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The map label for this gene is ftsZ

Identifier: 88608360

GI number: 88608360

Start: 280727

End: 281845

Strand: Direct

Name: ftsZ

Synonym: NSE_0342

Alternate gene names: 88608360

Gene position: 280727-281845 (Clockwise)

Preceding gene: 88608622

Following gene: 88608249

Centisome position: 32.68

GC content: 44.24

Gene sequence:

>1119_bases
ATGACCTTGCGTTTATCTGTACCGTTGGAACAGAATCAGCGTCAGAGTTTGCTTTGTCCGAAAATAGCGGTTATCGGAGT
CGGCGGGGCAGGTGGTAACGCGATCAATAATATGATTAACTCCGGTCTCCGTGGTGTTAAATTTATTGCTGCGAATACTG
ATGCACAAGCTCTTGAGCATTCTCTTGCTGATGTGAAAATTCAATTGGGGGCTAATCTCACAAAGGGGTTGGGAGCTGGA
TCCATACCTGAGATCGGCAGGCAGGCAGCAGAAGAATCTATTAATGAGCTTGCTGAGGCTATAGAAGACACTGATATGCT
ATTTATCACTGCCGGTATGGGTGGCGGTACCGGTACTGGTGCAGCAACGGTGATAGCAAGATTGGCAATGGAGCGAAAAG
TTCTAGTCGTGGCAGTTGTGACGAAACCTTTTTATTTTGAGGGCGCTCGCAGGGCTAAGGTAGCTGAGGTTGGGCTTGAA
GCGTTAAGAAGGGTAGTGGATACCTATATAGTGATTAATAATCAAAATCTTTTCAGGATAGCGAATGAAAAAACAACATT
TGCGGATGCGTTTAAAGAGGTTGATAAAATTCTCTATTTTCATGTGAGAGAGATAAGTAGCTTGATGGTGAATCCAGGGT
ATATTAACCTTGATTTTGCAGATGTCCGTTCAGTCATGAGCAAGATGGGCAAAGCTCTTATGGGGACAAGCGAAGCTTCG
GGCGAGAATAGGGCAGTTAAAGCCGCTGAGAATTCTATAGCGAATCCGTTGCTGGATAATCTTTCTGTGCAAGATGCAAA
AGGTATTTTGATTAATATTACTGGCGGTCCGGATATGACGCTTTTTGAAGTAGATGCAGCCGCAAATTGTGTCAGAGAGA
AGGCTAGTGAGAATGTTAATATAATTTTTGGTTCTACTTGTTCCGAGTCCATGAGTAATGTCGTGCGGGTCTCTGTTGTT
GCCACTGGAATTTCTCCAGATCACAGTGAATTGAGCGAGACAGGGGATCTAGATGAGGAAGGTTTTTCTGGGTGGAGAGA
GGAGAAATCTGACGAGCAAAAAAAAATGGAGTTGCTCGAGATTCCGGCTTTTATCCGCAGGGTAAAGAAGAAATCTTGA

Upstream 100 bases:

>100_bases
TTCTCAAGAGAGGGTTAGGCAGATACATGCTCGGGCAATGAAGAAAGTGACAGAGTATGTGGAAAAGCATGGAAGAAAAC
TTGGGATAGTATAACCGAAC

Downstream 100 bases:

>100_bases
TTTTTCTAGTAGACCCTAATCGTGTTTTGTAGGTTTCGTTTTTACAGTCTTATCGAATATCGCTTTCTCGGTTTACCGTG
CTTATTTGTTTCGTTTTTTC

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MTLRLSVPLEQNQRQSLLCPKIAVIGVGGAGGNAINNMINSGLRGVKFIAANTDAQALEHSLADVKIQLGANLTKGLGAG
SIPEIGRQAAEESINELAEAIEDTDMLFITAGMGGGTGTGAATVIARLAMERKVLVVAVVTKPFYFEGARRAKVAEVGLE
ALRRVVDTYIVINNQNLFRIANEKTTFADAFKEVDKILYFHVREISSLMVNPGYINLDFADVRSVMSKMGKALMGTSEAS
GENRAVKAAENSIANPLLDNLSVQDAKGILINITGGPDMTLFEVDAAANCVREKASENVNIIFGSTCSESMSNVVRVSVV
ATGISPDHSELSETGDLDEEGFSGWREEKSDEQKKMELLEIPAFIRRVKKKS

Sequences:

>Translated_372_residues
MTLRLSVPLEQNQRQSLLCPKIAVIGVGGAGGNAINNMINSGLRGVKFIAANTDAQALEHSLADVKIQLGANLTKGLGAG
SIPEIGRQAAEESINELAEAIEDTDMLFITAGMGGGTGTGAATVIARLAMERKVLVVAVVTKPFYFEGARRAKVAEVGLE
ALRRVVDTYIVINNQNLFRIANEKTTFADAFKEVDKILYFHVREISSLMVNPGYINLDFADVRSVMSKMGKALMGTSEAS
GENRAVKAAENSIANPLLDNLSVQDAKGILINITGGPDMTLFEVDAAANCVREKASENVNIIFGSTCSESMSNVVRVSVV
ATGISPDHSELSETGDLDEEGFSGWREEKSDEQKKMELLEIPAFIRRVKKKS
>Mature_371_residues
TLRLSVPLEQNQRQSLLCPKIAVIGVGGAGGNAINNMINSGLRGVKFIAANTDAQALEHSLADVKIQLGANLTKGLGAGS
IPEIGRQAAEESINELAEAIEDTDMLFITAGMGGGTGTGAATVIARLAMERKVLVVAVVTKPFYFEGARRAKVAEVGLEA
LRRVVDTYIVINNQNLFRIANEKTTFADAFKEVDKILYFHVREISSLMVNPGYINLDFADVRSVMSKMGKALMGTSEASG
ENRAVKAAENSIANPLLDNLSVQDAKGILINITGGPDMTLFEVDAAANCVREKASENVNIIFGSTCSESMSNVVRVSVVA
TGISPDHSELSETGDLDEEGFSGWREEKSDEQKKMELLEIPAFIRRVKKKS

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=357, Percent_Identity=41.7366946778711, Blast_Score=245, Evalue=4e-66,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 39895; Mature: 39764

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS01134 FTSZ_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRLSVPLEQNQRQSLLCPKIAVIGVGGAGGNAINNMINSGLRGVKFIAANTDAQALEH
CEEEEECCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHH
SLADVKIQLGANLTKGLGAGSIPEIGRQAAEESINELAEAIEDTDMLFITAGMGGGTGTG
HHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCH
AATVIARLAMERKVLVVAVVTKPFYFEGARRAKVAEVGLEALRRVVDTYIVINNQNLFRI
HHHHHHHHHHCCCEEEEEEECCCCEECCCCHHHHHHHHHHHHHHHHHEEEEECCCCEEEE
ANEKTTFADAFKEVDKILYFHVREISSLMVNPGYINLDFADVRSVMSKMGKALMGTSEAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCC
GENRAVKAAENSIANPLLDNLSVQDAKGILINITGGPDMTLFEVDAAANCVREKASENVN
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEHHHHHHHHHHHCCCEE
IIFGSTCSESMSNVVRVSVVATGISPDHSELSETGDLDEEGFSGWREEKSDEQKKMELLE
EEECCCHHHHHHHHEEEEEEEECCCCCHHHHHHCCCCCHHHCCCHHHHCCHHHHHHHHHH
IPAFIRRVKKKS
HHHHHHHHHCCC
>Mature Secondary Structure 
TLRLSVPLEQNQRQSLLCPKIAVIGVGGAGGNAINNMINSGLRGVKFIAANTDAQALEH
EEEEECCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHH
SLADVKIQLGANLTKGLGAGSIPEIGRQAAEESINELAEAIEDTDMLFITAGMGGGTGTG
HHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCH
AATVIARLAMERKVLVVAVVTKPFYFEGARRAKVAEVGLEALRRVVDTYIVINNQNLFRI
HHHHHHHHHHCCCEEEEEEECCCCEECCCCHHHHHHHHHHHHHHHHHEEEEECCCCEEEE
ANEKTTFADAFKEVDKILYFHVREISSLMVNPGYINLDFADVRSVMSKMGKALMGTSEAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCC
GENRAVKAAENSIANPLLDNLSVQDAKGILINITGGPDMTLFEVDAAANCVREKASENVN
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEHHHHHHHHHHHCCCEE
IIFGSTCSESMSNVVRVSVVATGISPDHSELSETGDLDEEGFSGWREEKSDEQKKMELLE
EEECCCHHHHHHHHEEEEEEEECCCCCHHHHHHCCCCCHHHCCCHHHHCCHHHHHHHHHH
IPAFIRRVKKKS
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]