BacMap

Definition	Rhodopseudomonas palustris HaA2, complete genome.
Accession	NC_007778
Length	5,331,656

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The map label for this gene is fabG [C]

Identifier: 86750316

GI number: 86750316

Start: 3667108

End: 3668025

Strand: Reverse

Name: fabG [C]

Synonym: RPB_3205

Alternate gene names: 86750316

Gene position: 3668025-3667108 (Counterclockwise)

Preceding gene: 86750317

Following gene: 86750315

Centisome position: 68.8

GC content: 67.32

Gene sequence:

>918_bases
ATGGCTATCAGGTTCGACGGACGCGTCGCCATCGTCACCGGCGCGGGCAACGGTTTGGGGCGCGCGCATGCGCTGGGCCT
CGCGGCGCGCGGCGCCAAGGTGGTGGTCAACGATTTCGGCGGCGCGCGCGACGGCACCGGCGGCTCGATGACCGCGGCCG
AGACGGTGGTCGAGGAGATCCGCAAGGCCGGCGGCACCGCGATGGCCGACGGCGCCGATGTCTCCAACTACGAGCAGGTG
AAGGCGATGGTCGCGAAAGCGACCAAGGAGTGGGGCAGCGTCGATCTGATGGTGGCGAATGCCGGCATCCTGCGCGACAA
ATCCTTCGGCAAGATGGAGCTCTCCGATTTCCAGAAGGTGATCGACGTGCATCTCGCCGGCACGTTCTACTGCTGCAAGG
CGGTGTGGGACGGCATGAAGGAGCGCAACTACGGCCGCATCGTGCTGACCACCTCGTCGTCGGGCATGTTCGGCAATTTC
GGCCAGGCCAATTACGGCGCGGCCAAAGCCGGCATCGTCGGGCTGATGAACGTGCTGGCGCAGGAGGGCCGCAAGACCGA
CATCCGCGTCAACACCGTGTCGCCGACGGCCGCGACCCGGATGACCGAAGAGCTGCTGCCGCCGCAGGCGCTGCAATTGA
TGAAGCCGGAGGCGATCACCCCGGCGGTGCTGTTCCTGCTCAGCGACAACGCGCCCACCCGCACCACGCTCGGCGCCGGC
GCCGGCTCGTTCGCGCAGATCAAGATCATCGAGACCGAAGGCATCAACCTGCCGGAGGAGGAGTGGACCCCCGACGCGAT
CGCCGCGCACTTCGCCGAGATCAGCGACGACTCCAAGGCGCAGGCGCTGGAAGGCGCATTCCAGCAGACGCAGAAATACG
TCGCGCAGGCCGCGGCGAGGCTCGGCCTCAAGATGTGA

Upstream 100 bases:

>100_bases
CCAGCGTCAACATCGAAATCGAGGGCGAGAAGCGCTCGGCGCTGGTCGCCGACTGGCTCGGCCTGATCTACTTCGAACAA
TAATCCGGGAAACAACACAC

Downstream 100 bases:

>100_bases
GGCCGACCTCTGTCGTCATTCCGGGGCGCGCGCAGCGCGAACCCGGAATCTCCGGTTGCAGAACATCTCGGGATTCCGGG
TTCGCTCGCTGCGCGAGCGC

Product: short-chain dehydrogenase/reductase SDR

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MAIRFDGRVAIVTGAGNGLGRAHALGLAARGAKVVVNDFGGARDGTGGSMTAAETVVEEIRKAGGTAMADGADVSNYEQV
KAMVAKATKEWGSVDLMVANAGILRDKSFGKMELSDFQKVIDVHLAGTFYCCKAVWDGMKERNYGRIVLTTSSSGMFGNF
GQANYGAAKAGIVGLMNVLAQEGRKTDIRVNTVSPTAATRMTEELLPPQALQLMKPEAITPAVLFLLSDNAPTRTTLGAG
AGSFAQIKIIETEGINLPEEEWTPDAIAAHFAEISDDSKAQALEGAFQQTQKYVAQAAARLGLKM

Sequences:

>Translated_305_residues
MAIRFDGRVAIVTGAGNGLGRAHALGLAARGAKVVVNDFGGARDGTGGSMTAAETVVEEIRKAGGTAMADGADVSNYEQV
KAMVAKATKEWGSVDLMVANAGILRDKSFGKMELSDFQKVIDVHLAGTFYCCKAVWDGMKERNYGRIVLTTSSSGMFGNF
GQANYGAAKAGIVGLMNVLAQEGRKTDIRVNTVSPTAATRMTEELLPPQALQLMKPEAITPAVLFLLSDNAPTRTTLGAG
AGSFAQIKIIETEGINLPEEEWTPDAIAAHFAEISDDSKAQALEGAFQQTQKYVAQAAARLGLKM
>Mature_304_residues
AIRFDGRVAIVTGAGNGLGRAHALGLAARGAKVVVNDFGGARDGTGGSMTAAETVVEEIRKAGGTAMADGADVSNYEQVK
AMVAKATKEWGSVDLMVANAGILRDKSFGKMELSDFQKVIDVHLAGTFYCCKAVWDGMKERNYGRIVLTTSSSGMFGNFG
QANYGAAKAGIVGLMNVLAQEGRKTDIRVNTVSPTAATRMTEELLPPQALQLMKPEAITPAVLFLLSDNAPTRTTLGAGA
GSFAQIKIIETEGINLPEEEWTPDAIAAHFAEISDDSKAQALEGAFQQTQKYVAQAAARLGLKM

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=288, Percent_Identity=45.1388888888889, Blast_Score=242, Evalue=3e-64,
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=32.9457364341085, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4503817, Length=225, Percent_Identity=27.1111111111111, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4758504, Length=201, Percent_Identity=33.8308457711443, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI40254992, Length=228, Percent_Identity=31.5789473684211, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI109715829, Length=250, Percent_Identity=30.8, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI210032110, Length=192, Percent_Identity=31.7708333333333, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI25282469, Length=262, Percent_Identity=27.0992366412214, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI83715985, Length=188, Percent_Identity=33.5106382978723, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI40807363, Length=229, Percent_Identity=29.6943231441048, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI310128830, Length=199, Percent_Identity=28.1407035175879, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI310115468, Length=199, Percent_Identity=28.1407035175879, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI32483357, Length=257, Percent_Identity=27.6264591439689, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI19923817, Length=246, Percent_Identity=26.8292682926829, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI142976729, Length=176, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=37.6569037656904, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787905, Length=238, Percent_Identity=32.3529411764706, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082100, Length=193, Percent_Identity=33.160621761658, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789208, Length=206, Percent_Identity=27.6699029126214, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1790717, Length=206, Percent_Identity=28.6407766990291, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789057, Length=237, Percent_Identity=31.2236286919831, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI2367175, Length=243, Percent_Identity=30.8641975308642, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787526, Length=234, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787820, Length=188, Percent_Identity=28.7234042553192, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082160, Length=206, Percent_Identity=28.6407766990291, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788459, Length=200, Percent_Identity=30.5, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786812, Length=247, Percent_Identity=25.9109311740891, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=299, Percent_Identity=42.4749163879599, Blast_Score=239, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI25147288, Length=241, Percent_Identity=32.3651452282158, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17555706, Length=236, Percent_Identity=31.7796610169492, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17564282, Length=196, Percent_Identity=33.1632653061224, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193203117, Length=237, Percent_Identity=29.1139240506329, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193203115, Length=274, Percent_Identity=28.4671532846715, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17567345, Length=197, Percent_Identity=31.9796954314721, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=201, Percent_Identity=34.3283582089552, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=29.4820717131474, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=189, Percent_Identity=27.5132275132275, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71982365, Length=199, Percent_Identity=31.6582914572864, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=225, Percent_Identity=29.3333333333333, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=200, Percent_Identity=30, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=277, Percent_Identity=45.8483754512635, Blast_Score=247, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6324126, Length=193, Percent_Identity=29.0155440414508, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI18859837, Length=285, Percent_Identity=44.9122807017544, Blast_Score=236, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24639444, Length=235, Percent_Identity=34.8936170212766, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24649181, Length=194, Percent_Identity=33.5051546391753, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI281364892, Length=193, Percent_Identity=28.4974093264249, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24640492, Length=194, Percent_Identity=27.8350515463918, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21355631, Length=181, Percent_Identity=32.5966850828729, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17737361, Length=199, Percent_Identity=32.1608040201005, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356301, Length=230, Percent_Identity=27.3913043478261, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI116007236, Length=240, Percent_Identity=27.9166666666667, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24581726, Length=217, Percent_Identity=25.8064516129032, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648693, Length=241, Percent_Identity=29.4605809128631, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21355889, Length=241, Percent_Identity=29.4605809128631, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21357673, Length=258, Percent_Identity=27.5193798449612, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI116007234, Length=241, Percent_Identity=28.2157676348548, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357041, Length=192, Percent_Identity=27.6041666666667, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI23397609, Length=196, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 32093; Mature: 31962

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIRFDGRVAIVTGAGNGLGRAHALGLAARGAKVVVNDFGGARDGTGGSMTAAETVVEEI
CEEEECCEEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHH
RKAGGTAMADGADVSNYEQVKAMVAKATKEWGSVDLMVANAGILRDKSFGKMELSDFQKV
HHCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCEEECCCCCCCCHHHHHHH
IDVHLAGTFYCCKAVWDGMKERNYGRIVLTTSSSGMFGNFGQANYGAAKAGIVGLMNVLA
HHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH
QEGRKTDIRVNTVSPTAATRMTEELLPPQALQLMKPEAITPAVLFLLSDNAPTRTTLGAG
HCCCCCEEEEEECCCHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEECCCCCCCEEECCC
AGSFAQIKIIETEGINLPEEEWTPDAIAAHFAEISDDSKAQALEGAFQQTQKYVAQAAAR
CCCEEEEEEEEECCCCCCHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LGLKM
HCCCC
>Mature Secondary Structure 
AIRFDGRVAIVTGAGNGLGRAHALGLAARGAKVVVNDFGGARDGTGGSMTAAETVVEEI
EEEECCEEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHH
RKAGGTAMADGADVSNYEQVKAMVAKATKEWGSVDLMVANAGILRDKSFGKMELSDFQKV
HHCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCEEECCCCCCCCHHHHHHH
IDVHLAGTFYCCKAVWDGMKERNYGRIVLTTSSSGMFGNFGQANYGAAKAGIVGLMNVLA
HHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH
QEGRKTDIRVNTVSPTAATRMTEELLPPQALQLMKPEAITPAVLFLLSDNAPTRTTLGAG
HCCCCCEEEEEECCCHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEECCCCCCCEEECCC
AGSFAQIKIIETEGINLPEEEWTPDAIAAHFAEISDDSKAQALEGAFQQTQKYVAQAAAR
CCCEEEEEEEEECCCCCCHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LGLKM
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]