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The map label for this gene is bla [H]

Identifier: 86749460

GI number: 86749460

Start: 2688566

End: 2689384

Strand: Direct

Name: bla [H]

Synonym: RPB_2340

Alternate gene names: 86749460

Gene position: 2688566-2689384 (Clockwise)

Preceding gene: 86749459

Following gene: 86749462

Centisome position: 50.43

GC content: 67.77

Gene sequence:

>819_bases
TTGCTCACCCGCCGTTCCGCCCTCGGCCTCTGCGCCGCCGCCCTGCTACCCACCCCCCGGGCGTTTGCGGAGGTCGCGCC
GCCGCGCAGTGAAATCCGCGCCAGCCTCGCCAAACGTTTCACCGACGAGGGCACGGCAGGGACTTTCGTCGGCTACAAGA
CCGACGACTACCTGATCATCGCCAGCGATGCGCAGCGCTCCGGCGAAGCGTTCCTGCCGGCCTCGACCTTCAAGGTGCCG
AACTCGCTGATCGCGCTCGAGACCGGCGTGGTCGGCGATCCGGACAAGGATGTGTTCAAGTGGGACGGCGTCACCCGCGG
CATCGAGGCGTGGAATCGCGACCACACGCTGCGCAGCGCGATCGCGGCCTCGGCGGTGCCGGTGTATCAGGAGATCGCCC
GCCGCATCGGCGCCGAGAGAATGCAGAACTACGTGAATTTGTTCGACTACGGCAACCGCAACATTGGCGGCGGCATCGAC
CGGTTCTGGCTGACCGGCGATCTGCGGATCGACTGCATTCAGCAGATCGACTTCCTCGACCGGCTGCGCCGCCGCGCGCT
GCCGATCGGAAAGCGCAGCCAGGATCTGGTCGTCGACATCCTGCCGGTGACGAAAGTCGGCGATGCGGTGATCCGCGCCA
AGACCGGGCTGCTCGGCGCCGAGAAGGGCCAGCCGTCGCTCGGCTGGCTGGTCGGCTGGGCCGAGAAGGGCGATCGGCAG
ACGGTGTTCGCGCTCAATCTCGACGCAAGCGAACCGCGCCACGCCGCGGCGCGGATGACGCTGGCGCAGAAGTGTCTGGC
GGATATCGGCGCGATCTGA

Upstream 100 bases:

>100_bases
CGCTCCTCGCAATGACGGTGAGGTTGATAGCTCGACGGCCATCGTTTCACCACGAGCCTCGCGCATCGTCCGCGCTTTAT
CCATCCTCGAGGATCATCCA

Downstream 100 bases:

>100_bases
ACGCTTAGTTCGCCTCGGCGGGACCGGCAGCGACGGGCTTGCGCTTGCCGAGCCGGCCGAGATGGGTGTCGTGGAAGCTC
GATCCGTATTTCAGGCCGAA

Product: twin-arginine translocation pathway signal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MLTRRSALGLCAAALLPTPRAFAEVAPPRSEIRASLAKRFTDEGTAGTFVGYKTDDYLIIASDAQRSGEAFLPASTFKVP
NSLIALETGVVGDPDKDVFKWDGVTRGIEAWNRDHTLRSAIAASAVPVYQEIARRIGAERMQNYVNLFDYGNRNIGGGID
RFWLTGDLRIDCIQQIDFLDRLRRRALPIGKRSQDLVVDILPVTKVGDAVIRAKTGLLGAEKGQPSLGWLVGWAEKGDRQ
TVFALNLDASEPRHAAARMTLAQKCLADIGAI

Sequences:

>Translated_272_residues
MLTRRSALGLCAAALLPTPRAFAEVAPPRSEIRASLAKRFTDEGTAGTFVGYKTDDYLIIASDAQRSGEAFLPASTFKVP
NSLIALETGVVGDPDKDVFKWDGVTRGIEAWNRDHTLRSAIAASAVPVYQEIARRIGAERMQNYVNLFDYGNRNIGGGID
RFWLTGDLRIDCIQQIDFLDRLRRRALPIGKRSQDLVVDILPVTKVGDAVIRAKTGLLGAEKGQPSLGWLVGWAEKGDRQ
TVFALNLDASEPRHAAARMTLAQKCLADIGAI
>Mature_272_residues
MLTRRSALGLCAAALLPTPRAFAEVAPPRSEIRASLAKRFTDEGTAGTFVGYKTDDYLIIASDAQRSGEAFLPASTFKVP
NSLIALETGVVGDPDKDVFKWDGVTRGIEAWNRDHTLRSAIAASAVPVYQEIARRIGAERMQNYVNLFDYGNRNIGGGID
RFWLTGDLRIDCIQQIDFLDRLRRRALPIGKRSQDLVVDILPVTKVGDAVIRAKTGLLGAEKGQPSLGWLVGWAEKGDRQ
TVFALNLDASEPRHAAARMTLAQKCLADIGAI

Specific function: Hydrolyzes both oxacillin and methicillin [H]

COG id: COG2602

COG function: function code V; Beta-lactamase class D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-D beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR002137
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00905 Transpeptidase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 29679; Mature: 29679

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS00337 BETA_LACTAMASE_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTRRSALGLCAAALLPTPRAFAEVAPPRSEIRASLAKRFTDEGTAGTFVGYKTDDYLII
CCCCHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEE
ASDAQRSGEAFLPASTFKVPNSLIALETGVVGDPDKDVFKWDGVTRGIEAWNRDHTLRSA
ECCCCCCCCEECCCHHHCCCCCEEEEECCCCCCCCCCCEEECCHHHHHHHHCCCHHHHHH
IAASAVPVYQEIARRIGAERMQNYVNLFDYGNRNIGGGIDRFWLTGDLRIDCIQQIDFLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHH
RLRRRALPIGKRSQDLVVDILPVTKVGDAVIRAKTGLLGAEKGQPSLGWLVGWAEKGDRQ
HHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCE
TVFALNLDASEPRHAAARMTLAQKCLADIGAI
EEEEEECCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTRRSALGLCAAALLPTPRAFAEVAPPRSEIRASLAKRFTDEGTAGTFVGYKTDDYLII
CCCCHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEE
ASDAQRSGEAFLPASTFKVPNSLIALETGVVGDPDKDVFKWDGVTRGIEAWNRDHTLRSA
ECCCCCCCCEECCCHHHCCCCCEEEEECCCCCCCCCCCEEECCHHHHHHHHCCCHHHHHH
IAASAVPVYQEIARRIGAERMQNYVNLFDYGNRNIGGGIDRFWLTGDLRIDCIQQIDFLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHH
RLRRRALPIGKRSQDLVVDILPVTKVGDAVIRAKTGLLGAEKGQPSLGWLVGWAEKGDRQ
HHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCE
TVFALNLDASEPRHAAARMTLAQKCLADIGAI
EEEEEECCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1495394 [H]