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The map label for this gene is kdgR [H]

Identifier: 86751533

GI number: 86751533

Start: 5022408

End: 5023223

Strand: Reverse

Name: kdgR [H]

Synonym: RPB_4432

Alternate gene names: 86751533

Gene position: 5023223-5022408 (Counterclockwise)

Preceding gene: 86751536

Following gene: 86751524

Centisome position: 94.22

GC content: 65.32

Gene sequence:

>816_bases
ATGAACGCTGTTACGTTTATCGGAATGGTCGGGATGGGTGCTGAAAGTCAGTCGGTTGCACGCGCGGTCGATATCCTGCA
GCTGCTGTCCGACAACGGTTCGCTCGGCGTGCGTGAGATCGCCCGGCGCATGGAGTTGTCGCCGACCATCGTGCATCGGC
TGGTGAGCACGCTGGCCTCGACGGGCCTCGCGGAGCAGGCCCCGGACACCCAGAAGTACCGCATCGGCTATCGCGCATTC
CGCATCGGATCGTCGTTCCTGTCGCAGAACGATCTCGACCGCGCCAGCACGCCCGAACTGGTGGCACTCGCCGAACAGCA
TCAGATCAGCAGCTTCCTCGGCGTGCTACGTGGCGGCGCGATGGTCTATCTCAAGGTCGTCAAGAGCAACGGCCCGATCG
CGATCAACAATCAGCCCGGCTCGCTCGCCGCGATTCACTCCACCGCCTTCGGCAAGGTGATGCTCGCTGCGCTGCCCGAC
AAGGAGGCCGCCGAGGTGCTCGGCAAGGAACCCTACAAGCGGCTGACGAAGAAGACCAAGGTGACGTTCCGCGCGCTGCT
CGGTGAGTTGCGCGAGATCCGCGAGACCGGGATCGCGATTTCCGACGAGGAGAATCTGGTCAACGTCTATTCGGTCGGCG
CCGCTGTGCGGGACGCTTCGGGCGAGGTGATCGCCTCGCTCAGCGGTGCAGTGCCGCGACAGGGGATGACCAAGCGCGAG
ATCGAACACGTCAACGCGCTGGTGAAGTCGGCGGCCGACAGCGTCTCGCGCAAGATGGGGGCGCCGTCGGCGCCATCCGG
CGGCCGCGGGCGCTGA

Upstream 100 bases:

>100_bases
CATGAAACCATCGAACGCTGCACAGATTGCGGGACGAGCCGACAAGCGGTGAGCAGACGCCGTGCTTTCGGCTTGGAATC
CAGCCGCCCCGTCGCTATAG

Downstream 100 bases:

>100_bases
CGCAACTATTCGAGCGCCTCGAGGAGTTGCCGCAGCTCCGCGGGGGTGCCCATGCCGGACGCCACGATCTCGTCGACGCC
GACATCCTCATACGCCGCGA

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MNAVTFIGMVGMGAESQSVARAVDILQLLSDNGSLGVREIARRMELSPTIVHRLVSTLASTGLAEQAPDTQKYRIGYRAF
RIGSSFLSQNDLDRASTPELVALAEQHQISSFLGVLRGGAMVYLKVVKSNGPIAINNQPGSLAAIHSTAFGKVMLAALPD
KEAAEVLGKEPYKRLTKKTKVTFRALLGELREIRETGIAISDEENLVNVYSVGAAVRDASGEVIASLSGAVPRQGMTKRE
IEHVNALVKSAADSVSRKMGAPSAPSGGRGR

Sequences:

>Translated_271_residues
MNAVTFIGMVGMGAESQSVARAVDILQLLSDNGSLGVREIARRMELSPTIVHRLVSTLASTGLAEQAPDTQKYRIGYRAF
RIGSSFLSQNDLDRASTPELVALAEQHQISSFLGVLRGGAMVYLKVVKSNGPIAINNQPGSLAAIHSTAFGKVMLAALPD
KEAAEVLGKEPYKRLTKKTKVTFRALLGELREIRETGIAISDEENLVNVYSVGAAVRDASGEVIASLSGAVPRQGMTKRE
IEHVNALVKSAADSVSRKMGAPSAPSGGRGR
>Mature_271_residues
MNAVTFIGMVGMGAESQSVARAVDILQLLSDNGSLGVREIARRMELSPTIVHRLVSTLASTGLAEQAPDTQKYRIGYRAF
RIGSSFLSQNDLDRASTPELVALAEQHQISSFLGVLRGGAMVYLKVVKSNGPIAINNQPGSLAAIHSTAFGKVMLAALPD
KEAAEVLGKEPYKRLTKKTKVTFRALLGELREIRETGIAISDEENLVNVYSVGAAVRDASGEVIASLSGAVPRQGMTKRE
IEHVNALVKSAADSVSRKMGAPSAPSGGRGR

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=248, Percent_Identity=28.6290322580645, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1786468, Length=248, Percent_Identity=29.0322580645161, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87082359, Length=247, Percent_Identity=25.9109311740891, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786715, Length=251, Percent_Identity=23.1075697211155, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788581, Length=247, Percent_Identity=22.6720647773279, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789999, Length=253, Percent_Identity=25.6916996047431, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28755; Mature: 28755

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAVTFIGMVGMGAESQSVARAVDILQLLSDNGSLGVREIARRMELSPTIVHRLVSTLAS
CCCEEEEHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
TGLAEQAPDTQKYRIGYRAFRIGSSFLSQNDLDRASTPELVALAEQHQISSFLGVLRGGA
CCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
MVYLKVVKSNGPIAINNQPGSLAAIHSTAFGKVMLAALPDKEAAEVLGKEPYKRLTKKTK
EEEEEEEECCCCEEECCCCCCEEEHHHHHHHHHHHEECCCHHHHHHHCCCHHHHHHHHHH
VTFRALLGELREIRETGIAISDEENLVNVYSVGAAVRDASGEVIASLSGAVPRQGMTKRE
HHHHHHHHHHHHHHHHCCEECCCCCEEHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHH
IEHVNALVKSAADSVSRKMGAPSAPSGGRGR
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNAVTFIGMVGMGAESQSVARAVDILQLLSDNGSLGVREIARRMELSPTIVHRLVSTLAS
CCCEEEEHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
TGLAEQAPDTQKYRIGYRAFRIGSSFLSQNDLDRASTPELVALAEQHQISSFLGVLRGGA
CCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
MVYLKVVKSNGPIAINNQPGSLAAIHSTAFGKVMLAALPDKEAAEVLGKEPYKRLTKKTK
EEEEEEEECCCCEEECCCCCCEEEHHHHHHHHHHHEECCCHHHHHHHCCCHHHHHHHHHH
VTFRALLGELREIRETGIAISDEENLVNVYSVGAAVRDASGEVIASLSGAVPRQGMTKRE
HHHHHHHHHHHHHHHHCCEECCCCCEEHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHH
IEHVNALVKSAADSVSRKMGAPSAPSGGRGR
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]