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The map label for this gene is glnA [H]

Identifier: 86749389

GI number: 86749389

Start: 2619081

End: 2620511

Strand: Direct

Name: glnA [H]

Synonym: RPB_2269

Alternate gene names: 86749389

Gene position: 2619081-2620511 (Clockwise)

Preceding gene: 86749388

Following gene: 86749390

Centisome position: 49.12

GC content: 64.64

Gene sequence:

>1431_bases
TTGAGTCTGGTTGAGAAGTACGGGCTCTGGTCCGACGAACAGATCGAGGCTGCCGCGAGGATGCGGCAGACCGCCGAGGA
GCATGGTCTCGAGACCATCCGCTTCTCGTTTCCCGATCAGCACGGCATCCTGCGCGGCAAGACGCTGGTGGCGTCCGAAG
CGCTGAACTGCCTCGAATCCGGCGCCTCCATCACGACGACGATGCTGGCCAAGGACACTTCGCACAAGACGGTGTTTCCG
GTGTTTCAGGCCGGCGGCGGCTTCGGCATGTCGGAGATGCAGGGCGGCGCCGACGCCATCATGCTGCCGGATCCCACGAC
ATTCCGCGTGCTGCCTTGGGCGCCGAACACCGGGTGGGTGTTGTGCGATCTGTATTTTGCCAATGGTCGCGCCGTTCCGT
TCGCGACGCGCGGGCTGTATCGCTCGGTGCTGCAGAAACTCGCCGATCGCGGCTACGACTACATGGCCGGGCTCGAGGTC
GAATTCCACGTCTTCAAGGTCGAGGACGGCAAGATGCGGCCGGAGCACGCCGGCCAGCCCGGCGAGCCGCCCGAAGTCAG
CCTGTTGTCGCACGGTTATCAGTATCTCACCGAGCAGCGCTACGATCAGATGGAGCCGGTGCTCGAACTGATCCGCCGCG
ATATCGTCGCGCTCGGCCTGCCGCTGCGGTCGATCGAGGTCGAGTTCGGCCCGAGCCAATGCGAGTTCACCTTCCAGCCG
ACGGTGGGCTTGATGCCGGCGGACCTGATGGTGCTGTTCCGCAGCGCGGTGAAGCAGATCTGTCGGCGCCACGGCTATCA
CGCCACCTTCATGTGCCGCCCGCGTATTCCGAACGTGGTGTCGTCCGGCTGGCATCTGCACCAATGCCTGATCGCGCGTG
ACGGCGGCCACAACGCCTTCGTGTCGGAGACGGATGTGCTGTCCGACTTCGGCCGTCACTACCTCGCGGGGCTGCTGCAG
CATGCCCGCGCCGCGACCGTGTTCACCACGCCGACGATCAACGGCTACAAGCGCTACCGCTCCTATTCGCTGGCCCCCGA
TCGCGCGATCTGGGGACGCGACAATCGCGGCGTGATGCTGCGCGTGCTGGGTGGACCGGGTGATCGCGGCACGCGGATCG
AGAACCGGGTCGGCGAGCCTGCGGCAAACCCGTATCTTTACATGGCCTCGCAGATCCTGTCGGGTCTCGACGGCGTCGAC
CGCGCGCTCGATCCCGGGCCGTCAGCCGACACGCCCTACGAGACCAAGGCGGATCTTCTGCCCAAATCGCTGCGCGAGGC
GATCTTCGCGCTGCGCGACGATCCGTTCTTCCGCACCGCGCTGGGCGACGAGTTCGTCGACTACTACACGTTCATCAAGA
ATGCTGAAATCGAGCGCTTTCAGGCCGAAGTGACGGAGTGGGAGCAGCGCGAATATTTCGAAATGTTCTGA

Upstream 100 bases:

>100_bases
CCCTGGGCCGCGCCGGTGCCGGCGGAGATCGCCGCCAAGGTGCCGCATCTGACGGCGGCGGAATGAACGTGGGCAAACGA
CACGGATCGAGGATCGAGCG

Downstream 100 bases:

>100_bases
AGCCGAAATCACGAATTCGACAATCAACAGTGAGGAGAGACGTATGGGTTGGGGATTGCGATCTGTTTATGCACTCGCGG
CGGTCTCGTTGATCGCCACC

Product: glutamate--ammonia ligase

Products: NA

Alternate protein names: GS; Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MSLVEKYGLWSDEQIEAAARMRQTAEEHGLETIRFSFPDQHGILRGKTLVASEALNCLESGASITTTMLAKDTSHKTVFP
VFQAGGGFGMSEMQGGADAIMLPDPTTFRVLPWAPNTGWVLCDLYFANGRAVPFATRGLYRSVLQKLADRGYDYMAGLEV
EFHVFKVEDGKMRPEHAGQPGEPPEVSLLSHGYQYLTEQRYDQMEPVLELIRRDIVALGLPLRSIEVEFGPSQCEFTFQP
TVGLMPADLMVLFRSAVKQICRRHGYHATFMCRPRIPNVVSSGWHLHQCLIARDGGHNAFVSETDVLSDFGRHYLAGLLQ
HARAATVFTTPTINGYKRYRSYSLAPDRAIWGRDNRGVMLRVLGGPGDRGTRIENRVGEPAANPYLYMASQILSGLDGVD
RALDPGPSADTPYETKADLLPKSLREAIFALRDDPFFRTALGDEFVDYYTFIKNAEIERFQAEVTEWEQREYFEMF

Sequences:

>Translated_476_residues
MSLVEKYGLWSDEQIEAAARMRQTAEEHGLETIRFSFPDQHGILRGKTLVASEALNCLESGASITTTMLAKDTSHKTVFP
VFQAGGGFGMSEMQGGADAIMLPDPTTFRVLPWAPNTGWVLCDLYFANGRAVPFATRGLYRSVLQKLADRGYDYMAGLEV
EFHVFKVEDGKMRPEHAGQPGEPPEVSLLSHGYQYLTEQRYDQMEPVLELIRRDIVALGLPLRSIEVEFGPSQCEFTFQP
TVGLMPADLMVLFRSAVKQICRRHGYHATFMCRPRIPNVVSSGWHLHQCLIARDGGHNAFVSETDVLSDFGRHYLAGLLQ
HARAATVFTTPTINGYKRYRSYSLAPDRAIWGRDNRGVMLRVLGGPGDRGTRIENRVGEPAANPYLYMASQILSGLDGVD
RALDPGPSADTPYETKADLLPKSLREAIFALRDDPFFRTALGDEFVDYYTFIKNAEIERFQAEVTEWEQREYFEMF
>Mature_475_residues
SLVEKYGLWSDEQIEAAARMRQTAEEHGLETIRFSFPDQHGILRGKTLVASEALNCLESGASITTTMLAKDTSHKTVFPV
FQAGGGFGMSEMQGGADAIMLPDPTTFRVLPWAPNTGWVLCDLYFANGRAVPFATRGLYRSVLQKLADRGYDYMAGLEVE
FHVFKVEDGKMRPEHAGQPGEPPEVSLLSHGYQYLTEQRYDQMEPVLELIRRDIVALGLPLRSIEVEFGPSQCEFTFQPT
VGLMPADLMVLFRSAVKQICRRHGYHATFMCRPRIPNVVSSGWHLHQCLIARDGGHNAFVSETDVLSDFGRHYLAGLLQH
ARAATVFTTPTINGYKRYRSYSLAPDRAIWGRDNRGVMLRVLGGPGDRGTRIENRVGEPAANPYLYMASQILSGLDGVDR
ALDPGPSADTPYETKADLLPKSLREAIFALRDDPFFRTALGDEFVDYYTFIKNAEIERFQAEVTEWEQREYFEMF

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=462, Percent_Identity=27.0562770562771, Blast_Score=170, Evalue=3e-42,
Organism=Escherichia coli, GI87081870, Length=440, Percent_Identity=26.5909090909091, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI1790301, Length=228, Percent_Identity=32.4561403508772, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 53490; Mature: 53359

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVEKYGLWSDEQIEAAARMRQTAEEHGLETIRFSFPDQHGILRGKTLVASEALNCLES
CCCHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHC
GASITTTMLAKDTSHKTVFPVFQAGGGFGMSEMQGGADAIMLPDPTTFRVLPWAPNTGWV
CCCEEEEEEECCCCCCEEEEEEECCCCCCHHHHCCCCCEEECCCCCCEEEEECCCCCCEE
LCDLYFANGRAVPFATRGLYRSVLQKLADRGYDYMAGLEVEFHVFKVEDGKMRPEHAGQP
EEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCEEEEEEEEECCCCCCCHHCCCC
GEPPEVSLLSHGYQYLTEQRYDQMEPVLELIRRDIVALGLPLRSIEVEFGPSQCEFTFQP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECC
TVGLMPADLMVLFRSAVKQICRRHGYHATFMCRPRIPNVVSSGWHLHQCLIARDGGHNAF
CCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCEEEEEEEEECCCCCCC
VSETDVLSDFGRHYLAGLLQHARAATVFTTPTINGYKRYRSYSLAPDRAIWGRDNRGVML
CCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHCCCCCCCCCCCCCCCCCEEE
RVLGGPGDRGTRIENRVGEPAANPYLYMASQILSGLDGVDRALDPGPSADTPYETKADLL
EEECCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCHHHHH
PKSLREAIFALRDDPFFRTALGDEFVDYYTFIKNAEIERFQAEVTEWEQREYFEMF
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLVEKYGLWSDEQIEAAARMRQTAEEHGLETIRFSFPDQHGILRGKTLVASEALNCLES
CCHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHC
GASITTTMLAKDTSHKTVFPVFQAGGGFGMSEMQGGADAIMLPDPTTFRVLPWAPNTGWV
CCCEEEEEEECCCCCCEEEEEEECCCCCCHHHHCCCCCEEECCCCCCEEEEECCCCCCEE
LCDLYFANGRAVPFATRGLYRSVLQKLADRGYDYMAGLEVEFHVFKVEDGKMRPEHAGQP
EEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCEEEEEEEEECCCCCCCHHCCCC
GEPPEVSLLSHGYQYLTEQRYDQMEPVLELIRRDIVALGLPLRSIEVEFGPSQCEFTFQP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECC
TVGLMPADLMVLFRSAVKQICRRHGYHATFMCRPRIPNVVSSGWHLHQCLIARDGGHNAF
CCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCEEEEEEEEECCCCCCC
VSETDVLSDFGRHYLAGLLQHARAATVFTTPTINGYKRYRSYSLAPDRAIWGRDNRGVML
CCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHCCCCCCCCCCCCCCCCCEEE
RVLGGPGDRGTRIENRVGEPAANPYLYMASQILSGLDGVDRALDPGPSADTPYETKADLL
EEECCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCHHHHH
PKSLREAIFALRDDPFFRTALGDEFVDYYTFIKNAEIERFQAEVTEWEQREYFEMF
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7916055 [H]