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The map label for this gene is virB9-2 [H]

Identifier: 88607325

GI number: 88607325

Start: 1464845

End: 1465690

Strand: Reverse

Name: virB9-2 [H]

Synonym: APH_1405

Alternate gene names: 88607325

Gene position: 1465690-1464845 (Counterclockwise)

Preceding gene: 88607942

Following gene: 88607929

Centisome position: 99.62

GC content: 40.43

Gene sequence:

>846_bases
ATGATGAATTTCTATAAAAATTTTTATGTTGCTTTGGTAACGGCTTTCGCGCTGTTCTCTATGAGTAAAGCATGCTTTGC
CAGCACAAATATTGGCGTACCAGTTTCTGTAGATAGTAGAATAAAGACATTTGTCTACAGTCAGAATGAGGTTTTTCCGG
TTGTGTTCAACTATGGCTATCATTCCTACATAGAATTCTCGCAAGGTGAGACGGTGCGAGTTATGGCTTTAGGAGATAAT
GCAAATTGGAAGATAAGGCCGGTGGACAACAAGTTATACGTCATGCCCTTGGAAAAAGAGGGGCACACTAATATGCTCAT
AGAAACGAGTAAGGGGCGGAGTTACGCTTTTGATTTGATATCGACTGCGATTCCTCTGAGTGGAGGTGCTGCATCTAGTA
TTAACAAGTTGGGAAAGACTAATTCTGCATTAGCAGACTTAGCTTATGTAGTGCGTTTTTACTATCCGCAGAGTGATAGA
AATTTTGATATCATGGGACAGAAACTTGAGATATCTCCTCCTAGCCTGGCTAGCAGTTTAGATGCTGATGATGTGGAAAT
AGAGCCAAATGCCACTAGAACCAACTATATGTTTACTGGTGGAAGTGCTCACGTTTCTCTAGCTCCTACGCAGGCTTTTG
ATGATGGATATCTGACATACTTTCAGTTTGGTAAAAATAACAAAGAAATTCCCAAAATCTACGTTGTGAAGAAGGATGGA
AAAAAAGTTCCATGTAAAATGCTGCTTCTTAGGGACTATGTAATAGTTGAGGGGGTGCATGAGCTGTTTTACCTTGATTT
TGGTGATGGCAGGAGTGTAGAAGTTGTGAATCAGGCTCTTAGTTAG

Upstream 100 bases:

>100_bases
AGAATTGCTACTCTTTCCTTTAGGTATTCCTCTCTTGAGATGACTGAACAAGATAGACAGGTGAACCCTTTGGGCTTCCA
GATCACTTACTATAGGGCGG

Downstream 100 bases:

>100_bases
AATTTGTCGATAGTAGGTGCAGGATGGCTGACGAAATAAGGGGTTCTAGCAGCGGGGAGAACATTGAGGATAATGTTAAT
GTAGTAGGTGTAGCAAAGAG

Product: type IV secretion system protein VirB9

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MMNFYKNFYVALVTAFALFSMSKACFASTNIGVPVSVDSRIKTFVYSQNEVFPVVFNYGYHSYIEFSQGETVRVMALGDN
ANWKIRPVDNKLYVMPLEKEGHTNMLIETSKGRSYAFDLISTAIPLSGGAASSINKLGKTNSALADLAYVVRFYYPQSDR
NFDIMGQKLEISPPSLASSLDADDVEIEPNATRTNYMFTGGSAHVSLAPTQAFDDGYLTYFQFGKNNKEIPKIYVVKKDG
KKVPCKMLLLRDYVIVEGVHELFYLDFGDGRSVEVVNQALS

Sequences:

>Translated_281_residues
MMNFYKNFYVALVTAFALFSMSKACFASTNIGVPVSVDSRIKTFVYSQNEVFPVVFNYGYHSYIEFSQGETVRVMALGDN
ANWKIRPVDNKLYVMPLEKEGHTNMLIETSKGRSYAFDLISTAIPLSGGAASSINKLGKTNSALADLAYVVRFYYPQSDR
NFDIMGQKLEISPPSLASSLDADDVEIEPNATRTNYMFTGGSAHVSLAPTQAFDDGYLTYFQFGKNNKEIPKIYVVKKDG
KKVPCKMLLLRDYVIVEGVHELFYLDFGDGRSVEVVNQALS
>Mature_281_residues
MMNFYKNFYVALVTAFALFSMSKACFASTNIGVPVSVDSRIKTFVYSQNEVFPVVFNYGYHSYIEFSQGETVRVMALGDN
ANWKIRPVDNKLYVMPLEKEGHTNMLIETSKGRSYAFDLISTAIPLSGGAASSINKLGKTNSALADLAYVVRFYYPQSDR
NFDIMGQKLEISPPSLASSLDADDVEIEPNATRTNYMFTGGSAHVSLAPTQAFDDGYLTYFQFGKNNKEIPKIYVVKKDG
KKVPCKMLLLRDYVIVEGVHELFYLDFGDGRSVEVVNQALS

Specific function: Component of the type IV secretion system virB/virD4 which could be a major virulence determinant for subversion of human endothelial cell (HEC) function [H]

COG id: COG3504

COG function: function code U; Type IV secretory pathway, VirB9 components

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trbG/virB9 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010258
- InterPro:   IPR014148 [H]

Pfam domain/function: PF03524 CagX [H]

EC number: NA

Molecular weight: Translated: 31373; Mature: 31373

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNFYKNFYVALVTAFALFSMSKACFASTNIGVPVSVDSRIKTFVYSQNEVFPVVFNYGY
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCEEEEEEECCC
HSYIEFSQGETVRVMALGDNANWKIRPVDNKLYVMPLEKEGHTNMLIETSKGRSYAFDLI
EEEEEECCCCEEEEEEECCCCCEEEEEECCEEEEEEECCCCCCEEEEEECCCCEEEHHHH
STAIPLSGGAASSINKLGKTNSALADLAYVVRFYYPQSDRNFDIMGQKLEISPPSLASSL
HHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHEECCCCCCCEEEECCEEECCCCHHHHCC
DADDVEIEPNATRTNYMFTGGSAHVSLAPTQAFDDGYLTYFQFGKNNKEIPKIYVVKKDG
CCCCEEECCCCCEEEEEEECCCEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEEEECCC
KKVPCKMLLLRDYVIVEGVHELFYLDFGDGRSVEVVNQALS
CCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHCC
>Mature Secondary Structure
MMNFYKNFYVALVTAFALFSMSKACFASTNIGVPVSVDSRIKTFVYSQNEVFPVVFNYGY
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCEEEEEEECCC
HSYIEFSQGETVRVMALGDNANWKIRPVDNKLYVMPLEKEGHTNMLIETSKGRSYAFDLI
EEEEEECCCCEEEEEEECCCCCEEEEEECCEEEEEEECCCCCCEEEEEECCCCEEEHHHH
STAIPLSGGAASSINKLGKTNSALADLAYVVRFYYPQSDRNFDIMGQKLEISPPSLASSL
HHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHEECCCCCCCEEEECCEEECCCCHHHHCC
DADDVEIEPNATRTNYMFTGGSAHVSLAPTQAFDDGYLTYFQFGKNNKEIPKIYVVKKDG
CCCCEEECCCCCEEEEEEECCCEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEEEECCC
KKVPCKMLLLRDYVIVEGVHELFYLDFGDGRSVEVVNQALS
CCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA