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The map label for this gene is 88607873

Identifier: 88607873

GI number: 88607873

Start: 1099468

End: 1101099

Strand: Direct

Name: 88607873

Synonym: APH_1036

Alternate gene names: NA

Gene position: 1099468-1101099 (Clockwise)

Preceding gene: 88607606

Following gene: 88607556

Centisome position: 74.73

GC content: 44.06

Gene sequence:

>1632_bases
ATGTATGTAGACGATAATAAGTTTTTGTTCCTGCCTCTGGGTGGTGTAGGAAAGATTGGTATGAATGTTTCGCTTTACCA
TGTTCATGGTAAGTGGATAATGATAGATCTAGGTGCTGGGTTTGCCGACCCTGATAGCATGCCGGGTGTGGATCTAGTTG
TTGCTGATATTAGCTTCATAAGAGAAAGGCGTAAGGATCTCGTAGGTGTAGTTTTGACTCATGCACATGAAGATCACATA
GGCGCTATCCCTTACCTATGGGAAGATCTAAGATGTCCTATATATGCTACAAAGTTCACTGCATCTTTTGTAAGATCAAA
GGTAGAGCAGTTTTCCTTAAATATACCGATAGTGGAGGTTGATCCCGGTGTGCCTTTGGAACTTGGGCCCTTCACGTTGG
AGTTCGTGAGTATGACGCACTCTATACCGGAGATGCACTCTATTGCGGTACGTACAGACTTGGGAAGTGTTCTACATACA
GGAGATTGGAAGCTAGATACCAATCCTGTGATTGGTTCGGTATCAGATTTAGAAAAGCTGAAGCGCCTGGGTGATGATGG
TATTTTGGCAGTTGTTTCTGATTCCACTAACATATTTACTGAAGGCACTTCAGGGTCTGAAGGCAGCCTGCATGATAGCA
TACTTGATATCGTTAAACGTTGTAAAAATAGGGTTGCTATTTCGTTATTTGCTTCCAACGTAGCTAGAATATCTACTCTC
AGTAGGATAGCTAAGGAGACGGGAAGAAAGGTGGTGGTACTTGGTAGATCTTTGTCACGAGCTTTGGGGGCTGCACACGA
ATGTGGCTATCTTGATGATCCGGAAAACTTTCTTGATGGACGTGAGAATATAAACCTACCAAAGGAGAAGGTTCTCTATC
TTTGTACAGGGTGTCAGGGCGAGCCTATGGCTGCTACTGCACGTTTAGCTAGTGGTTCGCATCCATTTGCTACGCTCGAA
AGTGGTGATACTGTCATTTTTTCCTCTAAGATTATTCCTGGAAATGAAAGACGTATCTTCCGGGTTTTCAACAAGCTAGT
TCAGCAGGGTGTGGAGGTTGTTACTGAATTCACTGAATCAGTACACGTATCGGGGCACCCTTCAAGGACTGATGTGCGTA
CTCTGTATTCTCTGCTGAAGCCTAAGTTGTGTCTGCCTGTACACGGTGAGTACATACACATGTATGAGCATGCACGTTTG
GCTGAAGAATGTGGCATAGAACGTTGTATTGTCTCTTCTCCTGGAAACGTGATAGATTTGGTAGAGAGAAAGGTAGTAGA
TACTGTAGACTGTGGAGTTTACGGTGTTGATGGAGAGTTCTTGAGATCTGCTGACGATAGTGTCATAAGCGCCCGTAGAA
AGATGCGTGATGCTGGTGCTGTGATTGTGACGCTGTTAATGAATAGGGATCATCAACTGATCAGGGAGCCTCTTGTGATT
GCGCCGGGAGCTCTAGATAGTACGGAAGATCATGTGCTACTGAGTGAAGTGGCTCGGAAAATTAGCGCGGGGGTTGCAGG
TCGTAGACCTAAAAACATAAAGGGTTATATAAGAAATTTGGTTTTTGCTTTTCTTAAAGACGTGGTAAAGGGCAAACCAT
TGGTGGAAGTACAGTTGGAATATGTCAATTAG

Upstream 100 bases:

>100_bases
AGTCAAAAATGGCTTTGCGGGGCCTATATTCATGTTTTTTCTTTAAAAACGTAAGCATCTATGCTACTTATGATGCGTTT
TGTGGCGCTTGTATTTTGTA

Downstream 100 bases:

>100_bases
GCTTGGAGTTGCTACGTTTTTCATATTTTTATTATTCTGTTGTGGGGGTGCTGTTGCCTCTTTGCGTCTAAGTATCACTA
AGGGCAACACTGGGAAACTA

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: RNase J1 [H]

Number of amino acids: Translated: 543; Mature: 543

Protein sequence:

>543_residues
MYVDDNKFLFLPLGGVGKIGMNVSLYHVHGKWIMIDLGAGFADPDSMPGVDLVVADISFIRERRKDLVGVVLTHAHEDHI
GAIPYLWEDLRCPIYATKFTASFVRSKVEQFSLNIPIVEVDPGVPLELGPFTLEFVSMTHSIPEMHSIAVRTDLGSVLHT
GDWKLDTNPVIGSVSDLEKLKRLGDDGILAVVSDSTNIFTEGTSGSEGSLHDSILDIVKRCKNRVAISLFASNVARISTL
SRIAKETGRKVVVLGRSLSRALGAAHECGYLDDPENFLDGRENINLPKEKVLYLCTGCQGEPMAATARLASGSHPFATLE
SGDTVIFSSKIIPGNERRIFRVFNKLVQQGVEVVTEFTESVHVSGHPSRTDVRTLYSLLKPKLCLPVHGEYIHMYEHARL
AEECGIERCIVSSPGNVIDLVERKVVDTVDCGVYGVDGEFLRSADDSVISARRKMRDAGAVIVTLLMNRDHQLIREPLVI
APGALDSTEDHVLLSEVARKISAGVAGRRPKNIKGYIRNLVFAFLKDVVKGKPLVEVQLEYVN

Sequences:

>Translated_543_residues
MYVDDNKFLFLPLGGVGKIGMNVSLYHVHGKWIMIDLGAGFADPDSMPGVDLVVADISFIRERRKDLVGVVLTHAHEDHI
GAIPYLWEDLRCPIYATKFTASFVRSKVEQFSLNIPIVEVDPGVPLELGPFTLEFVSMTHSIPEMHSIAVRTDLGSVLHT
GDWKLDTNPVIGSVSDLEKLKRLGDDGILAVVSDSTNIFTEGTSGSEGSLHDSILDIVKRCKNRVAISLFASNVARISTL
SRIAKETGRKVVVLGRSLSRALGAAHECGYLDDPENFLDGRENINLPKEKVLYLCTGCQGEPMAATARLASGSHPFATLE
SGDTVIFSSKIIPGNERRIFRVFNKLVQQGVEVVTEFTESVHVSGHPSRTDVRTLYSLLKPKLCLPVHGEYIHMYEHARL
AEECGIERCIVSSPGNVIDLVERKVVDTVDCGVYGVDGEFLRSADDSVISARRKMRDAGAVIVTLLMNRDHQLIREPLVI
APGALDSTEDHVLLSEVARKISAGVAGRRPKNIKGYIRNLVFAFLKDVVKGKPLVEVQLEYVN
>Mature_543_residues
MYVDDNKFLFLPLGGVGKIGMNVSLYHVHGKWIMIDLGAGFADPDSMPGVDLVVADISFIRERRKDLVGVVLTHAHEDHI
GAIPYLWEDLRCPIYATKFTASFVRSKVEQFSLNIPIVEVDPGVPLELGPFTLEFVSMTHSIPEMHSIAVRTDLGSVLHT
GDWKLDTNPVIGSVSDLEKLKRLGDDGILAVVSDSTNIFTEGTSGSEGSLHDSILDIVKRCKNRVAISLFASNVARISTL
SRIAKETGRKVVVLGRSLSRALGAAHECGYLDDPENFLDGRENINLPKEKVLYLCTGCQGEPMAATARLASGSHPFATLE
SGDTVIFSSKIIPGNERRIFRVFNKLVQQGVEVVTEFTESVHVSGHPSRTDVRTLYSLLKPKLCLPVHGEYIHMYEHARL
AEECGIERCIVSSPGNVIDLVERKVVDTVDCGVYGVDGEFLRSADDSVISARRKMRDAGAVIVTLLMNRDHQLIREPLVI
APGALDSTEDHVLLSEVARKISAGVAGRRPKNIKGYIRNLVFAFLKDVVKGKPLVEVQLEYVN

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR004613
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 59629; Mature: 59629

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVDDNKFLFLPLGGVGKIGMNVSLYHVHGKWIMIDLGAGFADPDSMPGVDLVVADISFI
CEECCCCEEEEECCCCCCCCCEEEEEEEECEEEEEECCCCCCCCCCCCCCEEEHHHHHHH
RERRKDLVGVVLTHAHEDHIGAIPYLWEDLRCPIYATKFTASFVRSKVEQFSLNIPIVEV
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCEEEEE
DPGVPLELGPFTLEFVSMTHSIPEMHSIAVRTDLGSVLHTGDWKLDTNPVIGSVSDLEKL
CCCCCEEECCHHHHHHHHHHCCCHHHHEEEEHHHHHHHCCCCCEECCCCCCCCHHHHHHH
KRLGDDGILAVVSDSTNIFTEGTSGSEGSLHDSILDIVKRCKNRVAISLFASNVARISTL
HHCCCCCEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHH
SRIAKETGRKVVVLGRSLSRALGAAHECGYLDDPENFLDGRENINLPKEKVLYLCTGCQG
HHHHHHHCCEEEEECCHHHHHHCCHHCCCCCCCCHHHHCCCCCCCCCHHHEEEEEECCCC
EPMAATARLASGSHPFATLESGDTVIFSSKIIPGNERRIFRVFNKLVQQGVEVVTEFTES
CCCHHHHHHCCCCCCEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VHVSGHPSRTDVRTLYSLLKPKLCLPVHGEYIHMYEHARLAEECGIERCIVSSPGNVIDL
EECCCCCCCHHHHHHHHHHCCCEEEECCCCEEEHHHHHHHHHHCCCCEEEECCCCCHHHH
VERKVVDTVDCGVYGVDGEFLRSADDSVISARRKMRDAGAVIVTLLMNRDHQLIREPLVI
HHHHHHHHHCCCEECCCHHHHHCCCHHHHHHHHHHHHCCCEEHHHHHCCCHHHHHCCCEE
APGALDSTEDHVLLSEVARKISAGVAGRRPKNIKGYIRNLVFAFLKDVVKGKPLVEVQLE
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEE
YVN
ECC
>Mature Secondary Structure
MYVDDNKFLFLPLGGVGKIGMNVSLYHVHGKWIMIDLGAGFADPDSMPGVDLVVADISFI
CEECCCCEEEEECCCCCCCCCEEEEEEEECEEEEEECCCCCCCCCCCCCCEEEHHHHHHH
RERRKDLVGVVLTHAHEDHIGAIPYLWEDLRCPIYATKFTASFVRSKVEQFSLNIPIVEV
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCEEEEE
DPGVPLELGPFTLEFVSMTHSIPEMHSIAVRTDLGSVLHTGDWKLDTNPVIGSVSDLEKL
CCCCCEEECCHHHHHHHHHHCCCHHHHEEEEHHHHHHHCCCCCEECCCCCCCCHHHHHHH
KRLGDDGILAVVSDSTNIFTEGTSGSEGSLHDSILDIVKRCKNRVAISLFASNVARISTL
HHCCCCCEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHH
SRIAKETGRKVVVLGRSLSRALGAAHECGYLDDPENFLDGRENINLPKEKVLYLCTGCQG
HHHHHHHCCEEEEECCHHHHHHCCHHCCCCCCCCHHHHCCCCCCCCCHHHEEEEEECCCC
EPMAATARLASGSHPFATLESGDTVIFSSKIIPGNERRIFRVFNKLVQQGVEVVTEFTES
CCCHHHHHHCCCCCCEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VHVSGHPSRTDVRTLYSLLKPKLCLPVHGEYIHMYEHARLAEECGIERCIVSSPGNVIDL
EECCCCCCCHHHHHHHHHHCCCEEEECCCCEEEHHHHHHHHHHCCCCEEEECCCCCHHHH
VERKVVDTVDCGVYGVDGEFLRSADDSVISARRKMRDAGAVIVTLLMNRDHQLIREPLVI
HHHHHHHHHCCCEECCCHHHHHCCCHHHHHHHHHHHHCCCEEHHHHHCCCHHHHHCCCEE
APGALDSTEDHVLLSEVARKISAGVAGRRPKNIKGYIRNLVFAFLKDVVKGKPLVEVQLE
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEE
YVN
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA