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The map label for this gene is nrdR [H]

Identifier: 86749752

GI number: 86749752

Start: 3016008

End: 3016490

Strand: Direct

Name: nrdR [H]

Synonym: RPB_2635

Alternate gene names: 86749752

Gene position: 3016008-3016490 (Clockwise)

Preceding gene: 86749751

Following gene: 86749753

Centisome position: 56.57

GC content: 65.84

Gene sequence:

>483_bases
ATGCGGTGCCCGAACTGCAACAGCCTCGATACCCAGGTGAAGGACTCCAGGCCCACCGAGGATTCCTCGGTGATCCGGCG
GCGACGGGTCTGCATCGCCTGCAATTTCCGCTTCACCACCTTCGAGCGGGTGCAGCTCCGCGAGCTGACGGTGATCAAGC
GCAACGGCCGCCGGGTGCCGTTCGATCGCGACAAGCTGGTGCGCTCGCTGCAGATCAGCCTGCGCAAGCGGCCGGTCGAG
CCGGAGCGGGTCGAGCAGATGGTATCGGCGATCGTGCGCGAGCTGGAAAGCGGCGGCGAGGCCGACATCTCGTCGGAGAC
CATCGGCGAGATCGTGATGGACCATCTGCGCAAGCTCGACGACGTCGCTTATGTGCGGTTCGCCTCGGTGTATCGCAATT
TCCGCGAGGCCAAGGACTTCGAGGCGGTGCTCGGCGAATTGTCCGGCGAGGAGGAGGCCCGGCCGGCGCTGGTCCGCAAA
TGA

Upstream 100 bases:

>100_bases
TACGGCGTGGCAGCGGGAGCAAGGCGTGGATGGCCGGGACGAGCCCGGCCATGACGGAGAAGGGGGCCAGCCCTCCGGAA
AGCACTGAGGACGCGTCGAG

Downstream 100 bases:

>100_bases
TCTTCCGCATCCTGGAAGACCAATATGCCGAGCGCGCCAAGGTCGAAAAGGCCGCCAAGGCAGCCGCCGCCACTGATCGC
CGCTTCATGCAGCTCGCGCT

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MRCPNCNSLDTQVKDSRPTEDSSVIRRRRVCIACNFRFTTFERVQLRELTVIKRNGRRVPFDRDKLVRSLQISLRKRPVE
PERVEQMVSAIVRELESGGEADISSETIGEIVMDHLRKLDDVAYVRFASVYRNFREAKDFEAVLGELSGEEEARPALVRK

Sequences:

>Translated_160_residues
MRCPNCNSLDTQVKDSRPTEDSSVIRRRRVCIACNFRFTTFERVQLRELTVIKRNGRRVPFDRDKLVRSLQISLRKRPVE
PERVEQMVSAIVRELESGGEADISSETIGEIVMDHLRKLDDVAYVRFASVYRNFREAKDFEAVLGELSGEEEARPALVRK
>Mature_160_residues
MRCPNCNSLDTQVKDSRPTEDSSVIRRRRVCIACNFRFTTFERVQLRELTVIKRNGRRVPFDRDKLVRSLQISLRKRPVE
PERVEQMVSAIVRELESGGEADISSETIGEIVMDHLRKLDDVAYVRFASVYRNFREAKDFEAVLGELSGEEEARPALVRK

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=154, Percent_Identity=46.1038961038961, Blast_Score=131, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 18557; Mature: 18557

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPNCNSLDTQVKDSRPTEDSSVIRRRRVCIACNFRFTTFERVQLRELTVIKRNGRRVP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCCCCCCC
FDRDKLVRSLQISLRKRPVEPERVEQMVSAIVRELESGGEADISSETIGEIVMDHLRKLD
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
DVAYVRFASVYRNFREAKDFEAVLGELSGEEEARPALVRK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCC
>Mature Secondary Structure
MRCPNCNSLDTQVKDSRPTEDSSVIRRRRVCIACNFRFTTFERVQLRELTVIKRNGRRVP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCCCCCCC
FDRDKLVRSLQISLRKRPVEPERVEQMVSAIVRELESGGEADISSETIGEIVMDHLRKLD
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
DVAYVRFASVYRNFREAKDFEAVLGELSGEEEARPALVRK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA