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The map label for this gene is exbB [H]

Identifier: 86749211

GI number: 86749211

Start: 2376336

End: 2377277

Strand: Direct

Name: exbB [H]

Synonym: RPB_2090

Alternate gene names: 86749211

Gene position: 2376336-2377277 (Clockwise)

Preceding gene: 86749210

Following gene: 86749212

Centisome position: 44.57

GC content: 68.9

Gene sequence:

>942_bases
ATGAAACTGTCGAAAATTCGATCGATCACCGTCGCATTGGTTGCCGCGATCATGCTCGCGCCGATGGCGTCGGTGTTTGC
GCAGCCGGCGCCCGCGCAACCGTCTCCGGCGATGTCGACGCCCTCCGCCGCACAGCCGGCGGCCGCCCCGGAGAGGACGA
CCGCGCCCGAGACCACCGGCGCGACCCAGGCCGCAACCCAGGCCTTGCCTGCCTCCGGGACCACGCCGAACGGCAGCGTG
GCGCCGGGTCTCACGGAACTGTCGCCGTGGTCGATGTTCCTGCAGGCCGATATCGTCGTGAAGGCGGTGATGGTCGGTCT
GGCGCTCGCCTCGATGATCACCTGGACCATCCTCATCGCCAAGAAGATCGAACTCGGCCGCGCTCGCTGGCGGCTGCGCT
CGGCGCTGAAGCAGATCGCCGACGCGCGATCGATGTCCGAAGCGCAGCTCGCGCTCGGCGACAAGACCAGCCCGGTGTCG
ATGCTGCTCGCGGCGGCGCTGCGCGAGGCGCGGGTCTCGGCCGGGCTCGCCAGCGACGAGGGCATCAAGGAGCGCGCCGC
GTCGAGCTTCAGCGAAATCGTCCGCGCCGAGTCGCGGCACATGCGCCACGGCATGGGCTTCCTCGCCACCATCGGCGCGA
CCGCGCCGTTCATCGGCCTGTTCGGCACGGTGTGGGGCATCATGAACAGCTTCATCGGCATTTCGAAATCGCAGACCACC
AATCTGGCGGTGGTGGCGCCCGGTATCGCCGAGGCGCTGCTCGCCACCGCGATCGGCCTGGTCGCGGCGATTCCGGCGGT
GATCATCTACAATCACTTCTCGCGCGAGATTAAGGTCTATCTCGAAATGGTGGCGCGGGCGTCGGGCGCGGCGTTGCGGC
TGTTGTCGCGCGATCTCGATCGCAGCCACGGCACCGGCCGGCACGCGCGCGCGGCGGAGTAG

Upstream 100 bases:

>100_bases
GGGCCATTCAGGCTCTCGTCGAGCGGCTGGGACGAGATGACCCTGAAACGGTCAAATTGACCGGTATCTATCACAACCTC
ATCCGCTACTGGGCCGAAGT

Downstream 100 bases:

>100_bases
GCGATGGCGGTCTCGCTCAACGATTCCGACGGCCTCGACGACGATTTCGACGAGACCCACGAGATCAACGTCACGCCGTT
CATCGACGTGATGCTGGTGC

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MKLSKIRSITVALVAAIMLAPMASVFAQPAPAQPSPAMSTPSAAQPAAAPERTTAPETTGATQAATQALPASGTTPNGSV
APGLTELSPWSMFLQADIVVKAVMVGLALASMITWTILIAKKIELGRARWRLRSALKQIADARSMSEAQLALGDKTSPVS
MLLAAALREARVSAGLASDEGIKERAASSFSEIVRAESRHMRHGMGFLATIGATAPFIGLFGTVWGIMNSFIGISKSQTT
NLAVVAPGIAEALLATAIGLVAAIPAVIIYNHFSREIKVYLEMVARASGAALRLLSRDLDRSHGTGRHARAAE

Sequences:

>Translated_313_residues
MKLSKIRSITVALVAAIMLAPMASVFAQPAPAQPSPAMSTPSAAQPAAAPERTTAPETTGATQAATQALPASGTTPNGSV
APGLTELSPWSMFLQADIVVKAVMVGLALASMITWTILIAKKIELGRARWRLRSALKQIADARSMSEAQLALGDKTSPVS
MLLAAALREARVSAGLASDEGIKERAASSFSEIVRAESRHMRHGMGFLATIGATAPFIGLFGTVWGIMNSFIGISKSQTT
NLAVVAPGIAEALLATAIGLVAAIPAVIIYNHFSREIKVYLEMVARASGAALRLLSRDLDRSHGTGRHARAAE
>Mature_313_residues
MKLSKIRSITVALVAAIMLAPMASVFAQPAPAQPSPAMSTPSAAQPAAAPERTTAPETTGATQAATQALPASGTTPNGSV
APGLTELSPWSMFLQADIVVKAVMVGLALASMITWTILIAKKIELGRARWRLRSALKQIADARSMSEAQLALGDKTSPVS
MLLAAALREARVSAGLASDEGIKERAASSFSEIVRAESRHMRHGMGFLATIGATAPFIGLFGTVWGIMNSFIGISKSQTT
NLAVVAPGIAEALLATAIGLVAAIPAVIIYNHFSREIKVYLEMVARASGAALRLLSRDLDRSHGTGRHARAAE

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=218, Percent_Identity=54.5871559633027, Blast_Score=223, Evalue=9e-60,
Organism=Escherichia coli, GI1786958, Length=200, Percent_Identity=33.5, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 32602; Mature: 32602

Theoretical pI: Translated: 11.07; Mature: 11.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSKIRSITVALVAAIMLAPMASVFAQPAPAQPSPAMSTPSAAQPAAAPERTTAPETTG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ATQAATQALPASGTTPNGSVAPGLTELSPWSMFLQADIVVKAVMVGLALASMITWTILIA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKIELGRARWRLRSALKQIADARSMSEAQLALGDKTSPVSMLLAAALREARVSAGLASDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
GIKERAASSFSEIVRAESRHMRHGMGFLATIGATAPFIGLFGTVWGIMNSFIGISKSQTT
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NLAVVAPGIAEALLATAIGLVAAIPAVIIYNHFSREIKVYLEMVARASGAALRLLSRDLD
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RSHGTGRHARAAE
HCCCCCCCCCCCC
>Mature Secondary Structure
MKLSKIRSITVALVAAIMLAPMASVFAQPAPAQPSPAMSTPSAAQPAAAPERTTAPETTG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ATQAATQALPASGTTPNGSVAPGLTELSPWSMFLQADIVVKAVMVGLALASMITWTILIA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKIELGRARWRLRSALKQIADARSMSEAQLALGDKTSPVSMLLAAALREARVSAGLASDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
GIKERAASSFSEIVRAESRHMRHGMGFLATIGATAPFIGLFGTVWGIMNSFIGISKSQTT
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NLAVVAPGIAEALLATAIGLVAAIPAVIIYNHFSREIKVYLEMVARASGAALRLLSRDLD
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RSHGTGRHARAAE
HCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8437515 [H]