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The map label for this gene is ribD [H]

Identifier: 86749753

GI number: 86749753

Start: 3016487

End: 3017656

Strand: Direct

Name: ribD [H]

Synonym: RPB_2636

Alternate gene names: 86749753

Gene position: 3016487-3017656 (Clockwise)

Preceding gene: 86749752

Following gene: 86749754

Centisome position: 56.58

GC content: 71.11

Gene sequence:

>1170_bases
ATGATCTTCCGCATCCTGGAAGACCAATATGCCGAGCGCGCCAAGGTCGAAAAGGCCGCCAAGGCAGCCGCCGCCACTGA
TCGCCGCTTCATGCAGCTCGCGCTGACGCTCGGCCGCCGTGGCCTCGGCCGCACTGGCACCAACCCCGCGGTCGGCGCGG
TGCTGGTCAAGGACGGCGTCATCGTCGGCCGCGGCTGGACCCAGGACGGTGGCCGGCCGCACGCCGAAGTCGAAGCGCTG
GCGCGGGCCGGCGAGGCCGCGCGCGGCGCGACGTTGTATGTGACGCTGGAGCCGTGCTCGCATCACGGCCGCTCGCCGCC
CTGCGCCGATGCGATCATCGCCGCGGGCGTCGCCCGGGTGGTGTCGGCGATCGAGGATCCCAATCCGCTGGTGGGCGGGC
AGGGCCATGGCAAGCTGCGCGCCGCCGGCATCGCGGTCGAGCTCGGGGTTTGCGTCGAGGAAGCCGCGCGCGATCACGCC
GGCCATCTGTTGCGCGTGCGCGAGCAGCGTCCGCATGTCGTGCTCAAGCTCGCAGTCTCGACCGACGACAAGATCGCGGC
TGACGGCCGCAAGCCTGTGGCGATCACCGGCGAGGCTGCGCGGGCGCGGGTGCATTTGCTGCGCGCGCAGTCGGATGCGA
TCCTGGTCGGGATCGGCACCGTGCTGGCCGACGATCCGGAACTGACCGTGCGGCTACCGGGAATGGCGAAACAATCACCG
ATCCGCGTGGTGCTGGACCGCGCTCTGCGCATCCCGGGAGACAGCAAGCTGGTGCATTCGGCGCGGGCGACGCCGCTGTG
GCTGATGGCATCCGAGATCGCCGAGCCGGCCGCGGCCGCGCGGCTCGGGGCGGCGGGGGCCGAGGTCATCCGCGCTCCCG
ATTGTCAACGAACGCCCGGACTCGACATCGCCGCAGTCCTGGCCGCTTTGTCCGAAAAGGGCGTCACCCGGCTCCTGGTC
GAGGGCGGGGCGCGGGCCGCGCGGGCGTTCGTCGAGTCCGGTCTCGTCGACGAGATCTGGCTGTTGCGTGGCGACAAGGC
GATCGGCGAAGACGGCGTCGACGCCCTGGACGGTTTGCCGCTCGCCTCCATCACCGCGTCGTCGGCTTGGCGCGTCCGCG
ACAGCGAACGCCTCGGACCGGACACGCTCACGATTTTCGAACCGGCTTAA

Upstream 100 bases:

>100_bases
TCGCCTCGGTGTATCGCAATTTCCGCGAGGCCAAGGACTTCGAGGCGGTGCTCGGCGAATTGTCCGGCGAGGAGGAGGCC
CGGCCGGCGCTGGTCCGCAA

Downstream 100 bases:

>100_bases
GGTCTGCGTCTCATGTTCACCGGCATTGTCACCGACATCGGCGAAATCGAAGCCCTGACGCCCACGGCGCAGGGACAACT
GCACCGGCTGCGGATCGGCT

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MIFRILEDQYAERAKVEKAAKAAAATDRRFMQLALTLGRRGLGRTGTNPAVGAVLVKDGVIVGRGWTQDGGRPHAEVEAL
ARAGEAARGATLYVTLEPCSHHGRSPPCADAIIAAGVARVVSAIEDPNPLVGGQGHGKLRAAGIAVELGVCVEEAARDHA
GHLLRVREQRPHVVLKLAVSTDDKIAADGRKPVAITGEAARARVHLLRAQSDAILVGIGTVLADDPELTVRLPGMAKQSP
IRVVLDRALRIPGDSKLVHSARATPLWLMASEIAEPAAAARLGAAGAEVIRAPDCQRTPGLDIAAVLAALSEKGVTRLLV
EGGARAARAFVESGLVDEIWLLRGDKAIGEDGVDALDGLPLASITASSAWRVRDSERLGPDTLTIFEPA

Sequences:

>Translated_389_residues
MIFRILEDQYAERAKVEKAAKAAAATDRRFMQLALTLGRRGLGRTGTNPAVGAVLVKDGVIVGRGWTQDGGRPHAEVEAL
ARAGEAARGATLYVTLEPCSHHGRSPPCADAIIAAGVARVVSAIEDPNPLVGGQGHGKLRAAGIAVELGVCVEEAARDHA
GHLLRVREQRPHVVLKLAVSTDDKIAADGRKPVAITGEAARARVHLLRAQSDAILVGIGTVLADDPELTVRLPGMAKQSP
IRVVLDRALRIPGDSKLVHSARATPLWLMASEIAEPAAAARLGAAGAEVIRAPDCQRTPGLDIAAVLAALSEKGVTRLLV
EGGARAARAFVESGLVDEIWLLRGDKAIGEDGVDALDGLPLASITASSAWRVRDSERLGPDTLTIFEPA
>Mature_389_residues
MIFRILEDQYAERAKVEKAAKAAAATDRRFMQLALTLGRRGLGRTGTNPAVGAVLVKDGVIVGRGWTQDGGRPHAEVEAL
ARAGEAARGATLYVTLEPCSHHGRSPPCADAIIAAGVARVVSAIEDPNPLVGGQGHGKLRAAGIAVELGVCVEEAARDHA
GHLLRVREQRPHVVLKLAVSTDDKIAADGRKPVAITGEAARARVHLLRAQSDAILVGIGTVLADDPELTVRLPGMAKQSP
IRVVLDRALRIPGDSKLVHSARATPLWLMASEIAEPAAAARLGAAGAEVIRAPDCQRTPGLDIAAVLAALSEKGVTRLLV
EGGARAARAFVESGLVDEIWLLRGDKAIGEDGVDALDGLPLASITASSAWRVRDSERLGPDTLTIFEPA

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=368, Percent_Identity=40.7608695652174, Blast_Score=239, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40679; Mature: 40679

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFRILEDQYAERAKVEKAAKAAAATDRRFMQLALTLGRRGLGRTGTNPAVGAVLVKDGV
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCE
IVGRGWTQDGGRPHAEVEALARAGEAARGATLYVTLEPCSHHGRSPPCADAIIAAGVARV
EEECCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCHHCCCCCCCHHHHHHHHHHHHH
VSAIEDPNPLVGGQGHGKLRAAGIAVELGVCVEEAARDHAGHLLRVREQRPHVVLKLAVS
HHHHCCCCCCCCCCCCCCEEEEEEEEEEHHHHHHHHHHHHCCEEEECCCCCCEEEEEEEC
TDDKIAADGRKPVAITGEAARARVHLLRAQSDAILVGIGTVLADDPELTVRLPGMAKQSP
CCCCEECCCCCCEEEECHHHHHHHHEEECCCCEEEEEECHHCCCCCCEEEECCCCCCCCC
IRVVLDRALRIPGDSKLVHSARATPLWLMASEIAEPAAAARLGAAGAEVIRAPDCQRTPG
HHHHHHHHHCCCCCCHHHHHCCCCCCEEHHHHHCCHHHHHHHCCCCHHHHCCCCCCCCCC
LDIAAVLAALSEKGVTRLLVEGGARAARAFVESGLVDEIWLLRGDKAIGEDGVDALDGLP
CCHHHHHHHHHHCCCEEEEHHCCHHHHHHHHHCCCHHHHHEEECCCCCCCCCCHHHCCCC
LASITASSAWRVRDSERLGPDTLTIFEPA
CCEECCCCCEEECCCCCCCCCEEEEECCC
>Mature Secondary Structure
MIFRILEDQYAERAKVEKAAKAAAATDRRFMQLALTLGRRGLGRTGTNPAVGAVLVKDGV
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCE
IVGRGWTQDGGRPHAEVEALARAGEAARGATLYVTLEPCSHHGRSPPCADAIIAAGVARV
EEECCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCHHCCCCCCCHHHHHHHHHHHHH
VSAIEDPNPLVGGQGHGKLRAAGIAVELGVCVEEAARDHAGHLLRVREQRPHVVLKLAVS
HHHHCCCCCCCCCCCCCCEEEEEEEEEEHHHHHHHHHHHHCCEEEECCCCCCEEEEEEEC
TDDKIAADGRKPVAITGEAARARVHLLRAQSDAILVGIGTVLADDPELTVRLPGMAKQSP
CCCCEECCCCCCEEEECHHHHHHHHEEECCCCEEEEEECHHCCCCCCEEEECCCCCCCCC
IRVVLDRALRIPGDSKLVHSARATPLWLMASEIAEPAAAARLGAAGAEVIRAPDCQRTPG
HHHHHHHHHCCCCCCHHHHHCCCCCCEEHHHHHCCHHHHHHHCCCCHHHHCCCCCCCCCC
LDIAAVLAALSEKGVTRLLVEGGARAARAFVESGLVDEIWLLRGDKAIGEDGVDALDGLP
CCHHHHHHHHHHCCCEEEEHHCCHHHHHHHHHCCCHHHHHEEECCCCCCCCCCHHHCCCC
LASITASSAWRVRDSERLGPDTLTIFEPA
CCEECCCCCEEECCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]