BacMap

Definition	Rhodopseudomonas palustris HaA2, complete genome.
Accession	NC_007778
Length	5,331,656

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The map label for this gene is yvaG [H]

Identifier: 86749441

GI number: 86749441

Start: 2669174

End: 2669968

Strand: Direct

Name: yvaG [H]

Synonym: RPB_2321

Alternate gene names: 86749441

Gene position: 2669174-2669968 (Clockwise)

Preceding gene: 86749440

Following gene: 86749443

Centisome position: 50.06

GC content: 67.42

Gene sequence:

>795_bases
ATGCACATCAATCTCTCCGGCAAGACCGCGCTGGTCACCGGCTCGACGGCGGGCATCGGCCACGCCATCGCCAGGGGGCT
CGCCGCGGCCGGCGCCGAGGTCGTGGTCAACGGCCGCAGCCAGGCCAAGGTCGACGCCGCGCAGGCCGCGATCGACAAGG
CGGTGCCGGGCGCCAAGCTGTGCGGCGTCGCCGCCGATGTCTCCACCGCGGAGGGCTGCGCCGCGCTGCTGGTCGCGATT
CCGCGCGTCGACATCCTGATCAACAATGCCGGCATCTTCGAACCGAAGGGCTTCTTCGACATTCCGGACGCCGACTGGCA
GCGCTTCTTCGACGTCAATGTGATGAGCGGCGTGCGGCTGTCGCGCGGCTACATGCCGGGGATGCTCGAGCGTAATTGGG
GCCGCATCGTCTTCATCGCCTCGGAATCCGCGCTCATGATTCCGAAGGAGATGATCCACTACGGCATGACCAAGACCGCG
CAGCTCTCGGTGTCGCGCGGCCTCGCGGAGATGACCCGCGGCACCGCGGTGACGGTCAATGCGGTGATGCCGGGACCGAC
GATGAGCGAAGGCGTGCAGACCTTCGTCGCCGATCTGGCCAAGCAGAACGGCCAGTCGGAGGCCGAGGCGGCGGCCAATT
TCGTCAAGCAGCATCGCCCCGGCTCACTGATCCAGCGCTTCGCTACCGTCGAGGAGATCGCCAACATGGTGGTCTATGTC
AGCTCCAAGGAAGCCTCCGCCACCAACGGCGCCGCGCTGCGCGCCGAAGGCGGGCTCTTGCAGACGATCGCGTAG

Upstream 100 bases:

>100_bases
GCAGCAAGCGCTGCACACGAAATCGCGTCTTGCGCTCACGACCATCGCTTCCGACGTTACGTCAGCTATCGCGCCGAGCA
ATGTAACGAGGAGCAACCAC

Downstream 100 bases:

>100_bases
TTCGTCGAGCTTAGTTCATTGTCTCAGTGCTCGGCTCGCCCTCACTCCAACCCTCTCCCGCAAGCGGGAGAGGGGGCGCG
TTGCCGCTTGGATAAGCGCA

Product: Short-chain dehydrogenase/reductase SDR

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MHINLSGKTALVTGSTAGIGHAIARGLAAAGAEVVVNGRSQAKVDAAQAAIDKAVPGAKLCGVAADVSTAEGCAALLVAI
PRVDILINNAGIFEPKGFFDIPDADWQRFFDVNVMSGVRLSRGYMPGMLERNWGRIVFIASESALMIPKEMIHYGMTKTA
QLSVSRGLAEMTRGTAVTVNAVMPGPTMSEGVQTFVADLAKQNGQSEAEAAANFVKQHRPGSLIQRFATVEEIANMVVYV
SSKEASATNGAALRAEGGLLQTIA

Sequences:

>Translated_264_residues
MHINLSGKTALVTGSTAGIGHAIARGLAAAGAEVVVNGRSQAKVDAAQAAIDKAVPGAKLCGVAADVSTAEGCAALLVAI
PRVDILINNAGIFEPKGFFDIPDADWQRFFDVNVMSGVRLSRGYMPGMLERNWGRIVFIASESALMIPKEMIHYGMTKTA
QLSVSRGLAEMTRGTAVTVNAVMPGPTMSEGVQTFVADLAKQNGQSEAEAAANFVKQHRPGSLIQRFATVEEIANMVVYV
SSKEASATNGAALRAEGGLLQTIA
>Mature_264_residues
MHINLSGKTALVTGSTAGIGHAIARGLAAAGAEVVVNGRSQAKVDAAQAAIDKAVPGAKLCGVAADVSTAEGCAALLVAI
PRVDILINNAGIFEPKGFFDIPDADWQRFFDVNVMSGVRLSRGYMPGMLERNWGRIVFIASESALMIPKEMIHYGMTKTA
QLSVSRGLAEMTRGTAVTVNAVMPGPTMSEGVQTFVADLAKQNGQSEAEAAANFVKQHRPGSLIQRFATVEEIANMVVYV
SSKEASATNGAALRAEGGLLQTIA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=262, Percent_Identity=29.7709923664122, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI5031737, Length=251, Percent_Identity=31.0756972111554, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI7705855, Length=189, Percent_Identity=32.8042328042328, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI7705925, Length=260, Percent_Identity=27.6923076923077, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI66933014, Length=261, Percent_Identity=27.2030651340996, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=29.8387096774194, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI126723191, Length=170, Percent_Identity=34.1176470588235, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI33667109, Length=186, Percent_Identity=34.4086021505376, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4504505, Length=200, Percent_Identity=31, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI126723750, Length=263, Percent_Identity=27.3764258555133, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI10190746, Length=210, Percent_Identity=27.6190476190476, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI31542939, Length=194, Percent_Identity=30.9278350515464, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI7657478, Length=189, Percent_Identity=31.7460317460317, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787335, Length=265, Percent_Identity=32.0754716981132, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=29.7709923664122, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1787905, Length=267, Percent_Identity=31.0861423220974, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790717, Length=263, Percent_Identity=26.2357414448669, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=29.8449612403101, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082160, Length=264, Percent_Identity=25.7575757575758, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=32.4175824175824, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789208, Length=264, Percent_Identity=25.7575757575758, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788459, Length=259, Percent_Identity=26.6409266409266, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI2367175, Length=259, Percent_Identity=29.7297297297297, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=29.6153846153846, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17560676, Length=260, Percent_Identity=30, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI193204405, Length=272, Percent_Identity=30.8823529411765, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=27.843137254902, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=28.0155642023346, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=202, Percent_Identity=30.6930693069307, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=28.6792452830189, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=261, Percent_Identity=28.735632183908, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=269, Percent_Identity=26.7657992565056, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=274, Percent_Identity=28.1021897810219, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=191, Percent_Identity=30.8900523560209, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=276, Percent_Identity=27.1739130434783, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=142, Percent_Identity=33.8028169014084, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=267, Percent_Identity=26.5917602996255, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=272, Percent_Identity=26.8382352941176, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=27.6119402985075, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=198, Percent_Identity=32.3232323232323, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=268, Percent_Identity=29.1044776119403, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI32565532, Length=142, Percent_Identity=32.3943661971831, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=266, Percent_Identity=28.1954887218045, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=204, Percent_Identity=30.3921568627451, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=276, Percent_Identity=27.536231884058, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=195, Percent_Identity=31.7948717948718, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=193, Percent_Identity=33.160621761658, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=196, Percent_Identity=32.1428571428571, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=254, Percent_Identity=28.740157480315, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=162, Percent_Identity=31.4814814814815, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=27.6041666666667, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=249, Percent_Identity=26.9076305220884, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355319, Length=260, Percent_Identity=30.3846153846154, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=26.6409266409266, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24643142, Length=258, Percent_Identity=27.5193798449612, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=27.4509803921569, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24639444, Length=262, Percent_Identity=28.6259541984733, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571526, Length=255, Percent_Identity=29.0196078431373, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI18859837, Length=200, Percent_Identity=30, Blast_Score=78, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 27530; Mature: 27530

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHINLSGKTALVTGSTAGIGHAIARGLAAAGAEVVVNGRSQAKVDAAQAAIDKAVPGAKL
CEEECCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCHHH
CGVAADVSTAEGCAALLVAIPRVDILINNAGIFEPKGFFDIPDADWQRFFDVNVMSGVRL
HEECCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCHHHHEEECHHHCCCCC
SRGYMPGMLERNWGRIVFIASESALMIPKEMIHYGMTKTAQLSVSRGLAEMTRGTAVTVN
CCCCCCCCCCCCCCEEEEEECCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEE
AVMPGPTMSEGVQTFVADLAKQNGQSEAEAAANFVKQHRPGSLIQRFATVEEIANMVVYV
EECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCEEEEE
SSKEASATNGAALRAEGGLLQTIA
ECCCCCCCCCCEEEECCCEEECCC
>Mature Secondary Structure
MHINLSGKTALVTGSTAGIGHAIARGLAAAGAEVVVNGRSQAKVDAAQAAIDKAVPGAKL
CEEECCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCHHH
CGVAADVSTAEGCAALLVAIPRVDILINNAGIFEPKGFFDIPDADWQRFFDVNVMSGVRL
HEECCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCHHHHEEECHHHCCCCC
SRGYMPGMLERNWGRIVFIASESALMIPKEMIHYGMTKTAQLSVSRGLAEMTRGTAVTVN
CCCCCCCCCCCCCCEEEEEECCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEE
AVMPGPTMSEGVQTFVADLAKQNGQSEAEAAANFVKQHRPGSLIQRFATVEEIANMVVYV
EECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCEEEEE
SSKEASATNGAALRAEGGLLQTIA
ECCCCCCCCCCEEEECCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]