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The map label for this gene is tauD [C]

Identifier: 87199563

GI number: 87199563

Start: 1599944

End: 1600894

Strand: Direct

Name: tauD [C]

Synonym: Saro_1546

Alternate gene names: 87199563

Gene position: 1599944-1600894 (Clockwise)

Preceding gene: 87199562

Following gene: 87199565

Centisome position: 44.92

GC content: 62.78

Gene sequence:

>951_bases
ATGACTGCCATCACCACTTATGCCAATGCCAAGGACCCCAACTCTCCTCTCGACATCGTTCCGGTCACAGGAACCATCGG
TGCGGAAATCCGCGGCGTGACGCTGTCCGGCGATCTTGATGCCGGGACCGTCCAGGCGATCAAGGATGCCGTCGTGCGCC
ACAAGGTCGTGTTCTTCCGCGGCCAGAAGGACCTTGACGATGCACGACATGAAGGCTTCGCCTCGTTGTTCGGAGAGCCG
GTCGCACATCCAACCGTGCCGGTCGCGGAAGGTTCGCGCTATCTGCTCGAACTCGACAGCAAGGAAGGCTACGCGGCCTC
GAGCTGGCACACCGACGTGACCTTCGTCGATTCCTATCCCAAGGGCTCGATCCTACGCGCGATCACTGTTCCTGAAGCGG
GCGGGGATACCGTCTGGGCGAATGGTGAAACCGCCTACGAAAGCCTACCGGAATCCCTTCGCCAACTGGTGAACAACCTT
TGGGCGGTCCACACCAACCTTTACGACTACGCCGCCGTCCTCAATGCACCCAAGGGCGACGAGACCGAGCGCGAGCGCGT
GAACTTCCACAAGAGCGTGTTCGCATCGACCGTCTACGAGACCGAGCACCCCGTGGTCCGCGTCCACCCCGTCTCGGGCC
AGCGCAGCCTGCTGCTGGGTCATTTCGTGAAGCAATTCGTCGGGCTCAACCAGGCGGACTCCTCGCGCCTGTTCCAGATC
CTGCAGGATCACATCACCCGGCCCGAAAACGTCGTGCGCTGGCGCTGGCAGCCGGGTGATGTGGCGTTCTGGGACAACCA
GTCGACCCAGCACCGTGCCGTCGCCGACTTTGGTCTGCAGCGTCGCACCCTGCGCCGCGCTACTATTGCAGGTGAAGTGC
CGGTCGGCATCGACGGTCGCCAGAGCCGTACCGTGCGGAAGGAAAAGGCCACCGAATACCAGCCCGCCTGA

Upstream 100 bases:

>100_bases
AGCAGCACGACGCCATTCGCCGCCACCTCGATACCGCAGCCGATCCTGCGCTCCAGCCGGCCGAATAACTCCCTGAAGCT
CAACACGAAGGAGCAAATCC

Downstream 100 bases:

>100_bases
TGGTTGGATGACCTGAGCAGGGCCTGCCCGAGGGCGGGCGGCGGGGTGGCAGACTCTCACTGCCACCCCGCAATTCCAAT
GGTTTCGAAAGCCGGGGCTT

Product: taurine dioxygenase

Products: Aminoacetaldehyde; CO2; H+; Sulfite; Succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTAITTYANAKDPNSPLDIVPVTGTIGAEIRGVTLSGDLDAGTVQAIKDAVVRHKVVFFRGQKDLDDARHEGFASLFGEP
VAHPTVPVAEGSRYLLELDSKEGYAASSWHTDVTFVDSYPKGSILRAITVPEAGGDTVWANGETAYESLPESLRQLVNNL
WAVHTNLYDYAAVLNAPKGDETERERVNFHKSVFASTVYETEHPVVRVHPVSGQRSLLLGHFVKQFVGLNQADSSRLFQI
LQDHITRPENVVRWRWQPGDVAFWDNQSTQHRAVADFGLQRRTLRRATIAGEVPVGIDGRQSRTVRKEKATEYQPA

Sequences:

>Translated_316_residues
MTAITTYANAKDPNSPLDIVPVTGTIGAEIRGVTLSGDLDAGTVQAIKDAVVRHKVVFFRGQKDLDDARHEGFASLFGEP
VAHPTVPVAEGSRYLLELDSKEGYAASSWHTDVTFVDSYPKGSILRAITVPEAGGDTVWANGETAYESLPESLRQLVNNL
WAVHTNLYDYAAVLNAPKGDETERERVNFHKSVFASTVYETEHPVVRVHPVSGQRSLLLGHFVKQFVGLNQADSSRLFQI
LQDHITRPENVVRWRWQPGDVAFWDNQSTQHRAVADFGLQRRTLRRATIAGEVPVGIDGRQSRTVRKEKATEYQPA
>Mature_315_residues
TAITTYANAKDPNSPLDIVPVTGTIGAEIRGVTLSGDLDAGTVQAIKDAVVRHKVVFFRGQKDLDDARHEGFASLFGEPV
AHPTVPVAEGSRYLLELDSKEGYAASSWHTDVTFVDSYPKGSILRAITVPEAGGDTVWANGETAYESLPESLRQLVNNLW
AVHTNLYDYAAVLNAPKGDETERERVNFHKSVFASTVYETEHPVVRVHPVSGQRSLLLGHFVKQFVGLNQADSSRLFQIL
QDHITRPENVVRWRWQPGDVAFWDNQSTQHRAVADFGLQRRTLRRATIAGEVPVGIDGRQSRTVRKEKATEYQPA

Specific function: Catalyzes The Conversion Of Taurine And Alpha Ketoglutarate To Sulfite, Aminoacetaldehyde And Succinate. Required For The Utilization Of Taurine (2-Aminoethanesulfonic Acid) As An Alternative Sulfur Source. Pentane-Sulfonic Acid, 3- (N-Morpholino)Propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=281, Percent_Identity=40.5693950177936, Blast_Score=196, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6322971, Length=307, Percent_Identity=25.7328990228013, Blast_Score=90, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: 1.14.11.17 [C]

Molecular weight: Translated: 35012; Mature: 34881

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAITTYANAKDPNSPLDIVPVTGTIGAEIRGVTLSGDLDAGTVQAIKDAVVRHKVVFFR
CCEEEECCCCCCCCCCEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHEEEEEE
GQKDLDDARHEGFASLFGEPVAHPTVPVAEGSRYLLELDSKEGYAASSWHTDVTFVDSYP
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCEECCCCCCEEEEECCC
KGSILRAITVPEAGGDTVWANGETAYESLPESLRQLVNNLWAVHTNLYDYAAVLNAPKGD
CCCEEEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ETERERVNFHKSVFASTVYETEHPVVRVHPVSGQRSLLLGHFVKQFVGLNQADSSRLFQI
CHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
LQDHITRPENVVRWRWQPGDVAFWDNQSTQHRAVADFGLQRRTLRRATIAGEVPVGIDGR
HHHHCCCCCCEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
QSRTVRKEKATEYQPA
CCHHHHHHHCCCCCCC
>Mature Secondary Structure 
TAITTYANAKDPNSPLDIVPVTGTIGAEIRGVTLSGDLDAGTVQAIKDAVVRHKVVFFR
CEEEECCCCCCCCCCEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHEEEEEE
GQKDLDDARHEGFASLFGEPVAHPTVPVAEGSRYLLELDSKEGYAASSWHTDVTFVDSYP
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCEECCCCCCEEEEECCC
KGSILRAITVPEAGGDTVWANGETAYESLPESLRQLVNNLWAVHTNLYDYAAVLNAPKGD
CCCEEEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ETERERVNFHKSVFASTVYETEHPVVRVHPVSGQRSLLLGHFVKQFVGLNQADSSRLFQI
CHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
LQDHITRPENVVRWRWQPGDVAFWDNQSTQHRAVADFGLQRRTLRRATIAGEVPVGIDGR
HHHHCCCCCCEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
QSRTVRKEKATEYQPA
CCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Ascorbate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; O2; Taurine [C]

Specific reaction: 2-Oxoglutarate + O2 + Taurine --> Aminoacetaldehyde + CO2 + H+ + Sulfite + Succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]