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The map label for this gene is groS

Identifier: 87198060

GI number: 87198060

Start: 35373

End: 35660

Strand: Direct

Name: groS

Synonym: Saro_0034

Alternate gene names: 87198060

Gene position: 35373-35660 (Clockwise)

Preceding gene: 87198059

Following gene: 87198061

Centisome position: 0.99

GC content: 63.54

Gene sequence:

>288_bases
ATGACTTTCCGTCCGCTGCACGATCGCGTGCTCGTACGCCGCGTCGAAGCCGAGGAAAAGACCGCCGGCGGCATCATCAT
CCCCGACAGCGCCAAGGAAAAGCCTGCCGAGGGCATCGTCGTCGCCGTTGGTTCGGGCGCCCGCGCCGAGAACGGCACGA
TCACCCCGCTCGACGTGAAGGCCAATGATCGCGTGCTGTTCGGCAAGTGGTCCGGCACCGAAGTCAAGGTCGACGGTGAA
GACCTGCTCATCATGAAGGAATCGGACATCCTCGGCGTGATCGGCTGA

Upstream 100 bases:

>100_bases
CCATTGACGGCCCATGACGAGGCACCCATATCCGCGCCGCTGGCACTCTCGGGTTGAGAGTGCCAAGACCCATTCAGTAA
CTTGGAAGAGGGAGCAATCC

Downstream 100 bases:

>100_bases
TCGACGCTGCTGTCCTGAAATCCACTCAAGAAATTCGAAGGAACAAGACATGGCTGCCAAGGACGTAAAGTTCGGCCGCG
ACGCTCGTGAACGCATTCTG

Product: chaperonin Cpn10

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 95; Mature: 94

Protein sequence:

>95_residues
MTFRPLHDRVLVRRVEAEEKTAGGIIIPDSAKEKPAEGIVVAVGSGARAENGTITPLDVKANDRVLFGKWSGTEVKVDGE
DLLIMKESDILGVIG

Sequences:

>Translated_95_residues
MTFRPLHDRVLVRRVEAEEKTAGGIIIPDSAKEKPAEGIVVAVGSGARAENGTITPLDVKANDRVLFGKWSGTEVKVDGE
DLLIMKESDILGVIG
>Mature_94_residues
TFRPLHDRVLVRRVEAEEKTAGGIIIPDSAKEKPAEGIVVAVGSGARAENGTITPLDVKANDRVLFGKWSGTEVKVDGED
LLIMKESDILGVIG

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Homo sapiens, GI4504523, Length=90, Percent_Identity=45.5555555555556, Blast_Score=72, Evalue=1e-13,
Organism=Homo sapiens, GI169210012, Length=90, Percent_Identity=44.4444444444444, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790585, Length=95, Percent_Identity=51.5789473684211, Blast_Score=94, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17555568, Length=93, Percent_Identity=49.4623655913978, Blast_Score=92, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6324594, Length=92, Percent_Identity=38.0434782608696, Blast_Score=64, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356029, Length=90, Percent_Identity=46.6666666666667, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21358317, Length=89, Percent_Identity=43.8202247191011, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_NOVAD (Q2GCC7)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_495317.1
- ProteinModelPortal:   Q2GCC7
- SMR:   Q2GCC7
- STRING:   Q2GCC7
- GeneID:   3916037
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_0034
- eggNOG:   COG0234
- HOGENOM:   HBG703377
- OMA:   FGQYAGQ
- PhylomeDB:   Q2GCC7
- BioCyc:   NARO279238:SARO_0034-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10155; Mature: 10024

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFRPLHDRVLVRRVEAEEKTAGGIIIPDSAKEKPAEGIVVAVGSGARAENGTITPLDVK
CCCCCCCHHEEEEECCCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEC
ANDRVLFGKWSGTEVKVDGEDLLIMKESDILGVIG
CCCEEEEEECCCCEEEECCCEEEEEECCCEEEECC
>Mature Secondary Structure 
TFRPLHDRVLVRRVEAEEKTAGGIIIPDSAKEKPAEGIVVAVGSGARAENGTITPLDVK
CCCCCCHHEEEEECCCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEC
ANDRVLFGKWSGTEVKVDGEDLLIMKESDILGVIG
CCCEEEEEECCCCEEEECCCEEEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA