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The map label for this gene is mmgC [H]

Identifier: 86751182

GI number: 86751182

Start: 4646391

End: 4647536

Strand: Reverse

Name: mmgC [H]

Synonym: RPB_4074

Alternate gene names: 86751182

Gene position: 4647536-4646391 (Counterclockwise)

Preceding gene: 86751183

Following gene: 86751181

Centisome position: 87.17

GC content: 63.96

Gene sequence:

>1146_bases
ATGCAGTATCGATCGCCCTGGATGACCGAGGAACTGGACACGTTCCGTGACCAGTTTCGCAAGTTCTTGGAGAAGGACCT
TGCGCCGCACGCCGAAAAATGGCGCAAGCAGAAGATGGTCGATCGCTCCGCCTGGCTCAAGCTCGGCGAGATGGGCGCGC
TGGTGCCGAGCGTGCCGGAGGCCTATGGCGGCCTCGGCGCCAGCTTCGCCTATGATGCCGCGATCTACGAGGACATGGAG
TCGATCGTGCCGGACGCATTGTCCGGCGTCACCGTGTCGAGCGGCATCGTCGCGCACTACATCCTGAACTACGGCTCGGA
AGAGCAGAAGCAGCGCTGGCTGCCGGCGATGGCGCGCGGTGAGCTGATCGGCGGCATCGCGATGACCGAGCCTGGCACCG
GCTCTGATCTGCAGAGCGTGCGCACCACGGCCAAGCTCGAGGGCGACACCTACGTCATCAACGGCCAGAAGACCTTCATC
ACCAATGGCCAGAACGCCGATCTGATCATCGTGGTGGCGCGCACCGGCGGGCCGGGCGCCAAGGGGCTGTCGCTGATCGC
GATGGAGACCAAAGACAATCCCGGCTTCAAGCGCGGCCGCAACCTCGACAAGATCGGCCTGCACGCCTCCGACACCTCCG
AATTGTTCTTCGACAACGCGACGGCGCCGAAAGAGAATGTGCTGGGCGGCGAAGAGGGCAAGGGTTTCGCCCAGCTGATG
CAGCAATTGCCGCAGGAGCGGCTGATCATCGCGGTCGGCGCGGTGGCGGCGATGGAGCGCGCCGTCAAGTTGACCACCGA
CTATACCCGCGAGCGCAAGGCGTTCGGCCAGCCGATCCTCGACTTCCAGAACACCGCCTTCACGCTCGCCGAGCGCAAGA
CCGAGGCGTTCATCGCCCGCGTGTTCGTCGATTTCTGCATCGAGCGGCTGATCGCCGGCGATCTCGACGCCGTCACGGCG
TCGATGGCGAAATGGTGGACCACGCAGAAGCAGGTCGAGACCGTCGACGAGTGCCTGCAACTGCACGGTGGCTACGGTTA
CATGCAGGAATATCCGATCGGCCGGATGTTCGTCGATGCGCGGATCCAGAAGATCTACGGCGGCACCAACGAGGTGATGA
AGCTGCTGATCGCGCGCTCGCTGTAG

Upstream 100 bases:

>100_bases
GGCGGCCGACGCGGTGTATCTGTTCTGCAGCCCGGAATCGAACTACATCAGTGGTCAGGTCGTCGTCTGCGGCGGCGGAC
TTATTCTGTAGCGAGGAAAA

Downstream 100 bases:

>100_bases
CGACCGCGACTGGCGAAGCAGCCCTGCAACGGGCAAGGGAGCGTGGCATGACGTGGGTGATGTCGGAGCAGCGCGGTGCG
GTCACCGTGCTGACGCTGAA

Product: Acyl-CoA dehydrogenase-like

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MQYRSPWMTEELDTFRDQFRKFLEKDLAPHAEKWRKQKMVDRSAWLKLGEMGALVPSVPEAYGGLGASFAYDAAIYEDME
SIVPDALSGVTVSSGIVAHYILNYGSEEQKQRWLPAMARGELIGGIAMTEPGTGSDLQSVRTTAKLEGDTYVINGQKTFI
TNGQNADLIIVVARTGGPGAKGLSLIAMETKDNPGFKRGRNLDKIGLHASDTSELFFDNATAPKENVLGGEEGKGFAQLM
QQLPQERLIIAVGAVAAMERAVKLTTDYTRERKAFGQPILDFQNTAFTLAERKTEAFIARVFVDFCIERLIAGDLDAVTA
SMAKWWTTQKQVETVDECLQLHGGYGYMQEYPIGRMFVDARIQKIYGGTNEVMKLLIARSL

Sequences:

>Translated_381_residues
MQYRSPWMTEELDTFRDQFRKFLEKDLAPHAEKWRKQKMVDRSAWLKLGEMGALVPSVPEAYGGLGASFAYDAAIYEDME
SIVPDALSGVTVSSGIVAHYILNYGSEEQKQRWLPAMARGELIGGIAMTEPGTGSDLQSVRTTAKLEGDTYVINGQKTFI
TNGQNADLIIVVARTGGPGAKGLSLIAMETKDNPGFKRGRNLDKIGLHASDTSELFFDNATAPKENVLGGEEGKGFAQLM
QQLPQERLIIAVGAVAAMERAVKLTTDYTRERKAFGQPILDFQNTAFTLAERKTEAFIARVFVDFCIERLIAGDLDAVTA
SMAKWWTTQKQVETVDECLQLHGGYGYMQEYPIGRMFVDARIQKIYGGTNEVMKLLIARSL
>Mature_381_residues
MQYRSPWMTEELDTFRDQFRKFLEKDLAPHAEKWRKQKMVDRSAWLKLGEMGALVPSVPEAYGGLGASFAYDAAIYEDME
SIVPDALSGVTVSSGIVAHYILNYGSEEQKQRWLPAMARGELIGGIAMTEPGTGSDLQSVRTTAKLEGDTYVINGQKTFI
TNGQNADLIIVVARTGGPGAKGLSLIAMETKDNPGFKRGRNLDKIGLHASDTSELFFDNATAPKENVLGGEEGKGFAQLM
QQLPQERLIIAVGAVAAMERAVKLTTDYTRERKAFGQPILDFQNTAFTLAERKTEAFIARVFVDFCIERLIAGDLDAVTA
SMAKWWTTQKQVETVDECLQLHGGYGYMQEYPIGRMFVDARIQKIYGGTNEVMKLLIARSL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=45.6233421750663, Blast_Score=334, Evalue=8e-92,
Organism=Homo sapiens, GI7656849, Length=375, Percent_Identity=33.0666666666667, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI226958412, Length=379, Percent_Identity=32.4538258575198, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI226958414, Length=340, Percent_Identity=32.9411764705882, Blast_Score=198, Evalue=5e-51,
Organism=Homo sapiens, GI4557233, Length=382, Percent_Identity=33.7696335078534, Blast_Score=191, Evalue=6e-49,
Organism=Homo sapiens, GI4557231, Length=380, Percent_Identity=31.5789473684211, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI187960098, Length=380, Percent_Identity=31.5789473684211, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=29.8666666666667, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI21361497, Length=390, Percent_Identity=31.5384615384615, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI76496475, Length=390, Percent_Identity=30.5128205128205, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI4557235, Length=361, Percent_Identity=31.3019390581717, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI4503943, Length=389, Percent_Identity=29.8200514138817, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI7669494, Length=374, Percent_Identity=29.9465240641711, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI211971008, Length=288, Percent_Identity=28.125, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI48976061, Length=288, Percent_Identity=28.125, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI38505218, Length=294, Percent_Identity=27.5510204081633, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI218563752, Length=289, Percent_Identity=23.8754325259516, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI87081958, Length=338, Percent_Identity=30.7692307692308, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1786223, Length=341, Percent_Identity=26.9794721407625, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI87082384, Length=288, Percent_Identity=26.7361111111111, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538396, Length=381, Percent_Identity=34.3832020997375, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17533517, Length=365, Percent_Identity=33.6986301369863, Blast_Score=201, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17551932, Length=370, Percent_Identity=32.1621621621622, Blast_Score=187, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI17570075, Length=378, Percent_Identity=30.952380952381, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17508101, Length=374, Percent_Identity=30.7486631016043, Blast_Score=184, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI17505929, Length=364, Percent_Identity=32.6923076923077, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17534899, Length=365, Percent_Identity=31.7808219178082, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17569725, Length=383, Percent_Identity=31.331592689295, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17506239, Length=377, Percent_Identity=30.7692307692308, Blast_Score=171, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI71985184, Length=354, Percent_Identity=31.638418079096, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI71990804, Length=284, Percent_Identity=33.8028169014084, Blast_Score=144, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17534353, Length=382, Percent_Identity=29.0575916230367, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI32563615, Length=227, Percent_Identity=32.15859030837, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI71985192, Length=309, Percent_Identity=30.7443365695793, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI71982178, Length=276, Percent_Identity=25, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17562446, Length=291, Percent_Identity=29.2096219931272, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI86563381, Length=275, Percent_Identity=28.7272727272727, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI86563383, Length=275, Percent_Identity=28.7272727272727, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI21355753, Length=383, Percent_Identity=34.4647519582245, Blast_Score=211, Evalue=5e-55,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=31.2, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=30.952380952381, Blast_Score=177, Evalue=8e-45,
Organism=Drosophila melanogaster, GI24646207, Length=379, Percent_Identity=31.6622691292876, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24666513, Length=376, Percent_Identity=28.7234042553192, Blast_Score=164, Evalue=7e-41,
Organism=Drosophila melanogaster, GI19920834, Length=383, Percent_Identity=29.242819843342, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI281363737, Length=382, Percent_Identity=29.8429319371728, Blast_Score=150, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42162; Mature: 42162

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYRSPWMTEELDTFRDQFRKFLEKDLAPHAEKWRKQKMVDRSAWLKLGEMGALVPSVPE
CCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
AYGGLGASFAYDAAIYEDMESIVPDALSGVTVSSGIVAHYILNYGSEEQKQRWLPAMARG
HHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHCHHHHCC
ELIGGIAMTEPGTGSDLQSVRTTAKLEGDTYVINGQKTFITNGQNADLIIVVARTGGPGA
HHHCCEEECCCCCCCHHHHHHHHHEECCCEEEECCCEEEEECCCCCCEEEEEEECCCCCC
KGLSLIAMETKDNPGFKRGRNLDKIGLHASDTSELFFDNATAPKENVLGGEEGKGFAQLM
CCEEEEEEECCCCCCHHCCCCCCCCCCCCCCCHHHEECCCCCCHHHCCCCCCCCHHHHHH
QQLPQERLIIAVGAVAAMERAVKLTTDYTRERKAFGQPILDFQNTAFTLAERKTEAFIAR
HHCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHH
VFVDFCIERLIAGDLDAVTASMAKWWTTQKQVETVDECLQLHGGYGYMQEYPIGRMFVDA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHH
RIQKIYGGTNEVMKLLIARSL
HHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MQYRSPWMTEELDTFRDQFRKFLEKDLAPHAEKWRKQKMVDRSAWLKLGEMGALVPSVPE
CCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
AYGGLGASFAYDAAIYEDMESIVPDALSGVTVSSGIVAHYILNYGSEEQKQRWLPAMARG
HHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHCHHHHCC
ELIGGIAMTEPGTGSDLQSVRTTAKLEGDTYVINGQKTFITNGQNADLIIVVARTGGPGA
HHHCCEEECCCCCCCHHHHHHHHHEECCCEEEECCCEEEEECCCCCCEEEEEEECCCCCC
KGLSLIAMETKDNPGFKRGRNLDKIGLHASDTSELFFDNATAPKENVLGGEEGKGFAQLM
CCEEEEEEECCCCCCHHCCCCCCCCCCCCCCCHHHEECCCCCCHHHCCCCCCCCHHHHHH
QQLPQERLIIAVGAVAAMERAVKLTTDYTRERKAFGQPILDFQNTAFTLAERKTEAFIAR
HHCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHH
VFVDFCIERLIAGDLDAVTASMAKWWTTQKQVETVDECLQLHGGYGYMQEYPIGRMFVDA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHH
RIQKIYGGTNEVMKLLIARSL
HHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]