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The map label for this gene is pkn1 [H]

Identifier: 87200487

GI number: 87200487

Start: 2673478

End: 2674410

Strand: Direct

Name: pkn1 [H]

Synonym: Saro_2474

Alternate gene names: 87200487

Gene position: 2673478-2674410 (Clockwise)

Preceding gene: 87200486

Following gene: 87200490

Centisome position: 75.06

GC content: 62.49

Gene sequence:

>933_bases
ATGGTCGAACGCCCCGGCATGCGCCTGATCGAAGGCGGCACTTTCACCATGGGCTCGGAAGCCTTCTACCCGGAGGAAGC
GCCGCTTCGCCGGGTGAAGGTAGACAGCTTCTGGATCGATGAAGCGCCGGTGACGAACGCACAGTTCGCCGCATTCGTGG
AGGCCACGGGATACGTCACTGTGGCCGAGATCGAGCCGGATCCCAAGGACTACCCCGGCATGCTCCCGGGCATGGACCGC
GCGGGATCGCTGGTGTTCCAGAAAACAGCAGGGCCGGTCGACATGGCGGATGCGTCCAACTGGTGGCACTTTACCTTTGG
CGCCTGCTGGAAGCATCCACTTGGACCGGGCAGTTCCATCGATGGGATCGAGGACCATCCCGTCGTTCACGTCGCCTATG
CCGATGCCGAGGCCTATGCCAAATGGGCGGGCAAGGATCTGCCGACCGAAGCCGAGTTCGAATATGCTGCGCGCGGCGGG
TTGGACGGTTCCGAATTTTCCTGGGGAGACGAACTCGCACCTGAAGGCCGGATGATGGCCAACTACTGGCAAGGCCTGTT
TCCCTTCGCCAACCAGTGCCTCGATGGCTGGGAACGGACATCGCCCGTCCGCAACTTCCCGCCCAACGGCTATGGTCTTT
ACGACATGATCGGGAACACGTGGGAGTGGACCTGCGATTGGTGGGCCGACAAGCCGCTGACTCCGCAAAGGAAATCGGCA
TGCTGCGCGATCAGCAATCCGCGCGGCGGCAAGCTCAAGGACAGCTTCGACCCGTCGCAACCCGCAATGCGCATCGGCCG
GAAGGTCATAAAGGGCGGTTCGCACCTGTGTGCGGCCAATTACTGCCAGCGCTATCGCCCCGCAGCACGCCATCCTGAAA
TGGTTGATACCGCGACGACGCACATCGGCTTCAGGTGTGTGGTGCGGCCCTGA

Upstream 100 bases:

>100_bases
GAGGCCATTTTCATCAATGGCGCAACCATTCCGATCGACGGCGGCCAGTCGTACAAGTATTGAACGCCATCTCGAACCCA
ATTGCAGGAGCACGTCGCGA

Downstream 100 bases:

>100_bases
AGCTTGCGCAAATTCGGATTGGCGCTGCGGTGCCCACGACAGGCACCGCCGGCTGGGGATTACGCGCCTGCGAGCATCAG
CATGGTCGCACGGCCCAATC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MVERPGMRLIEGGTFTMGSEAFYPEEAPLRRVKVDSFWIDEAPVTNAQFAAFVEATGYVTVAEIEPDPKDYPGMLPGMDR
AGSLVFQKTAGPVDMADASNWWHFTFGACWKHPLGPGSSIDGIEDHPVVHVAYADAEAYAKWAGKDLPTEAEFEYAARGG
LDGSEFSWGDELAPEGRMMANYWQGLFPFANQCLDGWERTSPVRNFPPNGYGLYDMIGNTWEWTCDWWADKPLTPQRKSA
CCAISNPRGGKLKDSFDPSQPAMRIGRKVIKGGSHLCAANYCQRYRPAARHPEMVDTATTHIGFRCVVRP

Sequences:

>Translated_310_residues
MVERPGMRLIEGGTFTMGSEAFYPEEAPLRRVKVDSFWIDEAPVTNAQFAAFVEATGYVTVAEIEPDPKDYPGMLPGMDR
AGSLVFQKTAGPVDMADASNWWHFTFGACWKHPLGPGSSIDGIEDHPVVHVAYADAEAYAKWAGKDLPTEAEFEYAARGG
LDGSEFSWGDELAPEGRMMANYWQGLFPFANQCLDGWERTSPVRNFPPNGYGLYDMIGNTWEWTCDWWADKPLTPQRKSA
CCAISNPRGGKLKDSFDPSQPAMRIGRKVIKGGSHLCAANYCQRYRPAARHPEMVDTATTHIGFRCVVRP
>Mature_310_residues
MVERPGMRLIEGGTFTMGSEAFYPEEAPLRRVKVDSFWIDEAPVTNAQFAAFVEATGYVTVAEIEPDPKDYPGMLPGMDR
AGSLVFQKTAGPVDMADASNWWHFTFGACWKHPLGPGSSIDGIEDHPVVHVAYADAEAYAKWAGKDLPTEAEFEYAARGG
LDGSEFSWGDELAPEGRMMANYWQGLFPFANQCLDGWERTSPVRNFPPNGYGLYDMIGNTWEWTCDWWADKPLTPQRKSA
CCAISNPRGGKLKDSFDPSQPAMRIGRKVIKGGSHLCAANYCQRYRPAARHPEMVDTATTHIGFRCVVRP

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=305, Percent_Identity=42.6229508196721, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI257470975, Length=305, Percent_Identity=40, Blast_Score=218, Evalue=6e-57,
Organism=Homo sapiens, GI257470977, Length=305, Percent_Identity=40.327868852459, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI194248088, Length=307, Percent_Identity=34.8534201954397, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI194248087, Length=307, Percent_Identity=33.5504885993485, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI226437577, Length=211, Percent_Identity=37.914691943128, Blast_Score=128, Evalue=5e-30,
Organism=Homo sapiens, GI194248090, Length=248, Percent_Identity=35.4838709677419, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI20130397, Length=303, Percent_Identity=40.2640264026403, Blast_Score=202, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 34431; Mature: 34431

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVERPGMRLIEGGTFTMGSEAFYPEEAPLRRVKVDSFWIDEAPVTNAQFAAFVEATGYVT
CCCCCCCEEEECCCEEECCCCCCCCCCCCEEEEECEEECCCCCCCCCHHEEEEEECCCEE
VAEIEPDPKDYPGMLPGMDRAGSLVFQKTAGPVDMADASNWWHFTFGACWKHPLGPGSSI
EEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEHHHHHCCCCCCCCCC
DGIEDHPVVHVAYADAEAYAKWAGKDLPTEAEFEYAARGGLDGSEFSWGDELAPEGRMMA
CCCCCCCEEEEEECCHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHH
NYWQGLFPFANQCLDGWERTSPVRNFPPNGYGLYDMIGNTWEWTCDWWADKPLTPQRKSA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCEEEEEEECCCCCCCCCCCCC
CCAISNPRGGKLKDSFDPSQPAMRIGRKVIKGGSHLCAANYCQRYRPAARHPEMVDTATT
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHH
HIGFRCVVRP
CCCEEEEECC
>Mature Secondary Structure
MVERPGMRLIEGGTFTMGSEAFYPEEAPLRRVKVDSFWIDEAPVTNAQFAAFVEATGYVT
CCCCCCCEEEECCCEEECCCCCCCCCCCCEEEEECEEECCCCCCCCCHHEEEEEECCCEE
VAEIEPDPKDYPGMLPGMDRAGSLVFQKTAGPVDMADASNWWHFTFGACWKHPLGPGSSI
EEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEHHHHHCCCCCCCCCC
DGIEDHPVVHVAYADAEAYAKWAGKDLPTEAEFEYAARGGLDGSEFSWGDELAPEGRMMA
CCCCCCCEEEEEECCHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHH
NYWQGLFPFANQCLDGWERTSPVRNFPPNGYGLYDMIGNTWEWTCDWWADKPLTPQRKSA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCEEEEEEECCCCCCCCCCCCC
CCAISNPRGGKLKDSFDPSQPAMRIGRKVIKGGSHLCAANYCQRYRPAARHPEMVDTATT
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHH
HIGFRCVVRP
CCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]