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The map label for this gene is ttuD [H]

Identifier: 86750677

GI number: 86750677

Start: 4088395

End: 4089675

Strand: Direct

Name: ttuD [H]

Synonym: RPB_3567

Alternate gene names: 86750677

Gene position: 4088395-4089675 (Clockwise)

Preceding gene: 86750676

Following gene: 86750679

Centisome position: 76.68

GC content: 72.44

Gene sequence:

>1281_bases
ATGACCGACCAACGTCCCCTGCTCCGCGCGCTGTTCGACGCCGCCGTCGCGGCCGCGCATCCGGACAGCATTCTCGCCGC
GCATCTGCCGCCGCTGCCGCGCGGCCGGATCATCTGCCTCGCCGCCGGCAAGGGTGCCGCCGCGATGGCCGCCGCCGCGG
AGCGGCATTATCTCGACACGCTCGGGCTCGCGCCCTCACGTCTGATCGGCATCGCCACCACCCGCCACGGCCATCGCGTG
GCGACCCGCGCCATCGACGTGATCGAGGCCGGGCACCCGATGCCCGACGCCGAAGGGCTGCGCGGTGCCGAAGCGAGCCT
GAAGCTCGCCGCCACCGCGACCGCCGACGATCTGCTGCTGGTGCTGCTGTCGGGCGGCGGCTCGGCGAACTGGATCCTGC
CGGCCGACGGCATCACGCTCGCGCAAAAGCAGGCCACCACGCGCGCGCTGCTGCGCTCCGGCGCGCCGATCGGCGAGGTC
AACACCGTCCGCAAGCATCTGTCGCGGATCAAGGGCGGCCGCCTCGCTTGCGCCGGCAGCAGCGCCGCCGAAATCGTGAC
GCTGGCGATTTCCGACGTGCCGCGCGACGAGGCATCGGCGATAGCGTCCGGGCCGACCGTGCCCGATCCGACGACGCTGG
ACGACGCCCGCGCACTGGTGGCGCGCTACAAGCTCGACATCGACGACGCAGTCCATGCCGCGCTGAATGATCCACGCAAC
GAAAGCTGCAAGCCGGGCGACGCCGCTTTCGCCCGCGCCCGCTTCGCCATCATCGCGCGGCCGCGGCAATCGCTGGACGC
CGCGATCAAGCTGGCGCGCGATTCCGGCTATGCGATCGCCGATCTCGGCGCCGATCTCGAAGGCGAAGCCCGCGACGTGG
CTGCCGCCCACGCCCGGCTCGCGCGCGAGGCCCGTGCGGCCGGCAGGCGGCTCGCGATCATCTCCGGCGGCGAACTCACC
GTCACCGTGCGCGGCAACGGCCGCGGCGGCCCCAACCAGGAATATGCGCTGGCGCTGGCGCAGCACCTGCGCGACCTGCC
GGACATCGCAGCCCTCGCCGCCGACACCGACGGCGCCGACGGCGGCGCCGGCCACGCCACCGACCCCGCCGGCGCGCTGA
TCGACGCCCGCACCTTCGCGAAGATCGACGAGCGCGATCTCGACCCTACCGCCTATCTGGCGAACAACGACGCTACCGGC
TTCTTCGACCAGACCGGCGACCTGCTCGTCACCGGCCCGACGCTGACCAACGTCAACGATATCCGGGTGATCCTGGTGTA
G

Upstream 100 bases:

>100_bases
GTCGCGACGGCACCCTCTCCCACAAAGGGAGAGGGTTTGCAGGCGCACCGTCTCTCGCCCAGCCCTTGCCGCGTCCCGGC
CGGCCTGCGACAACGGCAGC

Downstream 100 bases:

>100_bases
TCGGCCCCTCCCCGTCATTGCGAGCGCAAGCGAAGCAATCCAGAGGCTCCGCGCACCGAGCCCCTGGATTGCTTCGTCGC
TTCGCTCCTCGCAATGACGG

Product: hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MTDQRPLLRALFDAAVAAAHPDSILAAHLPPLPRGRIICLAAGKGAAAMAAAAERHYLDTLGLAPSRLIGIATTRHGHRV
ATRAIDVIEAGHPMPDAEGLRGAEASLKLAATATADDLLLVLLSGGGSANWILPADGITLAQKQATTRALLRSGAPIGEV
NTVRKHLSRIKGGRLACAGSSAAEIVTLAISDVPRDEASAIASGPTVPDPTTLDDARALVARYKLDIDDAVHAALNDPRN
ESCKPGDAAFARARFAIIARPRQSLDAAIKLARDSGYAIADLGADLEGEARDVAAAHARLAREARAAGRRLAIISGGELT
VTVRGNGRGGPNQEYALALAQHLRDLPDIAALAADTDGADGGAGHATDPAGALIDARTFAKIDERDLDPTAYLANNDATG
FFDQTGDLLVTGPTLTNVNDIRVILV

Sequences:

>Translated_426_residues
MTDQRPLLRALFDAAVAAAHPDSILAAHLPPLPRGRIICLAAGKGAAAMAAAAERHYLDTLGLAPSRLIGIATTRHGHRV
ATRAIDVIEAGHPMPDAEGLRGAEASLKLAATATADDLLLVLLSGGGSANWILPADGITLAQKQATTRALLRSGAPIGEV
NTVRKHLSRIKGGRLACAGSSAAEIVTLAISDVPRDEASAIASGPTVPDPTTLDDARALVARYKLDIDDAVHAALNDPRN
ESCKPGDAAFARARFAIIARPRQSLDAAIKLARDSGYAIADLGADLEGEARDVAAAHARLAREARAAGRRLAIISGGELT
VTVRGNGRGGPNQEYALALAQHLRDLPDIAALAADTDGADGGAGHATDPAGALIDARTFAKIDERDLDPTAYLANNDATG
FFDQTGDLLVTGPTLTNVNDIRVILV
>Mature_425_residues
TDQRPLLRALFDAAVAAAHPDSILAAHLPPLPRGRIICLAAGKGAAAMAAAAERHYLDTLGLAPSRLIGIATTRHGHRVA
TRAIDVIEAGHPMPDAEGLRGAEASLKLAATATADDLLLVLLSGGGSANWILPADGITLAQKQATTRALLRSGAPIGEVN
TVRKHLSRIKGGRLACAGSSAAEIVTLAISDVPRDEASAIASGPTVPDPTTLDDARALVARYKLDIDDAVHAALNDPRNE
SCKPGDAAFARARFAIIARPRQSLDAAIKLARDSGYAIADLGADLEGEARDVAAAHARLAREARAAGRRLAIISGGELTV
TVRGNGRGGPNQEYALALAQHLRDLPDIAALAADTDGADGGAGHATDPAGALIDARTFAKIDERDLDPTAYLANNDATGF
FDQTGDLLVTGPTLTNVNDIRVILV

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=490, Percent_Identity=33.469387755102, Blast_Score=164, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI193205461, Length=467, Percent_Identity=27.6231263383298, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI19920578, Length=381, Percent_Identity=29.9212598425197, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 43963; Mature: 43832

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQRPLLRALFDAAVAAAHPDSILAAHLPPLPRGRIICLAAGKGAAAMAAAAERHYLDT
CCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHH
LGLAPSRLIGIATTRHGHRVATRAIDVIEAGHPMPDAEGLRGAEASLKLAATATADDLLL
HCCCHHHEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCEEE
VLLSGGGSANWILPADGITLAQKQATTRALLRSGAPIGEVNTVRKHLSRIKGGRLACAGS
EEEECCCCCCEEEECCCCEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCC
SAAEIVTLAISDVPRDEASAIASGPTVPDPTTLDDARALVARYKLDIDDAVHAALNDPRN
CCCEEEEEEECCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCC
ESCKPGDAAFARARFAIIARPRQSLDAAIKLARDSGYAIADLGADLEGEARDVAAAHARL
CCCCCCHHHHHHHEEEEEECCHHHHHHHHEECCCCCCEEEECCCCCCCCHHHHHHHHHHH
AREARAAGRRLAIISGGELTVTVRGNGRGGPNQEYALALAQHLRDLPDIAALAADTDGAD
HHHHHHCCCEEEEEECCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCC
GGAGHATDPAGALIDARTFAKIDERDLDPTAYLANNDATGFFDQTGDLLVTGPTLTNVND
CCCCCCCCCCCCEECHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCEEEECCCCCCCCC
IRVILV
EEEEEC
>Mature Secondary Structure 
TDQRPLLRALFDAAVAAAHPDSILAAHLPPLPRGRIICLAAGKGAAAMAAAAERHYLDT
CCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHH
LGLAPSRLIGIATTRHGHRVATRAIDVIEAGHPMPDAEGLRGAEASLKLAATATADDLLL
HCCCHHHEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCEEE
VLLSGGGSANWILPADGITLAQKQATTRALLRSGAPIGEVNTVRKHLSRIKGGRLACAGS
EEEECCCCCCEEEECCCCEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCC
SAAEIVTLAISDVPRDEASAIASGPTVPDPTTLDDARALVARYKLDIDDAVHAALNDPRN
CCCEEEEEEECCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCC
ESCKPGDAAFARARFAIIARPRQSLDAAIKLARDSGYAIADLGADLEGEARDVAAAHARL
CCCCCCHHHHHHHEEEEEECCHHHHHHHHEECCCCCCEEEECCCCCCCCHHHHHHHHHHH
AREARAAGRRLAIISGGELTVTVRGNGRGGPNQEYALALAQHLRDLPDIAALAADTDGAD
HHHHHHCCCEEEEEECCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCC
GGAGHATDPAGALIDARTFAKIDERDLDPTAYLANNDATGFFDQTGDLLVTGPTLTNVND
CCCCCCCCCCCCEECHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCEEEECCCCCCCCC
IRVILV
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]