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The map label for this gene is purQ

Identifier: 87199054

GI number: 87199054

Start: 1071489

End: 1072166

Strand: Reverse

Name: purQ

Synonym: Saro_1032

Alternate gene names: 87199054

Gene position: 1072166-1071489 (Counterclockwise)

Preceding gene: 87199055

Following gene: 87199050

Centisome position: 30.1

GC content: 67.99

Gene sequence:

>678_bases
ATGGCCTTCACTTCCGCCGTCATCACCTTCCCGGGCTCCAACTGCGATCGCGACATGGCGGTGGCGATCGAACAGGTCTG
CGGCGGCACGGTCCACCGCGTCTGGCACGGCGATGCCGACCTGCCCGAAGGCCTTGATTTCATCGCACTGCCCGGCGGGT
TCTCCTATGGCGACTACCTGCGCTCCGGCGCAATGGCGGCCCGTTCGCCGGTCATGCAGGCCGTCGTCCGCGCGGCCGAG
CGCGGGGTGACGGTGCTCGGCGTCTGCAACGGCTTCCAGGTGCTGACCGAAGCCGGGCTTCTTCCCGGCGCGCTGATGCG
CAACGCGGGCATCCGCTTTGTCTGCCGCGACGTGAAGCTGACGGTCGAGAACAACCAGTCGCTGTTCACCGCCGGCTACG
ACGCGGGCCAGCAGATCACGATCCCCGTCGCGCACCACGACGGCAACTACTTCGCCGATGACGCGACGCTCGACCGTATC
GAAGGCGAAGGCCGCGTCGCGTTCCGCTATGCCGAAGAGGTCAACGGTTCGGCCCGCAACATCGCCGGCGTCCTCAACGA
CCGTGGCAACGTGCTGGGCATGATGCCGCACCCGGAACGCATGATCGAAGCCGCGCACGGCGGCAGCGACGGGCGCGCGC
TGTTCGAAAGCGTCGTGCGGGGCCTGGTAGAGGCCTAA

Upstream 100 bases:

>100_bases
CTTCGGACGAAGCGCTCGACGAGATGTGCCGCAAGCTCCTCGCCAACATGGTGATCGAGAACTACCGCATCGAAAAGGCG
GCCTGAAAAGGAACTTCCCC

Downstream 100 bases:

>100_bases
CCCGCCTTCCGCTCGAGGATGCGGGTCTGGCTGAACAGGCCGCGCGCATCCGCCGCGCTCATCGGGCGACCGAAGTAGTA
GCCCTGGATCTTCTTGCAGC

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MAFTSAVITFPGSNCDRDMAVAIEQVCGGTVHRVWHGDADLPEGLDFIALPGGFSYGDYLRSGAMAARSPVMQAVVRAAE
RGVTVLGVCNGFQVLTEAGLLPGALMRNAGIRFVCRDVKLTVENNQSLFTAGYDAGQQITIPVAHHDGNYFADDATLDRI
EGEGRVAFRYAEEVNGSARNIAGVLNDRGNVLGMMPHPERMIEAAHGGSDGRALFESVVRGLVEA

Sequences:

>Translated_225_residues
MAFTSAVITFPGSNCDRDMAVAIEQVCGGTVHRVWHGDADLPEGLDFIALPGGFSYGDYLRSGAMAARSPVMQAVVRAAE
RGVTVLGVCNGFQVLTEAGLLPGALMRNAGIRFVCRDVKLTVENNQSLFTAGYDAGQQITIPVAHHDGNYFADDATLDRI
EGEGRVAFRYAEEVNGSARNIAGVLNDRGNVLGMMPHPERMIEAAHGGSDGRALFESVVRGLVEA
>Mature_224_residues
AFTSAVITFPGSNCDRDMAVAIEQVCGGTVHRVWHGDADLPEGLDFIALPGGFSYGDYLRSGAMAARSPVMQAVVRAAER
GVTVLGVCNGFQVLTEAGLLPGALMRNAGIRFVCRDVKLTVENNQSLFTAGYDAGQQITIPVAHHDGNYFADDATLDRIE
GEGRVAFRYAEEVNGSARNIAGVLNDRGNVLGMMPHPERMIEAAHGGSDGRALFESVVRGLVEA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Escherichia coli, GI48994899, Length=183, Percent_Identity=36.6120218579235, Blast_Score=77, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6321498, Length=234, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24582111, Length=228, Percent_Identity=30.2631578947368, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24582109, Length=228, Percent_Identity=30.2631578947368, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17137292, Length=228, Percent_Identity=30.2631578947368, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURQ_NOVAD (Q2G9J6)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_496311.1
- ProteinModelPortal:   Q2G9J6
- SMR:   Q2G9J6
- STRING:   Q2G9J6
- GeneID:   3915814
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_1032
- NMPDR:   fig|48935.1.peg.1012
- eggNOG:   COG0047
- HOGENOM:   HBG302712
- OMA:   HPENHVE
- BioCyc:   NARO279238:SARO_1032-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00421
- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075
- PIRSF:   PIRSF001586
- TIGRFAMs:   TIGR01737

Pfam domain/function: PF07685 GATase_3

EC number: =6.3.5.3

Molecular weight: Translated: 23927; Mature: 23796

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS51273 GATASE_TYPE_1

Important sites: ACT_SITE 89-89 ACT_SITE 197-197 ACT_SITE 199-199

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFTSAVITFPGSNCDRDMAVAIEQVCGGTVHRVWHGDADLPEGLDFIALPGGFSYGDYL
CCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEECCCCCHHHHH
RSGAMAARSPVMQAVVRAAERGVTVLGVCNGFQVLTEAGLLPGALMRNAGIRFVCRDVKL
HHCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCCHHHHHCCCCEEEEEEEEE
TVENNQSLFTAGYDAGQQITIPVAHHDGNYFADDATLDRIEGEGRVAFRYAEEVNGSARN
EEECCCEEEEECCCCCCEEEEEEEECCCCEEECCCHHHHCCCCCEEEEEEHHHCCCCHHH
IAGVLNDRGNVLGMMPHPERMIEAAHGGSDGRALFESVVRGLVEA
HHHHCCCCCCEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AFTSAVITFPGSNCDRDMAVAIEQVCGGTVHRVWHGDADLPEGLDFIALPGGFSYGDYL
CCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEECCCCCHHHHH
RSGAMAARSPVMQAVVRAAERGVTVLGVCNGFQVLTEAGLLPGALMRNAGIRFVCRDVKL
HHCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCCHHHHHCCCCEEEEEEEEE
TVENNQSLFTAGYDAGQQITIPVAHHDGNYFADDATLDRIEGEGRVAFRYAEEVNGSARN
EEECCCEEEEECCCCCCEEEEEEEECCCCEEECCCHHHHCCCCCEEEEEEHHHCCCCHHH
IAGVLNDRGNVLGMMPHPERMIEAAHGGSDGRALFESVVRGLVEA
HHHHCCCCCCEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA