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The map label for this gene is paaG [H]

Identifier: 86751181

GI number: 86751181

Start: 4645567

End: 4646343

Strand: Reverse

Name: paaG [H]

Synonym: RPB_4073

Alternate gene names: 86751181

Gene position: 4646343-4645567 (Counterclockwise)

Preceding gene: 86751182

Following gene: 86751178

Centisome position: 87.15

GC content: 70.01

Gene sequence:

>777_bases
ATGACGTGGGTGATGTCGGAGCAGCGCGGTGCGGTCACCGTGCTGACGCTGAACAATCCCGAGCAGTACAACGCGATGCG
CCGCGGTCTGCTCGGCGACCTGCACGCCGCACTGAGCGCGGCCCTCGCCGATCGTTCGGTGCGCGCGATCCTGCTCACCG
GCGCCGGCAAGGGATTCTGCGCCGGCGCCGAACTGGGCGGCGCCACGTTCGACGCCGGCGCGAATGTCGCGCCGTGGATG
CGCGCCGAACTCAGTCCGTTGCTCGAAATGATGCGTGACGCGGAGAAGCCGATCGTGGTGGCGGTGAACGGCCCGGCGGC
AGGCGCCGGTGTCGGTCTTGCGCTCGCCGGCGATATCGTGCTGGCGGCTCGCTCGGCGAAGTTCGTGCTGAGCTTCGTCA
AGCTCGGCGCCGCGCTCGATGCCGGCACCTCGCTGTTCCTGCAGCGCTCGATCGGGGTGGCGCGGGCGCGGGCGCTCGCG
CTGCTCGGCCGGCCGCTCGGCGCCGAACACGCGGCGCAATGGGGCCTGATCTATCAGGTCGTCGATGATGCCCAACTCAT
GACCGAGGCGATGGTGATCGCCGAGCAACTCGCGAACGGACCGCCGGTCAGCATCGGGCTTATCAAGCGCCAGATCGAGG
CCGCCTGGAGCGCACCGCTTGCCGCGACGCTCGACGACGAAGCCGAACGTCAGGGCCAGGCGTTCGTCACCGCCGATCTG
CGCGAAGGCGCCGCCGCCTTCGTCGAAAAGCGCCCGGCGCGGTTCACCGGACGATAG

Upstream 100 bases:

>100_bases
TCTACGGCGGCACCAACGAGGTGATGAAGCTGCTGATCGCGCGCTCGCTGTAGCGACCGCGACTGGCGAAGCAGCCCTGC
AACGGGCAAGGGAGCGTGGC

Downstream 100 bases:

>100_bases
ACGCGCTTACGCGTCCATCGTCTCCCGCACCAGGAAGCGCTCGCGCAGGGTCGGCTTGTGCACCTTGCCGGTGGCGTTGC
GTGGCAGCGCCTCGACGAAG

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MTWVMSEQRGAVTVLTLNNPEQYNAMRRGLLGDLHAALSAALADRSVRAILLTGAGKGFCAGAELGGATFDAGANVAPWM
RAELSPLLEMMRDAEKPIVVAVNGPAAGAGVGLALAGDIVLAARSAKFVLSFVKLGAALDAGTSLFLQRSIGVARARALA
LLGRPLGAEHAAQWGLIYQVVDDAQLMTEAMVIAEQLANGPPVSIGLIKRQIEAAWSAPLAATLDDEAERQGQAFVTADL
REGAAAFVEKRPARFTGR

Sequences:

>Translated_258_residues
MTWVMSEQRGAVTVLTLNNPEQYNAMRRGLLGDLHAALSAALADRSVRAILLTGAGKGFCAGAELGGATFDAGANVAPWM
RAELSPLLEMMRDAEKPIVVAVNGPAAGAGVGLALAGDIVLAARSAKFVLSFVKLGAALDAGTSLFLQRSIGVARARALA
LLGRPLGAEHAAQWGLIYQVVDDAQLMTEAMVIAEQLANGPPVSIGLIKRQIEAAWSAPLAATLDDEAERQGQAFVTADL
REGAAAFVEKRPARFTGR
>Mature_257_residues
TWVMSEQRGAVTVLTLNNPEQYNAMRRGLLGDLHAALSAALADRSVRAILLTGAGKGFCAGAELGGATFDAGANVAPWMR
AELSPLLEMMRDAEKPIVVAVNGPAAGAGVGLALAGDIVLAARSAKFVLSFVKLGAALDAGTSLFLQRSIGVARARALAL
LGRPLGAEHAAQWGLIYQVVDDAQLMTEAMVIAEQLANGPPVSIGLIKRQIEAAWSAPLAATLDDEAERQGQAFVTADLR
EGAAAFVEKRPARFTGR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=256, Percent_Identity=31.25, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI4502327, Length=258, Percent_Identity=30.6201550387597, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI25453481, Length=255, Percent_Identity=25.8823529411765, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI51538573, Length=255, Percent_Identity=25.8823529411765, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI221307494, Length=207, Percent_Identity=28.9855072463768, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI221136756, Length=207, Percent_Identity=28.9855072463768, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI221136753, Length=207, Percent_Identity=28.9855072463768, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4757966, Length=209, Percent_Identity=27.7511961722488, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI51538581, Length=209, Percent_Identity=27.7511961722488, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI31542718, Length=260, Percent_Identity=26.9230769230769, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI70995211, Length=260, Percent_Identity=28.8461538461538, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI4757968, Length=255, Percent_Identity=25.4901960784314, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI49355787, Length=255, Percent_Identity=25.4901960784314, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI45643119, Length=218, Percent_Identity=27.5229357798165, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI260275230, Length=218, Percent_Identity=27.5229357798165, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI260274832, Length=218, Percent_Identity=27.5229357798165, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI68989263, Length=206, Percent_Identity=30.5825242718447, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI116235487, Length=235, Percent_Identity=26.3829787234043, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI37594471, Length=255, Percent_Identity=24.7058823529412, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI37594469, Length=255, Percent_Identity=24.7058823529412, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI20127408, Length=181, Percent_Identity=28.7292817679558, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787660, Length=261, Percent_Identity=44.8275862068966, Blast_Score=170, Evalue=7e-44,
Organism=Escherichia coli, GI1787659, Length=258, Percent_Identity=32.1705426356589, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI221142681, Length=263, Percent_Identity=31.9391634980989, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788597, Length=262, Percent_Identity=29.0076335877863, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082183, Length=255, Percent_Identity=26.2745098039216, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI25145438, Length=245, Percent_Identity=32.6530612244898, Blast_Score=117, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17554946, Length=257, Percent_Identity=28.4046692607004, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17540306, Length=257, Percent_Identity=29.1828793774319, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17535521, Length=249, Percent_Identity=25.3012048192771, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17536985, Length=267, Percent_Identity=25.4681647940075, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17560910, Length=253, Percent_Identity=27.2727272727273, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17549921, Length=208, Percent_Identity=26.4423076923077, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17534483, Length=253, Percent_Identity=25.296442687747, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17540714, Length=226, Percent_Identity=26.9911504424779, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI20129971, Length=253, Percent_Identity=36.3636363636364, Blast_Score=137, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24653477, Length=253, Percent_Identity=36.3636363636364, Blast_Score=137, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24653139, Length=265, Percent_Identity=29.4339622641509, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24654903, Length=250, Percent_Identity=23.6, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI19920382, Length=225, Percent_Identity=27.5555555555556, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357171, Length=203, Percent_Identity=31.5270935960591, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI19922422, Length=260, Percent_Identity=25.3846153846154, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 26869; Mature: 26738

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWVMSEQRGAVTVLTLNNPEQYNAMRRGLLGDLHAALSAALADRSVRAILLTGAGKGFC
CCEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEE
AGAELGGATFDAGANVAPWMRAELSPLLEMMRDAEKPIVVAVNGPAAGAGVGLALAGDIV
CCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHH
LAARSAKFVLSFVKLGAALDAGTSLFLQRSIGVARARALALLGRPLGAEHAAQWGLIYQV
EEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
VDDAQLMTEAMVIAEQLANGPPVSIGLIKRQIEAAWSAPLAATLDDEAERQGQAFVTADL
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEECCCCHHHHCCCEEEEECH
REGAAAFVEKRPARFTGR
HHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TWVMSEQRGAVTVLTLNNPEQYNAMRRGLLGDLHAALSAALADRSVRAILLTGAGKGFC
CEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEE
AGAELGGATFDAGANVAPWMRAELSPLLEMMRDAEKPIVVAVNGPAAGAGVGLALAGDIV
CCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHH
LAARSAKFVLSFVKLGAALDAGTSLFLQRSIGVARARALALLGRPLGAEHAAQWGLIYQV
EEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
VDDAQLMTEAMVIAEQLANGPPVSIGLIKRQIEAAWSAPLAATLDDEAERQGQAFVTADL
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEECCCCHHHHCCCEEEEECH
REGAAAFVEKRPARFTGR
HHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]