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The map label for this gene is ykoU [H]

Identifier: 87199712

GI number: 87199712

Start: 1779469

End: 1782000

Strand: Direct

Name: ykoU [H]

Synonym: Saro_1695

Alternate gene names: 87199712

Gene position: 1779469-1782000 (Clockwise)

Preceding gene: 87199711

Following gene: 87199716

Centisome position: 49.96

GC content: 66.35

Gene sequence:

>2532_bases
ATGGGGCGCAACGATCCGCTCGCCGCCTACAACGCCAAGCGCGACTTCGCGCGCACTGCGGAACCTGCCGGCAAGCGCAA
GTCCAGCGCCACGGGCAATCTCTTCATCGTCCAGAAGCACGACGCCACCCGCCTGCACTGGGACTTCCGCATGGAGGTTG
ATGGCGTGCTCAAGAGTTGGGCCGTGACCCGGGGCCCTAGCCCCGATCCCGACGACAAGCGCCTCGCTGTCCAGACCGAG
GACCACCCCCTCGAATACGCCCGGTTCGAAGGCATCATCCCCGAAGGCGAGTACGGGGGCGGCACCGTCATGCTCTGGGA
CAAGGGCACCTGGGAGCCGGTCGAGGGCAAGAGCGCCAAGGATCTGGAAAAGGGGCACCTCCATTTCCGCCTCGAGGGGG
AGCGGATGAAGGGCGAATGGCTGCTTGTCCGCCTCAAGCGTCGCGGCAATGAAAAGCGCGACAACTGGCTCCTGCGCAAG
CTGGACGACGCCTATGCGGGCCAGGGCGACCAGCTCGTCGAGCGCGGCCTGACCAGCGTCCTCACCGGCCGCACCATGGC
CGAAATCGCCTCCGACAAGGCTGGCAGCCATTCGCTCAAAGGCAAGCGCGGCAAGGCCTTCGCTTCGGTGATGGAAGAAG
CAGGCACGCATAACCGCAAGGTCGGCAAGGCGCGCGGCAAGGCACCGTCCAGGGCGCGCCGGAACGCACCGCTACCCGCC
TTCCAGCCCGTCCAGCTCGCAACCCTGGTCGATACGGTGCCCGATGGGCGCCAATGGCTGTACGAGATCAAGTTCGACGG
CTACCGCGCGCTCGTCGCAGTGCGGGGAACCGAGGTCCGCGTCTTCACCCGCAGCGGTCTCGACTGGACCGAAAAGTTCG
CGCCGCTTGCCCGCCATCTCGCCGGGCTCAAGCTGCCGTCGTGCCTGATCGACGGCGAGATCGTCGCCGCCGATGCCGAT
GGCAATCCCGATTTCTCGCGGCTTCAAGCCGTGCTCAAGCGCGGGCATGGCGAACAGGGCGAGGGTGATGCCTTGTCGTT
CCACGCCTTCGACTTGCTGGAACTCGAAGGCGAAGACCTGAAGCCCCTGCCCAATGTAGAGCGCAAGCAGAAGCTCGCCG
CGCTGCTTGCCGGGGTCTCGCCGCCGATCCACGTCGCCGACCACATCATCGGCGGCGGCGAAAAGCTGCTTGGCGCGCTG
TGCGGCGCGGGGCAGGAAGGGATCATCTGCAAGCGCGCGGACGCGGCCTATGCGGGCAAGCGGACGCAGAACTGGCTGAA
GGTGAAGTGCGTGGCCCGCCAGGAATTCATCGTCGTCGGCTTCACCCGGTCCAGCGCCCGCCGCCGCCCTTTCGCCTCGC
TTCTCCTGGCCCAGCGCGAGGGAAAGGCGCTGGTCTACAAGGGCAAGGTGGGCACCGGCTTTGACGAGGACCTGCTGCAA
GACCTCGCCACCCGGTTCGAAGCCCTCAAGGTCGACGAAGGTCCGCTCGATGTGCCCATAACCGAAGCGCGCGGCGTGAC
CTGGCTGAAACCCGAACTCGTCGCGGAAATCGCCTTTGCCGAATTTACCGCCGAAGGCCGTGTCCGCCACGCCAGCTTCG
TCGGTCTGCGCGAAGACAAGAAGGCCGCGGACGTCGTCCCCGAACGGCCCGCCCCGCTGGTCGTTCAGCCGGAAATCGTG
CCGATCAGCAATCGCGAGCGGGTGATCTTTCCCGAAAGCGGCCAGACCAAGGGCGACCTTGCCGATTACTACGCCGCGAT
GGCGCCCGCGATGCTCCCGTTCATCGCCAACCGCCCCGTCAGCCTCGTCCGCTGTCCTCAGGGGCGCGCGCGCCACTGCT
TCTTCCAGAAGCACGATAGCGGCTCGTTCGGCGAACACGTCCACCACGTTCCGATCCGCGAGAAGGATGGCAACGAGGAG
GAGTATCTGTTCGTCAGTGACGCCGCCGGCATTCTCTCGTGCGTGCAGATGGGCACGATCGAGTTCCACGGCTGGTGTTC
TCTGGCAAGCGATGTCGAGGCGCCCGAACGGATGGTCATCGACCTCGATCCCGACGAGGGGCTCGATTTCAACGACGTCA
AGCGCGCCGCCCGCGATATTCGTGACCGCCTGTCCGACCTCGGTCTCGTCAGCTTTGCCATGCTTTCCGGCGGCAAGGGC
GTTCACGTCGTCGTGCCGCTGCGGCCCGACCACACCTGGGAGGCTCACGCCAGCTTTGCCGAACGTTTTGCCCGCGCGCT
CGCCCTGGCGGAACCCGATCGCTACGTCGCAACGATGAGCAAGGCCAGGCGCAAGGGCCGCATCTTCATCGACTGGCTCC
GCAACCGGCGCGGCAGCACCGCTGTCATGCCCTATTCGGCGCGCGCCCGCGCCAACGCTCCCGTCGCGGTGCCGATCGCC
TGGGAGGAACTCGACGACTTCGCGAACGCCCACCCCTTCTGCATCGGCGATACGGCAGGACTACTCAAGCGTAGCGAAGG
CAAGTCGCTGCGCGGCTGGGGAATGGCCCAACAGTCCCTCCCGGACGTTTAG

Upstream 100 bases:

>100_bases
TGCGCTCAAGAAGTCGCTGGGCGAGGGCAATGCCGGGGAAGGCGAGGGCCGTCCTCGCCGCAAGGCCGCCGCGCCCCGCG
CACGCAAGCGGGCGTGAGCC

Downstream 100 bases:

>100_bases
GGGCAGGACGCAGGTCTAGACCATGTCCCCCGGTCGGATAAGCCGGTCGAACGTCGCCTCGTCAACCAGTCCCAGCGCCA
GCGCCGCCTGTCGCAGGCTC

Product: ATP dependent DNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 843; Mature: 842

Protein sequence:

>843_residues
MGRNDPLAAYNAKRDFARTAEPAGKRKSSATGNLFIVQKHDATRLHWDFRMEVDGVLKSWAVTRGPSPDPDDKRLAVQTE
DHPLEYARFEGIIPEGEYGGGTVMLWDKGTWEPVEGKSAKDLEKGHLHFRLEGERMKGEWLLVRLKRRGNEKRDNWLLRK
LDDAYAGQGDQLVERGLTSVLTGRTMAEIASDKAGSHSLKGKRGKAFASVMEEAGTHNRKVGKARGKAPSRARRNAPLPA
FQPVQLATLVDTVPDGRQWLYEIKFDGYRALVAVRGTEVRVFTRSGLDWTEKFAPLARHLAGLKLPSCLIDGEIVAADAD
GNPDFSRLQAVLKRGHGEQGEGDALSFHAFDLLELEGEDLKPLPNVERKQKLAALLAGVSPPIHVADHIIGGGEKLLGAL
CGAGQEGIICKRADAAYAGKRTQNWLKVKCVARQEFIVVGFTRSSARRRPFASLLLAQREGKALVYKGKVGTGFDEDLLQ
DLATRFEALKVDEGPLDVPITEARGVTWLKPELVAEIAFAEFTAEGRVRHASFVGLREDKKAADVVPERPAPLVVQPEIV
PISNRERVIFPESGQTKGDLADYYAAMAPAMLPFIANRPVSLVRCPQGRARHCFFQKHDSGSFGEHVHHVPIREKDGNEE
EYLFVSDAAGILSCVQMGTIEFHGWCSLASDVEAPERMVIDLDPDEGLDFNDVKRAARDIRDRLSDLGLVSFAMLSGGKG
VHVVVPLRPDHTWEAHASFAERFARALALAEPDRYVATMSKARRKGRIFIDWLRNRRGSTAVMPYSARARANAPVAVPIA
WEELDDFANAHPFCIGDTAGLLKRSEGKSLRGWGMAQQSLPDV

Sequences:

>Translated_843_residues
MGRNDPLAAYNAKRDFARTAEPAGKRKSSATGNLFIVQKHDATRLHWDFRMEVDGVLKSWAVTRGPSPDPDDKRLAVQTE
DHPLEYARFEGIIPEGEYGGGTVMLWDKGTWEPVEGKSAKDLEKGHLHFRLEGERMKGEWLLVRLKRRGNEKRDNWLLRK
LDDAYAGQGDQLVERGLTSVLTGRTMAEIASDKAGSHSLKGKRGKAFASVMEEAGTHNRKVGKARGKAPSRARRNAPLPA
FQPVQLATLVDTVPDGRQWLYEIKFDGYRALVAVRGTEVRVFTRSGLDWTEKFAPLARHLAGLKLPSCLIDGEIVAADAD
GNPDFSRLQAVLKRGHGEQGEGDALSFHAFDLLELEGEDLKPLPNVERKQKLAALLAGVSPPIHVADHIIGGGEKLLGAL
CGAGQEGIICKRADAAYAGKRTQNWLKVKCVARQEFIVVGFTRSSARRRPFASLLLAQREGKALVYKGKVGTGFDEDLLQ
DLATRFEALKVDEGPLDVPITEARGVTWLKPELVAEIAFAEFTAEGRVRHASFVGLREDKKAADVVPERPAPLVVQPEIV
PISNRERVIFPESGQTKGDLADYYAAMAPAMLPFIANRPVSLVRCPQGRARHCFFQKHDSGSFGEHVHHVPIREKDGNEE
EYLFVSDAAGILSCVQMGTIEFHGWCSLASDVEAPERMVIDLDPDEGLDFNDVKRAARDIRDRLSDLGLVSFAMLSGGKG
VHVVVPLRPDHTWEAHASFAERFARALALAEPDRYVATMSKARRKGRIFIDWLRNRRGSTAVMPYSARARANAPVAVPIA
WEELDDFANAHPFCIGDTAGLLKRSEGKSLRGWGMAQQSLPDV
>Mature_842_residues
GRNDPLAAYNAKRDFARTAEPAGKRKSSATGNLFIVQKHDATRLHWDFRMEVDGVLKSWAVTRGPSPDPDDKRLAVQTED
HPLEYARFEGIIPEGEYGGGTVMLWDKGTWEPVEGKSAKDLEKGHLHFRLEGERMKGEWLLVRLKRRGNEKRDNWLLRKL
DDAYAGQGDQLVERGLTSVLTGRTMAEIASDKAGSHSLKGKRGKAFASVMEEAGTHNRKVGKARGKAPSRARRNAPLPAF
QPVQLATLVDTVPDGRQWLYEIKFDGYRALVAVRGTEVRVFTRSGLDWTEKFAPLARHLAGLKLPSCLIDGEIVAADADG
NPDFSRLQAVLKRGHGEQGEGDALSFHAFDLLELEGEDLKPLPNVERKQKLAALLAGVSPPIHVADHIIGGGEKLLGALC
GAGQEGIICKRADAAYAGKRTQNWLKVKCVARQEFIVVGFTRSSARRRPFASLLLAQREGKALVYKGKVGTGFDEDLLQD
LATRFEALKVDEGPLDVPITEARGVTWLKPELVAEIAFAEFTAEGRVRHASFVGLREDKKAADVVPERPAPLVVQPEIVP
ISNRERVIFPESGQTKGDLADYYAAMAPAMLPFIANRPVSLVRCPQGRARHCFFQKHDSGSFGEHVHHVPIREKDGNEEE
YLFVSDAAGILSCVQMGTIEFHGWCSLASDVEAPERMVIDLDPDEGLDFNDVKRAARDIRDRLSDLGLVSFAMLSGGKGV
HVVVPLRPDHTWEAHASFAERFARALALAEPDRYVATMSKARRKGRIFIDWLRNRRGSTAVMPYSARARANAPVAVPIAW
EELDDFANAHPFCIGDTAGLLKRSEGKSLRGWGMAQQSLPDV

Specific function: Probably involved in the repair of DNA double-strand breaks by non-homologous-end joining (NHEJ) during spore germination [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Homo sapiens, GI4557719, Length=329, Percent_Identity=27.0516717325228, Blast_Score=70, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324578, Length=242, Percent_Identity=28.099173553719, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR014145
- InterPro:   IPR014143 [H]

Pfam domain/function: PF01068 DNA_ligase_A_M [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 93006; Mature: 92875

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRNDPLAAYNAKRDFARTAEPAGKRKSSATGNLFIVQKHDATRLHWDFRMEVDGVLKSW
CCCCCCCEEECCCHHHHHCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEEEEHHHHHHHH
AVTRGPSPDPDDKRLAVQTEDHPLEYARFEGIIPEGEYGGGTVMLWDKGTWEPVEGKSAK
HHCCCCCCCCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCC
DLEKGHLHFRLEGERMKGEWLLVRLKRRGNEKRDNWLLRKLDDAYAGQGDQLVERGLTSV
CCCCCCEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LTGRTMAEIASDKAGSHSLKGKRGKAFASVMEEAGTHNRKVGKARGKAPSRARRNAPLPA
HCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHCCCCCHHHHCCCCCCC
FQPVQLATLVDTVPDGRQWLYEIKFDGYRALVAVRGTEVRVFTRSGLDWTEKFAPLARHL
CCCHHHHHHHHCCCCCCEEEEEEEECCEEEEEEEECCEEEEEEECCCCHHHHHHHHHHHH
AGLKLPSCLIDGEIVAADADGNPDFSRLQAVLKRGHGEQGEGDALSFHAFDLLELEGEDL
HCCCCCCEEECCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCCCC
KPLPNVERKQKLAALLAGVSPPIHVADHIIGGGEKLLGALCGAGQEGIICKRADAAYAGK
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCCCHHCCC
RTQNWLKVKCVARQEFIVVGFTRSSARRRPFASLLLAQREGKALVYKGKVGTGFDEDLLQ
CCCCEEEEEEEECCEEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHH
DLATRFEALKVDEGPLDVPITEARGVTWLKPELVAEIAFAEFTAEGRVRHASFVGLREDK
HHHHHHHEEECCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
KAADVVPERPAPLVVQPEIVPISNRERVIFPESGQTKGDLADYYAAMAPAMLPFIANRPV
CHHCCCCCCCCCEEECCEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCE
SLVRCPQGRARHCFFQKHDSGSFGEHVHHVPIREKDGNEEEYLFVSDAAGILSCVQMGTI
EEEECCCCCCCEEEEEECCCCCCCCCEEECCCCCCCCCCCCEEEEECHHHHHHHHHHCCE
EFHGWCSLASDVEAPERMVIDLDPDEGLDFNDVKRAARDIRDRLSDLGLVSFAMLSGGKG
EEECEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VHVVVPLRPDHTWEAHASFAERFARALALAEPDRYVATMSKARRKGRIFIDWLRNRRGST
EEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEHHHCCCCCE
AVMPYSARARANAPVAVPIAWEELDDFANAHPFCIGDTAGLLKRSEGKSLRGWGMAQQSL
EEECCCCCCCCCCCEEEEEEHHHHHHHCCCCCEEEECHHHHHCCCCCCCCCCCCCCHHCC
PDV
CCC
>Mature Secondary Structure 
GRNDPLAAYNAKRDFARTAEPAGKRKSSATGNLFIVQKHDATRLHWDFRMEVDGVLKSW
CCCCCCEEECCCHHHHHCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEEEEHHHHHHHH
AVTRGPSPDPDDKRLAVQTEDHPLEYARFEGIIPEGEYGGGTVMLWDKGTWEPVEGKSAK
HHCCCCCCCCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCC
DLEKGHLHFRLEGERMKGEWLLVRLKRRGNEKRDNWLLRKLDDAYAGQGDQLVERGLTSV
CCCCCCEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LTGRTMAEIASDKAGSHSLKGKRGKAFASVMEEAGTHNRKVGKARGKAPSRARRNAPLPA
HCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHCCCCCHHHHCCCCCCC
FQPVQLATLVDTVPDGRQWLYEIKFDGYRALVAVRGTEVRVFTRSGLDWTEKFAPLARHL
CCCHHHHHHHHCCCCCCEEEEEEEECCEEEEEEEECCEEEEEEECCCCHHHHHHHHHHHH
AGLKLPSCLIDGEIVAADADGNPDFSRLQAVLKRGHGEQGEGDALSFHAFDLLELEGEDL
HCCCCCCEEECCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCCCC
KPLPNVERKQKLAALLAGVSPPIHVADHIIGGGEKLLGALCGAGQEGIICKRADAAYAGK
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCCCHHCCC
RTQNWLKVKCVARQEFIVVGFTRSSARRRPFASLLLAQREGKALVYKGKVGTGFDEDLLQ
CCCCEEEEEEEECCEEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHH
DLATRFEALKVDEGPLDVPITEARGVTWLKPELVAEIAFAEFTAEGRVRHASFVGLREDK
HHHHHHHEEECCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
KAADVVPERPAPLVVQPEIVPISNRERVIFPESGQTKGDLADYYAAMAPAMLPFIANRPV
CHHCCCCCCCCCEEECCEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCE
SLVRCPQGRARHCFFQKHDSGSFGEHVHHVPIREKDGNEEEYLFVSDAAGILSCVQMGTI
EEEECCCCCCCEEEEEECCCCCCCCCEEECCCCCCCCCCCCEEEEECHHHHHHHHHHCCE
EFHGWCSLASDVEAPERMVIDLDPDEGLDFNDVKRAARDIRDRLSDLGLVSFAMLSGGKG
EEECEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VHVVVPLRPDHTWEAHASFAERFARALALAEPDRYVATMSKARRKGRIFIDWLRNRRGST
EEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEHHHCCCCCE
AVMPYSARARANAPVAVPIAWEELDDFANAHPFCIGDTAGLLKRSEGKSLRGWGMAQQSL
EEECCCCCCCCCCCEEEEEEHHHHHHHCCCCCEEEECHHHHHCCCCCCCCCCCCCCHHCC
PDV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]