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The map label for this gene is msrB [H]

Identifier: 87198246

GI number: 87198246

Start: 230975

End: 231466

Strand: Direct

Name: msrB [H]

Synonym: Saro_0221

Alternate gene names: 87198246

Gene position: 230975-231466 (Clockwise)

Preceding gene: 87198245

Following gene: 87198248

Centisome position: 6.49

GC content: 69.31

Gene sequence:

>492_bases
ATGATGCCAGACGCCGACCGCCGCCGTTTCCTCGCCCTGCTGGGCGCGGGCGCGGTCATGCCGCTCGCCAGCGCCTGCAG
CGCCAGGCCGGCGGCCAAAGGTACGTTTCCGATCATGCACAGCGATGCCGAGTGGCGTCGCCTGCTCACGCCCGAGCAAT
ACTACATCCTGCGCGAGGCGGGCACCGAACGGCCCTTCACCTCGCCCCTGCTCAAGGAAAAGCGCAAGGGCGCGTTCGTC
TGCGCGGCGGACGGAAACGCGCTGTTCGCCTCGGGCACCAAGTTCGAGAGTGGTACCGGCTGGCCCAGCTTCTGGCGTCC
GCTGCCCAGGGCCGTCGGCACCAGCAGCGACCGGACGCTCGGCATGGTGCGCACCGAGGTGCATTGCAGCCAGTGCGGCG
GCCATCTCGGACATGTGTTCGACGACGGTCCGCCGCCCACGGGCCTGCGCTACTGCATCAATGGCGATGCGCTGAAGTTC
CGGCCCGCCTGA

Upstream 100 bases:

>100_bases
GGCAGGTTGGTCTAGGCAGGGACAAGTCCTGCCGGTTGGCCAGCCGCCGCTCTAGGTACTCGCCCTCCCCGGCCCGTCGG
CAGGACACCGAGGTAGCCAG

Downstream 100 bases:

>100_bases
CACGGCGCAGGCGCAGCAACGACCGAATCACCGGAAACGCCAAAGACCCCCATTCCATGCGGAAAGGGGGTCCAGGTCTT
CGATCCCTTGCGGGAGAAGT

Product: protein-methionine-S-oxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MMPDADRRRFLALLGAGAVMPLASACSARPAAKGTFPIMHSDAEWRRLLTPEQYYILREAGTERPFTSPLLKEKRKGAFV
CAADGNALFASGTKFESGTGWPSFWRPLPRAVGTSSDRTLGMVRTEVHCSQCGGHLGHVFDDGPPPTGLRYCINGDALKF
RPA

Sequences:

>Translated_163_residues
MMPDADRRRFLALLGAGAVMPLASACSARPAAKGTFPIMHSDAEWRRLLTPEQYYILREAGTERPFTSPLLKEKRKGAFV
CAADGNALFASGTKFESGTGWPSFWRPLPRAVGTSSDRTLGMVRTEVHCSQCGGHLGHVFDDGPPPTGLRYCINGDALKF
RPA
>Mature_163_residues
MMPDADRRRFLALLGAGAVMPLASACSARPAAKGTFPIMHSDAEWRRLLTPEQYYILREAGTERPFTSPLLKEKRKGAFV
CAADGNALFASGTKFESGTGWPSFWRPLPRAVGTSSDRTLGMVRTEVHCSQCGGHLGHVFDDGPPPTGLRYCINGDALKF
RPA

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=132, Percent_Identity=48.4848484848485, Blast_Score=130, Evalue=4e-31,
Organism=Homo sapiens, GI301336162, Length=132, Percent_Identity=48.4848484848485, Blast_Score=130, Evalue=4e-31,
Organism=Homo sapiens, GI73089054, Length=132, Percent_Identity=48.4848484848485, Blast_Score=130, Evalue=4e-31,
Organism=Homo sapiens, GI37620216, Length=141, Percent_Identity=47.5177304964539, Blast_Score=130, Evalue=6e-31,
Organism=Homo sapiens, GI117606353, Length=134, Percent_Identity=48.5074626865672, Blast_Score=124, Evalue=4e-29,
Organism=Escherichia coli, GI1788077, Length=121, Percent_Identity=45.4545454545455, Blast_Score=116, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI115532676, Length=122, Percent_Identity=44.2622950819672, Blast_Score=103, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17553450, Length=122, Percent_Identity=44.2622950819672, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6319816, Length=128, Percent_Identity=35.9375, Blast_Score=91, Evalue=6e-20,
Organism=Drosophila melanogaster, GI221378662, Length=126, Percent_Identity=47.6190476190476, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI221378664, Length=119, Percent_Identity=50.4201680672269, Blast_Score=123, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24645799, Length=119, Percent_Identity=47.0588235294118, Blast_Score=115, Evalue=9e-27,
Organism=Drosophila melanogaster, GI45553335, Length=119, Percent_Identity=47.0588235294118, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21356369, Length=119, Percent_Identity=47.0588235294118, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24645801, Length=130, Percent_Identity=43.0769230769231, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24645804, Length=130, Percent_Identity=43.0769230769231, Blast_Score=111, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 17726; Mature: 17726

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPDADRRRFLALLGAGAVMPLASACSARPAAKGTFPIMHSDAEWRRLLTPEQYYILREA
CCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHCCCCCEEEEECC
GTERPFTSPLLKEKRKGAFVCAADGNALFASGTKFESGTGWPSFWRPLPRAVGTSSDRTL
CCCCCCCCHHHHHHCCCCEEEEECCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEE
GMVRTEVHCSQCGGHLGHVFDDGPPPTGLRYCINGDALKFRPA
EEHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEEECC
>Mature Secondary Structure
MMPDADRRRFLALLGAGAVMPLASACSARPAAKGTFPIMHSDAEWRRLLTPEQYYILREA
CCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHCCCCCEEEEECC
GTERPFTSPLLKEKRKGAFVCAADGNALFASGTKFESGTGWPSFWRPLPRAVGTSSDRTL
CCCCCCCCHHHHHHCCCCEEEEECCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEE
GMVRTEVHCSQCGGHLGHVFDDGPPPTGLRYCINGDALKFRPA
EEHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]