPVTFSWDNGFGLLFKVVVSIDDNYMFTFKQIVENKSQNDLS
CCCCCCCCCCCCCEECCCCCEEEEECCCHHEEHHEEEEECCCEEHHHHHHHCCCCCCCCC
VGSHFTITKSLPETNKSMLIMHEGPVGVVKDQLMELKYSKIAKKNKSIAFDEDTQNQRGW
CCCEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCC
FGFSDKYWFVSQIFENSSDGKVYISHIDDKSDDIFRITNFNAQKIVRGGGLIVKETMLFA
CCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCHHHHHCCCCEEEEHHHHHC
GPKKLSLLEEYAQNMRIYLFDRAVDFGVLYFITKPISKLLQVFHHLVGNFGVAIILLTFF
CCHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRVLMLPLSIKSGISMFKIKELQPEILKIKSMYQNDKDALNRASVELFRKHRVTPMSGCL
HHHHHHHHHHHCCCCEEEEHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHH
PTLLQVPVFFALYKVIFITVEMRQAPFFLWISDLSLPDPTNLFTLFGLIDWNCPDFLSIG
HHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCCCHHHHEEHEECCCCCHHHHHH
ILPIILGLTMVIQQKLSPSHYDDGTQAFMIKAMPYVFMILFASFPSGLVLYWVFNNVLSL
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LQQFVIGKYLFTKKFKAMTKTQESLP
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA