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The map label for this gene is rnhB

Identifier: 88607606

GI number: 88607606

Start: 1081522

End: 1082154

Strand: Direct

Name: rnhB

Synonym: APH_1022

Alternate gene names: 88607606

Gene position: 1081522-1082154 (Clockwise)

Preceding gene: 88607254

Following gene: 88607873

Centisome position: 73.51

GC content: 43.6

Gene sequence:

>633_bases
ATGCCTAACTTCTCTTATGAAGATTCATTTAGTCATGGCTCCAACGCTATTGTTGTTGGCGTTGATGAAGTTGGCTATGG
CTCAATAGCCGGCCCAGTGGTCGCTGCTGCTGTGTATATACCAGACCGCAATGTCGAGTGTATCCCAAATATAAAAGACT
CTAAACTGCTGACCCCGAAAAAACGTGATGCTCTTTATAAAGAACTTCTATCCCACACCGTATGCGGCACTGGCCTAGCA
AGCATTGATGAGATAGAAGAGCACAACATACTTGTAGCCTCACACATGGCAATGAGAAGAGCATTAGAAAACCTTAATCT
ACAACGCATAGACCTTGTTTTAGTCGACGGCTCAAGGGAATTGAAGTCCCAATGGCCAAGCAAATCCATAATAAATGGGG
ATGAACTCAGCATATCAATCGCAGCTGCTTCCATAGTAGCAAAAGTTACACGAGATAACATGATGCGTGAATTACACGAC
CAATACCCTGAATACCACTGGAACAAGAACTGCGGTTATGGTACAGCAGCCCATATCCTCGCTCTCAAACAGCACGGAGC
TACACCCCTACATCGCAAAACATTTGCCCCTGTAAAAAAGTGTATAATCTCAACAAAAAACCAAGACAAATAA

Upstream 100 bases:

>100_bases
CCATGTGCATGCATATTTGGGGGGTCACTAAAGTAACATCTCACTTGACTTAAGCATCAGTAAACACAATGATCTCTGAT
TATCGTACAATCTTTGCCCT

Downstream 100 bases:

>100_bases
CTCTATTCTCTCTACGCCCCTAAAATATCACCTACACAACACAGCACTTATTATGCTATCAGAATGAAATGATGCCCTGC
TCTCTCTATACCAACCAAAA

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MPNFSYEDSFSHGSNAIVVGVDEVGYGSIAGPVVAAAVYIPDRNVECIPNIKDSKLLTPKKRDALYKELLSHTVCGTGLA
SIDEIEEHNILVASHMAMRRALENLNLQRIDLVLVDGSRELKSQWPSKSIINGDELSISIAAASIVAKVTRDNMMRELHD
QYPEYHWNKNCGYGTAAHILALKQHGATPLHRKTFAPVKKCIISTKNQDK

Sequences:

>Translated_210_residues
MPNFSYEDSFSHGSNAIVVGVDEVGYGSIAGPVVAAAVYIPDRNVECIPNIKDSKLLTPKKRDALYKELLSHTVCGTGLA
SIDEIEEHNILVASHMAMRRALENLNLQRIDLVLVDGSRELKSQWPSKSIINGDELSISIAAASIVAKVTRDNMMRELHD
QYPEYHWNKNCGYGTAAHILALKQHGATPLHRKTFAPVKKCIISTKNQDK
>Mature_209_residues
PNFSYEDSFSHGSNAIVVGVDEVGYGSIAGPVVAAAVYIPDRNVECIPNIKDSKLLTPKKRDALYKELLSHTVCGTGLAS
IDEIEEHNILVASHMAMRRALENLNLQRIDLVLVDGSRELKSQWPSKSIINGDELSISIAAASIVAKVTRDNMMRELHDQ
YPEYHWNKNCGYGTAAHILALKQHGATPLHRKTFAPVKKCIISTKNQDK

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=195, Percent_Identity=42.0512820512821, Blast_Score=134, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_ANAPZ (Q2GJ70)

Other databases:

- EMBL:   CP000235
- RefSeq:   YP_505581.1
- ProteinModelPortal:   Q2GJ70
- SMR:   Q2GJ70
- STRING:   Q2GJ70
- GeneID:   3930611
- GenomeReviews:   CP000235_GR
- KEGG:   aph:APH_1022
- NMPDR:   fig|212042.5.peg.968
- TIGR:   APH_1022
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- PhylomeDB:   Q2GJ70
- ProtClustDB:   PRK00015
- BioCyc:   APHA212042:APH_1022-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 23192; Mature: 23061

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNFSYEDSFSHGSNAIVVGVDEVGYGSIAGPVVAAAVYIPDRNVECIPNIKDSKLLTPK
CCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHEEEEEECCCCCEECCCCCCCCCCCCH
KRDALYKELLSHTVCGTGLASIDEIEEHNILVASHMAMRRALENLNLQRIDLVLVDGSRE
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEHHHHHHHHHHHHHCCEEEEEEEEECCCHH
LKSQWPSKSIINGDELSISIAAASIVAKVTRDNMMRELHDQYPEYHWNKNCGYGTAAHIL
HHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
ALKQHGATPLHRKTFAPVKKCIISTKNQDK
HHHHCCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PNFSYEDSFSHGSNAIVVGVDEVGYGSIAGPVVAAAVYIPDRNVECIPNIKDSKLLTPK
CCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHEEEEEECCCCCEECCCCCCCCCCCCH
KRDALYKELLSHTVCGTGLASIDEIEEHNILVASHMAMRRALENLNLQRIDLVLVDGSRE
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEHHHHHHHHHHHHHCCEEEEEEEEECCCHH
LKSQWPSKSIINGDELSISIAAASIVAKVTRDNMMRELHDQYPEYHWNKNCGYGTAAHIL
HHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
ALKQHGATPLHRKTFAPVKKCIISTKNQDK
HHHHCCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA