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The map label for this gene is degQ [H]

Identifier: 86749443

GI number: 86749443

Start: 2671433

End: 2672824

Strand: Direct

Name: degQ [H]

Synonym: RPB_2323

Alternate gene names: 86749443

Gene position: 2671433-2672824 (Clockwise)

Preceding gene: 86749441

Following gene: 86749444

Centisome position: 50.11

GC content: 68.32

Gene sequence:

>1392_bases
ATGTCCGCTGTCCGCATCTTCACGGCCGTCCTGCTCTCGCTCGCGGCGTCGGCCCCGGCGACCGCGCAGGAGCGGCGGCT
GCCGGCGTCGCAGGCCGAGATCAAGCTCAGCTACGCGCCGATCGTGCAGCACGCGCAGCCGGCGGTGGTGAACGTCTACG
CCGCCAAGGTGGTGCAGAACCGCAATCCGCTCTTGGAAGACCCGATCTTCCGCCGCTTCTTCGGCGGCGGCCCGCAGCCC
GAGCAGATCCAGCGCTCGCTCGGAAGCGGCGTGATGGTCGATCCGTCGGGCCTCGTCGTCACCAACAATCACGTCATCGA
CGGCGCCGATCAGGTCAAGGTCGCGCTCGCCGACAAGCGCGAGTTCGAGGCCGAGATCGTGCTGAAGGACAGCCGCACCG
ATCTCGCGGTGCTGCGCCTCAAGGATACCAGGGAGAAATTCGCCACCCTCGAACTGGCCAATTCGGACGAGCTGCTGGTC
GGCGATCTGGTGCTGGCGTTGGGCAATCCGTTCGGCGTCGGCCAGACCGTGACGCACGGCATCGTCTCGGCGCTGGCGCG
CACCCAGGTCGGCATCACCGACTATCAGTTCTTCATCCAGACCGACGCGGCGATCAATCCCGGCAATTCCGGCGGCGCGC
TGGTCGACATGACCGGCAAGCTGGTCGGCATCAACACCGCGATCTTTTCGCGCTCCGGCGGCTCGCAGGGCATCGGCTTC
GCGATCCCGACCAACATGGTGCGGGTGGTGATCGCCTCGGCCAAGAGCGGCGGCAAGGCGGTGAAGCGGCCGTGGCTCGG
CGCGCGGCTGCAGGCGGTGACGCCGGAGATCGCCGAGACGCTCGGTCTGAAGCGGCCCAGCGGCGCGCTGGTGGCGAGCG
TCACCAAGGGCAGCCCGTCCGACAAGGCGGGGCTGAGACTGTCCGATCTGATCGTCGGGGTCGACGGCTTTGCGATCGAT
GATCCCAACGCGTTCGACTATCGCTTCGCCACCCGCCCGCTCGGCGGCACCGCGCAGATCGACGTGCAGCGCGGCGGCAA
GCCGCTCAAGCTCAGCATCACGCTGGAGACCGCGCCGGACACCGGCCGCGACGAGATCGTGCTGACCGCGCGCTCGCCGT
TCCAGGGTGCCAGGATCGCCAACATCTCGCCGGCGATCGCCGACGACCTGCGGCTCGACCCCAGCGTCGAGGGCGTGGTC
GTGACCGATCTCGCCGACGGCGCCACCGCGGCGAGCGTCGGTTTCCAGAAGGGCGACATCATCGTCGCGGTCAACAACAA
GCGCATCGGCAAGACCAGCGACCTCGAACGCATCACCAACGAGTCGTTCCGCCTGTGGCGCATCACCGTCGTTCGCGGCG
GCCAGCAGATCAACGTCACGCTCGGCGGATGA

Upstream 100 bases:

>100_bases
CGGCGCTGCGCCGGAAGGCTACAATCCGCCGCTTTTGACCGCTTCGATTCGCGCAGGCTGCGTCGATCACGCGGCCGCTT
CAACTCTGGAACATCGCCTC

Downstream 100 bases:

>100_bases
GCACGACCGCAGCGCTGCTCCCAACCTCTCCCCGCGCGCGGGGAGAGGTCGCCCGGCGTAGCGTCAGCGAAGCCGGGCGG
GTGAGGGGGCGCTTCAGCAA

Product: peptidase S1C, Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MSAVRIFTAVLLSLAASAPATAQERRLPASQAEIKLSYAPIVQHAQPAVVNVYAAKVVQNRNPLLEDPIFRRFFGGGPQP
EQIQRSLGSGVMVDPSGLVVTNNHVIDGADQVKVALADKREFEAEIVLKDSRTDLAVLRLKDTREKFATLELANSDELLV
GDLVLALGNPFGVGQTVTHGIVSALARTQVGITDYQFFIQTDAAINPGNSGGALVDMTGKLVGINTAIFSRSGGSQGIGF
AIPTNMVRVVIASAKSGGKAVKRPWLGARLQAVTPEIAETLGLKRPSGALVASVTKGSPSDKAGLRLSDLIVGVDGFAID
DPNAFDYRFATRPLGGTAQIDVQRGGKPLKLSITLETAPDTGRDEIVLTARSPFQGARIANISPAIADDLRLDPSVEGVV
VTDLADGATAASVGFQKGDIIVAVNNKRIGKTSDLERITNESFRLWRITVVRGGQQINVTLGG

Sequences:

>Translated_463_residues
MSAVRIFTAVLLSLAASAPATAQERRLPASQAEIKLSYAPIVQHAQPAVVNVYAAKVVQNRNPLLEDPIFRRFFGGGPQP
EQIQRSLGSGVMVDPSGLVVTNNHVIDGADQVKVALADKREFEAEIVLKDSRTDLAVLRLKDTREKFATLELANSDELLV
GDLVLALGNPFGVGQTVTHGIVSALARTQVGITDYQFFIQTDAAINPGNSGGALVDMTGKLVGINTAIFSRSGGSQGIGF
AIPTNMVRVVIASAKSGGKAVKRPWLGARLQAVTPEIAETLGLKRPSGALVASVTKGSPSDKAGLRLSDLIVGVDGFAID
DPNAFDYRFATRPLGGTAQIDVQRGGKPLKLSITLETAPDTGRDEIVLTARSPFQGARIANISPAIADDLRLDPSVEGVV
VTDLADGATAASVGFQKGDIIVAVNNKRIGKTSDLERITNESFRLWRITVVRGGQQINVTLGG
>Mature_462_residues
SAVRIFTAVLLSLAASAPATAQERRLPASQAEIKLSYAPIVQHAQPAVVNVYAAKVVQNRNPLLEDPIFRRFFGGGPQPE
QIQRSLGSGVMVDPSGLVVTNNHVIDGADQVKVALADKREFEAEIVLKDSRTDLAVLRLKDTREKFATLELANSDELLVG
DLVLALGNPFGVGQTVTHGIVSALARTQVGITDYQFFIQTDAAINPGNSGGALVDMTGKLVGINTAIFSRSGGSQGIGFA
IPTNMVRVVIASAKSGGKAVKRPWLGARLQAVTPEIAETLGLKRPSGALVASVTKGSPSDKAGLRLSDLIVGVDGFAIDD
PNAFDYRFATRPLGGTAQIDVQRGGKPLKLSITLETAPDTGRDEIVLTARSPFQGARIANISPAIADDLRLDPSVEGVVV
TDLADGATAASVGFQKGDIIVAVNNKRIGKTSDLERITNESFRLWRITVVRGGQQINVTLGG

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=345, Percent_Identity=32.463768115942, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI4506141, Length=245, Percent_Identity=35.5102040816327, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI7019477, Length=334, Percent_Identity=33.8323353293413, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI24308541, Length=245, Percent_Identity=35.1020408163265, Blast_Score=132, Evalue=9e-31,
Organism=Escherichia coli, GI1789629, Length=456, Percent_Identity=36.4035087719298, Blast_Score=261, Evalue=9e-71,
Organism=Escherichia coli, GI1786356, Length=467, Percent_Identity=35.117773019272, Blast_Score=247, Evalue=9e-67,
Organism=Escherichia coli, GI1789630, Length=336, Percent_Identity=38.9880952380952, Blast_Score=190, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24646839, Length=305, Percent_Identity=32.7868852459016, Blast_Score=128, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 48782; Mature: 48651

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVRIFTAVLLSLAASAPATAQERRLPASQAEIKLSYAPIVQHAQPAVVNVYAAKVVQN
CCHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHEEEEEEHHHHHCCCCCEEEHEEHHHHHC
RNPLLEDPIFRRFFGGGPQPEQIQRSLGSGVMVDPSGLVVTNNHVIDGADQVKVALADKR
CCCCCCCHHHHHHHCCCCCHHHHHHHHCCCEEECCCCEEEECCEEECCCCEEEEEEECCC
EFEAEIVLKDSRTDLAVLRLKDTREKFATLELANSDELLVGDLVLALGNPFGVGQTVTHG
CCCEEEEEECCCCCEEEEEECCCHHHEEEEEECCCCCEEEEEEHHHCCCCCCCCHHHHHH
IVSALARTQVGITDYQFFIQTDAAINPGNSGGALVDMTGKLVGINTAIFSRSGGSQGIGF
HHHHHHHHCCCCEEEEEEEEECCEECCCCCCCEEEEECCEEEEEEEEEEECCCCCCCCEE
AIPTNMVRVVIASAKSGGKAVKRPWLGARLQAVTPEIAETLGLKRPSGALVASVTKGSPS
ECCHHEEEEEEEECCCCCCHHCCCCCCCEEECCCHHHHHHHCCCCCCCCEEEEEECCCCC
DKAGLRLSDLIVGVDGFAIDDPNAFDYRFATRPLGGTAQIDVQRGGKPLKLSITLETAPD
CCCCCEEEHEEEECCCEEECCCCCCEEEEECCCCCCCEEEEEECCCCEEEEEEEEEECCC
TGRDEIVLTARSPFQGARIANISPAIADDLRLDPSVEGVVVTDLADGATAASVGFQKGDI
CCCCCEEEEECCCCCCCEECCCCCCHHHCCCCCCCCCCEEEEECCCCCCCHHCCCCCCCE
IVAVNNKRIGKTSDLERITNESFRLWRITVVRGGQQINVTLGG
EEEECCCCCCCCHHHHHHCCCCEEEEEEEEEECCCEEEEEECC
>Mature Secondary Structure 
SAVRIFTAVLLSLAASAPATAQERRLPASQAEIKLSYAPIVQHAQPAVVNVYAAKVVQN
CHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHEEEEEEHHHHHCCCCCEEEHEEHHHHHC
RNPLLEDPIFRRFFGGGPQPEQIQRSLGSGVMVDPSGLVVTNNHVIDGADQVKVALADKR
CCCCCCCHHHHHHHCCCCCHHHHHHHHCCCEEECCCCEEEECCEEECCCCEEEEEEECCC
EFEAEIVLKDSRTDLAVLRLKDTREKFATLELANSDELLVGDLVLALGNPFGVGQTVTHG
CCCEEEEEECCCCCEEEEEECCCHHHEEEEEECCCCCEEEEEEHHHCCCCCCCCHHHHHH
IVSALARTQVGITDYQFFIQTDAAINPGNSGGALVDMTGKLVGINTAIFSRSGGSQGIGF
HHHHHHHHCCCCEEEEEEEEECCEECCCCCCCEEEEECCEEEEEEEEEEECCCCCCCCEE
AIPTNMVRVVIASAKSGGKAVKRPWLGARLQAVTPEIAETLGLKRPSGALVASVTKGSPS
ECCHHEEEEEEEECCCCCCHHCCCCCCCEEECCCHHHHHHHCCCCCCCCEEEEEECCCCC
DKAGLRLSDLIVGVDGFAIDDPNAFDYRFATRPLGGTAQIDVQRGGKPLKLSITLETAPD
CCCCCEEEHEEEECCCEEECCCCCCEEEEECCCCCCCEEEEEECCCCEEEEEEEEEECCC
TGRDEIVLTARSPFQGARIANISPAIADDLRLDPSVEGVVVTDLADGATAASVGFQKGDI
CCCCCEEEEECCCCCCCEECCCCCCHHHCCCCCCCCCCEEEEECCCCCCCHHCCCCCCCE
IVAVNNKRIGKTSDLERITNESFRLWRITVVRGGQQINVTLGG
EEEECCCCCCCCHHHHHHCCCCEEEEEEEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]