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The map label for this gene is ctrA [H]

Identifier: 88607685

GI number: 88607685

Start: 1160135

End: 1160965

Strand: Reverse

Name: ctrA [H]

Synonym: APH_1099

Alternate gene names: 88607685

Gene position: 1160965-1160135 (Counterclockwise)

Preceding gene: 88606714

Following gene: 88607131

Centisome position: 78.91

GC content: 42.6

Gene sequence:

>831_bases
ATGCGCATACTGTTAATAGAAGATGATGTTGCCTGTGCTAAAGCAGTTGAGGCTTCTTTGTCTGCAGAGGGGCATTTTTG
TGAGACTATGGCTTCCGCTCAGGATTGCTATGGTAGTATAATTCCCAAGAACGATGATTATGACGTTGTTATACTGGATA
TACACTTTCCTGGAAAGATTGATGGATATGATATATTAGTGAAGCTTCGGGAATCAGGCATCAGAGTACCTGTACTAATA
TTGTCATGTATTTCGTCGGTAGCTCATAAGGTTAAGGGACTTTATTATGGTGCTGATGATTACATTACTAAGCCTTTTCA
TAAGAGTGAGTTACTTGCAAGAATCAAGGCTGTTGTAAGACGTACTCGTGGACATCCTGAATCGATAGTGCGTGTCGGAA
ATATATCAATAAACTTGGATCACAAGTGTGTTTCATGCAACGGGAACATCATACACTTAACTAAGAAAGAATACGGTATG
ATAGAGCTTTTGTCGTCTAGGTTGGGCACTGTACTCACGAAGGAGATGTTTTTATCTCATTTATATAGGGAGTTGGATGA
GCCATCTGATGATAAGATCATAGATGTGTTCATGTGTAAGCTGCGCAAGAAGCTTAAGGTCGCCAATAACGGGAAAAATT
ACATTGAGACGGTATGGGGCAGGGGCTATGTGCTGAAGGAGCATCCTTGTGATGATGGAGAGGATGATGCTTCTGGGGCC
ACTGACAAGAGGTGTGCTGTAGCCGGTTCTACTGAGGAAGATAGTGCGAGCAAGGCTTCTGGGTATGAATGGTCTGCAGA
GCAAAATCGGGATTATGCGGAAGAAGCCTAG

Upstream 100 bases:

>100_bases
TAATGATGGTATGCATGTTAGTTTCTAGCGAGGGTGTAGTGGAAGGAACGTTTGTGAGTCGTTGTGTGCCAGGGTTTTGT
TTGGTTTTTGAGGTGTAGGT

Downstream 100 bases:

>100_bases
TTTTGTGGATTGTTTTTTTCAGGGTGTGTGATAGAGTTGAGCCCTGTAGGTAGGAACGGGGTTTTGCATGGCTGTATTCG
TGCATCGCAATGATTTGCCA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MRILLIEDDVACAKAVEASLSAEGHFCETMASAQDCYGSIIPKNDDYDVVILDIHFPGKIDGYDILVKLRESGIRVPVLI
LSCISSVAHKVKGLYYGADDYITKPFHKSELLARIKAVVRRTRGHPESIVRVGNISINLDHKCVSCNGNIIHLTKKEYGM
IELLSSRLGTVLTKEMFLSHLYRELDEPSDDKIIDVFMCKLRKKLKVANNGKNYIETVWGRGYVLKEHPCDDGEDDASGA
TDKRCAVAGSTEEDSASKASGYEWSAEQNRDYAEEA

Sequences:

>Translated_276_residues
MRILLIEDDVACAKAVEASLSAEGHFCETMASAQDCYGSIIPKNDDYDVVILDIHFPGKIDGYDILVKLRESGIRVPVLI
LSCISSVAHKVKGLYYGADDYITKPFHKSELLARIKAVVRRTRGHPESIVRVGNISINLDHKCVSCNGNIIHLTKKEYGM
IELLSSRLGTVLTKEMFLSHLYRELDEPSDDKIIDVFMCKLRKKLKVANNGKNYIETVWGRGYVLKEHPCDDGEDDASGA
TDKRCAVAGSTEEDSASKASGYEWSAEQNRDYAEEA
>Mature_276_residues
MRILLIEDDVACAKAVEASLSAEGHFCETMASAQDCYGSIIPKNDDYDVVILDIHFPGKIDGYDILVKLRESGIRVPVLI
LSCISSVAHKVKGLYYGADDYITKPFHKSELLARIKAVVRRTRGHPESIVRVGNISINLDHKCVSCNGNIIHLTKKEYGM
IELLSSRLGTVLTKEMFLSHLYRELDEPSDDKIIDVFMCKLRKKLKVANNGKNYIETVWGRGYVLKEHPCDDGEDDASGA
TDKRCAVAGSTEEDSASKASGYEWSAEQNRDYAEEA

Specific function: Essential protein that plays a role in the control of cell division, possibly through the transcriptional regulation of ccrM, rpoD, pleC, minC and ftsZ genes [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=231, Percent_Identity=37.6623376623377, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=34.2222222222222, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=33.0396475770925, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=31.4410480349345, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=34.9775784753363, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=29.4372294372294, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=31.1965811965812, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=26.9911504424779, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=27.8969957081545, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=30.0884955752212, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=27.3542600896861, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=27.2340425531915, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1790863, Length=244, Percent_Identity=27.8688524590164, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI145693140, Length=241, Percent_Identity=26.5560165975104, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 30708; Mature: 30708

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLIEDDVACAKAVEASLSAEGHFCETMASAQDCYGSIIPKNDDYDVVILDIHFPGKI
CEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCC
DGYDILVKLRESGIRVPVLILSCISSVAHKVKGLYYGADDYITKPFHKSELLARIKAVVR
CCHHEEEEEHHCCCCHHHHHHHHHHHHHHHHHCEEECCCCCCCCCCCHHHHHHHHHHHHH
RTRGHPESIVRVGNISINLDHKCVSCNGNIIHLTKKEYGMIELLSSRLGTVLTKEMFLSH
HHCCCHHHEEEEEEEEEEECCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
LYRELDEPSDDKIIDVFMCKLRKKLKVANNGKNYIETVWGRGYVLKEHPCDDGEDDASGA
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCC
TDKRCAVAGSTEEDSASKASGYEWSAEQNRDYAEEA
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRILLIEDDVACAKAVEASLSAEGHFCETMASAQDCYGSIIPKNDDYDVVILDIHFPGKI
CEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCC
DGYDILVKLRESGIRVPVLILSCISSVAHKVKGLYYGADDYITKPFHKSELLARIKAVVR
CCHHEEEEEHHCCCCHHHHHHHHHHHHHHHHHCEEECCCCCCCCCCCHHHHHHHHHHHHH
RTRGHPESIVRVGNISINLDHKCVSCNGNIIHLTKKEYGMIELLSSRLGTVLTKEMFLSH
HHCCCHHHEEEEEEEEEEECCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
LYRELDEPSDDKIIDVFMCKLRKKLKVANNGKNYIETVWGRGYVLKEHPCDDGEDDASGA
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCC
TDKRCAVAGSTEEDSASKASGYEWSAEQNRDYAEEA
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA