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The map label for this gene is hpd [H]

Identifier: 87198621

GI number: 87198621

Start: 642174

End: 643286

Strand: Reverse

Name: hpd [H]

Synonym: Saro_0597

Alternate gene names: 87198621

Gene position: 643286-642174 (Counterclockwise)

Preceding gene: 87198628

Following gene: 87198619

Centisome position: 18.06

GC content: 65.41

Gene sequence:

>1113_bases
GTGAGCATCCAGACAAAGGGCCAGACCGACCTGTTCGAAAACCCGCTCGGCCTCGACGGCTTCGAATTCATCGAGTTCTC
CGCACCGGAAGCGGGCAGCCTCGAGCCAGTCTTCGCGCGCATGGGCTTCACCCACATCGCCAACCATCGCTCCAAGCAGG
TCCAGCTCTGGCGCCAGGGCGGCATCAACCTCATCGCCAACCACGAACCGCGCAGCCCTGCGGCCTACTTCGCCGCCGAG
CACGGCCCATCGGCCTGCGGCATGGGCTGGCGCGTGCGCAACGCGGCCAAGGCCTATGCCACCGCTATCGAGCGCGGGGC
CGAGCCGGTCGAGGTCCGCACCGGACCGATGGAACTGCGCCTGCCCGCGATCCGCGGCATCGGCGGTTCGATCATCTATC
TCATCGACCGCTACGAAGGCGGCCAGTTCGGCGACCTCTCGATCTACGACATCGACTTCGAATATCTCCCCGGAGTGGAC
CGGCATCCCGTCGGCGCGGGTTTCCACACCATCGACCACCTGACCCACAACGTCTACGGCGGGCGCATGGCGCACTGGGC
TTCGTTCTACGAGCGCGTGTTCGGCTTCCGCGAGATCCGCTACTTCGACATCAAGGGCGAATATACCGGCCTCACCAGCC
GAGCGATGACCGCGCCCGATGGCAAGATCCGCATTCCGCTGAACGAGGAAGCCAAGGCAGGCGGCGGCCAGATCGAGGAG
TTCCTGCGCGCCTACAACGGCGAGGGCATCCAGCACATCGCCTTCGCCTGCGACGACCTGCTCGGCGGGTGGGACAAGCT
CAAGGCCATTGGCACCCCCTTCATGTCCCCGCCGCCCGCGACCTACTACGAAATGCTCGACGAACGCCTGCCCGGCCATG
GCGAGCCGGTGGCGGAACTGCAGAAGCGCGGCATCCTGCTCGACGGCTCCACCGAAGAGGGCGATCCCCGCCTCCTGCTG
CAGATCTTCTCCGAAACCCAGATCGGCCCGGTGTTCTTCGAGTTCATCCAGCGCAAGCGCGACGAAGGCTTTGGCGAAGG
CAATTTCACCGCCCTGTTCAAGTCGATGGAACGCGACCAGCTTCGTCGCGGCGTGCTCAAGACCGAAGCCTGA

Upstream 100 bases:

>100_bases
ACCCGTAAATCCCTGCCCACTTTGCGCGGACCACGCAAGCCGCTTGTGGTATCATCCGCTCGATATCCCGCACGGCGGAC
GATCGCATGGAGAGTGACGC

Downstream 100 bases:

>100_bases
CCGCAAACCGGATCGCGGCGGCGCCCGGCCTCTACTTCTGGCACCTGGGGCAGAAGAAGGTCGAGCGCCCGCCCTGCACG
ATCCGCTTCACCACGCCCCC

Product: 4-hydroxyphenylpyruvate dioxygenase

Products: NA

Alternate protein names: 4HPPD; HPD; HPPDase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSIQTKGQTDLFENPLGLDGFEFIEFSAPEAGSLEPVFARMGFTHIANHRSKQVQLWRQGGINLIANHEPRSPAAYFAAE
HGPSACGMGWRVRNAAKAYATAIERGAEPVEVRTGPMELRLPAIRGIGGSIIYLIDRYEGGQFGDLSIYDIDFEYLPGVD
RHPVGAGFHTIDHLTHNVYGGRMAHWASFYERVFGFREIRYFDIKGEYTGLTSRAMTAPDGKIRIPLNEEAKAGGGQIEE
FLRAYNGEGIQHIAFACDDLLGGWDKLKAIGTPFMSPPPATYYEMLDERLPGHGEPVAELQKRGILLDGSTEEGDPRLLL
QIFSETQIGPVFFEFIQRKRDEGFGEGNFTALFKSMERDQLRRGVLKTEA

Sequences:

>Translated_370_residues
MSIQTKGQTDLFENPLGLDGFEFIEFSAPEAGSLEPVFARMGFTHIANHRSKQVQLWRQGGINLIANHEPRSPAAYFAAE
HGPSACGMGWRVRNAAKAYATAIERGAEPVEVRTGPMELRLPAIRGIGGSIIYLIDRYEGGQFGDLSIYDIDFEYLPGVD
RHPVGAGFHTIDHLTHNVYGGRMAHWASFYERVFGFREIRYFDIKGEYTGLTSRAMTAPDGKIRIPLNEEAKAGGGQIEE
FLRAYNGEGIQHIAFACDDLLGGWDKLKAIGTPFMSPPPATYYEMLDERLPGHGEPVAELQKRGILLDGSTEEGDPRLLL
QIFSETQIGPVFFEFIQRKRDEGFGEGNFTALFKSMERDQLRRGVLKTEA
>Mature_369_residues
SIQTKGQTDLFENPLGLDGFEFIEFSAPEAGSLEPVFARMGFTHIANHRSKQVQLWRQGGINLIANHEPRSPAAYFAAEH
GPSACGMGWRVRNAAKAYATAIERGAEPVEVRTGPMELRLPAIRGIGGSIIYLIDRYEGGQFGDLSIYDIDFEYLPGVDR
HPVGAGFHTIDHLTHNVYGGRMAHWASFYERVFGFREIRYFDIKGEYTGLTSRAMTAPDGKIRIPLNEEAKAGGGQIEEF
LRAYNGEGIQHIAFACDDLLGGWDKLKAIGTPFMSPPPATYYEMLDERLPGHGEPVAELQKRGILLDGSTEEGDPRLLLQ
IFSETQIGPVFFEFIQRKRDEGFGEGNFTALFKSMERDQLRRGVLKTEA

Specific function: Unknown

COG id: COG3185

COG function: function code ER; 4-hydroxyphenylpyruvate dioxygenase and related hemolysins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 4HPPD family [H]

Homologues:

Organism=Homo sapiens, GI285002264, Length=363, Percent_Identity=28.6501377410468, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI4504477, Length=363, Percent_Identity=28.6501377410468, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI14249394, Length=373, Percent_Identity=26.5415549597855, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17555220, Length=315, Percent_Identity=33.6507936507937, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17550752, Length=305, Percent_Identity=29.5081967213115, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21356105, Length=308, Percent_Identity=33.1168831168831, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24667510, Length=308, Percent_Identity=33.1168831168831, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005956
- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: =1.13.11.27 [H]

Molecular weight: Translated: 41224; Mature: 41093

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQTKGQTDLFENPLGLDGFEFIEFSAPEAGSLEPVFARMGFTHIANHRSKQVQLWRQG
CCCCCCCCCHHHCCCCCCCCCCEEEECCCCCCCCCHHHHHHCHHHHHHCCHHHHHHHHCC
GINLIANHEPRSPAAYFAAEHGPSACGMGWRVRNAAKAYATAIERGAEPVEVRTGPMELR
CCEEEECCCCCCCHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCEEEE
LPAIRGIGGSIIYLIDRYEGGQFGDLSIYDIDFEYLPGVDRHPVGAGFHTIDHLTHNVYG
EHHHHCCCCEEEEEEECCCCCCCCCEEEEEECHHHCCCCCCCCCCCCHHHHHHHHHHHCC
GRMAHWASFYERVFGFREIRYFDIKGEYTGLTSRAMTAPDGKIRIPLNEEAKAGGGQIEE
CHHHHHHHHHHHHHCHHHEEEEEECCCCCCCCCCCEECCCCEEEECCCCCCCCCCHHHHH
FLRAYNGEGIQHIAFACDDLLGGWDKLKAIGTPFMSPPPATYYEMLDERLPGHGEPVAEL
HHHHHCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHHH
QKRGILLDGSTEEGDPRLLLQIFSETQIGPVFFEFIQRKRDEGFGEGNFTALFKSMERDQ
HHCCEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
LRRGVLKTEA
HHHCHHCCCC
>Mature Secondary Structure 
SIQTKGQTDLFENPLGLDGFEFIEFSAPEAGSLEPVFARMGFTHIANHRSKQVQLWRQG
CCCCCCCCHHHCCCCCCCCCCEEEECCCCCCCCCHHHHHHCHHHHHHCCHHHHHHHHCC
GINLIANHEPRSPAAYFAAEHGPSACGMGWRVRNAAKAYATAIERGAEPVEVRTGPMELR
CCEEEECCCCCCCHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCEEEE
LPAIRGIGGSIIYLIDRYEGGQFGDLSIYDIDFEYLPGVDRHPVGAGFHTIDHLTHNVYG
EHHHHCCCCEEEEEEECCCCCCCCCEEEEEECHHHCCCCCCCCCCCCHHHHHHHHHHHCC
GRMAHWASFYERVFGFREIRYFDIKGEYTGLTSRAMTAPDGKIRIPLNEEAKAGGGQIEE
CHHHHHHHHHHHHHCHHHEEEEEECCCCCCCCCCCEECCCCEEEECCCCCCCCCCHHHHH
FLRAYNGEGIQHIAFACDDLLGGWDKLKAIGTPFMSPPPATYYEMLDERLPGHGEPVAEL
HHHHHCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHHH
QKRGILLDGSTEEGDPRLLLQIFSETQIGPVFFEFIQRKRDEGFGEGNFTALFKSMERDQ
HHCCEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
LRRGVLKTEA
HHHCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1572351; 10467142 [H]