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The map label for this gene is gap [H]

Identifier: 87199984

GI number: 87199984

Start: 2084730

End: 2085737

Strand: Reverse

Name: gap [H]

Synonym: Saro_1967

Alternate gene names: 87199984

Gene position: 2085737-2084730 (Counterclockwise)

Preceding gene: 87199985

Following gene: 87199983

Centisome position: 58.56

GC content: 62.5

Gene sequence:

>1008_bases
ATGGCGATCAAGGTTGCGATCAACGGTTTCGGACGCATCGGGCGCAATGTGGCCCGCGCCATTCTCGAACGTCCCGATTG
CGGGCTCGAACTGGTTTCGATCAACGACCTGGCCGACGCCAAGGCTAACGCCCTGCTGTTCAAGCGCGACAGCGTCCATG
GCGCGTTCTCGGGCGAAGTCTCGGTCGATGGCAACGACCTGATCGTCAACGGCAAGCGCATCCAGGTGACTGCCGAGCGC
GACCCGGCCAACCTGCCGCACGGAGCCAACGGCATTGACATCGCGCTGGAATGCACCGGCTTTTTCACCAATCGCGATGG
CGGCCAGAAGCACCTCGACGCCGGCGCCAAGCGCGTTCTGATTTCCGCTCCGGCAAAGAACGTCGACCTGACGGTCGTCT
ATGGCGTGAACCACGACAAGCTGACCGGCGATCACAAGATCGTCTCCAACGCGTCGTGCACCACCAACTGCCTCGCGCCG
ATGGCCAAGGTCCTGCATGAATCGATCGGGATCGAGCGTGGTCTGATGACCACGATCCATTCGTACACCAACGACCAGAA
GATCCTCGACCAGATCCACAGCGATCCGCGCCGCGCCCGCGCAGCCGCGATGAACATGATCCCCACCAGCACCGGCGCCG
CCGTTGCAGTGGGTGAAGTTCTGCCCGACCTCAAGGGCAAGCTTGACGGTTCGTCGATCCGCGTCCCGACCCCGAACGTC
TCGGTCGTGGACCTTACCTTCACGCCGAAGCGCGACACCTCGGTCGAGGAAGTCAACGGTCTCCTCAAGGCGGCTGCCGA
AGGCGCACTCAAGGGCGTGCTTGGCTACACCGACGAACCGCTGGTTTCGATCGACTTTAACCACGATCCGCATTCGTCGA
CCATCGACAGCCTTGAGACTGCCGTGCTCGAAGGCAAGCTGGTCCGCGTCCTGTCGTGGTACGACAACGAGTGGGGCTTC
TCCAACCGCATGCTCGACACGGCGGGCGCAATGGCGAAGTTCCTCTGA

Upstream 100 bases:

>100_bases
CCCCGGCCGAAGTGCTGTTCGACCACTTTGGCCTCACGGCTGAAAAGATTGTCCCGCAGATTCTCGCGCGGGTTTCGTAA
TTCAACAGGAGAAAGCTGAC

Downstream 100 bases:

>100_bases
GGAACGGTTGACATGAGCGGGCGTCTTGGTGGCATTGCACGGCACGACAGGCCGCGCGGGGCCGTCGAGACGCTCGATCA
TGTTTCGGTCTCTCGCGAAC

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MAIKVAINGFGRIGRNVARAILERPDCGLELVSINDLADAKANALLFKRDSVHGAFSGEVSVDGNDLIVNGKRIQVTAER
DPANLPHGANGIDIALECTGFFTNRDGGQKHLDAGAKRVLISAPAKNVDLTVVYGVNHDKLTGDHKIVSNASCTTNCLAP
MAKVLHESIGIERGLMTTIHSYTNDQKILDQIHSDPRRARAAAMNMIPTSTGAAVAVGEVLPDLKGKLDGSSIRVPTPNV
SVVDLTFTPKRDTSVEEVNGLLKAAAEGALKGVLGYTDEPLVSIDFNHDPHSSTIDSLETAVLEGKLVRVLSWYDNEWGF
SNRMLDTAGAMAKFL

Sequences:

>Translated_335_residues
MAIKVAINGFGRIGRNVARAILERPDCGLELVSINDLADAKANALLFKRDSVHGAFSGEVSVDGNDLIVNGKRIQVTAER
DPANLPHGANGIDIALECTGFFTNRDGGQKHLDAGAKRVLISAPAKNVDLTVVYGVNHDKLTGDHKIVSNASCTTNCLAP
MAKVLHESIGIERGLMTTIHSYTNDQKILDQIHSDPRRARAAAMNMIPTSTGAAVAVGEVLPDLKGKLDGSSIRVPTPNV
SVVDLTFTPKRDTSVEEVNGLLKAAAEGALKGVLGYTDEPLVSIDFNHDPHSSTIDSLETAVLEGKLVRVLSWYDNEWGF
SNRMLDTAGAMAKFL
>Mature_334_residues
AIKVAINGFGRIGRNVARAILERPDCGLELVSINDLADAKANALLFKRDSVHGAFSGEVSVDGNDLIVNGKRIQVTAERD
PANLPHGANGIDIALECTGFFTNRDGGQKHLDAGAKRVLISAPAKNVDLTVVYGVNHDKLTGDHKIVSNASCTTNCLAPM
AKVLHESIGIERGLMTTIHSYTNDQKILDQIHSDPRRARAAAMNMIPTSTGAAVAVGEVLPDLKGKLDGSSIRVPTPNVS
VVDLTFTPKRDTSVEEVNGLLKAAAEGALKGVLGYTDEPLVSIDFNHDPHSSTIDSLETAVLEGKLVRVLSWYDNEWGFS
NRMLDTAGAMAKFL

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=332, Percent_Identity=47.5903614457831, Blast_Score=303, Evalue=2e-82,
Organism=Homo sapiens, GI7657116, Length=327, Percent_Identity=45.8715596330275, Blast_Score=278, Evalue=6e-75,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=48.8023952095808, Blast_Score=333, Evalue=8e-93,
Organism=Escherichia coli, GI1788079, Length=334, Percent_Identity=52.3952095808383, Blast_Score=333, Evalue=9e-93,
Organism=Caenorhabditis elegans, GI17534677, Length=337, Percent_Identity=48.0712166172107, Blast_Score=296, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI17534679, Length=337, Percent_Identity=47.7744807121662, Blast_Score=296, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI32566163, Length=337, Percent_Identity=47.1810089020772, Blast_Score=284, Evalue=5e-77,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=47.1810089020772, Blast_Score=283, Evalue=7e-77,
Organism=Saccharomyces cerevisiae, GI6321631, Length=333, Percent_Identity=53.7537537537538, Blast_Score=346, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6322468, Length=333, Percent_Identity=52.8528528528528, Blast_Score=337, Evalue=1e-93,
Organism=Saccharomyces cerevisiae, GI6322409, Length=333, Percent_Identity=51.9519519519519, Blast_Score=333, Evalue=3e-92,
Organism=Drosophila melanogaster, GI17933600, Length=325, Percent_Identity=50.4615384615385, Blast_Score=308, Evalue=2e-84,
Organism=Drosophila melanogaster, GI18110149, Length=325, Percent_Identity=50.4615384615385, Blast_Score=308, Evalue=2e-84,
Organism=Drosophila melanogaster, GI85725000, Length=325, Percent_Identity=49.5384615384615, Blast_Score=308, Evalue=4e-84,
Organism=Drosophila melanogaster, GI22023983, Length=325, Percent_Identity=49.5384615384615, Blast_Score=308, Evalue=4e-84,
Organism=Drosophila melanogaster, GI19922412, Length=324, Percent_Identity=47.5308641975309, Blast_Score=293, Evalue=1e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35771; Mature: 35640

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKVAINGFGRIGRNVARAILERPDCGLELVSINDLADAKANALLFKRDSVHGAFSGEV
CEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCEECCEE
SVDGNDLIVNGKRIQVTAERDPANLPHGANGIDIALECTGFFTNRDGGQKHLDAGAKRVL
EECCCEEEEECEEEEEEECCCCCCCCCCCCCEEEEEEEEEEEECCCCCHHHHCCCCCEEE
ISAPAKNVDLTVVYGVNHDKLTGDHKIVSNASCTTNCLAPMAKVLHESIGIERGLMTTIH
EECCCCCCEEEEEEECCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
SYTNDQKILDQIHSDPRRARAAAMNMIPTSTGAAVAVGEVLPDLKGKLDGSSIRVPTPNV
HCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCCCEEEECCCCC
SVVDLTFTPKRDTSVEEVNGLLKAAAEGALKGVLGYTDEPLVSIDFNHDPHSSTIDSLET
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHH
AVLEGKLVRVLSWYDNEWGFSNRMLDTAGAMAKFL
HHHHHHHEEEEEHHCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
AIKVAINGFGRIGRNVARAILERPDCGLELVSINDLADAKANALLFKRDSVHGAFSGEV
EEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCEECCEE
SVDGNDLIVNGKRIQVTAERDPANLPHGANGIDIALECTGFFTNRDGGQKHLDAGAKRVL
EECCCEEEEECEEEEEEECCCCCCCCCCCCCEEEEEEEEEEEECCCCCHHHHCCCCCEEE
ISAPAKNVDLTVVYGVNHDKLTGDHKIVSNASCTTNCLAPMAKVLHESIGIERGLMTTIH
EECCCCCCEEEEEEECCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
SYTNDQKILDQIHSDPRRARAAAMNMIPTSTGAAVAVGEVLPDLKGKLDGSSIRVPTPNV
HCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCCCEEEECCCCC
SVVDLTFTPKRDTSVEEVNGLLKAAAEGALKGVLGYTDEPLVSIDFNHDPHSSTIDSLET
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHH
AVLEGKLVRVLSWYDNEWGFSNRMLDTAGAMAKFL
HHHHHHHEEEEEHHCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3680173 [H]