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The map label for this gene is yesM [H]

Identifier: 87198215

GI number: 87198215

Start: 193439

End: 195367

Strand: Direct

Name: yesM [H]

Synonym: Saro_0189

Alternate gene names: 87198215

Gene position: 193439-195367 (Clockwise)

Preceding gene: 87198214

Following gene: 87198216

Centisome position: 5.43

GC content: 68.12

Gene sequence:

>1929_bases
ATGACGTTGTCGCAAATCGATCCGGGCGTCCCGCGCGTGCCGGCACGGCAGGTAATCCTGTCGGCCGTGGCGCTGTGGCT
CTGCTACTTCGTGCTGATTACCGTGCGCGGGCTGGTGGTCGAACTGGGCGACTTTTCGGACCTCCTGTGGCGGCGTGCGC
TGGTGACCGTTGCAGGGATCGTCGTGACCGTAGCCTGCTGGCCGTTGCTGCGCCGCTTCGATGCGCGCCCGCTGGCAACG
CGCGTGGGGGCGGCCCTGGTCATCATGCTTCCGGCCGCGCTTGCGCTGGCGGCAGTCAACCAATGGGCCTTCGCCCCGGT
CGAAAAGCGGATGATCGAGCGGATCAGCACCGATCAGGGCGATGAAGCCCCGACCCGCACCTCGCAGGTCACCGTGAAGA
ACGGCGATGGCAAGGGCGGCGCGGTCAAGATCCGCCACGACATGGCCGGCAACGTTCTGGTCGACGTGCTGGACGAGGGC
TTCGTTCCGCCCGTACCTGCTCCACCCCCTGCCCCGCCGCCGGCACCCCGCACCCCGCACCCCACCCATGCCCCGGGCTC
GACGGCCCACGCCTCGCCGACGACGGAACCGTTGCTCAGCGAGGAGGACGTTGCGGAACTGCGCAACCTGGGCGACGAAC
GCACCATAGAGGCCTTGAAGAACGCCGGGATCGTGCAGAATCCCGACGGCAGCACGGTGATCTCCCAGCCGGGGCTCTAT
GTGCGGCAATATGCCGATGGCCGCTCCGAAGTGCGCACTGGCGGCAAGGTCTATGTCGTGGGCGATGACGGCGAGGTTGA
ATCGATCCTGAGCGGCGCCCGGGACCCGGTCCCGCCGGAACCTCCTGCCCCCGCTGCCAGCGCGGTTCCTCCAGCACCCC
CGGCACCACCGGCCCCGGCAATTTCTGCCGCCATGCAGGAGAAGGTGCGCGAAGCCGCGCGGCGCGAGACCGAGAAGGCG
CTGGGCAAGGCCGACGCGCTGCGCAAGGCCGCGCTGGCCCGCGCGCGCGAAGCCCGTGCCCGACATGCCGACGCGCATCC
CGTGGCCCAGCCTTCCGTCTCGGCCCGGCCTGCCGTTTCGGCCGAGCCCGCCGCTTCCGCCACGCCCGAACCATCGCCCT
CGGAGATCGTCACCGAGGATTATCGCGGCTCCGACCATGTGACGATCATCCGCCAGACGGTAGAGAACGAGGGGCTGTGG
CGGCAACTCACCGACGTTGCCCTTGGTCGCTACTTCCTGCTCATCGCCTGGGCCGCGCTCTATCTTGCGCTGGGCAATGG
CGAGCAACTCCGCGCCGCCGAATATCGCGAGGGCGAATACCGGCGTGCGGCCAAGGCATCGGAATTGCGCTCGCTGCGCT
ACCAGGTGAACCCGCACTTCCTGTTCAACACGCTCAATTCGCTGTCGGCCCTGGTCATGGTCGGTCGCAGCGAACAGGCC
GAGCGAATGATCCAGTCGATCTCGCGCTTCTACCGTCACAGCCTTGCCGGCGATCCCACTGCGGACGTCCCGCTGGAGGA
CGAGATCGCGCTCCAGCGCCACTACCTCGACATCGAGGCGGTGCGCTTCCCTGACAGGCTGCGGTGCGAGTTCGATGTTC
CGGACGATCTGATGACGGCCTGCGTGCCGGGCATGATCCTGCAGCCGTTGGTTGAGAACTCGATCAAGTACGCGGTCTCG
ACCACTATCCGCCCGGTGACGATCCGCATAGCCGCGCGCGAGGCGGGCGGTTTCCTGATCCTGACGGTGGCAGACGACGG
GCCGGGCGAAAGCTTCGTCAACGGCGGCACCGGCATCGGCCTTGCCAACGTGAAGAGCCGCCTCGCCGCGCGCTTTGGCG
AGGACGCGGCCAAGGTGGAAAGCGGGCCGCTGCCGGCGGGCGGCTATGCGACCGTGCTGACGCTGCCGATTGTCCGCAAC
GAATGCTGA

Upstream 100 bases:

>100_bases
CCTTCCGGCCTGACCTTCCTTTCTTTCGCTTCGATGAACCGCATATCCCGCCCGACCACCGTTCTGGTGCGTCGGGCGGT
TCGCGTTTAGGCTGAACGCC

Downstream 100 bases:

>100_bases
GGGGGAAGAATTGCGCACGTTGATAGTCGACGACGAACCGCTGGCGGTGGAGCGCATGCAGATCCTCTGCGCGCGCATCC
CCGCGCTCCAGGTGGTGGGG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 642; Mature: 641

Protein sequence:

>642_residues
MTLSQIDPGVPRVPARQVILSAVALWLCYFVLITVRGLVVELGDFSDLLWRRALVTVAGIVVTVACWPLLRRFDARPLAT
RVGAALVIMLPAALALAAVNQWAFAPVEKRMIERISTDQGDEAPTRTSQVTVKNGDGKGGAVKIRHDMAGNVLVDVLDEG
FVPPVPAPPPAPPPAPRTPHPTHAPGSTAHASPTTEPLLSEEDVAELRNLGDERTIEALKNAGIVQNPDGSTVISQPGLY
VRQYADGRSEVRTGGKVYVVGDDGEVESILSGARDPVPPEPPAPAASAVPPAPPAPPAPAISAAMQEKVREAARRETEKA
LGKADALRKAALARAREARARHADAHPVAQPSVSARPAVSAEPAASATPEPSPSEIVTEDYRGSDHVTIIRQTVENEGLW
RQLTDVALGRYFLLIAWAALYLALGNGEQLRAAEYREGEYRRAAKASELRSLRYQVNPHFLFNTLNSLSALVMVGRSEQA
ERMIQSISRFYRHSLAGDPTADVPLEDEIALQRHYLDIEAVRFPDRLRCEFDVPDDLMTACVPGMILQPLVENSIKYAVS
TTIRPVTIRIAAREAGGFLILTVADDGPGESFVNGGTGIGLANVKSRLAARFGEDAAKVESGPLPAGGYATVLTLPIVRN
EC

Sequences:

>Translated_642_residues
MTLSQIDPGVPRVPARQVILSAVALWLCYFVLITVRGLVVELGDFSDLLWRRALVTVAGIVVTVACWPLLRRFDARPLAT
RVGAALVIMLPAALALAAVNQWAFAPVEKRMIERISTDQGDEAPTRTSQVTVKNGDGKGGAVKIRHDMAGNVLVDVLDEG
FVPPVPAPPPAPPPAPRTPHPTHAPGSTAHASPTTEPLLSEEDVAELRNLGDERTIEALKNAGIVQNPDGSTVISQPGLY
VRQYADGRSEVRTGGKVYVVGDDGEVESILSGARDPVPPEPPAPAASAVPPAPPAPPAPAISAAMQEKVREAARRETEKA
LGKADALRKAALARAREARARHADAHPVAQPSVSARPAVSAEPAASATPEPSPSEIVTEDYRGSDHVTIIRQTVENEGLW
RQLTDVALGRYFLLIAWAALYLALGNGEQLRAAEYREGEYRRAAKASELRSLRYQVNPHFLFNTLNSLSALVMVGRSEQA
ERMIQSISRFYRHSLAGDPTADVPLEDEIALQRHYLDIEAVRFPDRLRCEFDVPDDLMTACVPGMILQPLVENSIKYAVS
TTIRPVTIRIAAREAGGFLILTVADDGPGESFVNGGTGIGLANVKSRLAARFGEDAAKVESGPLPAGGYATVLTLPIVRN
EC
>Mature_641_residues
TLSQIDPGVPRVPARQVILSAVALWLCYFVLITVRGLVVELGDFSDLLWRRALVTVAGIVVTVACWPLLRRFDARPLATR
VGAALVIMLPAALALAAVNQWAFAPVEKRMIERISTDQGDEAPTRTSQVTVKNGDGKGGAVKIRHDMAGNVLVDVLDEGF
VPPVPAPPPAPPPAPRTPHPTHAPGSTAHASPTTEPLLSEEDVAELRNLGDERTIEALKNAGIVQNPDGSTVISQPGLYV
RQYADGRSEVRTGGKVYVVGDDGEVESILSGARDPVPPEPPAPAASAVPPAPPAPPAPAISAAMQEKVREAARRETEKAL
GKADALRKAALARAREARARHADAHPVAQPSVSARPAVSAEPAASATPEPSPSEIVTEDYRGSDHVTIIRQTVENEGLWR
QLTDVALGRYFLLIAWAALYLALGNGEQLRAAEYREGEYRRAAKASELRSLRYQVNPHFLFNTLNSLSALVMVGRSEQAE
RMIQSISRFYRHSLAGDPTADVPLEDEIALQRHYLDIEAVRFPDRLRCEFDVPDDLMTACVPGMILQPLVENSIKYAVST
TIRPVTIRIAAREAGGFLILTVADDGPGESFVNGGTGIGLANVKSRLAARFGEDAAKVESGPLPAGGYATVLTLPIVRNE
C

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=203, Percent_Identity=37.9310344827586, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788723, Length=188, Percent_Identity=30.8510638297872, Blast_Score=102, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68779; Mature: 68648

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSQIDPGVPRVPARQVILSAVALWLCYFVLITVRGLVVELGDFSDLLWRRALVTVAGI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VVTVACWPLLRRFDARPLATRVGAALVIMLPAALALAAVNQWAFAPVEKRMIERISTDQG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
DEAPTRTSQVTVKNGDGKGGAVKIRHDMAGNVLVDVLDEGFVPPVPAPPPAPPPAPRTPH
CCCCCCCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PTHAPGSTAHASPTTEPLLSEEDVAELRNLGDERTIEALKNAGIVQNPDGSTVISQPGLY
CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCEECCCCCEEECCCCHH
VRQYADGRSEVRTGGKVYVVGDDGEVESILSGARDPVPPEPPAPAASAVPPAPPAPPAPA
HHHHCCCHHHHCCCCEEEEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
ISAAMQEKVREAARRETEKALGKADALRKAALARAREARARHADAHPVAQPSVSARPAVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
AEPAASATPEPSPSEIVTEDYRGSDHVTIIRQTVENEGLWRQLTDVALGRYFLLIAWAAL
CCCCCCCCCCCCCCHHHHHCCCCCCCEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
YLALGNGEQLRAAEYREGEYRRAAKASELRSLRYQVNPHFLFNTLNSLSALVMVGRSEQA
HHHCCCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHH
ERMIQSISRFYRHSLAGDPTADVPLEDEIALQRHYLDIEAVRFPDRLRCEFDVPDDLMTA
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCEEECCCCHHHHHH
CVPGMILQPLVENSIKYAVSTTIRPVTIRIAAREAGGFLILTVADDGPGESFVNGGTGIG
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEEECCCCCCHHCCCCCCCC
LANVKSRLAARFGEDAAKVESGPLPAGGYATVLTLPIVRNEC
HHHHHHHHHHHHCCHHHHCCCCCCCCCCCEEEEEECHHHCCC
>Mature Secondary Structure 
TLSQIDPGVPRVPARQVILSAVALWLCYFVLITVRGLVVELGDFSDLLWRRALVTVAGI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VVTVACWPLLRRFDARPLATRVGAALVIMLPAALALAAVNQWAFAPVEKRMIERISTDQG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
DEAPTRTSQVTVKNGDGKGGAVKIRHDMAGNVLVDVLDEGFVPPVPAPPPAPPPAPRTPH
CCCCCCCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PTHAPGSTAHASPTTEPLLSEEDVAELRNLGDERTIEALKNAGIVQNPDGSTVISQPGLY
CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCEECCCCCEEECCCCHH
VRQYADGRSEVRTGGKVYVVGDDGEVESILSGARDPVPPEPPAPAASAVPPAPPAPPAPA
HHHHCCCHHHHCCCCEEEEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
ISAAMQEKVREAARRETEKALGKADALRKAALARAREARARHADAHPVAQPSVSARPAVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
AEPAASATPEPSPSEIVTEDYRGSDHVTIIRQTVENEGLWRQLTDVALGRYFLLIAWAAL
CCCCCCCCCCCCCCHHHHHCCCCCCCEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
YLALGNGEQLRAAEYREGEYRRAAKASELRSLRYQVNPHFLFNTLNSLSALVMVGRSEQA
HHHCCCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHH
ERMIQSISRFYRHSLAGDPTADVPLEDEIALQRHYLDIEAVRFPDRLRCEFDVPDDLMTA
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCEEECCCCHHHHHH
CVPGMILQPLVENSIKYAVSTTIRPVTIRIAAREAGGFLILTVADDGPGESFVNGGTGIG
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEEECCCCCCHHCCCCCCCC
LANVKSRLAARFGEDAAKVESGPLPAGGYATVLTLPIVRNEC
HHHHHHHHHHHHCCHHHHCCCCCCCCCCCEEEEEECHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]