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The map label for this gene is folB

Identifier: 88607213

GI number: 88607213

Start: 653978

End: 654328

Strand: Direct

Name: folB

Synonym: APH_0628

Alternate gene names: NA

Gene position: 653978-654328 (Clockwise)

Preceding gene: 88607637

Following gene: 88607793

Centisome position: 44.45

GC content: 37.32

Gene sequence:

>351_bases
GTGGTTTTTCAGCTAAATATTGAAGATCTAGTGGTCTTTATGTGCATAGGAGTTTACAACTGGGAAAGAATAATCAAGCA
AAAAGTCTATGTAAGTATAAATGTAACGTATAGCAGCGAGCAAGGTGGTGAGTTCTTGGATTATGATACCTTTAGTCAAA
GAATCATTGAATTACTTACGGCAAAAGATTACCTCCTTTTGGAGGATGCAATATCCGATGTAATATCGTTTATAGTTTTG
GAGCACGAGACAACGTTGGCATGCGAGGTGAAAATCTATAAGCCAGTAGTGTCTTTTCTCCGGGATTCAAAGAGTATTTC
TATCTCTGCTATATGGAATAAGGACAGGTAG

Upstream 100 bases:

>100_bases
TGTCAGTAACTTATGTAAAGGCTTTTGCATATGTATTCTCCTAGACAAAGCGCTTAATGTCGCATTTTATACTAACTGAT
ACCTATCTAGAGAGAATTTT

Downstream 100 bases:

>100_bases
GGAAGCCTGCTTGACAAGTATAGAAGGCCTGCTATACTCCGAGGGTTTTTGTTTTTCACATTGTGGCTATGCGGTCTCAT
CGTTCAGTAAAAGTTTCATT

Product: dihydroneopterin aldolase

Products: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine; glycolaldehyde

Alternate protein names: NA

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MVFQLNIEDLVVFMCIGVYNWERIIKQKVYVSINVTYSSEQGGEFLDYDTFSQRIIELLTAKDYLLLEDAISDVISFIVL
EHETTLACEVKIYKPVVSFLRDSKSISISAIWNKDR

Sequences:

>Translated_116_residues
MVFQLNIEDLVVFMCIGVYNWERIIKQKVYVSINVTYSSEQGGEFLDYDTFSQRIIELLTAKDYLLLEDAISDVISFIVL
EHETTLACEVKIYKPVVSFLRDSKSISISAIWNKDR
>Mature_116_residues
MVFQLNIEDLVVFMCIGVYNWERIIKQKVYVSINVTYSSEQGGEFLDYDTFSQRIIELLTAKDYLLLEDAISDVISFIVL
EHETTLACEVKIYKPVVSFLRDSKSISISAIWNKDR

Specific function: Unknown

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.1.2.25

Molecular weight: Translated: 13467; Mature: 13467

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFQLNIEDLVVFMCIGVYNWERIIKQKVYVSINVTYSSEQGGEFLDYDTFSQRIIELLT
CEEEECHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
AKDYLLLEDAISDVISFIVLEHETTLACEVKIYKPVVSFLRDSKSISISAIWNKDR
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHCCCCEEEEEEECCCC
>Mature Secondary Structure
MVFQLNIEDLVVFMCIGVYNWERIIKQKVYVSINVTYSSEQGGEFLDYDTFSQRIIELLT
CEEEECHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
AKDYLLLEDAISDVISFIVLEHETTLACEVKIYKPVVSFLRDSKSISISAIWNKDR
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-; $dihydropteridine

Specific reaction: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8- $dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA