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The map label for this gene is lldD [H]

Identifier: 87198797

GI number: 87198797

Start: 822519

End: 823604

Strand: Reverse

Name: lldD [H]

Synonym: Saro_0774

Alternate gene names: 87198797

Gene position: 823604-822519 (Counterclockwise)

Preceding gene: 87198798

Following gene: 87198795

Centisome position: 23.12

GC content: 64.18

Gene sequence:

>1086_bases
ATGGCAGAGACGGTTTTCGAGCAGGTGACAGGCGAACAGGACCTGCTGGATGTTGGCGAGTTTCGCGCCGCGGCCGAGCC
GATGATGCCCGATCCCTACCGCAACTTCGTCAACAATGTCGGCATGGAGCGCACCCTGCACGACGACATCGCGGCTTGGC
AAGCGATGCACCTGCGGCCGCGTGCGCTGGTTGACGTCTCGCACATCGATACCTCGGCCACGGTGCTAGGGCAGCAGATC
GCGATGCCGATCATGACTGCGCCGTTTGTCGGCTCGACGCTGGTCGATCCCGAAGGCGAGGTGGCGACCGCGCGCGGCGC
AGTGGCGGCAGGCACGATCACCACGCTCAGCATGATGGGCACACGCCCACCCGAGGCCGTGGGGGCAGTTGCGAGCGGGC
GCTACTGGCAGCAGATTTACTTCATGCGCGATCGCGGCGTGGTAAAGGACGTGATTGAGCGGGCCGTAGCTGCAGGGGCT
TCGGCTTTATGTTTCACCGTAGATCTTCCGGTGATGCCGGCATTCCCCCGGCCCATGCGCCTTGCCGCGCAAGCGCTGTT
CCAGCGGTGGCAGGAACCGGAGCACGTGATGTATGCCGTCCGCGACTACGCGGACCGGCCGATGGGTGCAACCTTCCCCG
ATGCCGCCGCGACATGGGCCGACGTGGAATGGATGCGCACTCTTTCCAACCTCCCTCTAATCCTGAAAGGCGTGATCCGC
ACCGATGATGCCGCCCGCGCCCGCGATCATGGCGCGAGCGCCTTGATCGTATCCAATCACGCTGGCCAGGGTCTTCGCCA
TTCACAACCGGTCGCGCACGCCCTACCGGCAATCGTTGAGGCCGTTGGGCGCGACATTGAAGTCTATGCAGACAGCGGCA
TTCGTACAGGTGCCGACGTTCTGCGGGCTTTGGCACTTGGCGCACGTGCCGTTCTGGTCGGCCGCCCAGTGCTTTGGGGC
TTGACCACGGGGGGCTCTCAGGGAGTCGAGCGTGTGCTGAAGTTGCTGCAGGCCGAACTCGCCGAAATCATGGCAATCAC
CGGAGCCTCGAGCATTGGTGCGATCGATGGGTCGGTTTTGGCGTAG

Upstream 100 bases:

>100_bases
GGGCGGAGACCTACTTCCGTGCGATCACGATCGAGCCGATCCGCCGCCTACCGACCATCACCGAGCGAAAGCCGGGCTGA
TCCCAAAGGAGCAGACAATC

Downstream 100 bases:

>100_bases
GCGGGCTCGTTTGACACCTAGTGGCGGCCACACCCTGAAACGGACCTGTCCGATCGGCCCTATCTTGCGCTGGCCGAGGT
GACCGCAGCCAAGCGGATGA

Product: FMN-dependent alpha-hydroxy acid dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MAETVFEQVTGEQDLLDVGEFRAAAEPMMPDPYRNFVNNVGMERTLHDDIAAWQAMHLRPRALVDVSHIDTSATVLGQQI
AMPIMTAPFVGSTLVDPEGEVATARGAVAAGTITTLSMMGTRPPEAVGAVASGRYWQQIYFMRDRGVVKDVIERAVAAGA
SALCFTVDLPVMPAFPRPMRLAAQALFQRWQEPEHVMYAVRDYADRPMGATFPDAAATWADVEWMRTLSNLPLILKGVIR
TDDAARARDHGASALIVSNHAGQGLRHSQPVAHALPAIVEAVGRDIEVYADSGIRTGADVLRALALGARAVLVGRPVLWG
LTTGGSQGVERVLKLLQAELAEIMAITGASSIGAIDGSVLA

Sequences:

>Translated_361_residues
MAETVFEQVTGEQDLLDVGEFRAAAEPMMPDPYRNFVNNVGMERTLHDDIAAWQAMHLRPRALVDVSHIDTSATVLGQQI
AMPIMTAPFVGSTLVDPEGEVATARGAVAAGTITTLSMMGTRPPEAVGAVASGRYWQQIYFMRDRGVVKDVIERAVAAGA
SALCFTVDLPVMPAFPRPMRLAAQALFQRWQEPEHVMYAVRDYADRPMGATFPDAAATWADVEWMRTLSNLPLILKGVIR
TDDAARARDHGASALIVSNHAGQGLRHSQPVAHALPAIVEAVGRDIEVYADSGIRTGADVLRALALGARAVLVGRPVLWG
LTTGGSQGVERVLKLLQAELAEIMAITGASSIGAIDGSVLA
>Mature_360_residues
AETVFEQVTGEQDLLDVGEFRAAAEPMMPDPYRNFVNNVGMERTLHDDIAAWQAMHLRPRALVDVSHIDTSATVLGQQIA
MPIMTAPFVGSTLVDPEGEVATARGAVAAGTITTLSMMGTRPPEAVGAVASGRYWQQIYFMRDRGVVKDVIERAVAAGAS
ALCFTVDLPVMPAFPRPMRLAAQALFQRWQEPEHVMYAVRDYADRPMGATFPDAAATWADVEWMRTLSNLPLILKGVIRT
DDAARARDHGASALIVSNHAGQGLRHSQPVAHALPAIVEAVGRDIEVYADSGIRTGADVLRALALGARAVLVGRPVLWGL
TTGGSQGVERVLKLLQAELAEIMAITGASSIGAIDGSVLA

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI54234014, Length=350, Percent_Identity=36.5714285714286, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI7705393, Length=350, Percent_Identity=36.5714285714286, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI11068137, Length=359, Percent_Identity=34.5403899721448, Blast_Score=211, Evalue=1e-54,
Organism=Escherichia coli, GI1790033, Length=364, Percent_Identity=34.8901098901099, Blast_Score=193, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI193208036, Length=357, Percent_Identity=35.5742296918768, Blast_Score=210, Evalue=9e-55,
Organism=Caenorhabditis elegans, GI32566217, Length=270, Percent_Identity=31.4814814814815, Blast_Score=131, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6323587, Length=335, Percent_Identity=31.044776119403, Blast_Score=160, Evalue=3e-40,
Organism=Drosophila melanogaster, GI281363140, Length=341, Percent_Identity=34.6041055718475, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI78707190, Length=341, Percent_Identity=34.6041055718475, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI78707188, Length=341, Percent_Identity=34.6041055718475, Blast_Score=181, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 38583; Mature: 38452

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETVFEQVTGEQDLLDVGEFRAAAEPMMPDPYRNFVNNVGMERTLHDDIAAWQAMHLRP
CCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
RALVDVSHIDTSATVLGQQIAMPIMTAPFVGSTLVDPEGEVATARGAVAAGTITTLSMMG
HHEEEHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHC
TRPPEAVGAVASGRYWQQIYFMRDRGVVKDVIERAVAAGASALCFTVDLPVMPAFPRPMR
CCCHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHH
LAAQALFQRWQEPEHVMYAVRDYADRPMGATFPDAAATWADVEWMRTLSNLPLILKGVIR
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHC
TDDAARARDHGASALIVSNHAGQGLRHSQPVAHALPAIVEAVGRDIEVYADSGIRTGADV
CCCHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHH
LRALALGARAVLVGRPVLWGLTTGGSQGVERVLKLLQAELAEIMAITGASSIGAIDGSVL
HHHHHHCCHHEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
A
C
>Mature Secondary Structure 
AETVFEQVTGEQDLLDVGEFRAAAEPMMPDPYRNFVNNVGMERTLHDDIAAWQAMHLRP
CHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
RALVDVSHIDTSATVLGQQIAMPIMTAPFVGSTLVDPEGEVATARGAVAAGTITTLSMMG
HHEEEHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHC
TRPPEAVGAVASGRYWQQIYFMRDRGVVKDVIERAVAAGASALCFTVDLPVMPAFPRPMR
CCCHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHH
LAAQALFQRWQEPEHVMYAVRDYADRPMGATFPDAAATWADVEWMRTLSNLPLILKGVIR
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHC
TDDAARARDHGASALIVSNHAGQGLRHSQPVAHALPAIVEAVGRDIEVYADSGIRTGADV
CCCHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHH
LRALALGARAVLVGRPVLWGLTTGGSQGVERVLKLLQAELAEIMAITGASSIGAIDGSVL
HHHHHHCCHHEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA