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The map label for this gene is tadA [H]

Identifier: 87198248

GI number: 87198248

Start: 231976

End: 232431

Strand: Direct

Name: tadA [H]

Synonym: Saro_0223

Alternate gene names: 87198248

Gene position: 231976-232431 (Clockwise)

Preceding gene: 87198246

Following gene: 87198263

Centisome position: 6.51

GC content: 72.37

Gene sequence:

>456_bases
ATGACCCGCTGGCCCCTTCCCGAACCGATGCGATTGGCCCTGGACGAGGCCCTGCGCGCGGCGGATGAGGGCGAAGTGCC
CATCGGCGCGGTCGTCGTCAAGGACGGCAAGGTCGTCGCCGCGGCCCACAACCGCCCGCGCACCCTGCGCGACCCCACCG
CCCACGCAGAGATGCTGGCGATTCGCGCCGCCGCCGCGCAGCTCGGGCAGGAGCGACTGGAAGGGTGCGATCTGTGGGTC
AGCCTCGAACCCTGCGCGATGTGCGCGGGCGCCATCGCCCACGCCCGCATCGCGCGGGTCTACTACGCGGCAAGCGATCC
CAAGGGCGGCGCGGTGGAACACGGCAGCCGGGTCTTCGACCAGCCGACCTGCCTGCACCGCCCGGAGGTCTATTCCGGCA
TGGGCGAGGCCGAGGCGGCGGAAATGCTGCGCACCTTCTTCCGCGACCGGCGCTAG

Upstream 100 bases:

>100_bases
CGATAATACCTATCGGGAAGGCGCGGCTCTTATCGATTCACCACGCGAAGTCAAGGATTCGGAGTTTGAAAGCGACGTTC
CGGCACCTATACCCCGCGCG

Downstream 100 bases:

>100_bases
ACCGCCGGGCTCAGAACGAACGCCAGATCTTCACCGGCACCGTGTCGGCCGGCTTCGTGCCGCCGGGGCAGCGCGCAGGC
TTCATCCGGCGCGAAAGGCA

Product: tRNA-adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MTRWPLPEPMRLALDEALRAADEGEVPIGAVVVKDGKVVAAAHNRPRTLRDPTAHAEMLAIRAAAAQLGQERLEGCDLWV
SLEPCAMCAGAIAHARIARVYYAASDPKGGAVEHGSRVFDQPTCLHRPEVYSGMGEAEAAEMLRTFFRDRR

Sequences:

>Translated_151_residues
MTRWPLPEPMRLALDEALRAADEGEVPIGAVVVKDGKVVAAAHNRPRTLRDPTAHAEMLAIRAAAAQLGQERLEGCDLWV
SLEPCAMCAGAIAHARIARVYYAASDPKGGAVEHGSRVFDQPTCLHRPEVYSGMGEAEAAEMLRTFFRDRR
>Mature_150_residues
TRWPLPEPMRLALDEALRAADEGEVPIGAVVVKDGKVVAAAHNRPRTLRDPTAHAEMLAIRAAAAQLGQERLEGCDLWVS
LEPCAMCAGAIAHARIARVYYAASDPKGGAVEHGSRVFDQPTCLHRPEVYSGMGEAEAAEMLRTFFRDRR

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=152, Percent_Identity=31.5789473684211, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI145693172, Length=142, Percent_Identity=46.4788732394366, Blast_Score=120, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17554608, Length=113, Percent_Identity=40.7079646017699, Blast_Score=97, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17555996, Length=121, Percent_Identity=41.3223140495868, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17541138, Length=139, Percent_Identity=33.8129496402878, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=34.9315068493151, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16461; Mature: 16330

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRWPLPEPMRLALDEALRAADEGEVPIGAVVVKDGKVVAAAHNRPRTLRDPTAHAEMLA
CCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEECCCCCCCCCCCHHHHHHHH
IRAAAAQLGQERLEGCDLWVSLEPCAMCAGAIAHARIARVYYAASDPKGGAVEHGSRVFD
HHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHCC
QPTCLHRPEVYSGMGEAEAAEMLRTFFRDRR
CCCCCCCCHHHCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRWPLPEPMRLALDEALRAADEGEVPIGAVVVKDGKVVAAAHNRPRTLRDPTAHAEMLA
CCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEECCCCCCCCCCCHHHHHHHH
IRAAAAQLGQERLEGCDLWVSLEPCAMCAGAIAHARIARVYYAASDPKGGAVEHGSRVFD
HHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHCC
QPTCLHRPEVYSGMGEAEAAEMLRTFFRDRR
CCCCCCCCHHHCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]