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The map label for this gene is murC [H]

Identifier: 87199446

GI number: 87199446

Start: 1466398

End: 1467825

Strand: Reverse

Name: murC [H]

Synonym: Saro_1425

Alternate gene names: 87199446

Gene position: 1467825-1466398 (Counterclockwise)

Preceding gene: 87199452

Following gene: 87199444

Centisome position: 41.21

GC content: 65.83

Gene sequence:

>1428_bases
ATGACGAACACCGCGCTCCCCACGCCCTCCTCACTTGCCGATCACGACTGGTTCTTCTGCGGCATCGGGGGATCCGGCAT
GCTGCCGCTCGCATTGATCCTGCGTGGCAAGGGCGCTCGCGTCGCAGGGTCGGACCGCAGCCGCGACCAGGGACGGACGC
CGGAAAAATTCGCGTGGCTCGAAGCCTGCGGGTTTTCGCTGTTTCCGCAGGACGGCACTGGCATTTCCTCGCCGGACCAG
ATCCTCGTGGCCTCGGCGGCGGTCGAGGATACCGTGCCCGAAGTCGTTCGCGCGCGGGAACTCGGCTGCGCGCGGATGAG
CCGGGCCGAGCTCCTCTCCGCCCTGTTCAATACCGCACCGGTCGGCGTGGCCGTCGGCGGCACCAGCGGAAAATCCACCG
TCACCGGCATGACCGGCTGGATCCTGACCTACGCCGGGCGAGATCCGACCATCATGAACGGCGCGGTGATGAAGAACTTC
GTCGCGCCCGATGCGCCGTTCGCGTCGGCCAGGGTCGGCAAGGGCGAGGCATTCGTCTCCGAGGTCGATGAGAGTGACGG
GTCGATCGCACTCTACAATCCTGCGATCGCCGTGCTCAACAATGTCAGCCTCGACCACAAGAGCCTTGAAGAATTGCGCG
AACTGTTCGGCGACTTCCTGGCACGCGCAGACACCGCAGTCGTCAACGCAGATGACCCGGAAAGCCTTGCCCTGATCGGC
CGCGCAGGGCGTGCCGTAACATTCGGGATCTCGAGCGAGGCCGACATATCGGTCGAACACGGCTCGATCGCCGAAGGACC
GACGTCGATCGGCGCCACGGTGATCGACCGCAGGGACGCTTCGCGTCACCCGCTCACGCTCAAGATTCCGGGGCGCCACA
ACCTCGCCAATGCGCTTGCGGCCGTAGCGGCCGCCAATGCCGCCGGGCTTTCGGTCGCGGAAGCGGTCGCATCGCTGGTC
GGGTTCGAGGGCCTTGCCCGCCGTTTCGACATCGTCGGCACCAGCGCATCGGGCGTGACGGTGATCGACGATTTCGGTCA
CAATCCCGAAAAGGTCGGCGCCACGCTATCCACGCTGAAGGCCCATCCCGGGCGCGTCATCGCGTTTTTCCAGCCGCACG
GCTACGGCCCGCTGCGCCAGATGGGCGCGGAACTGGCAGAAGTCATGGCGCGAACCCTGGACGCCAACGACATTTCCGTC
CTTTGCGACCCGGTCTATTTCGGTGGCACTGTGGATCGCTCGGTCGGATCGGAACGCATTGTCGACTTGATCCGCTCCCA
CGGCGGCAAGGCGGAGTACATTGCCGAGCGGACGGATTGCGCCACGCGGATCGCCCAGCTTGCCAGACCGGGCGACCGTG
TCGTGATAATGGGCGCGCGCGACGACACCCTTTCCGCTTTTGCCCGGGACCTCCTGCAAGCGCTCTAG

Upstream 100 bases:

>100_bases
ATGCGTCTGGTCACCACGTCTCCCTAGACCGGTTCGCCCCTGCGACGGAAGCCGCAATCCCGAGGTTGTCACCGGGCGCG
CGGGCGCATACCGGAATGGC

Downstream 100 bases:

>100_bases
GGGGCGGCGCGCCGGACGCTCAGTCGAAGCGCTTTTCCAGCATCACCAGATGCGGATCTCCATCGATCCCGTGCGCCTCG
AAGCCCTTCTCGCGCTCCAG

Product: UDP-N-acetylmuramate--L-alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MTNTALPTPSSLADHDWFFCGIGGSGMLPLALILRGKGARVAGSDRSRDQGRTPEKFAWLEACGFSLFPQDGTGISSPDQ
ILVASAAVEDTVPEVVRARELGCARMSRAELLSALFNTAPVGVAVGGTSGKSTVTGMTGWILTYAGRDPTIMNGAVMKNF
VAPDAPFASARVGKGEAFVSEVDESDGSIALYNPAIAVLNNVSLDHKSLEELRELFGDFLARADTAVVNADDPESLALIG
RAGRAVTFGISSEADISVEHGSIAEGPTSIGATVIDRRDASRHPLTLKIPGRHNLANALAAVAAANAAGLSVAEAVASLV
GFEGLARRFDIVGTSASGVTVIDDFGHNPEKVGATLSTLKAHPGRVIAFFQPHGYGPLRQMGAELAEVMARTLDANDISV
LCDPVYFGGTVDRSVGSERIVDLIRSHGGKAEYIAERTDCATRIAQLARPGDRVVIMGARDDTLSAFARDLLQAL

Sequences:

>Translated_475_residues
MTNTALPTPSSLADHDWFFCGIGGSGMLPLALILRGKGARVAGSDRSRDQGRTPEKFAWLEACGFSLFPQDGTGISSPDQ
ILVASAAVEDTVPEVVRARELGCARMSRAELLSALFNTAPVGVAVGGTSGKSTVTGMTGWILTYAGRDPTIMNGAVMKNF
VAPDAPFASARVGKGEAFVSEVDESDGSIALYNPAIAVLNNVSLDHKSLEELRELFGDFLARADTAVVNADDPESLALIG
RAGRAVTFGISSEADISVEHGSIAEGPTSIGATVIDRRDASRHPLTLKIPGRHNLANALAAVAAANAAGLSVAEAVASLV
GFEGLARRFDIVGTSASGVTVIDDFGHNPEKVGATLSTLKAHPGRVIAFFQPHGYGPLRQMGAELAEVMARTLDANDISV
LCDPVYFGGTVDRSVGSERIVDLIRSHGGKAEYIAERTDCATRIAQLARPGDRVVIMGARDDTLSAFARDLLQAL
>Mature_474_residues
TNTALPTPSSLADHDWFFCGIGGSGMLPLALILRGKGARVAGSDRSRDQGRTPEKFAWLEACGFSLFPQDGTGISSPDQI
LVASAAVEDTVPEVVRARELGCARMSRAELLSALFNTAPVGVAVGGTSGKSTVTGMTGWILTYAGRDPTIMNGAVMKNFV
APDAPFASARVGKGEAFVSEVDESDGSIALYNPAIAVLNNVSLDHKSLEELRELFGDFLARADTAVVNADDPESLALIGR
AGRAVTFGISSEADISVEHGSIAEGPTSIGATVIDRRDASRHPLTLKIPGRHNLANALAAVAAANAAGLSVAEAVASLVG
FEGLARRFDIVGTSASGVTVIDDFGHNPEKVGATLSTLKAHPGRVIAFFQPHGYGPLRQMGAELAEVMARTLDANDISVL
CDPVYFGGTVDRSVGSERIVDLIRSHGGKAEYIAERTDCATRIAQLARPGDRVVIMGARDDTLSAFARDLLQAL

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1786279, Length=319, Percent_Identity=35.423197492163, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1790680, Length=456, Percent_Identity=27.1929824561404, Blast_Score=115, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 49612; Mature: 49480

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTALPTPSSLADHDWFFCGIGGSGMLPLALILRGKGARVAGSDRSRDQGRTPEKFAWL
CCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCEECCCCCCCCCCCCHHHHHHH
EACGFSLFPQDGTGISSPDQILVASAAVEDTVPEVVRARELGCARMSRAELLSALFNTAP
HHCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VGVAVGGTSGKSTVTGMTGWILTYAGRDPTIMNGAVMKNFVAPDAPFASARVGKGEAFVS
CEEEECCCCCCCEECCCCEEEEEECCCCCCEECHHHHHHHCCCCCCCCCCCCCCCHHHHH
EVDESDGSIALYNPAIAVLNNVSLDHKSLEELRELFGDFLARADTAVVNADDPESLALIG
HHCCCCCCEEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEE
RAGRAVTFGISSEADISVEHGSIAEGPTSIGATVIDRRDASRHPLTLKIPGRHNLANALA
CCCCEEEEECCCCCCEEECCCCCCCCCCCCCCCEEECCCCCCCCEEEEECCCCCHHHHHH
AVAAANAAGLSVAEAVASLVGFEGLARRFDIVGTSASGVTVIDDFGHNPEKVGATLSTLK
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCCHHHHHHHHHHHH
AHPGRVIAFFQPHGYGPLRQMGAELAEVMARTLDANDISVLCDPVYFGGTVDRSVGSERI
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCEEECCCCCCCCCHHHH
VDLIRSHGGKAEYIAERTDCATRIAQLARPGDRVVIMGARDDTLSAFARDLLQAL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHC
>Mature Secondary Structure 
TNTALPTPSSLADHDWFFCGIGGSGMLPLALILRGKGARVAGSDRSRDQGRTPEKFAWL
CCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCEECCCCCCCCCCCCHHHHHHH
EACGFSLFPQDGTGISSPDQILVASAAVEDTVPEVVRARELGCARMSRAELLSALFNTAP
HHCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VGVAVGGTSGKSTVTGMTGWILTYAGRDPTIMNGAVMKNFVAPDAPFASARVGKGEAFVS
CEEEECCCCCCCEECCCCEEEEEECCCCCCEECHHHHHHHCCCCCCCCCCCCCCCHHHHH
EVDESDGSIALYNPAIAVLNNVSLDHKSLEELRELFGDFLARADTAVVNADDPESLALIG
HHCCCCCCEEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEE
RAGRAVTFGISSEADISVEHGSIAEGPTSIGATVIDRRDASRHPLTLKIPGRHNLANALA
CCCCEEEEECCCCCCEEECCCCCCCCCCCCCCCEEECCCCCCCCEEEEECCCCCHHHHHH
AVAAANAAGLSVAEAVASLVGFEGLARRFDIVGTSASGVTVIDDFGHNPEKVGATLSTLK
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCCHHHHHHHHHHHH
AHPGRVIAFFQPHGYGPLRQMGAELAEVMARTLDANDISVLCDPVYFGGTVDRSVGSERI
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCEEECCCCCCCCCHHHH
VDLIRSHGGKAEYIAERTDCATRIAQLARPGDRVVIMGARDDTLSAFARDLLQAL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA